Abstract: Embodiments of the invention comprise a design tool for designing an application interface. The design tool includes a graphical user interface (GUI) that visually represents a hierarchy of data and the relationships between the data. Thus, the design tool eliminates the need for an interface designer to have independent knowledge of the structure of the data (i.e., the data fields and relationships between the data). The design tool's GUI represents the data and the relationships between the data in a hierarchical display referred to as a data palette. An output hierarchy comprised of output levels is created as the user selects fields from the data palette to be displayed in the application's interface. When a data field is selected, the design tool automatically determines the appropriate interface component and output level of the output hierarchy using the relationships defined for the data. Output levels are associated with interface components that comprise the application's interface.

Abstract: A system and associated methods are provided for smart hedging in an electronic trading environment. According to one example method, a first order for a first tradeable object and a second order for a second tradeable object are placed based on a spread strategy. Upon receiving an indication that a quantity of the first order is filled, the method involves determining if the second order can be used to offset the quantity filled of the first order by determining if a price of the second order would result in achieving a desired spread price defined for the spread strategy. If the price results in the desired price, the second order is used to offset the quantity filled for the first order in an attempt to achieve the desired spread price. Other tools are provided as well.

Abstract: Methods and systems for integrated transcoding on a plurality of data channels to convert one or more data channels from an incoming encoding format to an outgoing encoding format are disclosed.

Abstract: A system and associated methods are provided for smart hedging in an electronic trading environment. According to one example method, a first order for a first tradeable object and a second order for a second tradeable object are placed based on a spread strategy. Upon receiving an indication that a quantity of the first order is filled, the method involves determining if the second order can be used to offset the quantity filled of the first order by determining if a price of the second order would result in achieving a desired spread price defined for the spread strategy. If the price results in the desired price, the second order is used to offset the quantity filled for the first order in an attempt to achieve the desired spread price. Other tools are provided as well.

Abstract: A self-cleaning GMAW nozzle characterized by the inner surface thereof having a laminate group, preferably composed of sequentially alternating layers of metal and bonding material. Over a period of time of welding, welding spatter begins to accumulate upon an outermost metal layer of the laminate group. As the heat of welding proceeds over this same time, the adhesion of the adjoining bonding layer releases, whereby the outermost metal layer detaches, exposing a clean, new outermost metal layer. The process sequentially repeats until all metal layers have detached.

Abstract: The present invention provides pharmaceutical compositions comprising azelastine, or a pharmaceutically acceptable salt or ester thereof including azelastine hydrochloride, and optionally one or more additional active agents. Preferred such compositions further comprise one or more pharmaceutically acceptable carriers or excipients that reduce the amount of post-nasal drip, and/or that minimize or mask the unpleasant bitter taste associated with post-nasal drip, of the compositions into the oral cavity, upon intranasal or ocular administration of the compositions. Especially effective excipients used in the compositions of the present invention are hypromellose as a viscosity modifier and sucralose as a taste-masking agent.

Abstract: A goggle based light-weight VOG system includes at least one digital camera connected to and powered by a laptop computer through a firewire connection. The digital camera may digitally center the pupil in both the X and Y directions. A calibration mechanism may be incorporated onto the goggle base. An EOG system may also be incorporated directly into the goggle. The VOG system may track and record 3-D movement of the eye, track pupil dilation, head position and goggle slippage. An animated eye display provides data in a more meaningful fashion. The VOG system is a modular design whereby the same goggle frame or base is used to build a variety of digital camera VOG systems.

Abstract: Provided are methods of inhibiting BCL6 repression in a mammalian cell. Also provided are methods of treating cancer in a mammal.

Abstract: An image capturing device assembly for use with a test probe and a testing system. The image capturing device assembly including an image capturing device module configured for coupling to an external surface of the test probe and having an image capturing device housed within. The image capturing device is configured to generate a digital output video signal or the analog output video signal of a testing site. A digital monitor is coupled to the image capturing device via a wired or wireless link and configured to receive the digital output signal and generate a display of the testing site on the display monitor.

Abstract: Methods for treating cancer using compounds that inhibit human DNA ligases. Methods for using compounds that inhibit human DNA ligases to provide insights into the reaction mechanisms of human DNA ligases, for example to identify the human DNA ligase involved in different DNA repair pathways. Screening methods for compounds that inhibit human DNA ligases.

Abstract: In the field of eye tracking, greater accuracy or resolution in monitoring movement of the eye can be gained by digitizing the eye, and tracking the movement of a landmark with fixed size and a fixed location relative to the eye's local coordinate system. The edge of the iris can be used as such a fixed landmark. Through the location and or establishment of at least a portion of the outer edge of the iris and/or an iris center point, both large and small scale eye movements, including but not limited to micro-tremors, can be traced with a higher degree of accuracy. This will aid in the diagnosis of diseases, assessing state of consciousness, and defining brainstem death.

