Abstract: An apparatus for dynamically adjusting a journal snapshot window is disclosed. A computer-implemented method and computer program product also perform the functions of the apparatus. According to an embodiment of the present invention, a failure detection module detects a potential failure of at least a portion of a non-volatile storage device. The non-volatile storage device includes a journal for tracking metadata changes for data that is stored on the non-volatile storage device prior to committing the metadata changes to metadata for the non-volatile storage device. A notification receiving module receives an indication of the potential failure of the non-volatile storage device. A snapshot module adjusts a snapshot window for the journal in response to the indication of the potential failure. The snapshot window includes a set of metadata changes in the journal that have not been committed to the metadata of the non-volatile storage device.

Abstract: A method, computer program product and computer system are are provided. A processor receives a host input/output write operation, wherein the host input/output write operation includes host metadata regarding data represented by the host input/output write operation. The processor stores the host input/output write operation in one or more physical storage data units. A processor assigns a priority to the one or more physical storage data units. In response to receiving a host volume delete command associated with at least one of the one or more physical storage data units, a processor prioritizes data units of the host volume for deletion based, at least in part, on the assigned priority of the data units of the host volume, wherein data units with a lower priority are permanently deleted before data units with a higher priority.

Abstract: Storing data volumes in virtual and physical address spaces such that the data units are contiguous in virtual address space but fragmented in physical address space. The mapping between virtual and physical address space is managed by a storage controller that is configured to implement deletes reversibly with a so-called soft delete, the soft delete being reversible up to a later permanent or hard delete. A soft delete triggers a compaction in which the data units of the to-be-deleted volume are gathered together in physical address space. During the time between compaction and hard delete (or restore), the soft deleted volume is thus stored in a space efficient manner. Moreover, the subsequent hard delete can be performed more quickly than if the soft deleted volume were still fragmented across physical address space freeing up space quicker.

Abstract: The invention provides carbazole derivatives for the treatment of fibrotic diseases (pathological collagen deposition) in tissues and organs, and related symptoms, and conditions thereof.

Abstract: Storing data volumes in virtual and physical address spaces such that the data units are contiguous in virtual address space but fragmented in physical address space. The mapping between virtual and physical address space is managed by a storage controller that is configured to implement deletes reversibly with a so-called soft delete, the soft delete being reversible up to a later permanent or hard delete. A soft delete triggers a compaction in which the data units of the to-be-deleted volume are gathered together in physical address space. During the time between compaction and hard delete (or restore), the soft deleted volume is thus stored in a space efficient manner. Moreover, the subsequent hard delete can be performed more quickly than if the soft deleted volume were still fragmented across physical address space freeing up space quicker.

Abstract: Concepts for storing a data block in a plurality of at least three storage units forming a RAID drive array are presented. The RAID drive array operates using a log-structured filing system. Dividing the data block into at least two sets of data sub-blocks and generating check data for the at least two sets of data sub-blocks, the check data enabling the reconstruction of one of the sets of data sub-blocks using the other set or sets of data sub-blocks. Further storing each set of data sub-blocks and the check data in a different storage unit and obtaining location metadata that identifies a physical location for the data sub-blocks within the storage unit in which the respective data sub-blocks are stored and storing a copy of the location metadata in at least two storage units.

Abstract: A method and a system are provided for controlling deduplication in a storage pool. The method includes creating one or more deduplication domains within a storage pool, wherein storage volumes that are within a deduplication domain are deduplicated only with other volumes within the same deduplication domain and assigning storage volumes to a deduplication domain in order to control deduplication between storage volumes. The method may include, within a deduplication domain, blocklisting a volume from deduplication with a specified volume whilst allowing deduplication with other volumes in the deduplication domain.

Abstract: The invention provides synergistic combinations of at least two modulators of MOR, as well as combined compositions, kits methods and uses thereof for treating mental and physical pain, suicidality and depression.

Abstract: The invention provides carbazole derivatives for the treatment of fibrotic diseases (pathological collagen deposition) in tissues and organs, and related symptoms, and conditions thereof.

Abstract: A data storage system comprises physical storage, cache memory and a processor connected to the physical storage and the cache memory. The processor is arranged to maintain a set of active regions in the cache memory, each active region having a size equal to an integer multiple of an update size of a flash chip within the physical storage, where the integer could be 1. The processor receives requests for one or more blocks of the cache memory from components within the storage system and allocates one or more blocks from an active region in response to a received request. If the processor determines that all blocks in an active region have been allocated and that all allocated blocks within this region have been written to, then the processor destages the content of this region to the physical storage.

