Patents by Inventor Andreas Keller

Andreas Keller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20130245958
    Abstract: A method is disclosed for validation of single nucleotide variants (SNV) in a sequence of interest. In at least one embodiment, the method includes: interrogating a BAM-file of the sequence of interest and a reference sequence file and producing a summary table for genomic coordinates of interest; generating a plurality of sequence reads from a sample of said sequence of interest; filtering sequence reads using a plurality of filter levels; extracting SNV counts for each strand for a genomic region of interest within the sequence of interest, resulting in ten SNV counts; for each genomic region of interest determining a rule based genotype decision and inferring a best genotype from the 10 counts; and creating a single consensus file for said sequence of interest including information of best genotype and a best quality for each genomic region of interest.
    Type: Application
    Filed: March 12, 2013
    Publication date: September 19, 2013
    Applicant: Siemens Aktiengesellschaft
    Inventors: Michael FORSTER, Andre FRANKE, Andreas KELLER
  • Patent number: 8492579
    Abstract: The present invention relates to an improved method for producing all-E astaxanthin dimethyldisuccinate of the formula I.
    Type: Grant
    Filed: February 4, 2011
    Date of Patent: July 23, 2013
    Assignee: BASF SE
    Inventors: Hansgeorg Ernst, Walter Dobler, Andreas Keller, Klaus Henrich
  • Publication number: 20130157883
    Abstract: The present invention relates to single polynucleotides or sets of polynucleotides for detecting single miRNAs or sets of miRNAs for diagnosing and/or prognosing of an acute coronary syndrome in a blood sample from a human. Further, the present invention relates to means for diagnosing and/or prognosing of an acute coronary syndrome comprising said polynucleotides or sets of polynucleotides. Furthermore, the present invention relates to a method for diagnosing and/or prognosing of an acute coronary syndrome based on the determination of expression profiles of single miRNAs or sets of miRNAs representative for an acute coronary syndrome compared to a reference. In addition, the present invention relates to a kit for diagnosing and/or prognosing of an acute coronary syndrome comprising means for determining expression profiles of single miRNAs or sets of miRNAs representative for an acute coronary syndrome and at least one reference.
    Type: Application
    Filed: April 19, 2011
    Publication date: June 20, 2013
    Applicant: FEBIT HOLDING GMBH
    Inventors: Andreas Keller, Peer F. Stähler, Markus Beier, Benjamin Meder, Hugo A. Katus, Wolfgang Rottbauer
  • Patent number: 8461363
    Abstract: The invention relates to a process for the preparation of deodorized and stabilized food-grade marine oils by submitting marine oils to a counter-current steam distillation (CCSD) in a thin film column containing a structured packing and, if desired, adding antioxidant(s), to the food-grade marine oils thus obtained and to their uses in the food/feed, cosmetic and/or pharmaceutical industry.
    Type: Grant
    Filed: May 9, 2008
    Date of Patent: June 11, 2013
    Assignee: DSM IP Assets B.V.
    Inventors: Andreas Keller, Ingo Koschinski, Albert Lustenberger, Neil MacFarlane, Thomas Meierhans
  • Publication number: 20130102007
    Abstract: The present invention relates to the characterization of odorant receptors. In particular, the present invention relates to the OR7D4 proteins and nucleic acids encoding OR7D4 proteins and cell systems for screening for modulators of OR7D4 receptors. The present invention further provides assays for the detection of OR7D4 polymorphisms and mutations associated with altered olfactory sensation states, as well as methods of screening for therapeutic agents, ligands, and modulators of OR7D4 receptors.
    Type: Application
    Filed: October 29, 2012
    Publication date: April 25, 2013
    Inventors: Hiroaki Matsunami, Andreas Keller, Hanyi Zhuang, Qiuyi Chi, Leslie B. Vosshall
  • Publication number: 20130072726
    Abstract: A process for preparing 4-cyclohexyl-2-methyl-2-butanol, comprising: a) reaction of styrene with isopropanol at elevated temperature to obtain 2-methyl-4-phenyl-2-butanol, and b) heterogeneously catalyzed hydrogenation of 2-methyl-4-phenyl-2-butanol over a catalyst suitable for ring hydrogenation of aromatics, where the molar ratio of the styrene used in step a) to the isopropanol used in step a) is in the range from 1:below 5 to 1:0.5.
