Patents by Inventor An C. Wu

An C. Wu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Circuit-based optoelectronic tweezers
    Patent number: 9895699
    Abstract: A microfluidic optoelectronic tweezers (OET) device can comprise dielectrophoresis (DEP) electrodes that can be activated and deactivated by controlling a beam of light directed onto photosensitive elements that are disposed in locations that are spaced apart from the DEP electrodes. The photosensitive elements can be photodiodes, which can switch the switch mechanisms that connect the DEP electrodes to a power electrode between an off state and an on state.
    Type: Grant
    Filed: July 11, 2016
    Date of Patent: February 20, 2018
    Assignee: Berkeley Lights, Inc.
    Inventors: Steven W. Short, Ming C. Wu
  • Telescopic suitcase handle
    Patent number: 9894971
    Abstract: A telescopic suitcase handle is provided for including a telescopic handle housing disposed within a suitcase, a lower extendible handle section movably disposed within the telescopic handle housing, and an upper extendible handle section movably disposed within the lower section. A spring loaded bullet disposed within the upper section releasably engages with one of a plurality of openings along the length of the lower section for temporarily holding the upper extendible handle section in place. A spring-loaded protrusion releasably engages with the lower extendible handle section for temporarily holding the lower section in place.
    Type: Grant
    Filed: July 1, 2016
    Date of Patent: February 20, 2018
    Assignee: TUMI, INC.
    Inventors: Paul V. Scicluna, Peter C. Wu, Victor G. Sanz
  • Nucleic acids encoding synthetic scaffolds and host cells genetically modified with the nucleic acids
    Patent number: 9856460
    Abstract: The present invention provides methods of producing a product or product precursor of a biosynthetic pathway in a genetically modified host cell. The present invention also provides genetically modified host cells comprising nucleic acids encoding a scaffold polypeptide and nucleic acids comprising nucleotide sequences encoding two or more enzymes in a biosynthetic pathway. The present invention further provides nucleic acids comprising nucleotide sequences encoding scaffold polypeptides, for use in a subject method.
    Type: Grant
    Filed: June 25, 2014
    Date of Patent: January 2, 2018
    Assignee: The Regents of the University of California
    Inventors: John E. Dueber, Jay D. Keasling, Gabriel C. Wu, Ghulam Reza K. Malmirchegini
  • Pens for biological micro-objects
    Patent number: 9857333
    Abstract: Individual biological micro-objects can be deterministically selected and moved into holding pens in a micro-fluidic device. A flow of a first liquid medium can be provided to the pens. Physical pens can be structured to impede a direct flow of the first medium into a second medium in the pens while allowing diffusive mixing of the first medium and the second medium. Virtual pens can allow a common flow of medium to multiple ones of the pens.
    Type: Grant
    Filed: October 22, 2013
    Date of Patent: January 2, 2018
    Assignee: Berkeley Lights, Inc.
    Inventors: Kevin T. Chapman, Igor Y. Khandros, Gaetan L. Mathieu, J. Tanner Nevill, Ming C. Wu
  • Context driven memory circuits
    Patent number: 9858006
    Abstract: A memory device can be used with a shared routing resource that provides access to the memory device. The memory device can include a random access memory (RAM) circuit that includes a plurality of ports configured to provide access to the RAM circuit by the shared routing resource. A memory partition register circuit can be configured to store a plurality of addresses specifying respective context partitions within the RAM circuit. A plurality of pointer register circuits that can each be associated with a corresponding port of the plurality of ports and can be configured to store a respective set of pointers that specify a location in the RAM circuit relative to a respective context partition. Addressing logic that can be configured to provide access to the RAM circuit using the respective set of pointers for each port.
    Type: Grant
    Filed: October 13, 2015
    Date of Patent: January 2, 2018
    Assignee: XILINX, INC.
    Inventor: Ephrem C. Wu
  • Fabrication of a flexible circuit board
    Patent number: 9839136
    Abstract: The present disclosure relates, according to some embodiments, to the fabrication of a flexible circuit board, which includes forming a base layer comprising polyimide, forming a polyimide layer on the base layer, the polyimide layer having a first surface and a second surface opposite to each other, the first surface being peelably adhered in contact with the base layer, forming a metal layer on the second surface of the polyimide layer, and peeling the base layer from the polyimide layer with the metal layer remaining on the second surface of the polyimide layer.
    Type: Grant
    Filed: August 29, 2016
    Date of Patent: December 5, 2017
    Assignee: Taimide Technology Incorporation
    Inventors: Paul S. C. Wu, Chun-Ting Lai, Yen-Po Huang, Sheng-Yu Huang
  • Tensor operations and acceleration
    Patent number: 9779786
    Abstract: A system includes global memory circuitry configured to store input tensors and output tensors. Row data paths are each connected to an output port of the memory circuitry. Column data paths are connected to an input port of the memory circuitry. Processing elements are arranged in rows and columns along the row data paths and column data paths, respectively. The processing elements include local memory circuitry configured to store multiple masks and processing circuitry. The processing circuitry is configured to receive portions of the input tensors from one of the row data paths; receive masks from the local memory circuitry; perform multiple tensor operations on a same received portion of an input tensors by applying a different retrieved mask for each tensor operation; and generate, using results of the multiple tensor operations, an output for a corresponding column data path.
