Abstract: Apparatus and methods for managing pain uses a single composite modulation/stimulation signal with variable characteristics to achieve the same results as separate varying electromagnetic signals, including spinal cord stimulation or peripheral nerve stimulation.

Abstract: A downhole system and method for producing and unloading from a well unloads a first fluid through a tubular in the well while blocking flow of a second fluid into the tubular. In an alternate mode, the second fluid is produced through the tubular while the first fluid is blocked from entering the tubular. In another alternate mode, a third fluid is unloaded through the tubular at the same the second fluid is produced from the well and through the tubular. In yet another alternate mode, the second fluid is pressurized downhole. In one example, the first fluid includes water, the second fluid includes a hydrocarbon gas, and the third fluid includes a hydrocarbon liquid. Means for unloading include a pump, means for pressurizing the second fluid include a compressor, and means for selectively blocking flow includes a flow circuit with one-way valves.

Abstract: The disclosed exemplary embodiments include computer-implemented systems, devices, apparatuses, and processes that maintain data confidentiality in communications involving voice-enabled devices operating within a distributed computing environment. By way of example, an apparatus may receive, from a communications system across a public communications network, a request for an element of data generated by the computing system based on first audio content obtained at a device. The apparatus may obtain the requested data element and further, may generate acoustic data representative of at least a portion of the requested data element. The apparatus may also generate an encrypted response to the received request that includes the acoustic data, and transmit the encrypted response to the device across the public communications network.

Abstract: The disclosed exemplary embodiments include computer-implemented systems, devices, apparatuses, and processes that maintain data confidentiality in communications involving voice-enabled devices in a distributed computing environment using homomorphic encryption. By way of example, an apparatus may receive encrypted command data from a computing system, decrypt the encrypted command data using a homomorphic private key, and perform operations that associate the decrypted command data with a request for an element of data. Using a public cryptographic key associated with a device, the apparatus generate an encrypted response that includes the requested data element, and transmit the encrypted response to the device. The device may decrypt the encrypted response using a private cryptographic key and to perform operations that present first audio content representative of the requested data element through an acoustic interface.

Abstract: A park release mechanism for a vehicle, including an upper housing and an assembleable lower housing. A cam with a projecting handle is arranged between the upper and lower housings and defines a range of pivotal rotation relative the housings. A cable is secured at one end to the cam and adapted to secure at an opposite end to a transmission of the vehicle. An unlock component is incorporated into the housing in communication with the cam and handle and, upon actuating, to shift the vehicle to and from a Park position upon actuation of the handle and displacement of the cable.

Abstract: A graphical display integrated into a linear gate vehicle shifter assembly including a surface display which can incorporate any of transistor LCD or organic LED interior components, such as which can be presented into either of segmented or OLED/TFT pixelated image display variants. In either instance, a connector end of an associated harness or ribbon cable extends from the graphical display and, when connected to a remote PCB board integrated into the shifter assembly, is configured to provide variable display options not limited to shifter position and including variable supporting graphics and other designs.

Abstract: A graphical display integrated into a rotary knob vehicle shifter assembly including a surface display located outside of the knob which can incorporate any of transistor LCD or organic LED interior components, such as which can be presented into either of segmented or OLED/TFT pixelated image display variants. In either instance, a connector end of an associated harness or ribbon cable extends from the graphical display and, when connected to a remote PCB board integrated into the shifter assembly, is configured to provide variable display options not limited to shifter position and including variable supporting graphics and other designs.

Abstract: The disclosed exemplary embodiments include computer-implemented systems, apparatuses, and processes that dynamically manage exchanges of data using a cryptographically secure distributed ledger and homomorphic commitments. For example, and in response to an occurrence of a triggering event, an apparatus may obtain parameter values that characterize the data exchange, first commitment values representative of the parameter values, and a first digital signature. In response to a verification of the first digital signature, the apparatus may apply a second digital signature to commitment data that includes the first commitment values and a second commitment value representative of the first digital signature. The apparatus may transmit a signal that includes the commitment data and the second digital signature to a computing system, which generates an element of distributed ledger that includes the commitment data and the second digital signature in response to a verification of the second digital signature.

Abstract: Methods, systems, and use cases for one-touch inline cryptographic data security are discussed, including an edge computing device with a network communications circuitry (NCC), an enhanced DMA engine coupled to a memory device and including a cryptographic engine, and processing circuitry configured to perform a secure exchange with a second edge computing device to negotiate a shared symmetric encryption key, based on a request for data. An inline encryption command for communication to the enhanced DMA engine is generated. The inline encryption command includes a first address associated with a storage location storing the data, a second address associated with a memory location in the memory device, and the shared symmetric encryption key. The data is retrieved from the storage location using the first address, the data is encrypted using the shared symmetric encryption key, and the encrypted data is stored in the memory location using the second address.

