Patents by Inventor Ben SASSON

Ben SASSON has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20040254116
    Abstract: The invention concerns a method for the modulation of tissue-remodeling processes, by contacting the tissue to be remodeled with a compound comprising a sequence derived from certain regions of TGF-&bgr; super family Ser/Thr/kinase receptors.
    Type: Application
    Filed: July 2, 2004
    Publication date: December 16, 2004
    Applicants: Children's Medical Center Corporation, Yissum Research and Development
    Inventor: Shmuel Ben-Sasson
  • Patent number: 6770626
    Abstract: The invention concerns a method for the modulation of tissue-remodeling processes, by contacting the tissue to be remodeled with a compound comprising a sequence derived from certain regions of TGF-&bgr; super family Ser/Thr/kinase receptors.
    Type: Grant
    Filed: December 31, 2001
    Date of Patent: August 3, 2004
    Assignees: Children's Medical Center Corporation, Yissum Research Development Company of the Hebrew University of Jerusalem
    Inventor: Shmuel Ben-Sasson
  • Publication number: 20040146549
    Abstract: This invention relates to novel pharmaceutical penetration compositions capable of facilitating penetration of at least one effector across biological barriers. The invention also relates to methods of treating or preventing diseases by administering penetration compositions to affected subjects.
    Type: Application
    Filed: September 17, 2003
    Publication date: July 29, 2004
    Inventors: Shmuel A. Ben-Sasson, Einat Cohen
  • Publication number: 20040121952
    Abstract: The present invention concerns methods for the treatment of solid tumors by the inhibition of Lyn associated signal transduction. Preferred in accordance with the invention are inhibitors which comprise sequences derived from specific regions of the Lyn. The present invention further concerns a method for the treatment of cancer by the administration of compounds comprising Lyn-derived peptides.
    Type: Application
    Filed: June 6, 2003
    Publication date: June 24, 2004
    Applicants: Children's Medical Center Corporation, Yissum Research and Development
    Inventors: Shmuel Ben-Sasson, Hadas Reuveni
  • Patent number: 6723830
    Abstract: Peptides which are peptide derivatives of the &agr;D region of a protein kinase can modulate the activity of protein kinases. The activity of a protein kinase in a subject can be modulated by administering one or more of these peptides.
    Type: Grant
    Filed: January 8, 2002
    Date of Patent: April 20, 2004
    Assignees: Children's Medical Center Corporation, Yissum Research and Development
    Inventor: Shmuel A. Ben-Sasson
  • Patent number: 6723694
    Abstract: Disclosed are peptides which are peptide derivatives of the HJ loop of a protein tyrosine kinase. The peptides can modulate the activity of the protein tyrosine kinase. Also disclosed are methods of modulating the activity of a protein tyrosine kinase in a subject by administering one of the peptides of the present invention.
    Type: Grant
    Filed: May 21, 1997
    Date of Patent: April 20, 2004
    Assignees: The Children's Medical Center Corp., Yissum Research Development Company of the Hebrew University of Jerusalem
    Inventor: Shmuel A. Ben-Sasson
  • Publication number: 20030211589
    Abstract: Peptides which are peptide derivatives of the B4-5 region of a protein kinase can modulate the activity of protein kinases. The activity of a protein kinase in a subject can be modulated by administering one or more of these peptides.
    Type: Application
    Filed: October 23, 2002
    Publication date: November 13, 2003
    Inventor: Shmuel Ben-Sasson
  • Patent number: 6513686
    Abstract: A water-supply pack assembly adapted to hitch onto the driver's seat in an automobile, thereby making it possible for the driver to drink water drawn from the supply without having to interrupt his driving activity The assembly includes a fixture attachable to the headrest of the driver's seat and a water-supply pack mountable on the fixture so that it is then behind the back of the seat. A flexible tube extending from the outlet of the supply and terminating in a valved mouthpiece functions as a straw to permit the driver with the mouthpiece in place to suck water from the supply as he drives the vehicle.
    Type: Grant
    Filed: August 30, 2000
    Date of Patent: February 4, 2003
    Inventor: Amit Ben-Sasson
  • Publication number: 20030004103
    Abstract: The present invention concerns methods for the treatment of metabolic-related diseases by the modulation of GRK associated signal transduction. Preferred in accordance with the invention are modulators which comprise sequences derived from specific regions of the GRK.
    Type: Application
    Filed: December 11, 2001
    Publication date: January 2, 2003
    Applicant: Children's Medical Center Corporation
    Inventor: Shmuel Ben-Sasson
  • Publication number: 20020167490
    Abstract: Disclosed is a method for replacing a remote unit in a communication system. The method includes the steps of determining that a removed remote unit has been removed from the communication system. The method also includes the step of determining that a new remote unit has been installed in the place of the removed remote unit. The steps of the method further include recalling parameters associated with the removed remote unit and providing the recalled parameters associated with the removed remote unit to the new remote unit.
