Abstract: Embodiments disclosed herein provide an organic matter processing apparatus and method for the use thereof to convert organic matter into a ground and desiccated product. This can be accomplished using a bucket assembly that can grind, paddle, and heat organic matter contained therein. An algorithm is used to control the conversion of organic input to organic output by progressing through processing states based, in part, on time windows, runtimes, and sensor inputs.

Abstract: Embodiments disclosed herein provide an organic matter processing apparatus and method for the use thereof to convert organic matter into a ground and desiccated product. The organic matter processing apparatus includes a lid assembly that is positioned at the top or head of the processing apparatus and an air treatment system. The lid assembly is operative to open to allow a user to deposit organic matter into the processing apparatus or to remove a removable bucket contained therein. The lid assembly is operative to close and provide an odor containing seal that prevents or substantially mitigates escape of odor. The air treatment system uniformly distributes untreated air through an air treatment chamber to convert the untreated air to treated air, which is exhausted out of the processing apparatus.

Abstract: This disclosure relates to compounds of formula (I), which are modulators of STING. Also disclosed are pharmaceutical compositions comprising compounds of formula (I) and methods of using compounds of formula (I) in the treatment or prevention of diseases ameliorated by the modulation of STING.

Abstract: An engine oil lubrication system includes an oil flow control baffle disposed in the sump of the oil pan. The baffle may be detachably mountable in the sump of the oil pan. The baffle may be configured to prevent oil returning to the sump from the engine from short-circuiting and flowing directly to the oil pump intake. The baffle creates a circuitous flow path which forces mixing of the returning oil before being drawn into the oil pump intake nozzle via increasing resonance time of the oil in the sump to enhance cooling. The present disclosure further provides a modular engine mounting system which extends the number of engines and vehicle chassis which can utilize a single oil pan to mount to the chassis. Interchangeable mounting flanges are provided having different bolting patterns compatible with the different chassis.

Abstract: The present disclosure relates to engineered T cells and methods of making and using the same, as well as reagents for making the engineered T cells.

Abstract: A method to reconstruct an environment is provided. The method makes available to a wide variety of XR applications fresh and accurate 3D reconstruction data of environments with low processing time and low usage of computational resources and storage spaces. The 3D reconstruction data are structured in a way to be efficiently shared between users for multi-user experiences. The method includes obtaining plane segments of an environment, identifying surface planes of the environment by, for example, filtering and grouping the plane segments or ad hoc selection of the plane segments by a user, and inferring corner points of the environment based on the surface planes. The corner points are used to build a 3D representation of the environment when an XR application requires.

Abstract: An image-guided robotic intervention system (“IGRIS”) may be used to perform medical procedures on patients. IGRIS provides a real-time view of patient anatomy, as well as an intended target or targets for the procedures, software that allows a user to plan an approach or trajectory path using either the image or the robotic device, software that allows a user to convert a series of 2D images into a 3D volume, and localizes the 3D volume with respect to real-time images during the procedure. IGRIS may include sensors to estimate pose of the imaging device relative to the patient to improve the performance of that software with respect to runtime, robustness, and accuracy.

Abstract: An articulating cannula assembly is described. The articulating cannula assembly includes: a hand piece; a proximal housing situated above the hand piece; a cannula distally extending from the proximal housing, the cannula including an articulating segment; and a trigger that, when actuated, extends or contracts the articulating segment. The proximal housing can removably couple to the hand piece. The proximal housing can include an endoscope attachment structure for removably securing a proximal portion of an endoscope.

Abstract: A compound of formula (I): wherein: Y is (CH2)n, where n is from 2 to 4; W1 and W11 are independently selected from OH and ORP, where RP is Me or Et.

Abstract: A compound of formula (I); wherein: W is O or NH; A1 is CRA or N; A2 is CRB or N; A3 is CRC or N; A4 is CRD or N; where no more than two of A1, A2, A3, and A4 may be N; one or two of RA, RB, RC and RD, (if present) are selected from H, F, Cl, Br, Me, CF3, cyclopropyl, cyano, OMe, OEt, CH2OH, CH2OMe and OH; the remainder of R A, RB, RC and RD, (if present) are H; RN1 is H or Me; one of RC2 and RC3 is C(?O)NH2; the other is selected from H, Cl, F, Br, Me, OMe, OEt, cyano, CF3, CH2OH, CH2OMe, C2-4 alkenyl and C5heterocyclyl; RC1 and RC4 are independently selected from H, Cl, F, Br, Me, OMe, OEt, cyano, CF3, CH2OH, CH2OMe, C2-4 alkenyl and C5heterocyclyl.

Abstract: A method to reconstruct an environment is provided. The method makes available to a wide variety of XR applications fresh and accurate 3D reconstruction data of environments with low processing time and low usage of computational resources and storage spaces. The 3D reconstruction data are structured in a way to be efficiently shared between users for multi-user experiences. The method includes obtaining plane segments of an environment, identifying surface planes of the environment by, for example, filtering and grouping the plane segments or ad hoc selection of the plane segments by a user, and inferring corner points of the environment based on the surface planes. The corner points are used to build a 3D representation of the environment when an XR application requires.

