Patents by Inventor Andreas Keller

Andreas Keller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20160311741
    Abstract: A process for preparing 4-cyclohexyl-2-methyl-2-butanol, comprising: a) reaction of styrene with isopropanol at elevated temperature to obtain 2-methyl-4-phenyl-2-butanol, and b) heterogeneously catalyzed hydrogenation of 2-methyl-4-phenyl-2-butanol over a catalyst suitable for ring hydrogenation of aromatics, where the molar ratio of the styrene used in step a) to the isopropanol used in step a) is in the range from 1:below 5 to 1:0.5.
    Type: Application
    Filed: June 29, 2016
    Publication date: October 27, 2016
    Inventors: RUDOLF SCHUCH, Stefan Rüdenauer, Klaus Ebel, Ralf Pelzer, Andreas Keller
  • Publication number: 20160273040
    Abstract: The invention relates to methods for diagnosing Alzheimer's Disease (AD) with miRNA markers. Diagnosis of AD Towards the identification of biomarkers for diagnosis of AD, a comprehensive analysis of miRNA expression patterns was obtained. Significantly deregulated miRNAs were identified.
    Type: Application
    Filed: October 29, 2013
    Publication date: September 22, 2016
    Inventors: Andreas KELLER, Cord Friedrich STÄHLER, Eckart MEESE, Andreas KAPPEL, Christina BACKES, Petra LEIDINGER
  • Patent number: 9416079
    Abstract: A process for preparing 4-cyclohexyl-2-methyl-2-butanol, comprising: a) reaction of styrene with isopropanol at elevated temperature to obtain 2-methyl-4-phenyl-2-butanol, and b) heterogeneously catalyzed hydrogenation of 2-methyl-4-phenyl-2-butanol over a catalyst suitable for ring hydrogenation of aromatics, where the molar ratio of the styrene used in step a) to the isopropanol used in step a) is in the range from 1:below 5 to 1:0.5.
    Type: Grant
    Filed: May 12, 2015
    Date of Patent: August 16, 2016
    Assignee: BASF SE
    Inventors: Rudolf Schuch, Stefan Rüdenauer, Klaus Ebel, Ralf Pelzer, Andreas Keller
  • Publication number: 20160162635
    Abstract: The invention relates to a method, a databank, a system and a computer program product for determining a bacterial resistance to an antibiotic drug. A data bank is provided which comprises a plurality of bacterial reference nucleic acid sequences, wherein at least some reference nucleic acid sequences are associated with a respective antibiotic drug resistance information. A comparison unit is used for comparing said bacterial nucleic acid sequence information obtained from a sample with said plurality of bacterial reference nucleic acid sequences.
    Type: Application
    Filed: June 25, 2014
    Publication date: June 9, 2016
    Applicant: Siemens Aktiengesellschaft
    Inventors: Andreas KELLER, Cord Friedrich STÄHLER, Gabriel RENSEN
  • Publication number: 20160159505
    Abstract: Various embodiments of the present disclosure are directed to a mobile strapping device for wrapping material to be packed with a strap, the device comprising: a tensioning unit for applying a strap tension to a loop of a strap, a welding unit for producing a welded connection on two superimposed regions of the strap loop, a housing with a front housing region formed as a cover for the tensioning unit and a rear housing region for receiving a rechargeable energy store, and a handle arranged between the front and the rear housing regions for holding the strapping device. The aim of the invention is to improve the assembly and repair properties. To achieve this object, a module is proposed which comprises the display and operating apparatus and at least parts of the controller of the strapping device.
    Type: Application
    Filed: May 5, 2014
    Publication date: June 9, 2016
    Inventors: Roland Widmer, Andreas Keller
  • Publication number: 20160138117
    Abstract: Described herein are non-invasive methods, kits and means for diagnosing and/or prognosing of colon cancer a body fluid sample from a subject. Further described herein are sets of polynucleotides or sets of primer pairs for detecting sets of miRNAs for diagnosing and/or prognosing of colon cancer in a body fluid sample from a subject. In addition, described herein are sets of miRNAs for diagnosing and/or prognosing of colon cancer in a body fluid sample from a subject.
    Type: Application
    Filed: January 21, 2016
    Publication date: May 19, 2016
    Applicant: Comprehensive Biomarker Center GmbH
    Inventors: Andreas Keller, Markus Beier, Eckart Meese, Petra Leidinger, Anke Wendschlag
  • Patent number: 9320688
    Abstract: The present invention relates to improved powderous formulations of organic acids or esters having an aromatic ring system, as well as to the production of such formulations.