Abstract: A portable virtual reality device is disclosed that will facilitate the effective and efficient screening for TBI in military personnel in forward deployed military settings or remote locations using minimally trained staff. This includes the establishment of a protocol that will provide cost effective pre-screening of military personnel prior to deployment to establish a baseline of brain function prior to possible future injury. The efficiency of the device will promote subsequent follow-up screening to assess the effectiveness of prescribed TBI treatment. Further protocols for diagnosis and rehabilitation applications using the same virtual reality portable device will allow more advanced usage for clinicians providing ongoing evaluation and treatment.

Abstract: A system and associated methods are provided for intelligent placement and movement of orders in an electronic trading environment. According to one example method, in addition to submitting a leg order at a calculated price level, additional orders, queue holder orders, are submitted for the leg order at prices either below or above the calculated price level. Based on this configuration, if the conditions change such that it is necessary to re-price the leg order, there will be already an order resting in the exchange order book at the re-calculated price that can be used in the strategy. Upon re-pricing the leg order, one or more additional queue holder orders will be placed in the market. Other tools are provided as well.

Abstract: According to some embodiments, a set of images may be determined, including at least one training image and at least one image to be provided to a viewer. A reduced training image may be created based on the training image, and at least one enlarging parameter may be calculated based on a portion of the training image and a corresponding portion of the reduced training image. The enlarging parameter may then be used to facilitate an enlargement of a reduced image to be provided to the viewer.

Abstract: Viral upper respiratory tract infections, upper respiratory infections, and common colds can be effectively treated by the administration of a combination of a nasal steroid and a nasal antihistamine. By the administration of the combination of a nasal steroid and a nasal antihistamine with the onset of cold symptoms, the histamine cascade and the inflammatory response are impeded or eliminated, reducing the severity, duration, or frequency of the onset of cold symptoms. The combination of a nasal steroid and a nasal antihistamine may be, for example, a physical mixture of the steroid and antihistamine, or it may effectively be a combination wherein the patient is administered one component (either the steroid or the antihistamine) followed by the other, without physical mixing beforehand.

Abstract: A system and method for simulating the electrical operation of a mixed analog/digital system includes the capability for analog circuit block inputs to respond to the condition in which digital gate outputs connected to the analog circuit block input are presented in high-impedance or floating signal states, thereby providing for simulation of a wide variety of mixed analog/digital designs in which this condition occurs. In a simulated design, an analog input of one or more analog circuit blocks is transformed into an analog tri-statable input-output referred to as an ioput. The ioput is capable of driving an analog signal when the digital gate outputs connected to the analog block input are presented in a high-impedance Z state; otherwise, the ioput acts as an analog input to the analog circuit block.

Abstract: A system and associated methods are provided for intelligent placement and movement of orders in an electronic trading environment. According to one example method, in addition to submitting a leg order at a calculated price level, additional orders, queue holder orders, are submitted for the leg order at prices either below or above the calculated price level. Based on this configuration, if the conditions change such that it is necessary to re-price the leg order, there will be already an order resting in the exchange order book at the re-calculated price that can be used in the strategy. Upon re-pricing the leg order, one or more additional queue holder orders will be placed in the market. Other tools are provided as well.

Abstract: A method of sorting beads on a droplet actuator.

Abstract: In one embodiment, a material comprises a crystal comprising strontium iodide providing at least 50,000 photons per MeV. A scintillator radiation detector according to another embodiment includes a scintillator optic comprising europium-doped strontium iodide providing at least 50,000 photons per MeV. A scintillator radiation detector in yet another embodiment includes a scintillator optic comprising SrI2 and BaI2, wherein a ratio of SrI2 to BaI2 is in a range of between 0:1 A method for manufacturing a crystal suitable for use in a scintillator includes mixing strontium iodide-containing crystals with a source of Eu2+, heating the mixture above a melting point of the strontium iodide-containing crystals, and cooling the heated mixture near the seed crystal for growing a crystal. Additional materials, systems, and methods are presented.

Abstract: A goggle based light-weight VOG system includes at least one digital camera connected to and powered by a laptop computer through a firewire connection and allows for high speed pupil dilation tracking. An EOG system may be incorporated directly into a goggle base. The digital camera may digitally center the pupil in both the X and Y directions. A calibration mechanism may be incorporated onto the goggle base. The VOG system may track and record head position and goggle slippage. An animated eye display may provide data in a more meaningful fashion. The VOG system may be a modular design whereby the same goggle frame or base is used to build a variety of digital camera VOG systems.