Abstract: A processor may identify a storage system having a cluster of multiple nodes with redundancy for sharing a load of host input/output (IO) operations. The processor may upgrade one or more nodes at a time making use of redundancy. The processor may collect performance statistics of the storage system with the upgraded nodes during active use of the host IO operations. The processor may compare the collected performance statistics with historical performance statistics for the storage system. If the upgraded nodes show a negative performance impact, the processor may take remedial action. Otherwise, the processor may continue to upgrade the remaining nodes.

Abstract: A data storage system configured to deduplicate and store sets of data is presented. The system comprises a computer readable storage device configured to store a plurality of sets of data for a plurality of hosts, wherein each sets of data of the plurality of sets of data corresponding to each host of the plurality of hosts is encrypted with one or more different encryption keys, and wherein at least one of the plurality of sets of data contains deduplicated data. The system also comprises a key translator configured to create at least one translation key based, at least in part, on the one or more different encryption keys and the deduplicated data, and wherein the at least one translation key is configured to translate from a first encryption key to a second encryption key of the one or more different encryption keys.

Abstract: Aspects of the present invention disclose a method, computer program product, and system for stale data recovery using virtual storage metadata. The method includes one or more processors generating a primary virtual storage metadata structure having virtual address areas for a data chunk. Each area includes a plurality of most recent updates of metadata for the data chunk. The metadata of each update includes a sequence number for the update and a pointer to the physical location of the data. The method further includes one or more processors generating an overflow virtual storage metadata structure for multiple virtual address areas. The overflow metadata structure includes updates that have overflowed from the virtual address areas. In addition, wherein an oldest update in a full virtual address area of the primary virtual storage metadata structure includes a link to an overflow location.

Abstract: A method, computer system, and a computer program product for storing a write data in a storage system that operates using a log-structured filing system is provided. The present invention may include compressing a write data. The present invention may also include identifying a region of a storage system based on a first size of the compressed write data. The present invention may further include the storage system operating using a log-structured filing system. The present invention may also include a different region of the storage system having a different compression ratio. The present invention may further include writing the compressed write data in the identified region of the storage system.

Abstract: A computer-implemented method according to one embodiment includes receiving, by a target system from a source system, a description of a set of data updates that are to be written to the target system. For each given portion of data of the target system that is to be rewritten during performance of the set of data updates, forward lookup is performed on the target system for determining a physical storage address of the given portion of data. The method further includes marking each of the determined physical storage addresses of the portions of data of the target system in a copy of a reverse lookup table of the target system. The marked-up reverse lookup table is used for determining an ordering in which the performance of the set of data updates would result in a least amount of garbage collection being performed while performing the set of data updates.

Abstract: The present invention provides compounds and methods for the treatment and prevention of diseases and conditions associate with or aggravated by impaired mitophagy.

Abstract: Short peptides and peptidomimetics useful for treating Type 2 diabetes are provided, and methods for treating and/or preventing Type 2 diabetes and related conditions.

Abstract: Method and system are provided for storage handling guidance for host input/output (I/O) operations. The method includes: providing a guidance array of indications of storage operations handling instructions, the guidance array having multiple dimensions of performance characteristics with each dimension having multiple levels; and associating a reference vector with one or more I/O operations, wherein the reference vector points to a level for each dimension of the array to obtain an indication of a storage operations handling instruction at an intercept of the dimension levels for application by a storage system controller for the one or more I/O operations.

Abstract: Method and system are provided for data validation during data recovery in a log-structure array (LSA) storage system. The method includes reading a log record of a recovery log for a logical address to obtain a physical address at a storage backend for the data at the time of the log record; reading reference metadata at the obtained physical address, wherein the reference metadata indicates the logical address that last wrote data to the physical address; validating that the physical address for the log record contains valid data for the logical address of the log record by comparing the logical address of the reference metadata to the logical address of the log record; and replaying the log record if the physical address is validated for recovery of virtual domain logical metadata mapping the logical address to the physical addresses of the log record.

Abstract: An apparatus for dynamically adjusting a journal snapshot window is disclosed. A computer-implemented method and computer program product also perform the functions of the apparatus. According to an embodiment of the present invention, a failure detection module detects a potential failure of at least a portion of a non-volatile storage device. The non-volatile storage device includes a journal for tracking metadata changes for data that is stored on the non-volatile storage device prior to committing the metadata changes to metadata for the non-volatile storage device. A notification receiving module receives an indication of the potential failure of the non-volatile storage device. A snapshot module adjusts a snapshot window for the journal in response to the indication of the potential failure. The snapshot window includes a set of metadata changes in the journal that have not been committed to the metadata of the non-volatile storage device.