Abstract: A hollow preform impact extruded from a metal billet to produce a progressing wall at a transition wall thickness. An axially forward portion of the progressing wall is ironed by extrusion past an extrusion point to form a sidewall portion of a lesser thickness. Extruding is stopped while some of the billet remains to form the closed bottom end. The preform has a bottom portion, a sidewall portion and a transition wall portion extending between the bottom portion and the sidewall portion. The transition wall portion is thicker than the sidewall portion and can be formed into at least part of the rim of an expansion shaped container. An impact extrusion punch has a central axis, an axially forward, impact surface for impacting metal to be extruded, a transition region for directing material displaced by the impact surface and a rear extrusion point for ironing material extruded past the transition region.

Abstract: An integrated insulator sealing and shielding assembly includes a rubber housing having a plurality of radial weathersheds and a tapered end adjacent an endmost radial weathershed. The tapered end has an outer surface with a ring extending outward from the outer surface. The ring is compressible. A metal end fitting is disposed adjacent to the endmost radial weathershed and receives the tapered end. The tapered end is received in a counterbore in the metal end fitting. The counterbore has a sealing surface so that interference of the ring with the sealing surface creates a compressive sealing force to form a seal.

Abstract: A refrigeration system, according to the present invention, has a standard refrigeration circuit, with a condenser connected to a low temperature evaporator and a medium temperature evaporator by a high-pressure liquid line, which are in turn connected to a compressor by a low-pressure vapour return line and a medium-pressure vapour return line, and the compressor is connected to the condenser by a high-pressure vapour line. A low-pressure booster is connected on the low-pressure vapour return line operating at a low compression ratio to boost the pressure of the low-pressure vapour return line to substantially the same pressure as the medium-pressure vapour return line.

Abstract: A deep neural network (DNN) media noise predictor configured for one-dimensional-magnetic (1DMR) recording or two-dimensional-magnetic (TDMR) is introduced. Such architectures are often combined with a trellis-based intersymbol interference (ISI) detection component in a turbo architecture to avoid the state explosion problem by separating the inter-symbol interference (ISI) detection and media noise estimation into two separate detectors and uses the turbo-principle to exchange information between them so as to address the modeling problem by way of training a DNN-based media noise estimators. Thus, beneficial aspects include a reduced bit-error rate (BER), an increased areal density, and a reduction in computational complexity and computational time.

Abstract: Compositions containing a nucleic acid nanostructure having a desired geometric shape and antigens bound to its surface are provided. The nanostructures can be, for example, in the form of a 6-helix bundle or icosahedron. The nanostructure design allows for control of the relative position and/or stoichiometry of the antigen bound to its surface. The antigens displayed on the nanostructure surface are arranged with the preferred number, spacing, and 3D organization to elicit a robust immune response. The displayed antigen can be an HIV immunogen such as eOD-GT6, eOD-GT8, or variants thereof. The compositions may thus be useful as immunogens, vaccines, immunostimulators, adjuvants, and the like. Methods of inducing immune responses, inducing protective immunity, inducing the production of neutralizing antibodies or inhibitory antibodies, inducing tolerance, and treating cancer, infectious or autoimmune diseases are also provided.

Abstract: An apparatus comprises a ground plane (2), an integrated circuit chip (1) disposed on the ground plane (2), the integrated circuit chip (1) comprising one or more electrically conductive layers (10) encircling a periphery of the integrated circuit chip (1), and a plurality of bondwires (9) electrically coupling the one or more electrically conductive layers (10) to the ground plane (2).

Abstract: A system includes a customer network and a telephony server. The customer network is associated with an independent carrier (IC), a native carrier, or both. The customer network includes a call manager, a telephone gateway, an internet gateway, a first device associated with the IC, and a second device associated with the native carrier. The first device communicates with the telephone gateway via the call manager. The second device communicates with the internet gateway. The telephony server is associated with the native carrier. The telephony server supports traffic from the first device and the second device. The telephony server includes a PBX and a session border controller (SBC). The SBC communicates with the telephone gateway via a session initiation protocol (SIP) trunk.

Abstract: A hollow preform impact extruded from a metal billet to produce a progressing wall at a transition wall thickness. An axially forward portion of the progressing wall is ironed by extrusion past an extrusion point to form a sidewall portion of a lesser thickness. Extruding is stopped while some of the billet remains to form the closed bottom end. The preform has a bottom portion, a sidewall portion and a transition wall portion extending between the bottom portion and the sidewall portion. The transition wall portion is thicker than the sidewall portion and can be formed into at least part of the rim of an expansion shaped container. An impact extrusion punch has a central axis, an axially forward, impact surface for impacting metal to be extruded, a transition region for directing material displaced by the impact surface and a rear extrusion point for ironing material extruded past the transition region.

Abstract: Systems and methods for eye tracking calibration in a wearable system are described. The wearable system can present three-dimensional (3D) virtual content and allow a user to interact with the 3D virtual content using eye gaze. During an eye tracking calibration, the wearable system can validate that a user is indeed looking at a calibration target while the eye tracking data is acquired. The validation may be performed based on data associated with the user's head pose and vestibulo-ocular reflex.