Abstract: Inhibitors of SecA, and methods of making and using thereof, are described herein. The compounds described herein can be used to treat or prevent microbial infections, such as bacterial infections.

Abstract: The present disclosure provides a memory. The memory includes an array of memory cells arranged as a plurality of rows by a plurality of columns. A memory cell is connected to at least one redundant memory cell in series in a same row for storing same data as the memory cell; and a column of memory cells correspond to at least one redundant column of redundant memory cells wherein each redundant memory cell in the at least one redundant column stores same data as the memory cell in a same row.

Abstract: The present disclosure provides a memory. The memory includes an array of memory cells arranged as a plurality of rows by a plurality of columns. A memory cell is connected to at least one redundant memory cell in series in a same row for storing same data as the memory cell; and a column of memory cells correspond to at least one redundant column of redundant memory cells wherein each redundant memory cell in the at least one redundant column stores same data as the memory cell in a same row.

Abstract: A pressure detection method for an in-cell touch display and a mobile device using the same are provided. The pressure detection method comprises the steps of: providing a common voltage plane corresponding to touch sensing electrodes in the in-cell touch display; detecting capacitance values of the touch sensing electrodes; setting a first area and a second area according to a center of a touched portion when the in-cell touch display is determined as being touched, wherein the second area includes the first area; and excluding the capacitance values of the touch sensing electrodes in the first area, and using the capacitance values of the touch sensing electrodes in the second area to serve as a pressure detection value to determine a pressure exerted on the in-cell touch display.

Abstract: A through via structure includes a conductive wiring, at least one dielectric layer over the conductive wiring, a via hole in the at least one dielectric layer and exposing the conductive wiring, and a conductive via in the via hole. The conductive via includes a conductive barrier layer in a bottom portion of the via hole, and a conductive layer in a top portion of the via hole.

Abstract: Compositions and methods for reconstituting a protein of interest in the plasma membrane of a Xenopus oocyte are disclosed. The method generally includes combining a preassembled membrane protein or proteins with a liposome to prepare a proteo-liposome. The proteo-liposome can have a specific composition of lipids. The proteo-liposome is incubated for sufficient time and under conditions suitable for the protein of interest to fold, associate with, or insert into the liposome's lipid bilayer. In some embodiments, the protein or proteins assemble into a protein channel or complex on or in the proteo-liposome's membrane. The treated oocytes can be used to determine the structure, function, or activity of the membrane protein of interest, the effect of a lipid microenvironment on a membrane protein of interest, or to identify compounds that modulate the function or activity of the membrane protein of interest.

Abstract: A bandgap reference circuit and method of using the same are provided. The bandgap reference circuit includes a startup component; an output component; and a bandgap core component coupled there-between. The bandgap core component includes a reference point having a voltage associated with an output signal of the output component. A controller is configured for controlling the bandgap core component and the output component to switch between a low power consumption mode and a normal operation mode based on the voltage at the reference point. When the bandgap core component and the output component operate in the normal operation mode, the bandgap reference circuit outputs a stable voltage and has a first power consumption. When the bandgap core component and the output component operate in the low power consumption mode, the bandgap reference circuit has a second power consumption less than the first power consumption.

Abstract: Inhibitors of SecA, and methods of making and using thereof, are described herein. The compounds described herein can be used to treat or prevent microbial infections, such as bacterial infections.

Abstract: A method operates a bandgap voltage reference circuit that includes a bias circuit for receiving a feedback signal and outputting a bias signal, an amplifier for receiving the bias signal and outputting a first reference signal as the feedback signal, an output circuit for receiving the first reference signal and outputting a second reference signal, and an output switch for outputting the second reference signal as an output signal. The method includes, after powering up the bandgap voltage reference circuit, determining whether the output signal is stable, when the output signal is stable, turning off the output switch; turning off the bias circuit; and turning off the output circuit. The sequential turning off the output switch, the output circuit, and the bias circuit puts the bandgap voltage reference circuit into a sleep mode to save power.

Abstract: A semiconductor structure includes a substrate and a fin. The fin extends from the substrate and is formed with a hole therethrough. The hole is defined by a confronting pair of wall parts. One of the wall parts is more arcuate than the other of the wall parts. A method for fabricating the semiconductor structure is also disclosed.