    Type: Application
    Filed: September 14, 2012
    Publication date: March 21, 2013
    Applicant: BASF SE
    Inventors: Rudolf Schuch, Stefan Rüdenauer, Klaus Ebel, Ralf Pelzer, Andreas Keller
  • Publication number: 20130053263
    Abstract: MicroRNAs (miRNA) are a recently discovered class of small non-coding RNAs (17-14 nucleotides). Due to their function as regulators of gene expression they play a critical role both in physiological and in pathological processes, such as cancer. The present invention provides novel methods for diagnosing a state of health based on the determination of specific miRNAs that have altered expression levels in different conditions, e.g. disease states compared to healthy controls.
    Type: Application
    Filed: December 30, 2010
    Publication date: February 28, 2013
    Applicant: FEBIT HOLDING GMBH
    Inventors: Andreas Keller, Eckart Meese, Anne Borries, Markus Beier
  • Publication number: 20130053264
    Abstract: MicroRNAs (miRNA) are a recently discovered class of small non-coding RNAs (17-14 nucleotides). Due to their function as regulators of gene expression they play a critical role both in physiological and in pathological processes, such as cancer. The present invention provides novel methods for diagnosing a state of health based on the determination of specific miRNAs that have altered expression levels in different conditions, e.g. disease states compared to healthy controls.
    Type: Application
    Filed: December 30, 2010
    Publication date: February 28, 2013
    Applicant: FEBIT HOLDING GMBH
    Inventors: Andreas Keller, Eckart Meese, Anne Borries, Markus Beier
  • Publication number: 20130035251
    Abstract: MicroRNAs (miRNA) are a recently discovered class of small non-coding RNAs (17-14 nucleotides). Due to their function as regulators of gene expression they play a critical role both in physiological and in pathological processes, such as cancer. The present invention provides novel methods for diagnosing a state of health based on the determination of specific miRNAs that have altered expression levels in different conditions, e.g. disease states compared to healthy controls.
    Type: Application
    Filed: December 30, 2010
    Publication date: February 7, 2013
    Applicant: febit holding GmbH
    Inventors: Andreas Keller, Eckart Meese, Anne Borries, Markus Beier
  • Publication number: 20120313404
    Abstract: A folding table for attachment to the rear side of a vehicle seat part has a fastening device (2a, 2c) for fastening the folding table to the vehicle seat (1a, 1b, 1c), a carrier element (4) which is connected to the fastening device (2a, 2c) and extends downward from the fastening device (2a, 2c) and a tabletop (6) rotatably connected to the carrier element (4). Supporting elements (7e) are arranged on the tabletop (6) which, when the tabletop (6) is in the working position, can be moved in the direction toward the vehicle seat part (1a, 1b, 1c) by a common actuating member (7a, 7d, 7b?, 7b?) and can be fixed in different positions by a manually releasable latching device (6h, 7b, 7c), so that the tabletop (6) can be aligned in a horizontal position.
    Type: Application
    Filed: December 6, 2010
    Publication date: December 13, 2012
    Inventors: Peter Ackeret, Michael Andreas Keller
  • Publication number: 20120309645
    Abstract: The present invention provides novel methods for diagnosing a state of health based on the determination of specific miRNAs that have altered expression levels in different conditions, e.g. disease states compared to healthy controls.
    Type: Application
    Filed: February 7, 2011
    Publication date: December 6, 2012
    Applicant: FEBIT HOLDING GMBH
    Inventors: Andreas Keller, Matthias Scheffler, Markus Beier
  • Patent number: 8298781
    Abstract: The present invention relates to the characterization of odorant receptors. In particular, the present invention relates to the OR7D4 proteins and nucleic acids encoding OR7D4 proteins and cell systems for screening for modulators of OR7D4 receptors. The present invention further provides assays for the detection of OR7D4 polymorphisms and mutations associated with altered olfactory sensation states, as well as methods of screening for therapeutic agents, ligands, and modulators of OR7D4 receptors.
