Abstract: For combining virtual mapping metadata and physical space mapping metadata in a storage system by a processor device in a computing environment, data and metadata are maintained into separate virtual streams. The separate virtual streams include a metadata stream for the metadata and a data stream for the data. Information of a mapping of logical data to a location on the data stream and a current state of unused spaces in the data stream is linearly distributed within the metadata stream.

Abstract: B-Tree data is serialized to existing data for all types of workloads. The serialized B-Tree data, that has been split, sorted and classified into identified data ranges, is then compressed.

Abstract: B-Tree data is serialized to existing data for all types of workloads by converting a B-Tree data structure into a format capable of being stored and resurrected while containing all data stored in the B-Tree data structure and information relating to the B-Tree data structure.

Abstract: This invention relates to novel penetrating compositions including one or more effectors included within a water soluble composition, immersed in a hydrophobic medium. The invention also relates to methods of treating or preventing diseases by administering such penetrating compositions to affected subjects.

Abstract: Calculating fingerprints for each one of a multiplicity of alignment combinations of fixed-size deduplication data blocks and comparing each of the fingerprints to stored deduplicated data fingerprints in a lookup database for determining a preferred deduplication data block alignment. A deduplication data block comprises each of the fixed-size deduplication data blocks.

Abstract: For serving sequential read patterns from a compressed journal storage system, a construction area cache algorithm is used to temporarily store the read and decompressed data in a user view sequential order to minimize disk I/Os and CPU utilization while serving the data to the user.

Abstract: For efficient serialization of journal data using a processor device, serialization is combined with journaling of data into one data storage system on a write operation with subsequent consolidation for serialization of the journal data.

Abstract: For efficiently storing and retrieving data and metadata in phases, in a first phase, metadata tokens, which are assigned to metadata-emitting entities, are used for storing the data and the metadata together in a single input/output operation while piggybacking the metadata of least active metadata-emitting entities onto one of the metadata-emitting entities having one of the metadata tokens. In a second phase, the metadata is re-written to a metadata delta journal for reclaiming the metadata tokens. In a third phase, the metadata journal is applied to a metadata structure containing the metadata of the storage system, the metadata delta journal is then cleared after successfully updating the main metadata structure with the metadata of the metadata journal. The metadata journal is swapped with an empty metadata journal for concurrently adding metadata while retaining the metadata journal until applying the metadata delta journal to the metadata structure.

Abstract: For combining virtual mapping metadata and physical space mapping metadata in a storage system by a processor device in a computing environment, data and metadata are maintained into separate virtual streams. The separate virtual streams include a metadata stream for the metadata and a data stream for the data. Information of a mapping of logical data to a location on the data stream and a current state of unused spaces in the data stream is linearly distributed within the metadata stream.

Abstract: B-Tree data is serialized to existing data for all types of workloads. The serialized B-Tree data, that has been split, sorted and classified into identified data ranges, is then compressed.

Abstract: B-Tree data is serialized to existing data for all types of workloads by converting a B-Tree data structure into a format capable of being stored and resurrected while containing all data stored in the B-Tree data structure and information relating to the B-Tree data structure.

Abstract: For efficiently storing and retrieving data and metadata in phases, in a first phase, metadata tokens, which are assigned to most active metadata-emitting entities, are used for storing the data and the metadata together in a single input/output operation while piggybacking the metadata of least active metadata-emitting entities onto one of the most active metadata-emitting entities having one of the metadata tokens. In a second phase, the metadata is re-written to a metadata delta journal for reclaiming the metadata tokens. In a third phase, the metadata journal is applied to a metadata structure containing the metadata of the storage system, the metadata delta journal is then cleared after successfully updating the main metadata structure with the metadata of the metadata journal. The metadata journal is swapped with an empty metadata journal for concurrently adding metadata while retaining the metadata journal until applying the metadata delta journal to the metadata structure.

Abstract: The present invention provides a combination comprising: a composition comprising at least one non-steroidal anti-inflammatory agent and at least one cytotoxic agent; and a composition comprising at least one ribonucleotide reductase inhibitor. The invention further includes kits comprising a combination of the invention and methods and uses of a combination of the invention for the treatment of cancer treatment of cancer, including solid tumors or tumor metastasis.

