Abstract: The present invention is directed to 3-(ethoxydifluoromethyl)-6-(5-fluoro-6-(2,2,2-trofluoroethoxy)pyridine-3-yl)-[1,2,4]triazolo[4,3-a]pyridine, or a pharmaceutically acceptable salt thereof, or a composition thereof, which is useful for preventing and/or treating a disease or condition relating to aberrant function of a voltage-gated, sodium ion channel, for example, abnormal late/persistent sodium current. Methods of treating a disease or condition relating to aberrant function of a sodium ion channel including neurological disorders (e.g., Dravet syndrome, epilepsy), pain, and neuromuscular disorders are also provided herein.

Abstract: The present invention is directed to 3-(ethoxydifluoromethyl)-6-(5-fluoro-6-(2,2,2-trofluoroethoxy)pyridine-3-yl)-[1,2,4]triazolo[4,3-?]pyridine, or a pharmaceutically acceptable salt thereof, or a composition thereof, which is useful for preventing and/or treating a disease or condition relating to aberrant function of a voltage-gated, sodium ion channel, for example, abnormal late/persistent sodium current. Methods of treating a disease or condition relating to aberrant function of a sodium ion channel including neurological disorders (e.g., Dravet syndrome, epilepsy), pain, and neuromuscular disorders are also provided herein.

Abstract: A capacitor device comprised of a first conductor layer fabricated from a first material located between two dielectric layers located between second set of conductor layers fabricated from a second material located between two additional dielectric layers and at least another two first conductors. The first conductor layers all being electrically connected to one another and the second conductor layers being electrically connected to one another and not electrically connected to the first conductor for the purpose of storing electrical charge.

Abstract: Systems, methods, and articles for optimizing the placement of content, such as advertisements, within content breaks. The systems disclosed herein automatically identify the optimal allocation of content within breaks included in advertisement placement opportunities. This is achieved by scoring placed advertisements and determining whether a prospective advertisement can be placed within a break. The system may score the placed advertisements based on rules provided by a media content provider and multiple buyers.

Abstract: An in-line security device to transfer cryptographic key material, the device comprising: a first connector configured to connect, via wire, with a host device; a second connector configured to connect, via wire, with a data storage device; a pass-through circuit between the first connector and the second connector to facilitate data communication between the host device and the data storage device; and a communication interface to send cryptographic key material to the data storage device via the second connector.

Abstract: The present application describes a network interface device that acts as an interface between a network service provided by a network service provider and one or more network access devices associated with a particular location and/or entity.

Abstract: Various implementations include a compliant element comprising a spring component, a mounting portion, and a transverse shear constraint element. The spring component comprises two or more stacked beam elements. Each beam element has a first and second end with the first end of each beam is attached to the mounting portion. Furthermore, the transverse shear constraint element is located between the first and second ends of the beam elements and prevents the relative sliding of two or more beam elements in the region of the beams between the first beam ends and the transverse shear constraint element.

Abstract: A network interface device bracket and a method of connecting a network device to a network via the network interface device bracket is provided. According to an example, the network interface device bracket may be adapted to be removably attached to the network interface device and removably mounted to a mounting surface. The network interface device bracket may include an internal housing that is adapted to connect a jumper cable connected to the network interface device to a drop cable connected to a service provider network and to store excess drop cable.

Abstract: The disclosure provides antibody molecules that bind to TCR VP regions and multispecific molecules comprising said antibody molecules. Additionally, disclosed are nucleic acids encoding the same, methods of producing the aforesaid molecules, pharmaceutical compositions comprising aforesaid molecules, and methods of treating a cancer using the aforesaid molecules.

Abstract: The present disclosure provides a method for forming a semiconductor device containing MOS transistors both with and without source/drain extension regions in a semiconductor substrate having a semiconductor material on either side of a gate structure including a gate electrode on a gate dielectric formed in a semiconductor material. In devices with source/drain extensions, a diffusion suppression species of one or more of indium, carbon and a halogen are used. The diffusion suppression implant can be selectively provided only to the semiconductor devices with drain extensions while devices without drain extensions remain diffusion suppression implant free.

Abstract: Processing a payment transaction from a payer (operating a payer computing system) to a payee (operating a merchant computing system) by a secure computing system. The secure computing system outputs a financial account registration request form to the payer computing system (e.g., within a window or frame that is displayed within an ecommerce webpage provided by the merchant computing system) for the payer to provide sensitive financial account information, securely stores the sensitive financial account information, maintains compliance with an information security standard (e.g., a Payment Card Industry Data Security Standard), and provides a non-sensitive electronic data token representing the sensitive financial account information to the merchant computing system.