    Type: Application
    Filed: January 10, 2002
    Publication date: November 14, 2002
    Inventors: Haim Weissman, Victor H. Ben-Sasson, Itsik Boger
  • Publication number: 20020165150
    Abstract: The invention concerns a method for the modulation of tissue-remodeling processes, by contacting the tissue to be remodeled with a compound comprising a sequence derived from certain regions of TGF-&bgr; super family Ser/Thr/kinase receptors.
    Type: Application
    Filed: December 31, 2001
    Publication date: November 7, 2002
    Applicant: Children's Medical Center Corporation
    Inventor: Shmuel Ben-Sasson
  • Publication number: 20020160478
    Abstract: Peptides which are peptide derivatives of the &agr;D region of a protein kinase can modulate the activity of protein kinases. The activity of a protein kinase in a subject can be modulated by administering one or more of these peptides.
    Type: Application
    Filed: January 8, 2002
    Publication date: October 31, 2002
    Applicant: Children's Medical Center Corporation
    Inventor: Shmuel A. Ben-Sasson
  • Publication number: 20020151497
    Abstract: The present invention concerns methods for the treatment of prostate cancer by the inhibition of Lyn-kinase associated signal transduction. Preferred in accordance with the invention are inhibitors which comprise sequences derived from specific regions of the Lyn-kinase.
    Type: Application
    Filed: December 11, 2001
    Publication date: October 17, 2002
    Applicant: Children's Medical Center Corporation
    Inventor: Shmuel Ben-Sasson
  • Publication number: 20020137141
    Abstract: The present invention concerns compounds comprising, within short sequences from a specific region of the kinase, that can modulate kinase-associated signal transduction.
    Type: Application
    Filed: December 11, 2001
    Publication date: September 26, 2002
    Applicant: Children's Medical Center Corporation
    Inventor: Shmuel Ben-Sasson
  • Publication number: 20020115173
    Abstract: Peptides which are peptide derivatives of the A region of a protein kinase can modulate the activity of protein kinases. The activity of a protein kinase in a subject can be modulated by administering one or more of these peptides.
    Type: Application
    Filed: December 11, 2000
    Publication date: August 22, 2002
    Applicant: Children's Medical Center Corporation
    Inventor: Shmuel A. Ben-Sasson
  • Publication number: 20020049301
    Abstract: Disclosed are peptides which are peptide derivatives of the HJ loop of a serine/threonine kinase. The peptides can modulate the activity of the serine/threonine kinase. Also disclosed are methods of modulating the activity of a serine/threonine kinase in a subject by administering one of the peptides of the present invention.
    Type: Application
    Filed: December 13, 2000
    Publication date: April 25, 2002
    Applicant: The Children's Medical Center Corp.
    Inventor: Shmuel A. Ben-Sasson
  • Publication number: 20020028772
    Abstract: Disclosed is a method for modulating metabolism in an individual. The method includes administering to the individual a substance, such as a GRK-derived HJ loop peptide, which alters activity of a GRK, wherein the administration of the substance results in an increase or decrease of the individual's metabolism. Also disclosed are GRK-derived HJ loop peptides.
    Type: Application
    Filed: December 11, 2000
    Publication date: March 7, 2002
    Applicant: Children's Med. Corporation,
    Inventor: Shmuel A. Ben-Sasson
  • Publication number: 20020019346
    Abstract: Prostate cancer can be treated by administering one or more inhibitros of lyn tyrosine kinase to an individual who has or is susceptible to contracting prostate cancer. The inhibitors include peptides containing between six and eleven amino acids.
    Type: Application
    Filed: December 11, 2000
    Publication date: February 14, 2002
    Applicant: Children's Medical Center Corporation
    Inventor: Shmuel A. Ben-Sasson
  • Patent number: 6235716
    Abstract: Disclosed are novel multivalent ligands represented by the following structural formula: B is a multilinker backbone. n is an integer from two to about twenty. Each L is a covalent bond or linking group. Each P is a peptide having from about 10 to about 30 amino acid residues. At least two of the peptides P are a peptide derivative of an AHR of an angiogenic protein, a hybrid peptide, a peptide derivative of a hybrid peptide or a combination thereof. Each peptide and each linker or covalent bond is independently chosen. The disclosed multivalent ligands can be used to modulate angiogenesis in a mammal. Also disclosed are novel peptide derivatives of an AHR of an angiogenic protein, novel hybrid peptides, peptide derivatives of the novel hybrid peptides and polypeptide multivalent ligands thereof.
    Type: Grant
    Filed: December 29, 1999
    Date of Patent: May 22, 2001
    Assignee: Children's Medical Center Corporation
    Inventor: Shmuel A. Ben-Sasson
  • Patent number: 6174993
    Abstract: Disclosed are peptides which are peptide derivatives of the HJ loop of a serine/threonine kinase. The peptides can modulate the activity of the serine/threonine kinase. Also disclosed are methods of modulating the activity of a serine/threonine kinase in a subject by administering one of the peptides of the present invention.
    Type: Grant
    Filed: May 21, 1997
    Date of Patent: January 16, 2001
    Assignees: The Children's Medical Center Corp., Yissum Research Development Company of the Hebrew University of Jerusalem
    Inventor: Shmuel A. Ben-Sasson