Abstract: Tricyclic compounds, compositions and uses thereof in the treatment of at least one disease, disorder or condition such as for example obesity, overweight, abnormal fat-distribution and any conditions or disease associated therewith.

Abstract: For efficiently storing and retrieving data and metadata in phases, in a first phase, metadata tokens, which are assigned to most active metadata-emitting entities, are used for storing the data and the metadata together in a single input/output operation while piggybacking the metadata of least active metadata-emitting entities onto one of the most active metadata-emitting entities having one of the metadata tokens. In a second phase, the metadata is re-written to a metadata delta journal for reclaiming the metadata tokens. In a third phase, the metadata journal is applied to a metadata structure containing the metadata of the storage system, the metadata delta journal is then cleared after successfully updating the main metadata structure with the metadata of the metadata journal. The metadata journal is swapped with an empty metadata journal for concurrently adding metadata while retaining the metadata journal until applying the metadata delta journal to the metadata structure.

Abstract: A data chunk is compressed into a storage block when emitting the data chunk. If the data chunk is unable to be completely compressed into the storage block, attributes of the data chunk are analyzed for determining whether the data chunk should be split. If the data chunk should be split, a remaining portion of the data chunk is compressed to a next chronological storage block. If the data chunk should not be split, all of the data chunk is moved to the next chronological storage block while leaving any remaining space in the storage block as unused.

Abstract: A data chunk is compressed into a storage block when emitting the data chunk. If the data chunk is unable to be completely compressed into the storage block, attributes of the data chunk are analyzed for determining whether the data chunk should be split. If the data chunk should be split, a remaining portion of the data chunk is compressed to a next chronological storage block. If the data chunk should not be split, all of the data chunk is moved to the next chronological storage block while leaving any remaining space in the storage block as unused.

Abstract: An electronic device (100) is presented, being configured for example as a vertical field effect transistor. The device comprises an electrically-conductive perforated patterned structure (102) which is enclosed between a dielectric layer (105) and an active element (106) of the electronic device (100). The electrically-conductive perforated patterned structure (102) comprises a geometrical pattern defining an array of spaced-apart perforation regions (108) surrounded by continuous electrically conductive regions (110). The pattern is such as to allow the active element (106) of the electronic device (100) to be in direct contact with said dielectric layer (105) aligned with the perforation regions (108). A material composition of the device (100) and features of said geometrical pattern are selected to provide a desired electrical conductance of the electrically-conductive perforated patterned structure (102) and a desired profile of a charge carriers' injection barrier along said structure (102).

Abstract: For efficiently storing and retrieving data and metadata in phases, in a first phase, metadata tokens, which are assigned to most active metadata-emitting entities, are used for storing the data and the metadata together in a single input/output operation while piggybacking the metadata of least active metadata-emitting entities onto one of the most active metadata-emitting entities having one of the metadata tokens. In a second phase, the metadata is re-written to a metadata delta journal for reclaiming the metadata tokens. In a third phase, the metadata journal is applied to a metadata structure containing the metadata of the storage system, the metadata delta journal is then cleared after successfully updating the main metadata structure with the metadata of the metadata journal. The metadata journal is swapped with an empty metadata journal for concurrently adding metadata while retaining the metadata journal until applying the metadata delta journal to the metadata structure.

Abstract: For efficiently storing and retrieving data and metadata in phases, in a first phase, metadata tokens, which are assigned to most active metadata-emitting entities, are used for storing the data and the metadata together in a single input/output operation while piggybacking the metadata of least active metadata-emitting entities onto one of the most active metadata-emitting entities having one of the metadata tokens. In a second phase, the metadata is re-written to a metadata delta journal for reclaiming the metadata tokens. In a third phase, the metadata journal is applied to a metadata structure containing the metadata of the storage system, the metadata delta journal is then cleared after successfully updating the main metadata structure with the metadata of the metadata journal. The metadata journal is swapped with an empty metadata journal for concurrently adding metadata while retaining the metadata journal until applying the metadata delta journal to the metadata structure.