    Type: Grant
    Filed: May 8, 2008
    Date of Patent: October 30, 2012
    Assignees: Duke University, The Rockefeller University
    Inventors: Hiroaki Matsunami, Andreas Keller, Hanyi Zhuang, Qiuyi Chi, Leslie B. Vosshall
  • Publication number: 20120157336
    Abstract: The present invention provides novel methods for diagnosing a state of health based on the determination of specific miRNAs that have altered expression levels in different conditions, e.g. disease states compared to healthy controls.
    Type: Application
    Filed: June 7, 2010
    Publication date: June 21, 2012
    Applicant: FEBIT HOLDING GMBH
    Inventors: Andreas Keller, Eckart Meese, Anne Borries, Peer Friedrich Staehler, Markus Beier
  • Publication number: 20120157337
    Abstract: The present invention provides novel methods for diagnosing diseases based on the determination of specific miR-NAs that have altered expression levels in disease states compared to healthy controls.
    Type: Application
    Filed: June 7, 2010
    Publication date: June 21, 2012
    Applicant: FEBIT HOLDING GMBH
    Inventors: Andreas Keller, Eckart Meese, Anne Borries, Peer Friedrich Staehler, Markus Beier
  • Publication number: 20120108462
    Abstract: The present invention provides novel methods for diagnosing diseases based on the determination of specific miRNAs that have altered expression levels in disease states compared to healthy controls.
    Type: Application
    Filed: June 7, 2010
    Publication date: May 3, 2012
    Applicant: FEBIT HOLDING GMBH
    Inventors: Andreas Keller, Eckart Meese, Anne Borries, Markus Beier
  • Publication number: 20120045771
    Abstract: The invention relates to a method for isolation of target molecules from a nucleic acid population.
    Type: Application
    Filed: December 11, 2009
    Publication date: February 23, 2012
    Applicant: FEBIT HOLDING GMBH
    Inventors: Markus Beier, Peer F. Staehler, Cord F. Staehler, Daniel Summerer, Jack T. Leonard, Stephan Bau, Anthony Caruso, Nadine Schracke, Andreas Keller, Helmut Hanenberg, Olaf Eckermann
  • Publication number: 20120004498
    Abstract: The present invention relates to a sensory device for reducing tension in a subject. The device includes an elastic covering, a filling material inside the elastic covering, an openable sealed reservoir located within the filling, an absorbent material surrounding the reservoir, and a calming odor releasing substance sealed within the reservoir. The present invention also relates to a method of reducing tension in a subject. This method involves providing a subject in need of tension relief with the device of the present invention. The device is manipulated to break open the reservoir and release the calming odor releasing substance. The released calming odor is inhaled in an amount sufficient to lower salivary cortisol levels in the subject and thereby reduce tension in the subject.
    Type: Application
    Filed: June 16, 2011
    Publication date: January 5, 2012
    Applicant: NEW YORK UNIVERSITY
    Inventors: Dolores MALASPINA, Andreas KELLER, Daniel ANTONIUS
  • Publication number: 20110237840
    Abstract: The invention relates to a process for preparing potassium and potassium compounds
    Type: Application
    Filed: March 25, 2011
    Publication date: September 29, 2011
    Applicant: BASF SE
    Inventors: Hagen Wilmer, Andreas Keller
  • Publication number: 20110196170
    Abstract: The present invention relates to an improved method for producing all-E astaxanthin dimethyldisuccinate of the formula I.
    Type: Application
    Filed: February 4, 2011
    Publication date: August 11, 2011
    Applicant: BASF SE
    Inventors: HANSGEORG ERNST, Walter Dobler, Andreas Keller, Klaus Henrich
  • Patent number: D669524
    Type: Grant
    Filed: April 1, 2011
    Date of Patent: October 23, 2012
    Assignee: Dacarbo AG
    Inventor: Andreas Keller