Abstract: An assembly includes a cone having a tapered outer surface, a slips assembly positioned at least partially around the tapered outer surface of the cone, and a sealing ring positioned at least partially around the tapered outer surface of the cone. The slips assembly directly engages the sealing ring, such that the slips assembly is configured to transmit a setting force to the sealing ring, which moves the sealing ring on the tapered outer surface of the cone and expands the sealing ring radially outward. The assembly includes an anti-seal ring positioned adjacent to the sealing ring and around the cone. The anti-seal ring is driven along the tapered outer surface of the cone by engagement with the sealing ring.

Abstract: A method monitors the state of a device having a first drive cylinder for receiving hydraulic fluid and a first drive piston which is movably arranged in the first drive cylinder. The method determines a speed of the first drive piston, establishes a difference between the determined speed of the first drive piston and an expected speed of the first drive piston, and determines a faulty state as a function of the difference established between the determined speed of the first drive piston and the expected speed of the first drive piston.

Abstract: A cooking oven wet bulb sensor system having: a reservoir configured to be secured to a cooking chamber wall of the cooking oven, with a cavity of the reservoir in an upward-facing orientation; a temperature sensor probe configured to be mounted at least partially within the cavity of the reservoir; and a water fill opening positioned to dispense water into the cavity. A cooking oven having a wet bulb sensor system and a method for operating a cooking oven are also provided.

Abstract: Systems and methods of a monitoring node to assist an air navigation service provider (ANSP) in the design of an airspace. The monitoring node collects flight data and performs flight simulations for a large geographic region that is outside of the airspace. The monitoring node receives flight data collected by the ANSP for the airspace. The monitoring node supplements their flight data with the data received from the ANSP and performs flight simulations and generates flight plans for the airspace. The flight simulations and flight plans are transmitted to the ANSP which are then used by the ANSP to design the airspace.

Abstract: The present invention provides 1H-pyrazolo[4,3-b]pyridin-7-amines of formula (I) as PDE1 inhibitors together with a second compound useful in the treatment of a neurodegenerative disorder and their combined use as a medicament, in particular for the treatment of neurodegenerative and/or cognitive disorders.

Abstract: According to the present disclosure there is provided a transmitter unit for providing power and data to an unmanned aerial vehicle (UAV), the transmitter unit comprising: a free-space optical transmitter configured to generate and transmit a combined free-space optical beam comprising a power beam and a data beam; and a controller for controlling generation and transmission of the combined free-space optical beam by the free-space optical transmitter. Also disclosed is a receiver unit mountable on an unmanned aerial vehicle (UAV) for receiving power and data at the UAV, the receiver unit comprising an optical receiver configured to receive at least a portion of a combined free space optical beam comprising a power beam and a data beam, the receiver unit configured to convert the received power beam portion into local electrical power and convert the received data beam portion into one or more data signals.

Abstract: The present invention relates to c-di-GMP lowering chemical compounds having anti- biofilm properties. In particular, the present invention relates to anti-biofilm compounds or salts or tautomers thereof for use in treatment and/or prevention of bacterial biofilm infection in human subjects caused by biofilm-forming bacteria of the genus Pseudomonas, in particular Pseudomonas spp. including P. aeruginosa. Methods of treating such infections in human subjects are contemplated as well. The present inventions further relates to the use of an anti-biofilm compound or a salt or tautomer thereof for dispersing biofilms in industrial water systems.

Abstract: Aspects of the subject disclosure may include, for example, an AT command that allows an application service provider to modify suspend/resume (S/R) and/or deactivate/activate (D/A) functionality specified in one or more elementary files of a UICC. The S/R and/or D/A functionality can be influenced by the application service provider without relying on SIM-OTA messages being forwarded by a mobile operator. Other embodiments are disclosed.

Abstract: The invention is directed to systems, apparatus and kits for automated synthesis of a plurality of polynucleotides in an array of reaction chambers using a template-free polymerase. In some embodiments, adaptive elements and processes are provided to monitor and control disruption of the synthesis process and fluid movement by enzyme aggregation.

Abstract: The present invention provides 1H-pyrazolo[4,3-b]pyridin-7-amines of formula (I) as PDE1 inhibitors together with a second compound which compound is useful in the treatment of a psychiatric disorder and their combined use as a medicament, in particular for the treatment of psychiatric and/or cognitive disorders.