Abstract: A touch display apparatus includes a first substrate including first and second surfaces, a second substrate having a side facing the second surface and provided with a pixel electrode layer, an insulator layer and a common electrode layer, and a liquid crystal (LC) layer disposed between the first and second substrates. The second surface is provided with opening areas, a non-opening area surrounding the opening areas, a black matrix layer, a color filter layer, a protection layer, a touch electrode layer, first and second flat layers, and a patterned viewing angle control transparent electrode layer including control electrode members disposed corresponding to the opening areas, first connection electrode members disposed corresponding to the non-opening area in a first direction and connected to the control electrode members, and second connection electrode members disposed corresponding to the non-opening area in a second direction and connected to the first connection electrode members.

Abstract: Disclosed herein are methods for treating a neurodevelopmental disorder in a subject in need thereof. The method includes administering to the subject in need thereof an effective amount of a methyl-CpG-binding protein 2 (MeCP2) or a nucleic acid encoding the MeCP2 to alleviate or ameliorate the symptoms associated with the neurodevelopmental disorder. According to preferred embodiments, the MeCP2 has one or more post-translational modifications that result in increased levels of sumoylation, phosphorylation or both, as compared with that of the endogenous MeCP2 in the subject.

Abstract: Methods of and device for retaining a moisture level of a food heated/reheated in a microwave oven are provided. The device includes a microwave splatter cover, a lid, or a lunch box integrated with a steam generator. The device is able to contain a steam generator capable of generating steam from added water when a microwave radiation is provided. The steam generator is able to rotatably couple with the center of the microwave cover. Water added to the cover is able to be temporary stored on the cover and subsequently flow to a dish structure underneath the cover. Alternatively, water is able to be added directly through a hole on the cover to the dish structure.

Abstract: The present disclosure provides a memory. The memory includes an array of memory cells arranged as a plurality of rows by a plurality of columns. A memory cell is connected to at least one redundant memory cell in series in a same row for storing same data as the memory cell; and a column of memory cells correspond to at least one redundant column of redundant memory cells wherein each redundant memory cell in the at least one redundant column stores same data as the memory cell in a same row.

Abstract: The present disclosure provides a memory. The memory includes an array of memory cells arranged as a plurality of rows by a plurality of columns. A memory cell is connected to at least one redundant memory cell in series in a same row for storing same data as the memory cell; and a column of memory cells correspond to at least one redundant column of redundant memory cells wherein each redundant memory cell in the at least one redundant column stores same data as the memory cell in a same row.

Abstract: A pressure detection method for an in-cell touch display and a mobile device using the same are provided. The pressure detection method comprises the steps of: providing a common voltage plane corresponding to touch sensing electrodes in the in-cell touch display; detecting capacitance values of the touch sensing electrodes; setting a first area and a second area according to a center of a touched portion when the in-cell touch display is determined as being touched, wherein the second area includes the first area; and excluding the capacitance values of the touch sensing electrodes in the first area, and using the capacitance values of the touch sensing electrodes in the second area to serve as a pressure detection value to determine a pressure exerted on the in-cell touch display.

Abstract: Methods of and device for retaining a moisture level of a food heated/reheated in a microwave oven are provided. The device includes a microwave splatter cover, a lid, or a lunch box integrated with a steam generator. The device is able to contain a steam generator capable of generating steam from added water when a microwave radiation is provided. The steam generator is able to rotatably couple with the center of the microwave cover. Water added to the cover is able to be temporary stored on the cover and subsequently flow to a dish structure underneath the cover. Alternatively, water is able to be added directly through a hole on the cover to the dish structure.

Abstract: A method for detecting metal ions and chemical/biochemical molecules is provided. The method includes providing a probe, wherein the probe includes: a gold nanocluster; a reducing agent and a chelating agent partially capped on a surface of the gold nanocluster, wherein the probe is formed of reducing gold ions by the reducing agent, and the gold ions and the reducing agent have a molar ratio of 1:0.7 to 1:1.9. The probe may interact with several metal ions of an aqueous solution to produce different changes of fluorescent spectra. Chemical/biochemical molecules can be detected by the fluorescent spectra difference caused by the interaction between the metal ions and the chemical/biochemical molecules.

Abstract: The present disclosure provides a memory. The memory includes an array of memory cells arranged as a plurality of rows by a plurality of columns. A memory cell is connected to at least one redundant memory cell in series in a same row for storing same data as the memory cell; and a column of memory cells correspond to at least one redundant column of redundant memory cells wherein each redundant memory cell in the at least one redundant column stores same data as the memory cell in a same row.