Abstract: A component for a gas turbine engine according to an exemplary embodiment of the present disclosure can include a substrate, a thermal barrier coating deposited on at least a portion of the substrate, and an outer layer deposited on at least a portion of the thermal barrier coating. The outer layer can include a material that is reactive with an environmental contaminant that comes into contact with the outer layer to alter a microstructure of the outer layer.

Abstract: A method is disclosed for pressure forming a metal preform including shock annealing of the preform and subsequently preheating the preform prior to pressure forming. Shock annealing may be carried out as differential shock annealing in which different regions of the preform are annealed to different degrees. Preheating may be carried out by differentially preheating, optionally shock preheating, different regions of the preform for preheating at least those regions of the preform which will be subject to elevated expansion during pressure forming. Shock annealing by induction heating can lower energy consumption, reduce processing times and allow for larger expansion of the preform.

Abstract: A system for assessing potential cybersecurity threats to a subject system is provided. The system includes a computer system including at least one processor in communication with at least one memory device. The at least one processor is programmed to: receive a subject system to analyze, determine a potential hazard event associated with the subject system, generate an attack graph associated with the potential hazard event, wherein the attack graph includes a plurality of actions, determine an exploitability score for each of the plurality of actions, determine an uncertainty level for each of the plurality of actions based on the corresponding exploitability score, aggregate the plurality of actions including the corresponding exploitability scores and the corresponding uncertainty levels to determine one or more vulnerabilities of the subject system, and generate a response to the one or more vulnerabilities of the subject system.

Abstract: Described herein are systems and methods for determining or quantifying tinnitus conditions within a patient, including determining if a patient has some form of tinnitus as well as categorizing or determining the severity of a tinnitus condition, if present. The described systems and methods are also useful in evaluating the efficacy a tinnitus treatment by measuring the degree of reduction of tinnitus symptoms in a patient. The described systems and methods also provide a personalized profile for each specific patient, allowing for more effective treatment options as various forms or causes of tinnitus become apparent.

Abstract: A beverage-ingredient cartridge for storing and dispensing beverage ingredients. The cartridge includes a container for storing a first beverage ingredient, and a cap secured within an open upper end of the container that seals the open upper end. The cap includes a storage compartment for storing a second beverage ingredient having a base and a sidewall extending from a the base. A line of weakness defines a separable region of the base, and a column extends from the separable region of the base and is spaced apart from the sidewall. A plastic film is secured to the sidewall and to the column that seals the storage compartment. Upon application of a force to the column, the separable region separates from the base and the plastic film tears such that the storage compartment and container are open to the outside of the beverage-ingredient cartridge.

Abstract: An energy storage system is disclosed. The energy storage system includes at least one energy store, a power convertor for converting between a DC voltage present at the at least one energy store and an AC voltage, a transformer for transforming between the AC voltage and a line voltage of an energy supply network, and a control device for controlling the energy storage system. The transformer is switchable for setting a transformation ratio for converting between the AC voltage and the line voltage, wherein the control device is configured to set the transformation ratio of the transformer depending on the DC voltage present at the at least one energy store.

Abstract: A method to reconstruct an environment is provided. The method makes available to a wide variety of XR applications fresh and accurate 3D reconstruction data of environments with low processing time and low usage of computational resources and storage spaces. The 3D reconstruction data are structured in a way to be efficiently shared between users for multi-user experiences. The method includes obtaining plane segments of an environment, identifying surface planes of the environment by, for example, filtering and grouping the plane segments or ad hoc selection of the plane segments by a user, and inferring corner points of the environment based on the surface planes. The corner points are used to build a 3D representation of the environment when an XR application requires.

Abstract: A deep neural network (DNN) media noise predictor configured for one-dimensional-magnetic (1DMR) recording or two-dimensional-magnetic (TDMR) is introduced. Such architectures are often combined with a trellis-based intersymbol interference (ISI) detection component in a turbo architecture to avoid the state explosion problem by separating the inter-symbol interference (ISI) detection and media noise estimation into two separate detectors and uses the turbo-principle to exchange information between them so as to address the modeling problem by way of training a DNN-based media noise estimators. Thus, beneficial aspects include a reduced bit-error rate (BER), an increased areal density, and a reduction in computational complexity and computational time.