Abstract: There is provided a limb exercise device comprising: a force sensor configured to determine a weight applied to the device; a sliding component configured to facilitate the sliding movement of the device along a separate surface, wherein the separate surface is a surface that is separate to the device, wherein the sliding component comprises a part of an external housing of the device; a device movement sensor configured to determine a movement of the device on the separate surface; a limb position sensor configured to determine a position, in at least one dimension, of a limb of a user positioned above or adjacent to the device; and an output device configured to output an indication in dependence on a signal from at least one of: the force sensor, the device movement sensor and the limb position sensor.

Abstract: An equipment enclosure (1) for electromagnetically isolating an electronic device, the equipment enclosure 1 comprising a conductive housing (3) and a plurality of conductive sheets (5). Each sheet (5) includes an aperture (7). The sheets (5) are stacked in a spaced-apart relationship within the housing (3) thereby defining a plurality of electromagnetically-isolated cavities (9) each within a respective Faraday cage formed by the conductive housing (3) and the conductive sheets (5). The apertures (7) form a channel (11) that extends through the enclosure (1) providing a route for connections between the cavities (9).

Abstract: There is provided a thermal management apparatus for use with a vehicle comprising: a chassis in thermal contact with one or more first components that require thermal management and one or more second components that require thermal management, wherein the chassis is configured to transfer heat from the one or more first components to the one or more second components.

Abstract: The present invention provides 1H-pyrazolo[4,3-b]pyridin-7-amines of formula (1) as PDE1 inhibitors and their use as a medicament, in particular for the treatment of neurodegenerative disorders and psychiatric disorders.

Abstract: There is provided a thermal management apparatus for use with a vehicle comprising: a chassis in thermal contact with one or more first components that require thermal management and one or more second components that require thermal management, wherein the chassis is configured to transfer heat from the one or more first components to the one or more second components.

Abstract: The invention provides methods and compositions for breeding pepper (Capsicum sp. such as Capsicum annuum) lines, including isogenic and nearly isogenic lines, displaying one or more mature fruit color(s) of interest. Predictive genetic markers and associated sequences and primers, associated with phenotypic diversity at the Ccs locus encoding Capsanthin-Capsorubin Synthase, and the Ze locus encoding Zeaxanthin Epoxidase are also provided, as well as methods for breeding pepper lines. Further provided are pepper plants, and plant parts including seeds, seed mixtures, fruit, and packaged fruit, which display mature fruit color(s) of interest.

Abstract: An equipment enclosure (1) for electromagnetically isolating an electronic device, the equipment enclosure 1 comprising a conductive housing (3) and a plurality of conductive sheets (5). Each sheet (5) includes an aperture (7). The sheets (5) are stacked in a spaced-apart relationship within the housing (3) thereby defining a plurality of electromagnetically-isolated cavities (9) each within a respective Faraday cage formed by the conductive housing (3) and the conductive sheets (5). The apertures (7) form a channel (11) that extends through the enclosure (1) providing a route for connections between the cavities (9).

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for performing visual tracking. In one aspect, a method comprises receiving: (i) one or more reference video frames, (ii) respective reference labels for each of a plurality of reference pixels in the reference video frames, and (iii) a target video frame. The reference video frames and the target video frame are processed using a colorization machine learning model to generate respective pixel similarity measures between each of (i) a plurality of target pixels in the target video frame, and (ii) the reference pixels in the reference video frames. A respective target label is determined for each target pixel in the target video frame, comprising: combining (i) the reference labels for the reference pixels in the reference video frames, and (ii) the pixel similarity measures.

Abstract: Disclosed is an optical flow cell (300?) comprising: a housing (910) forming; an enclosed and elongated fluid channel (920) arranged along a first axis (923); a first light guide (961) and a second light guide (962) generally concentrically arranged along a second axis (970) and on opposite side walls of the fluid channel, said first and second light guides having ends (961c,962c) removed in situ to provide a sensing gap (d).

Abstract: A downhole tool includes a sleeve having a first end and a second end, a slip assembly coupled to the second end of the sleeve, a first cone positioned at least partially in the sleeve, proximal to the first end thereof, and a second cone positioned at least partially in the slip assembly. The first and second cones are configured to be moved toward one another from a run-in configuration to a set configuration. When actuating from the run-in configuration to the set configuration, the sleeve is forced radially outward by the first cone. When actuating from the run-in configuration to the set configuration, the slip assembly is forced radially outward by the second cone.