Abstract: The present invention provides novel pyrimidine amines of formula (I) which are potent inhibitors of spleen tyrosine kinase, and are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD and rheumatoid arthritis.

Abstract: Described is a monolithic catalyst system (1) for the cleavage of water into hydrogen and oxygen with the aid of light, comprising a first photoactive material (50) capable by itself or together with one or more auxiliary catalysts when irradiated with light having a wavelength ?420 nm of generating oxygen and protons from water, and a second photoactive material (60) capable by itself or together one or more auxiliary catalysts (92) when irradiated with light having a wavelength ?420 nm of reducing protons in water to hydrogen, the first photoactive material (50) and second photoactive material (60) being in electrical contact via one or more electron-conducting materials (30, 20, 40, 60a) the system being in that characterized in that a load or an electric consumer is interposed in between at least one electron-conducting material. Likewise described is a method of generating oxygen, hydrogen and electricity from water using the catalyst system.

Abstract: A tensioning device (10) for a seat belt, in particular in a motor vehicle, having a gas generator (17) and a piston (21) guided in a tube (16) that closes a pressure space (20) in the tube (16), whereas the pressure space (20) can be pressurized by the gas generator (17), as a result of which the piston (21) can be driven to perform a tensioning operation which can be transmitted to the seat belt by means of the force transmission means. The piston (21) having a closed or constricted opening (1, 1a), and the opening (1, 1a) can be enlarged and/or opened by the material erosion caused by the pressure and/or pressure conditions in the pressure space (20).

Abstract: An automated screening device that performs standardized system suitability tests and evaluations and measures components of a submitted sample to assist in the quality control screening of raw materials, ingredients, pharmaceuticals, chemicals, polymers, food products, petroleum and many other materials. After determining the performance suitability of an NMR spectrometer, the system permits samples to be submitted for screening. An NMR spectrum of a sample is acquired and a qualitative analysis unit identifies at least one reference NMR spectrum corresponding a compound present in the sample and a quantitative analysis unit integrates relative signal intensity signals of the sample spectrum in regions of peak intensity in the one reference NMR spectrum and compares integration results to a number of atoms in each region in order to confirm identification of the compound.

Abstract: Compounds of formula I: Selectively attenuate production of A?(1-42) and hence find use in treatment or prevention of diseases associated with deposition of A? in the brain, in particular Alzheimer's disease.

Abstract: A safety belt warning system for vehicles comprises a sensor mat for the detection of a force acting on its surface, which includes, for the formation of two electrical capacitors, two dielectric layers which are located one above the other in sandwich fashion and arranged in each case between electrically conductive coats, and which have different compressibility at least in the direction of loading due to force, so that the capacitances of the two capacitors vary differently with a load on the sensor mat.

Abstract: An electrochemical element has a housing having an inside surface, a first electrode resting adjacent an inside surface of the housing and defining a cavity, the first electrode including at least two individual segments adjacent one another in a 2-dimensional manner via first contact surfaces and rest via further contact surfaces adjacent the inside surface, a second electrode of opposite polarity arranged inside the cavity, a separator arranged between the first and second electrodes, and at least one connector arranged between the first contact surfaces which connects the segments electrically conductively and which is annular or ring-shaped and includes at least one strip-shaped projection formed on an outside portion thereof

Abstract: The invention encompasses 2-[4-(imidazolyl)-phenyl]vinyl-heterocycle derivatives which selectively attenuate production of Abeta(1-42) and are useful in the treatment of Alzheimer's disease. Pharmaceutical compositions and methods of use are also encompassed.

Abstract: According to the invention there is provided a compound of formula I or a pharmaceutically acceptable salt or hydrate thereof; wherein the variables are as defined herein. The compounds selectively attenuate the production of A?42 and hence are useful in treatment of Alzheimer's disease and related conditions.

Abstract: According to the invention there is provided a compound of formula (I): (I) or a pharmaceutically acceptable salt or hydrate thereof; wherein the variables are as defined herein. The compounds selectively attenuate the production of A?42 and hence are useful in treatment of Alzheimer's disease and related conditions.

Abstract: The present invention provides novel pyrimidine amines of formula (I) which are potent inhibitors of spleen tyrosine kinase, and are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD and rheumatoid arthritis.

