Abstract: According to some embodiments, a pressure tolerant camera system includes: an enclosure filled with an incompressible fluid and having a viewport through which light can pass; a digital image sensor provided within the enclosure; and a plurality of mirror lenses provided within the enclosure and arranged to reflect light from the viewport onto the digital image sensor.

Abstract: Provided, in part, are compounds of Formula I: pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of conditions associated with the activity of sodium channels. Methods of treating a disease or condition relating to aberrant function of a sodium ion channel including neurological disorders (e.g., Dravet syndrome, epilepsy), pain, and neuromuscular disorders are also provided herein.

Abstract: The present disclosure relates to KRAS inhibitors. Methods of treatment cancers using the compounds are also provided.

Abstract: Systems and methods are described for optical processing. According to some aspects an apparatus may include a pixelated photodiode array (PDA), wherein each pixel in the PDA includes a radiation detector. The optical processing apparatus may also include a memory that stores one or more characteristics for each pixel in the PDA, and a read out integrated circuit (ROIC) communicatively coupled to the FPA and the memory. In some aspects, the ROIC reads from the memory the one or more characteristics for each pixel in the PDA, and adjusts an arm/disarm bias voltage for each pixel in the PDA based on the one or more characteristics of each pixel.

Abstract: The present invention relates to a substrate having (a) a first material applied to at least a portion of the substrate, and (b) a coating layer deposited from a powder coating composition including a film-forming resin, and optionally a crosslinker that is reactive with the film-forming resin, in direct contact with at least a portion of the substrate to which the first material has been applied. The first material is (i) a catalyst that catalyzes cure of the powder coating composition, (ii) a component reactive with the film-forming resin and/or the crosslinker of the powder coating composition, and/or (iii) a rheology modifier.

Abstract: A light-emitting user input device can include a touch sensitive portion configured to accept user input (e.g., from a user's thumb) and a light-emitting portion configured to output a light pattern. The light pattern can be used to assist the user in interacting with the user input device. Examples include emulating a multi-degree-of-freedom controller, indicating scrolling or swiping actions, indicating presence of objects nearby the device, indicating receipt of notifications, assisting pairing the user input device with another device, or assisting calibrating the user input device. The light-emitting user input device can be used to provide user input to a wearable device, such as, e.g., a head mounted display device.

Abstract: The present disclosure provides KRAS inhibitors. Methods of treating cancers using the compounds are also provided.

Abstract: A test system for testing a device having a plurality of electrical contacts. The test system comprising: a device table operable to hold at least one device under test, a probe comprising at least one probe end for contacting electrical contacts of a device under test, a movement mechanism operable to move one or both of the device table and the probe so as to bring the at least one probe end into contact with at least one electrical contact of a device under test, and a profile determining system configured to determine a profile of the electrical contacts of a device under test.

Abstract: An integrated circuit is fabricated by forming transistors having gates of orthogonal orientations and implanting, at two first rotations, a first pocket implant using a first dopant type with a masking pattern on a substrate surface layer, the two first rotations respectively forming two first pocket implantation angles and two first pocket implantation beam orientations, and implanting, at two second rotations, a retrograde gate-edge diode leakage (GDL) reduction pocket implant using a second dopant type with the masking pattern on the substrate surface layer, the two second rotations respectively forming two GDL-reduction implantation angles and two GDL-reduction implantation beam orientations.

Abstract: An apparatus for supporting a user includes a faceplate, an arm, a bridge, and a base. The bridge is rotatably attached to the faceplate to allow the faceplate to be pivotably adjusted. The bridge includes a hub with first and second hub bodies. Locking pins on the hub bodies slidingly engage pivot adjustment holes in first and second pivot adjustment rings. First and second buttons can be depressed to slide the hub bodies inwardly to separate the locking pins from the pivot adjustment holes to allow the hub to rotate, thereby allowing the faceplate to pivot. When the buttons are released, the hub bodies slide outwardly to insert the locking pins into the same or different pivot adjustment holes to prevent the hub from rotating.