    Type: Grant
    Filed: October 26, 2016
    Date of Patent: October 3, 2017
    Assignee: XILINX, INC.
    Inventors: Ephrem C. Wu, Inkeun Cho, Xiaoqian Zhang
  • Opioid and opioid-like compounds and uses thereof
    Patent number: 9776971
    Abstract: The present invention relates to opioid and opioid-like compounds, and pharmaceutical formulations thereof, and use thereof for prevention and treatment of disorders such as septic shock and organ damage.
    Type: Grant
    Filed: September 9, 2011
    Date of Patent: October 3, 2017
    Assignee: TaiwanJ Pharmaceuticals Co., Ltd.
    Inventors: Edwin S. C. Wu, Mao-Hsiung Yen, Chin-Tsai Fan
  • Toll-like receptor 4 antagonists and use in autoimmune liver diseases
    Patent number: 9757372
    Abstract: The present invention relates to new medical uses of morphinans such as naltrexone, nalmefene and their related derivatives. The present invention relates to Toll-like receptor 4 (TLR4) antagonist compounds, and pharmaceutical formulations thereof, and use thereof for prevention and treatment of autoimmune liver diseases including but not limited to autoimmune hepatitis.
    Type: Grant
    Filed: March 23, 2016
    Date of Patent: September 12, 2017
    Assignee: TaiwanJ Pharmaceuticals Co., Ltd.
    Inventors: Peter J S Chiu, Mei-chi Hsu, Ying-Chu Shih, Edwin S C Wu
  • CYCLOPROPANECARBOXYLIC ACID GPR120 MODULATORS
    Publication number: 20170253554
    Abstract: The present invention provides compounds of Formula (I): or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the variables are as defined herein.
    Type: Application
    Filed: September 8, 2015
    Publication date: September 7, 2017
    Inventors: Yan Shi, Peter T.W. Cheng, Ying Wang, Sutjano Jusuf, Shiwei Tao, Hao Zhang, Shung C. Wu, Jeffrey A. Robl
  • CYCLOBUTANE CONTAINING CARBOXYLIC ACID GPR120 MODULATORS
    Publication number: 20170247311
    Abstract: The present invention provides compounds of Formula (I): or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the variables are as defined herein. These compounds are GPR120 G protein-coupled receptor modulators which may be used as medicaments.
    Type: Application
    Filed: September 8, 2015
    Publication date: August 31, 2017
    Inventors: Yan Shi, Ying Wang, Peter T.W. Cheng, Shung C. Wu
  • PHARMACEUTICAL COMPOSITIONS AND METHODS FOR COUNTERING CHEMOTHERAPY INDUCED CARDIOTOXICITY
    Publication number: 20170224654
    Abstract: This disclosure provides methods and pharmaceutical compositions for reducing or eliminating cardiotoxicity, particularly cardiotoxicity induced by a cancer treatment or other therapy. In some cases, the methods and compositions prevent or reduce cardiotoxicity caused by anthracycline treatment. The methods provided herein often comprise administering a protective agent such as myricetin, tricetin, robinetin, ficetin, vitexin, quercetin, dihydrorobinetin, kaempferol, 7,3?,4?,5?-tetrahydroxyflavone, and myricitrin in conjunction with the administration of a cancer drug or other treatment. They may comprise administering a protective agent in combination with dexrazoxane. The compositions provided herein include co-formulations of a protective agent with a different protective agent or with a cancer treatment (e.g., anthracycline drug).
    Type: Application
    Filed: February 3, 2017
    Publication date: August 10, 2017
    Applicants: Stem Cell Theranostics, Inc., Capella Biosciences, Inc.
    Inventors: Christopher G. Armstrong, Kevin J. Kim, Lisa Maria Lucia Pham, Eunhye Park, Zhong Zhong, Guanyi Huang, Joseph C. Wu, Sidney Paul Elmer, Viwat Visuthikraisee, Eithon Michael G Cadag, Thomas Bernard Freeman, Pek Yee Lum
  • Power control over memory cell arrays
    Patent number: 9666266
    Abstract: In disclosed circuit arrangements, memory cell arrays are addressed by a first portion of an input address, and memory cells within each memory cell array are addressed by a second portion of the input address. A first first-in-first-out (FIFO) buffer is coupled to the memory cell arrays and delays the second portion of each input address to the memory cell arrays for a sleep period. Control circuits respectively coupled to the memory cell arrays include second FIFO buffers and decode the first portion of each input address and generate corresponding states of enable signals. The control circuits store the corresponding states of the enable signals in the second FIFO buffers concurrently with input of the second portion of each input address to the first FIFO buffer. The second FIFO buffers delay output of the corresponding states of the enable signals to the memory cell arrays for the sleep period.
