Abstract: A downhole tool includes a sleeve having a first end and a second end, a slip assembly coupled to the second end of the sleeve, a first cone positioned at least partially in the sleeve, proximal to the first end thereof, and a second cone positioned at least partially in the slip assembly. The first and second cones are configured to be moved toward one another from a run-in configuration to a set configuration. When actuating from the run-in configuration to the set configuration, the sleeve is forced radially outward by the first cone. When actuating from the run-in configuration to the set configuration, the slip assembly is forced radially outward by the second cone.

Abstract: A downhole tool includes an expandable sleeve. The expandable sleeve includes a lower portion and an upper portion. The downhole tool also includes a lower cone positioned at least partially within the lower portion of the expandable sleeve. The downhole tool also includes an upper cone positioned at least partially within the upper portion of the expandable sleeve. The lower and upper cones are configured to expand the respective lower and upper portions of the expandable sleeve radially outward when the lower and upper cones are adducted toward one another. The downhole tool also includes an isolation device extending through the bore of the expandable sleeve and positioned radially inward of the lower and upper cones. The isolation device is configured to engage the upper cone so as to block fluid flow therethrough in at least one direction.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for performing action localization in images and videos. In one aspect, a system comprises a data processing apparatus; a memory in data communication with the data processing apparatus and storing instructions that cause the data processing apparatus to perform image processing and video processing operations comprising: receiving an input comprising an image depicting a person; identifying a plurality of context positions from the image; determining respective feature representations of each of the context positions; providing a feature representation of the person and the feature representations of each of the context positions to a context neural network to obtain relational features, wherein the relational features represent relationships between the person and the context positions; and determining an action performed by the person using the feature representation of the person and the relational features.

Abstract: A downhole tool includes a cone having a tapered outer surface, a slip assembly positioned at least partially around the tapered outer surface of the cone, and a sealing ring positioned at least partially around the tapered outer surface of the cone. The slip assembly directly engages the sealing ring, such that the slip assembly is configured to transmit a setting force directly onto the sealing ring, which moves the sealing ring on the tapered outer surface of the cone and expands the sealing ring radially outward.

Abstract: An assembly includes a cone having a tapered outer surface, a slips assembly positioned at least partially around the tapered outer surface of the cone, and a sealing ring positioned at least partially around the tapered outer surface of the cone. The slips assembly directly engages the sealing ring, such that the slips assembly is configured to transmit a setting force to the sealing ring, which moves the sealing ring on the tapered outer surface of the cone and expands the sealing ring radially outward. The assembly includes an anti-seal ring positioned adjacent to the sealing ring and around the cone. The anti-seal ring is driven along the tapered outer surface of the cone by engagement with the sealing ring.

Abstract: Disclosed is an optical flow cell (300?) comprising: a housing (910) forming; an enclosed and elongated fluid channel (920) arranged along a first axis (923); a first light guide (961) and a second light guide (962) generally concentrically arranged along a second axis (970) and on opposite side walls of the fluid channel, said first and second light guides having ends (961c,962c) removed in situ to provide a sensing gap (d).

Abstract: An electromagnetic flow sensor for an electromagnetic flow meter (201) is disclosed. The sensor comprises a body (204) or frame, a flow passage (252) through the body or frame, a part of a magnetic circuit (248, 295) supported by the body or frame for applying a magnetic field across the flow passage, and at least first and second electrodes (298) supported by the body or frame, the at least first and second electrodes arranged to sense a voltage in response to a conductive fluid flowing through the flow passage. At least a portion of the body supporting the magnetic circuit part and the at least first and second electrodes is configured to be insertable into a flow tube (206) through a single aperture in the flow tube.

Abstract: The present invention relates to an enclosure and method of manufacture of an enclosure arranged to define a cavity for electromagnetic shielding of equipment to be housed within the cavity, the enclosure comprising: an aperture (16) arranged to allow access to the enclosure; a conductive membrane (18) arranged to close the aperture; and a waveguide element (20) arranged between the conductive membrane (18) and the cavity; wherein the waveguide element (20) and conductive membrane (18) are configured to attenuate electromagnetic radiation originating from the equipment to be housed within the enclosure (10) thereby to inhibit the transmission of electromagnetic radiation from the enclosure via the aperture (16).

