Abstract: Multi-layer moulding having a high structural load-carrying capacity with two opposing broad faces and a laterally peripheral end face, containing, in layers, broad face on broad face, layered wood veneers and, lying between the wood veneers, adhesives. The wood veneers are layered in such a way that the grain of at least one of the wood veneers deviates from the grain of one or the other wood veneers by 45° to 90° and in that the grain of the wood veneers deviates by 22.5 to 67.5° with respect to a surface normal to an end face of the moulding.

Abstract: A monolithic catalyst system for the cleavage of water into hydrogen and oxygen comprises a first photoactive material capable by itself or together with an auxiliary material and/or an auxiliary catalyst when irradiated with light having a wavelength?420 nm of generating oxygen and protons from water, and a second photoactive material capable by itself or together with an auxiliary material and/or an auxiliary catalyst when irradiated with light having a wavelength?420 nm of reducing protons in water to hydrogen. The first and second photoactive materials are in electrical contact via an electron-conducting material.

Abstract: The invention encompasses a novel class of diaryl ether derivatives which inhibit the processing of APP by the putative ?-secretase while sparing Notch signaling pathway, and thus are useful in the treatment or prevention of Alzheimer's disease without the development of Notch inhibition mediated gastrointestinal issues. Pharmaceutical compositions and methods of use are also included.

Abstract: Disclosed are the ERK inhibitors of formula (1): and the pharmaceutically acceptable salts thereof. Also disclosed are methods of treating cancer using the compounds of formula (1).

Abstract: The present invention provides novel pyrimidine amines of formula I which are potent inhibitors of spleen tyrosine kinase, or are prodrugs thereof, and are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD and rheumatoid arthritis and cancer.

Abstract: The invention provides certain 2-pyridyl carboxamide-containing compounds of the Formula (I) or pharmaceutically acceptable salts thereof, wherein A and B are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions mediated by Spleen Tyrosine Kinase (Syk) kinase.

Abstract: The present invention provides novel pyrimidine amines of formula (I) which are potent inhibitors of spleen tyrosine kinase, and are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD and rheumatoid arthritis.

Abstract: The present invention provides novel pyrimidine amines of formula I which are potent inhibitors of spleen tyrosine kinase, and are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD, rheumatoid arthritis and cancer.

Abstract: A pretensioning device (10) for a safety belt, of a motor vehicle, having a gas generator (17), a piston (21) guided in a tube (16), which closes a pressure area (20) in the tube (16) that is pressurized by the gas generator (17) whereupon the piston (21) is able to move in a pretensioning movement which is able to be conveyed to the safety belt by means of an inertia body (19a) resting on a front face (9) of the piston (21). The piston (21) forms a pass-through opening (1) releasable upon exceeding of a predetermined pressure and a recess (26) is provided in the front face (9) with an inertia body (19a) resting thereon, so that a flow connection is created from the pass-through opening (1) to the area (25) located behind the piston (21) in the direction of the pretensioning movement (S).

Abstract: An electrochemical element has a housing having an inside surface, a first electrode resting adjacent an inside surface of the housing and defining a cavity, the first electrode including at least two individual segments adjacent one another in a 2-dimensional manner via first contact surfaces and rest via further contact surfaces adjacent the inside surface, a second electrode of opposite polarity arranged inside the cavity, a separator arranged between the first and second electrodes, and at least one connector arranged between the first contact surfaces which connects the segments electrically conductively and which is annular or ring-shaped and includes at least one strip-shaped projection formed on an outside portion thereof.

Abstract: Stiffened thin-walled natural fibre composite product having first fibre yarns (A), each first fibre having a first thickness, and second fibre yarns (B) having a second thickness larger than the first thickness. At least one side of said product is even. Applications for a seat post; a bicycle saddle; a bicycle frame; a bicycle handle bar; a baseball bat; a piece of furniture; a paddle; or a sheet for automotive applications.