Abstract: The present invention is directed to, in part, fused heteroaryl compounds and compositions useful for preventing and/or treating a disease or condition relating to aberrant function of a voltage-gated, sodium ion channel, for example, abnormal late/persistent sodium current. Methods of treating a disease or condition relating to aberrant function of a sodium ion channel including Dravet syndrome or epilepsy are also provided herein.

Abstract: A capacitor device to store electrical charge is disclosed that includes a first unit of a first conductor layer fabricated from a first material. The first conductor layer is sandwiched between two dielectric layers. This assembly is layered on a second unit of a second conductor layer fabricated from a second material and sandwiched between two additional dielectric layers. The first conductor layers are all electrically connected to one another, and the second conductor layers being electrically connected to one another but are not electrically connected to the first conductor. Any multiple of first and second units may be utilized.

Abstract: A light emitting user input device can include a touch sensitive portion configured to accept user input (e.g., from a user's thumb) and a light emitting portion configured to output a light pattern. The light pattern can be used to assist the user in interacting with the user input device. Examples include emulating a multi-degree-of-freedom controller, indicating scrolling or swiping actions, indicating presence of objects nearby the device, indicating receipt of notifications, assisting pairing the user input device with another device, or assisting calibrating the user input device. The light emitting user input device can be used to provide user input to a wearable device, such as, e.g., a head mounted display device.

Abstract: In an embodiment, an apparatus includes: a gearbox including: a housing having an opening; an input pinion disposed in the housing; a moving feature mechanically coupled to the input pinion, the moving feature and the input pinion being operable to convert between power and torque; and first sensors disposed on the moving feature, the first sensors having batteries, where the moving feature is operable to rotate about a common axis, each of the first sensors being exposed by the opening as the moving feature rotates about the common axis.

Abstract: Devices for the separation of components within a fluid are disclosed herein. The device includes a housing that contains a roll of film with spaced apart microstructures thereon to crate channels to direct fluid flow. The channels have functionalized surfaces to attract and retain desired components in the fluid so that those components can be separated from the fluid. The film roll is typically contained by an outer sleeve around its perimeter to contain the fluid therein. The device also includes a central hub on which the film roll is mounted.

Abstract: A method includes: producing a light beam made up of pulses having a wavelength in the deep ultraviolet range, each pulse having a first temporal coherence defined by a first temporal coherence length and each pulse being defined by a pulse duration; for one or more pulses, modulating the optical phase over the pulse duration of the pulse to produce a modified pulse having a second temporal coherence defined by a second temporal coherence length that is less than the first temporal coherence length of the pulse; forming a light beam of pulses at least from the modified pulses; and directing the formed light beam of pulses toward a substrate within a lithography exposure apparatus.

Abstract: A fill pack includes a first sheet and a second sheet. The first sheet has a first end, a second end and a first plurality of flutes. A first microstructure includes first top flat strips, first bottom flat strips and first conduit sides connecting the first top flat strips to the first bottom flat strips. A plurality of first radii connect the first top flat strips to the first conduit sides and the first bottom flat strips to the first conduit sides. The second sheet has a second plurality of flutes. A second microstructure includes second top flat strips, second bottom flat strips and second conduit sides connecting the second top flat strips to the second bottom flat strips. A plurality of second radii connect the second top flat strips to the second conduit sides and second bottom flat strips to the second conduit sides.

Abstract: A portable electronic device may be configured for play of a video game, with user controlled game characters operated based on inputs received on first user inputs of the device and a virtual game world modified based on information from motion-related sensors of the device. The modification of the virtual game world may be rotation and/or translation of the virtual game world in a gravitational reference frame. The portable electronic device may also allow for user configuration of the virtual game world.

Abstract: A method and system for estimating a full elastic tensor. The method may comprise taking a measurement for compressional wave sonic data and cross-dipole shear data with a sonic logging tool at a first location as cross-dipole data, processing the compressional wave sonic data to produce a compressional wave slowness (P), and processing the cross-dipole shear data to produce a fast horizontal polarized shear wave slowness (SH) and a slow quazi-vertical shear wave slowness (qSV) as a function of depth. The method may further comprise setting an initial guess for at least five constants of the full elastic tensor for Vertical Transversely Isotropy (VTI) symmetry, determining a modeled slowness surfaces from the full elastic tensor, and comparing the modeled slowness surfaces with measured values of the P, the SH, and the qSV. The method may be performed by a system comprising a sonic logging tool and an information handling system.