    Type: Grant
    Filed: February 6, 2013
    Date of Patent: April 26, 2016
    Assignee: DSM IP ASSETS B.V.
    Inventors: Martin Gadient, Thomas Lindemann, Karl Manfred Voelker, Kai Urban, Stefanie Kirchen, Andreas Keller
  • Publication number: 20160107775
    Abstract: Various embodiments of the present disclosure are directed to a mobile strapping device for wrapping material to be packed with a strap. The device includes a tensioning wheel and a tensioning plate, at least one of which is mounted on a pivotable rocker. The strapping device includes a motor operatively coupleable to the tensioning wheel to rotate the tensioning wheel and to the rocker to pivot the rocker. The strapping device includes an actuating device actuatable to switch the state of gearing from operatively coupling the motor to the tensioning wheel to operatively coupling the motor to the rocker.
    Type: Application
    Filed: May 5, 2014
    Publication date: April 21, 2016
    Applicant: Orgapack GmbH
    Inventors: Pascal Amacker, Andreas Keller
  • Publication number: 20160076103
    Abstract: The present invention provides novel methods for diagnosing a state of health based on the determination of specific miRNAs that have altered expression levels in different conditions, e.g. disease states compared to healthy controls.
    Type: Application
    Filed: September 28, 2015
    Publication date: March 17, 2016
    Inventors: Andreas KELLER, Eckart MEESE, Anne BORRIES, Peer Friedrich STAEHLER, Markus BEIER
  • Publication number: 20160053325
    Abstract: The present invention provides novel methods for diagnosing diseases based on the determination of specific miRNAs that have altered expression levels in disease states compared to healthy controls.
    Type: Application
    Filed: October 2, 2015
    Publication date: February 25, 2016
    Applicant: COMPREHENSIVE BIOMARKER CENTER GMBH
    Inventors: Andreas KELLER, Eckart MEESE, Anne BORRIES, Peer Friedrich STAEHLER, Markus BEIER
  • Patent number: 9249469
    Abstract: The present invention relates to non-invasive methods, kits and means for diagnosing and/or prognosing of colon cancer in a body fluid sample from a subject. Further, the present invention relates to set of polynucleotides or sets of primer pairs for detecting sets of miRNAs for diagnosing and/or prognosing of colon cancer in a body fluid sample from a subject. In addition, the present invention relates to sets of miRNAs for diagnosing and/or prognosing of colon cancer in a body fluid sample from a subject.
    Type: Grant
    Filed: August 3, 2012
    Date of Patent: February 2, 2016
    Assignee: Comprehensive Biomarker Center GmbH
    Inventors: Andreas Keller, Markus Beier, Eckart Meese, Petra Leidinger, Anke Wendschlag
  • Publication number: 20150337393
    Abstract: MicroRNAs (miRNA) are a recently discovered class of small non-coding RNAs (17-14 nucleotides). Due to their function as regulators of gene expression they play a critical role both in physiological and in pathological processes, such as cancer. The present invention provides novel methods for diagnosing prostate cancer based on the determination of specific miRNAs that have altered expression levels in different conditions, e.g.
    Type: Application
    Filed: August 11, 2015
    Publication date: November 26, 2015
    Applicant: COMPREHENSIVE BIOMARKER CENTER GMBH
    Inventors: Andreas KELLER, Eckart MEESE, Anne BORRIES, Markus BEIER
  • Patent number: 9194002
    Abstract: The present invention provides novel methods for diagnosing a state of health based on the determination of specific miRNAs that have altered expression levels in different conditions, e.g. disease states compared to healthy controls.
    Type: Grant
    Filed: June 7, 2010
    Date of Patent: November 24, 2015
    Assignee: Comprehensive Biomarker Center GmbH
    Inventors: Andreas Keller, Eckart Meese, Anne Borries, Peer Friedrich Staehler, Markus Beier
  • Patent number: 9187785
    Abstract: The present invention provides novel methods for diagnosing diseases based on the determination of specific miRNAs that have altered expression levels in disease states compared to healthy controls.
    Type: Grant
    Filed: June 7, 2010
    Date of Patent: November 17, 2015
    Assignee: Comprehensive Biomarker Center GmbH
    Inventors: Andreas Keller, Eckart Meese, Anne Borries, Peer Friedrich Staehler, Markus Beier
  • Publication number: 20150315641
    Abstract: The invention relates to methods for diagnosing Parkinson's Disease PAD) with miRNA markers. Towards the identification of biomarkers for diagnosis of PD, a comprehensive analysis of miRNA expression patterns was obtained. Significantly deregulated miRNAs were identified.