Abstract: According to the invention there is provided a compound of formula I or a pharmaceutically acceptable salt or hydrate thereof; wherein the variables are as defined herein. The compounds selectively attenuate the production of A?42 and hence are useful in treatment of Alzheimer's disease and related conditions.

Abstract: The present invention provides novel pyrimidine amines of formula (I) which are potent inhibitors of spleen tyrosine kinase, and are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD and rheumatoid arthritis.

Abstract: The present invention provides a compound of the Formula I: (Formular I should be inserted here) or a pharmaceutically acceptable salt, solvate or ester thereof, wherein R, R1, R2 and R3 are as defined herein. The compounds are ERK inhibitors. Also disclosed are pharmaceutical compositions comprising the above compounds and methods of treating cancer using the same.

Abstract: An occupant detection system and method are provided for detecting an occupant seated in a vehicle seat. An electrode is arranged in a seat proximate to an expected location of an occupant for sensing an occupant proximate thereto. The electrode may be integrated with a seat heater. Control circuitry controls the seat heater. A signal generator is coupled to the electrode and configured output to the electrode a plurality of signals at a plurality of frequencies. Occupant detection circuitry detects voltages responsive to the plurality of signals at the plurality of frequencies and detects a state of occupancy based on the detected voltages. An LC circuit coupled to the electrode and the control circuitry suppresses capacitance generated by the control circuitry.

Abstract: Multi-layer moulding having a high structural load-carrying capacity with two opposing broad faces and a laterally peripheral end face, containing, in layers, broad face on broad face, layered wood veneers and, lying between the wood veneers, adhesives. The wood veneers are layered in such a way that the grain of at least one of the wood veneers deviates from the grain of one or the other wood veneers by 45° to 90° and in that the grain of the wood veneers deviates by 22.5 to 67.5° with respect to a surface normal to an end face of the moulding.

Abstract: The invention encompasses a novel class of diaryl ether derivatives which inhibit the processing of APP by the putative ?-secretase while sparing Notch signaling pathway, and thus are useful in the treatment or prevention of Alzheimer's disease without the development of Notch inhibition mediated gastrointestinal issues. Pharmaceutical compositions and methods of use are also included.

Abstract: The present invention provides compounds of formula I: or a pharmaceutically acceptable salt thereof. Compounds of formula I are inhibitors of Janus kinases and as such are useful for the treatment of various diseases and conditions mediated by said enzymes, such as rheumatoid arthritis, asthma, COPD, ALS, and the like.

Abstract: A monolithic catalyst system for the cleavage of water into hydrogen and oxygen with the aid of light comprises a first photoactive material capable by itself or together with one or more of an auxiliary material and an auxiliary catalyst of generating oxygen and protons from water, when irradiated with light having a wavelength ?420 nm of generating oxygen and protons from water, and a second photoactive material selected from gallium arsenide, copper indium disulphide/selenide, copper indium gallium disulphide/selenide and cadmium sulphide/selenide/telluride and having a water resistant coating transparent to visible light capable of the reducing protons in water to hydrogen, when irradiated with visible light. The first photoactive material and the second photoactive material are supported on at least one substrate and are in electrical contact, particularly in direct electrical contact, exclusively via one or more electron-conducting materials.

Abstract: A pretensioning device (10) for a safety belt, of a motor vehicle, having a gas generator (17), a piston (21) guided in a tube (16), which closes a pressure area (20) in the tube (16) that is pressurized by the gas generator (17) whereupon the piston (21) is able to move in a pretensioning movement which is able to be conveyed to the safety belt by means of an inertia body (19a) resting on a front face (9) of the piston (21). The piston (21) forms a pass-through opening (1) releasable upon exceeding of a predetermined pressure and a recess (26) is provided in the front face (9) with an inertia body (19a) resting thereon, so that a flow connection is created from the pass-through opening (1) to the area (25) located behind the piston (21) in the direction of the pretensioning movement (S).