Abstract: A quick connect assembly having a male terminal with a plurality of circumferentially arrayed and elongated beams including forward-most arcuate projecting and outer diameter defining portions. A female terminal has a housing exhibiting an inner diameter inlet communicating with an interior arcuate and expanded extending recess which matches a profile defined by the outer diameter beam portions. A forwardly spring biased plug is displaceably supported within the female terminal housing and includes a forward most projecting snout portion which, upon installation of the male to female terminals, the projecting snout portion of the plug seats between the male beams, preventing unintended collapse and remove of the male beams from within the female housing.

Abstract: The disclosure relates to modified orthopoxvirus vectors, as well as methods of using the same for the treatment of various cancers. The disclosure provides modified orthopoxvirus vectors that exhibit various beneficial therapeutic activities, including enhanced oncolytic activity, spread of infection, immune evasion, tumor persistence, capacity for incorporation of exogenous DNA sequences and safety. The viruses we have discovered are also amenable to large scale manufacturing protocols.

Abstract: The disclosure relates to modified vaccinia virus vectors derived from the Copenhagen strain of vaccinia virus, as well as methods of using the same for the treatment of various cancers. The disclosure provides modified Copenhagen-derived vaccinia virus vectors that exhibit various beneficial therapeutic activities, including enhanced oncolytic activity, spread of infection, immune evasion, tumor persistence, capacity for incorporation of exogenous DNA sequences, amenability for large scale manufacturing, and safety.

Abstract: Disclosed are methods, apparatus, kits and compositions for determining the absence of a systemic bacterial infection (sepsis) in patients, particularly ones presenting to hospital emergency departments (ED) as outpatients, by measurement of the host immune response using peripheral blood. The are methods, apparatus, kits and compositions can be used in mammals for diagnosing, making treatment decisions, determining the next procedure or diagnostic test, or management of patients suspected of having an infection, including those presenting with fever or other signs of systemic inflammation. More particularly, peripheral blood RNA and protein biomarkers are disclosed that are useful for distinguishing between the host immune response to bacteria compared to the host immune response to other causes of systemic inflammation including trauma, burns, autoimmune disease, asthma, anaphylaxis, arthritis, obesity and viral infections.

Abstract: The disclosed exemplary embodiments include computer-implemented systems, apparatuses, and processes that dynamically manage exchanges of data using a cryptographically secure distributed ledger and homomorphic commitments. For example, and in response to an occurrence of a triggering event, an apparatus may obtain parameter values that characterize the data exchange, first commitment values representative of the parameter values, and a first digital signature. In response to a verification of the first digital signature, the apparatus may apply a second digital signature to commitment data that includes the first commitment values and a second commitment value representative of the first digital signature. The apparatus may transmit a signal that includes the commitment data and the second digital signature to a computing system, which generates an element of distributed ledger that includes the commitment data and the second digital signature in response to a verification of the second digital signature.

Abstract: Apparatus and methods for managing pain uses a multiplexed modulation/stimulation signal to provide pain relief during spinal cord stimulation or peripheral nerve stimulation.

Abstract: There is a provided a digital identity network interface system that may include a communications module and a processor. The processor may be configured to receive a signal representing a digital identity request, the digital identity request defining one or more scopes associated with the request, at least one of the scopes identifying a data type associated with the request, generate a query based on the scopes by translating at least one of the scopes into a query having a query format associated with a digital identity network, the digital identity network storing data associated with a plurality of users, send a signal representing the query to the digital identity network, send a link to an authorization device, after successful authentication, obtain data associated with the digital identity request from the digital identity network, and release at least some of the data.

Abstract: A device may detect a communication session between a user equipment and a network. The device may cause, based on detecting the communication session, a set of queries to be transmitted to a plurality of control plane nodes of the network. The device may determine, based on a set of responses associated with the set of queries, respective characteristics for corresponding control plane nodes, of the plurality of control plane nodes. The device may determine, based on the respective characteristics, scores for the corresponding control plane nodes, wherein the scores are representative of respective capabilities of the corresponding control plane nodes to be used for the communication session. The device may select, based on the scores, a control plane node, from the plurality of control plane nodes, for the communication session. The device may configure the control plane node to perform a control operation for the communication session.

Abstract: An exemplary lock cylinder includes a shell, a plug positioned in the shell, and a locking assembly. The locking assembly is configured to prevent rotation of the plug when no key is inserted, and to permit rotation of the plug upon insertion of any of a plurality of keys having different bitting profiles. The locking assembly may further be configured to prevent key extraction when the plug is in a rotated position.