Patents by Inventor Ben SASSON

Ben SASSON has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20100071095
    Abstract: The present invention provides a method for the generation of genetically diverse plants via the incorporation of micro-satellite (MS) sequences into the planar genome. The method involves obtaining MS-like DNA fragment, introducing said DNA into plant cells, and selecting said cells for the incorporation of the DNA. Finally, plants are grown from the selected cells. Said plants display phenotypic variability, and are more diverse than the parental plant. Using the method herein presented, novel plant varieties are generated.
    Type: Application
    Filed: September 11, 2009
    Publication date: March 18, 2010
    Inventors: Iris Bahir, Shmuel Ben-Sasson
  • Publication number: 20090318391
    Abstract: The present invention relates to the treatment of a mammal with a pharmaceutical composition comprising an H2-blocker, at least one anti-inflammatory agent, a cytotoxic agent and, optionally, levamisole, a retinoid, an NFkB inhibitor, a redox quinone, an agent that enhances the intracellular accumulation of NADH+H+, a poly-alcohol, an inhibitor of pro-angiogenic growth factor(s) and an MMP inhibitor, such pharmaceutical composition allowing for the enhanced therapy and/or prevention of neoplastic diseases and disorders.
    Type: Application
    Filed: July 4, 2007
    Publication date: December 24, 2009
    Applicant: TILTAN PHARMA LTD.
    Inventor: Shmuel A. Ben-Sasson
  • Publication number: 20090010887
    Abstract: The present invention relates to the surprising discovery that agents that increase intracellular accumulation of NADH+H+ enhance the anti-cancer effects of angiogenesis inhibitors. Furthermore, treatment of a mammal with a combination of at least one angiogenesis inhibitor and at least one agent that enhances intracellular accumulation of NADH+H+ allows for the enhanced treatment and/or prevention of angiogenic diseases and disorders.
    Type: Application
    Filed: October 5, 2005
    Publication date: January 8, 2009
    Inventor: Shmuel A. Ben-Sasson
  • Publication number: 20080159984
    Abstract: This invention relates to novel penetrating compositions including one or more effectors included within a water soluble composition, immersed in a hydrophobic medium The invention also relates to methods of treating or preventing diseases by administering such penetrating compositions to affected subjects.
    Type: Application
    Filed: April 14, 2005
    Publication date: July 3, 2008
    Inventor: Shmuel A. Ben-Sasson
  • Publication number: 20080045460
    Abstract: The present invention concerns methods for the treatment of prostate cancer by the inhibition of Lyn-kinase associated signal transduction. Preferred in accordance with the invention are inhibitors which comprise sequences derived from specific regions of the Lyn-kinase.
    Type: Application
    Filed: December 21, 2006
    Publication date: February 21, 2008
    Applicants: CHILDREN'S MEDICAL CENTER CORPORATION, YISSUM RESEARCH AND DEVELOPMENT
    Inventor: Shmuel BEN-SASSON
  • Publication number: 20070275055
    Abstract: This invention relates to novel pharmaceutical compositions mixing one or more effectors (anionic impermeable molecules) with a counter ion to the effector (a liquid forming cation). The invention also relates to methods of treating or preventing diseases by administering pharmaceutical compositions to affected subjects.
    Type: Application
    Filed: July 16, 2007
    Publication date: November 29, 2007
    Inventors: Shmuel Ben-Sasson, Einat Cohen
  • Publication number: 20070219131
    Abstract: This invention relates to novel penetrating compositions including one or more effectors included within a water soluble composition, immersed in a hydrophobic medium. The invention also relates to methods of treating or preventing diseases by administering such penetrating compositions to affected subjects.
    Type: Application
    Filed: October 20, 2006
    Publication date: September 20, 2007
    Inventor: Shmuel Ben-Sasson
  • Publication number: 20070172517
    Abstract: This invention relates to novel pharmaceutical compositions capable of facilitating penetration of at least one effector across biological barriers. The invention also relates to methods of treating or preventing diseases by administering these compositions to affected subjects.
    Type: Application
    Filed: September 17, 2004
    Publication date: July 26, 2007
    Inventors: Shmuel Ben-Sasson, Einat Galamidi-Cohen
  • Publication number: 20060265775
    Abstract: The present invention provides a method for the generation of genetically diverse plants via the incorporation of micro-satellite (MS) sequences into the plant genome. The method involves obtaining MS-like DNA fragment, introducing said DNA into plant cells, and selecting said cells for the incorporation of the DNA. Finally, plants are grown from the selected cells. Said plants display phenotypic variability, and are more diverse than the parental plant. Using the method herein presented, novel plant varieties are generated.
    Type: Application
    Filed: March 25, 2004
    Publication date: November 23, 2006
    Inventors: Iris Bahir, Shmuel Ben-Sasson
  • Publication number: 20060257869
    Abstract: The present invention concerns compounds comprising, within short sequences from a specific regions of the 7TM receptor, that can modulate 7TM receptor-associated signal. The present invention further concerns methods for stimulation angiogenesis by administration of peptides derived from the EDG3 7TM-receptor.