Abstract: A monolithic catalyst system for the cleavage of water into hydrogen and oxygen comprises a first photoactive material capable by itself or together with an auxiliary material and/or an auxiliary catalyst when irradiated with light having a wavelength ?420 nm of generating oxygen and protons from water, and a second photoactive material capable by itself or together with an auxiliary material and/or an auxiliary catalyst when irradiated with light having a wavelength ?420 nm of reducing protons in water to hydrogen. The first and second photoactive materials are in electrical contact via an electron-conducting material.

Abstract: An occupant detection system and method are provided for detecting an occupant seated in a vehicle seat. An electrode is arranged in a seat proximate to an expected location of an occupant for sensing an occupant proximate thereto. The electrode may be integrated with a seat heater. Control circuitry controls the seat heater. A signal generator is coupled to the electrode and configured output to the electrode a plurality of signals at a plurality of frequencies. Occupant detection circuitry detects voltages responsive to the plurality of signals at the plurality of frequencies and detects a state of occupancy based on the detected voltages. An LC circuit coupled to the electrode and the control circuitry suppresses capacitance generated by the control circuitry.

Abstract: The invention encompasses 2-[4-(imidazolyl)-phenyl]vinyl-heterocycle derivatives which selectively attenuate production of Abeta(1-42) and are useful in the treatment of Alzheimer's disease. Pharmaceutical compositions and methods of use are also encompassed.

Abstract: An air dryer desiccant cartridge, the cartridge comprising a base having an inlet and an outlet, and a casing connected to the base to define a cavity there between, wherein the cavity contains a filter and a desiccant, the filter being arranged upstream of the desiccant such that during normal operation fluid flow entering the cartridge through the inlet passes through the filter and then on to the desiccant before reaching the outlet, and during purging of the cartridge purge flow entering the outlet passes through the desiccant before reaching the filter, wherein further the cartridge includes a valve operable to permit a portion of the purge flow to bypass the filter.

Abstract: Compounds of formula I: Selectively attenuate production of A?(1-42) and hence find use in treatment or prevention of diseases associated with deposition of A? in the brain, in particular Alzheimer's disease.

Abstract: A safety belt warning system for vehicles comprises a sensor mat for the detection of a force acting on its surface, which includes, for the formation of two electrical capacitors, two dielectric layers which are located one above the other in sandwich fashion and arranged in each case between electrically conductive coats, and which have different compressibility at least in the direction of loading due to force, so that the capacitances of the two capacitors vary differently with a load on the sensor mat.

Abstract: A description is given of a process for the production of a disinfectant by electrochemical activation (ECA) of water, in that to the water to be disinfected is added an electrolytic solution, particularly a sodium or potassium chloride solution and the water to which the electrolytic solution has been added in the form of a dilute water/electrolytic solution is supplied with an electrical current in an electrolytic reactor with a cathode compartment having a cathode and with an anode compartment having an anode separated spatially from the cathode compartment by applying a d.c. voltage to the electrodes, in order to bring the water/electrolytic solution into a metastable state suitable for disinfection. To bring about a reliable disinfecting action of the electrochemically activated water and with high reproducibility, the invention proposes that the pH-value of the dilute water/electrolytic solution in the reactor anode compartment is controlled to a value between 2.5 and 3.

Abstract: This invention relates to a door such as a balcony or patio door, featuring a threshold which, to accommodate handicapped traffic, is partly retractable, automatically dropping from its normal base position into its transit position, while by the actuation of a control mechanism it is restorable from the transit position to its normal base position, in a manner whereby in its transit position it permits unimpeded passage for handicapped persons from the inside to the outside and vice versa.

Abstract: The invention refers to a method of resonance spectroscopy for the analysis of statistical properties of samples, comprising the following steps: a) recording of a complex resonance frequency spectrum of each sample by means of phase sensitive quadrature detection; b) numerical differentiation of the recorded complex resonance frequency spectra versus frequency; c) determination of the absolute value of each differentiated complex resonance frequency spectrum (=fingerprint); d) allocation of each fingerprint to a point of a multidimensional point set; and e) performing a pattern analysis of the generated points for characterizing the statistical properties of the samples. The inventive method tolerates unintended variances of measurement in the recorded resonance frequency spectra, in particular caused by phase errors, and allows reliable automated spectral analysis.