    Type: Application
    Filed: July 26, 2013
    Publication date: November 5, 2015
    Inventors: Andreas KELLER, Cord Friedrich STÄHLER, Jan KIRSTEN, Eckart MEESE, Christina BACKES, Petra LEIDINGER
  • Publication number: 20150292020
    Abstract: MicroRNAs (miRNA) are a recently discovered class of small non-coding RNAs (17-14 nucleotides). Due to their function as regulators of gene expression they play a critical role both in physiological and in pathological processes, such as cancer. The present invention provides novel methods for diagnosing a state of health based on the determination of specific miRNAs that have altered expression levels in different conditions, e.g. disease states compared to healthy controls.
    Type: Application
    Filed: June 30, 2015
    Publication date: October 15, 2015
    Applicant: COMPREHENSIVE BIOMARKER CENTER GMBH
    Inventors: Andreas Keller, Eckart Meese, Anne Borries, Markus Beier
  • Publication number: 20150292013
    Abstract: The invention relates to novel miRNA markers useful for diagnosis or therapy of disease, in particular for neuronal disorders such as Alzheimer's Disease (AD).
    Type: Application
    Filed: November 4, 2013
    Publication date: October 15, 2015
    Inventors: Andreas Keller, Cord Friedrich Stähler, Christina Backes, Eckart Meese, Petra Leidinger, Andreas Kappel
  • Publication number: 20150246864
    Abstract: A process for preparing 4-cyclohexyl-2-methyl-2-butanol, comprising: a) reaction of styrene with isopropanol at elevated temperature to obtain 2-methyl-4-phenyl-2-butanol, and b) heterogeneously catalyzed hydrogenation of 2-methyl-4-phenyl-2-butanol over a catalyst suitable for ring hydrogenation of aromatics, where the molar ratio of the styrene used in step a) to the isopropanol used in step a) is in the range from 1:below 5 to 1:0.5.
    Type: Application
    Filed: May 12, 2015
    Publication date: September 3, 2015
    Inventors: Rudolf Schuch, Stefan Rüdenauer, Klaus Ebel, Ralf Pelzer, Andreas Keller
  • Patent number: 9073826
    Abstract: A process for preparing salts of acrylamido-2-methylpropanesulfonic acid (A) using the steps of: preparing a solution of a contaminated salt of acrylamido-2-methyl-propanesulfonic acid (A) in an anhydrous organic solvent (L) using at least one basic component (B) selected from the group of alkali metal oxides, alkaline earth metal oxides, alkali metal hydroxides, alkaline earth metal hydroxides and amines of the formula (I) NRaRbRc??(I) where the Ra, Rb and Rc radicals are each independently: hydrogen, C1-C4-alkyl, hydroxy-C1-C4-alkyl or C1-C4-alkoxy, where the molar ratio of compound (A) to the basic component (B) is 1:1 to 1:3, recovering the dissolved salt of compound (A) by crystallization or by precipitation, by altering the temperature and/or the pressure and/or the concentration of the salt in the solution. This leads to salts which are low in by-products and are particularly suitable for polymerization.
    Type: Grant
    Filed: November 28, 2012
    Date of Patent: July 7, 2015
    Assignee: BASF SE
    Inventors: Klaus Ebel, Tobias Voitl, Andreas Keller, Stefan Rüdenauer, Karsten Bartling, Bjorn Langlotz, Jochen Steiner
  • Publication number: 20150184223
    Abstract: The invention relates to a method and kit for enriching miRNA nucleic acids molecules of interest in a sampe by selective removal of nucleic acid species, in particular miRNA species, which are not of interest. The invention is based on the surprizing and previously unknown information that only a few individual miRNA species make up the majority of all miRNA species in a sample. Selective removal of these species prior to detection of miRNA nucleic acids molecules will improve assay time, assay sensitivity, and reproducibility.
    Type: Application
    Filed: June 26, 2013
    Publication date: July 2, 2015
    Applicants: SIEMENS HEALTHCARE DIAGNOSTICS HOLDING GMBH, SIEMENS AKTIENGESELLSCHAFT
    Inventors: Andreas Keller, Andreas Kappel, Cord Friedrich Stähler