    Type: Application
    Filed: September 3, 2003
    Publication date: November 16, 2006
    Applicant: Children's Hospital
    Inventors: Shmuel Ben-Sasson, Hadas Reuveni
  • Publication number: 20060251713
    Abstract: This invention relates to novel pharmaceutical penetration compositions capable of facilitating penetration of at least one effector across biological barriers. The invention also relates to methods of treating or preventing diseases by administering penetration compositions to affected subjects.
    Type: Application
    Filed: July 18, 2006
    Publication date: November 9, 2006
    Applicant: Chiasma, Inc.
    Inventors: Shmuel Ben-Sasson, Einat Cohen
  • Patent number: 7115707
    Abstract: This invention relates to novel pharmaceutical penetration compositions capable of facilitating penetration of at least one effector across biological barriers. The invention also relates to methods of treating or preventing diseases by administering penetration compositions to affected subjects.
    Type: Grant
    Filed: September 17, 2003
    Date of Patent: October 3, 2006
    Assignee: Chiasma, Inc.
    Inventors: Shmuel A. Ben-Sasson, Einat Cohen
  • Patent number: 7037891
    Abstract: The present invention concerns methods for the treatment of metabolic-related diseases by the modulation of GRK associated signal transduction. Preferred in accordance with the invention are modulators which comprise sequences derived from specific regions of the GRK.
    Type: Grant
    Filed: December 11, 2001
    Date of Patent: May 2, 2006
    Assignees: Children's Medical Center Corporation, Yissum Research and Development
    Inventor: Shmuel Ben-Sasson
  • Publication number: 20050232981
    Abstract: This invention relates to novel penetrating compositions including one or more effectors included within a water soluble composition, immersed in a hydrophobic medium. The invention also relates to methods of treating or preventing diseases by administering such penetrating compositions to affected subjects.
    Type: Application
    Filed: April 14, 2005
    Publication date: October 20, 2005
    Inventor: Shmuel Ben-Sasson
  • Publication number: 20050215478
    Abstract: The invention relates to amino acid sequences capable of facilitating penetration of an effector across a biological barrier. The invention also relates to methods of treating preventing diseases by administering or penetrating modules to affected subjects.
    Type: Application
    Filed: February 7, 2003
    Publication date: September 29, 2005
    Inventors: Shmuel Ben-Sasson, Einat Cohen
  • Publication number: 20050148521
    Abstract: The present invention relates to the surprising discovery that the combination of several agents, each well known for its established role in treating cancer, inflammation, hemostasis, bone resorption or serving as a solubilizing vehicle, results in a synergistic anti-cancer composition. Furthermore, the combination of at least three agents allows the cytotoxic agent, such as cyclophosphamide, to be used at a lower dosage than when administered alone. One predicted consequence of this treatment, therefore, is a highly desirable reduction in toxic side effects due to the cytotoxic agent.
    Type: Application
    Filed: July 23, 2004
    Publication date: July 7, 2005
    Applicants: Yissum Research Development Company of the Hebrew University, The Children's Medical Center Corporation
    Inventors: Shmuel Ben-Sasson, Lilia Tsirulnikov, Vladimir Vainstein
  • Publication number: 20050136103
    Abstract: This invention relates to novel pharmaceutical compositions capable of facilitating penetration of at least one effector across biological barriers. The invention also relates to methods of treating or preventing diseases by administering these compositions to affected subjects.
    Type: Application
    Filed: September 16, 2004
    Publication date: June 23, 2005
    Inventors: Shmuel Ben-Sasson, Einat Cohen
  • Publication number: 20050058702
    Abstract: This invention relates to novel pharmaceutical compositions mixing one or more effectors (anionic impermeable molecules) with a counter ion to the effector (a liquid forming cation). The invention also relates to methods of treating or preventing diseases by administering pharmaceutical compositions to affected subjects.
    Type: Application
    Filed: September 17, 2003
    Publication date: March 17, 2005
    Inventors: Shmuel Ben-Sasson, Einat Cohen
  • Patent number: 6833436
    Abstract: Disclosed are peptides which are peptide derivatives of the HJ loop of a serine/threonine kinase. The peptides can modulate the activity of the serine/threonine kinase. Also disclosed are methods of modulating the activity of a serine/threonine kinase in a subject by administering one of the peptides of the present invention.
    Type: Grant
    Filed: December 13, 2000
    Date of Patent: December 21, 2004
    Assignees: Children's Medical Center Corporation, Yissum Research Development Company of the Hebrew University of Jerusalem
    Inventor: Shmuel A. Ben-Sasson
  • Patent number: D597736
    Type: Grant
    Filed: November 8, 2007
    Date of Patent: August 11, 2009
    Inventor: Amit Ben-Sasson