Abstract: A method of access control includes receiving an access request transaction from one of a first identity sensor. Current confidence information is determined for the access request transaction. Prior confidence information is determined for at least one prior access request transaction associated with the user from at least one second identity sensor. A total confidence score value is generated based on a confidence function applied to the current confidence information and the prior confidence information. The total confidence score value is compared with a confidence threshold value for the secure resource associated with the access request transaction. Access to the secure resource is granted, in response to determining that the total confidence score value meets the confidence threshold value. The access to the secure resource is denied, in response to determining that the total confidence score value does not meet the confidence threshold value.

Abstract: The present invention is directed to, in part, fused heteroaryl compounds and compositions useful for preventing and/or treating a disease or condition relating to aberrant function of a voltage-gated, sodium ion channel, for example, abnormal late/persistent sodium current. Methods of treating a disease or condition relating to aberrant function of a sodium ion channel including neurological disorders (e.g., Dravet syndrome, epilepsy), pain, and neuromuscular disorders are also provided herein.

Abstract: The disclosure provides antibody molecules that bind to TCR V? regions and multispecific molecules comprising said antibody molecules. Additionally, disclosed are nucleic acids encoding the same, methods of producing the aforesaid molecules, pharmaceutical compositions comprising aforesaid molecules, and methods of treating a cancer using the aforesaid molecules.

Abstract: Systems, methods, and articles for assigning content, such as advertisements, to similar content breaks, such as advertisement placement opportunities, across multiple content providers. The systems disclosed herein automatically identify similar advertisement placement opportunities, such as advertisement placement opportunities occurring at the same time, across a plurality of media content providers, and assign an indicated advertisement spot to as many of the identified advertisement placement opportunities as possible. This is achieved by re-assigning advertisement spots which are already assigned to a slot in one of the advertisement placement opportunities to another slot in order to allow the indicated advertisement spot to be assigned to the slot.

Abstract: An apparatus for supporting a user includes a faceplate, an arm, a bridge, and a base. The bridge is rotatably attached to the faceplate to allow the faceplate to be pivotably adjusted. The bridge includes a hub with first and second hub bodies. Locking pins on the hub bodies slidingly engage pivot adjustment holes in first and second pivot adjustment rings. First and second buttons can be depressed to slide the hub bodies inwardly to separate the locking pins from the pivot adjustment holes to allow the hub to rotate, thereby allowing the faceplate to pivot. When the buttons are released, the hub bodies slide outwardly to insert the locking pins into the same or different pivot adjustment holes to prevent the hub from rotating.

Abstract: The disclosure provides antibody molecules that bind to TCR V? regions and multispecific molecules comprising said antibody molecules. Additionally, disclosed are nucleic acids encoding the same, methods of producing the aforesaid molecules, pharmaceutical compositions comprising aforesaid molecules, and methods of treating a cancer using the aforesaid molecules.

Abstract: The present invention is directed to, in part, fused heteroaryl compounds and compositions useful for preventing and/or treating a disease or condition relating to aberrant function of a voltage-gated, sodium ion channel, for example, abnormal late/persistent sodium current. Methods of treating a disease or condition relating to aberrant function of a sodium ion channel including neurological disorders (e.g., Dravet syndrome, epilepsy), pain, and neuromuscular disorders are also provided herein.

Abstract: A medical imaging system includes a CT imaging system including a gantry having a bore, rotatable about an axis of rotation. The CT imaging system includes a table configured to move a subject to be imaged into and out of the bore, a radiation source mounted on the gantry and configured to emit an X-ray beam, and a detector configured to detect the X-ray beam. The medical imaging system includes a LiDAR scanning system physically coupled to the CT imaging system. The LiDAR scanning system is configured to acquire data of the subject from different angular positions relative to the axis of rotation. The medical imaging system includes processing circuitry configured to receive the data acquired with the LiDAR scanning system, to generate a three-dimensional (3D) measurement of the subject, and to utilize the 3D measurement in a subsequent workflow process for a CT scan of the subject.

Abstract: The present invention is directed to, in part, fused heteroaryl compounds and compositions useful for preventing and/or treating a disease or condition relating to aberrant function of a voltage-gated, sodium ion channel, for example, abnormal late/persistent sodium current. Methods of treating a disease or condition relating to aberrant function of a sodium ion channel including neurological disorders (e.g., Dravet syndrome, epilepsy), pain, and neuromuscular disorders are also provided herein.