Abstract: Methods and systems for the secure delivery and processing of exam questions and responses. One or more exam questions and one or more identifiers of one or more designated individuals who are authorized to print the one or more exam questions are transported using a secure protocol. Biometric information is obtained from an individual requesting to print the one or more exam questions and information is read from an embedded tag that identifies a corresponding exam sheet as a unique exam sheet for a specified exam and that identifies that the specified exam is for a particular student. The specified exam is printed on the unique exam sheet in response to a first current time being in a printing time window TW1 and the biometric information from the individual matching biometric information of one of the one or more designated individuals.

Abstract: The invention relates to prodrug compounds of formula I: wherein R2, R3, R5, R7 and X are as defined herein. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders, including pain. The compounds of formula I possess advantageous solubility and physicochemical properties.

Abstract: Aircraft, aircraft wings and associated shear ties are disclosed. An example apparatus includes a first panel coupled to a second panel to define a wing box; a rib disposed chordwise within the wing box; and a stringer disposed spanwise within the wing box immediately adjacent at least one of the first panel or the second panel, the rib including a shear tie including first and second legs extending in opposite directions, the first and second legs to be coupled to at least one of the first panel, the second panel, or the stringer.

Abstract: The present invention relates to processes and intermediates for preparing compounds useful as inhibitors of ATR kinase, such as aminopyrazine-isoxazole derivatives and related molecules. The present invention also relates to compounds useful as inhibitors of ATR protein kinase. The invention relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and solid forms of the compounds of this invention.

Abstract: Disclosed is a mobile device vehicle apparatus comprising a housing portion having a wiring harness and a shelf portion having an inclined surface and lip, the lip extending away from the inclined surface, wherein the housing portion or the shelf portion further comprising a wireless data transmission module, a wiring harness, and a wireless charger; and wherein the wireless charger is provided behind the inclined surface of the shelf portion.

Abstract: The invention relates to prodrug compounds of formula I: wherein R2, R3, R5, R7 and X are as defined herein. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders, including pain. The compounds of formula I possess advantageous solubility and physicochemical properties.

Abstract: Aircraft, aircraft wings and associated shear ties are disclosed. An example apparatus includes a first panel coupled to a second panel to define a wing box; a rib disposed chordwise within the wing box; and a stringer disposed spanwise within the wing box immediately adjacent at least one of the first panel or the second panel, the rib including a shear tie including first and second legs extending in opposite directions, the first and second legs to be coupled to at least one of the first panel, the second panel, or the stringer.

Abstract: Systems and methods for eye tracking calibration in a wearable system are described. The wearable system can present three-dimensional (3D) virtual content and allow a user to interact with the 3D virtual content using eye gaze. During an eye tracking calibration, the wearable system can validate that a user is indeed looking at a calibration target while the eye tracking data is acquired. The validation may be performed based on data associated with the user's head pose and vestibulo-ocular reflex.

Abstract: Compositions containing a nucleic acid nanostructure having a desired geometric shape and antigens bound to its surface are provided. The nanostructures can be, for example, in the form of a 6-helix bundle or icosahedron. The nanostructure design allows for control of the relative position and/or stoichiometry of the antigen bound to its surface. The antigens displayed on the nanostructure surface are arranged with the preferred number, spacing, and 3D organization to elicit a robust immune response. The displayed antigen can be an HIV immunogen such as eOD-GT6, eOD-GT8, or variants thereof. The compositions may thus be useful as immunogens, vaccines, immunostimulators, adjuvants, and the like. Methods of inducing immune responses, inducing protective immunity, inducing the production of neutralizing antibodies or inhibitory antibodies, inducing tolerance, and treating cancer, infectious or autoimmune diseases are also provided.

Abstract: A beverage ingredient cartridge for releasing beverage ingredients into a bottle to create a mixed beverage includes a body defining a liquid-ingredient chamber, a cap defining a solid-ingredient chamber, and an opening mechanism disposed on the cap. Upon a force applied to the beverage ingredient cartridge, a piercer of the bottle drives through the dispensing end of the cartridge, causing teeth of the opening mechanism to tear through films sealing the liquid-ingredient chamber and solid-ingredient chamber. This mixes contents of the liquid-ingredient chamber with contents of the solid-ingredient chamber and releases the mixed contents from the beverage ingredient cartridge into a bottle below that is filled with a liquid, creating a mixed beverage.