Abstract: The present invention provides 1H-pyrazolo[4,3-b]pyridin-7-amines of formula (1) as PDE1 inhibitors and their use as a medicament, in particular for the treatment of neurodegenerative disorders and psychiatric disorders.

Abstract: The present invention provides 1H-pyrazolo[4,3-b]pyridin-7-amines of formula (I) as PDE1 inhibitors and their use as a medicament, in particular for the treatment of neurodegenerative disorders and psychiatric disorders.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for performing action localization. In one aspect, a system comprises a data processing apparatus; a memory in data communication with the data processing apparatus and storing instructions that cause the data processing apparatus to perform operations comprising: receiving an input comprising an image depicting a person; identifying a plurality of context positions from the image; determining respective feature representations of each of the context positions; providing a feature representation of the person and the feature representations of each of the context positions to a context neural network to obtain relational features, wherein the relational features represent relationships between the person and the context positions; and determining an action performed by the person using the feature representation of the person and the relational features.

Abstract: A downhole tool includes an expandable sleeve having an outer surface. The expandable sleeve is configured to expand radially outwards without fracturing apart. The tool also includes a plurality of button inserts positioned at least partially in the expandable sleeve and extending outward past the outer surface by a first distance, so as to engage a surrounding tubular when the expandable sleeve is expanded. The tool further includes a first band of grit material on the outer surface, adjacent to at least one row of the plurality of button inserts. The first band of grit material extends outward from the outer surface by at least the first distance, to shield the plurality of button inserts during run-in of the downhole tool.

Abstract: The present disclosure provides pepper plants exhibiting resistance to Phytophthora capsici. Such plants may comprise novel introgressed chromosomal regions associated with disease resistance. In certain aspects, compositions, including novel polymorphic markers and methods for producing, breeding, identifying, and selecting plants or germplasm with a disease resistance phenotype are provided.

Abstract: The invention provides methods and compositions for breeding pepper (Capsicum sp. such as Capsicum annuum) lines, including isogenic and nearly isogenic lines, displaying one or more mature fruit color(s) of interest. Predictive genetic markers and associated sequences and primers, associated with phenotypic diversity at the Ccs locus encoding Capsanthin-Capsorubin Synthase, and the Ze locus encoding Zeaxanthin Epoxidase are also provided, as well as methods for breeding pepper lines. Further provided are pepper plants, and plant parts including seeds, seed mixtures, fruit, and packaged fruit, which display mature fruit color(s) of interest.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for performing visual tracking. In one aspect, a method comprises receiving: (i) one or more reference video frames, (ii) respective reference labels for each of a plurality of reference pixels in the reference video frames, and (iii) a target video frame. The reference video frames and the target video frame are processed using a colorization machine learning model to generate respective pixel similarity measures between each of (i) a plurality of target pixels in the target video frame, and (ii) the reference pixels in the reference video frames. A respective target label is determined for each target pixel in the target video frame, comprising: combining (i) the reference labels for the reference pixels in the reference video frames, and (ii) the pixel similarity measures.

Abstract: The present invention provides 1H-pyrazolo[4,3-b]pyridin-7-amines of formula (I) as PDE1 inhibitors and their use as a medicament, in particular for the treatment of neurodegenerative disorders and psychiatric disorders.

Abstract: The present invention provides 1H-pyrazolo[4,3-b]pyridin-7-amines of formula (1) as PDE1 inhibitors and their use as a medicament, in particular for the treatment of neurodegenerative disorders and psychiatric disorders.

Abstract: The present invention provides 1H-pyrazolo[4,3-b]pyridin-7-amines of formula (I) as PDE1 inhibitors together with a second compound useful in the treatment of a neurodegenerative disorder and their combined use as a medicament, in particular for the treatment of neurodegenerative and/or cognitive disorders.

Abstract: The present invention provides 1H-pyrazolo[4,3-b]pyridin-7-amines of formula (I) as PDE1 inhibitors together with a second compound which compound is useful in the treatment of a psychiatric disorder and their combined use as a medicament, in particular for the treatment of psychiatric and/or cognitive disorders.

Abstract: The present disclosure provides pepper plants exhibiting resistance to Phytophthora capsici. Such plants may comprise novel introgressed chromosomal regions associated with disease resistance. In certain aspects, compositions, including novel polymorphic markers and methods for producing, breeding, identifying, and selecting plants or germplasm with a disease resistance phenotype are provided.