    Type: Grant
    Filed: May 9, 2016
    Date of Patent: May 30, 2017
    Assignee: XILINX, INC.
    Inventors: Hongbin Ji, Ephrem C. Wu, Thomas H. Strader
  • Strap connector and methods thereof
    Patent number: 9661911
    Abstract: A strap connector for connecting a strap to an article is provided that may comprise a t-bar for attaching the strap to the article, a housing for receiving the t-bar, the housing secured to the article, the housing comprising a floor, and a bumper plate for maintaining the t-bar in a position within the housing, the bumper plate comprising a bumper protruding above the surface of the floor of the housing.
    Type: Grant
    Filed: June 24, 2013
    Date of Patent: May 30, 2017
    Assignee: TUMI, INC.
    Inventors: Peter C. Wu, Paul V. Scicluna
  • Digital closed-loop control for DC/DC switch-mode power converters with multiple outputs
    Patent number: 9660538
    Abstract: Apparatus and method for providing closed loop feedback control for switch-mode DC/DC power converter with multiple outputs using digital filter feedback, in contrast to analog error feedback. In the apparatus and method, multiple outputs for a switch-mode DC/DC power converter are regulated by digital means, including the allocating or partitioning of digital control resources among each of the multiple outputs. The partitioning of control resources may be in response to operating conditions.
    Type: Grant
    Filed: May 6, 2015
    Date of Patent: May 23, 2017
    Assignee: SWITCHING POWER, INC.
    Inventor: Keng C. Wu
  • COMPOSITIONS AND METHODS FOR RENDERING TUMOR CELLS SUSCEPTIBLE TO CD8+ T CELL-MEDIATED KILLING
    Publication number: 20170137493
    Abstract: The present invention provides an immunoconjugate having the formula: T-c-En-c-Fcn or T-c-Fcn-c-En; wherein, T is a single chain variable portion fragment of a monoclonal antibody (scFv) directed to a target protein, polypeptide, or fragment thereof, which is highly expressed on cancer cells; E is two or more foreign immunogenic CD8+ T cell antigenic epitopes; c is a peptide or polypeptide fragment thereof, capable of being cleaved by a specific protease; and Fc is two or more Fc portions of an IgG antibody. Nucleic acid sequences encoding the same and vectors containing said nucleic acid sequences are also provided. Methods of making the immunoconjugate, along with methods of making target cells susceptible to CTL mediated cell killing, and methods for treatment of cancers are also provided.
    Type: Application
    Filed: January 11, 2017
    Publication date: May 18, 2017
    Inventors: Chien-Fu Hung, T.C. Wu
  • FABRICATION OF A FLEXIBLE CIRCUIT BOARD
    Publication number: 20170064838
    Abstract: The present disclosure relates, according to some embodiments, to the fabrication of a flexible circuit board, which includes forming a base layer comprising polyimide, forming a polyimide layer on the base layer, the polyimide layer having a first surface and a second surface opposite to each other, the first surface being peelably adhered in contact with the base layer, forming a metal layer on the second surface of the polyimide layer, and peeling the base layer from the polyimide layer with the metal layer remaining on the second surface of the polyimide layer.
    Type: Application
    Filed: August 29, 2016
    Publication date: March 2, 2017
    Inventors: Paul S.C. Wu, Chun-Ting Lai, Yen-Po Huang, Sheng-Yu Huang
  • DEP FORCE CONTROL AND ELECTROWETTING CONTROL IN DIFFERENT SECTIONS OF THE SAME MICROFLUIDIC APPARATUS
    Publication number: 20170043343
    Abstract: A microfluidic apparatus can comprise a dielectrophoresis (DEP) configured section for holding a first liquid medium and selectively inducing net DEP forces in the first liquid medium. The microfluidic apparatus can also comprise an electrowetting (EW) configured section for holding a second liquid medium on an electrowetting surface and selectively changing an effective wetting property of the electrowetting surface. The DEP configured section can be utilized to select and move a micro-object in the first liquid medium. The EW configured section can be utilized to pull a droplet of the first liquid medium into the second liquid medium.
    Type: Application
    Filed: April 25, 2015
    Publication date: February 16, 2017
    Inventors: Igor Y. KHANDROS, J. Tanner NEVILL, Steven W. SHORT, Ming C. WU
  • Suitcase
    Patent number: D780451
    Type: Grant
    Filed: May 13, 2015
    Date of Patent: March 7, 2017
    Assignee: TUMI, INC.
    Inventor: Peter C. Wu
  • Backpack
    Patent number: D802295
    Type: Grant
    Filed: May 14, 2015
    Date of Patent: November 14, 2017
    Assignee: TUMI, INC.
    Inventor: Peter C. Wu