Abstract: The present invention relates generally to abuse-deterrent formulations containing dextroamphetamine sulfate.

Abstract: Synthetic nanostructures, proteins that are useful, for example, in making synthetic nanostructures, and methods for designing such synthetic nanostructures are disclosed herein.

Abstract: The present disclosure relates to an apparatus and method for liquid level detection. The method may include providing a circuit board including a plurality of horizontally mounted emitter/receiver pairs arranged vertically along the circuit board within a liquid containment area. The method may further include determining, using one or more processors associated with the circuit board, if liquid is present between each of the plurality of emitter/receiver pairs based upon, at least in part, data received from one or more of the plurality of emitter/receiver pairs.

Abstract: Synthetic nanostructures, polypeptides that are useful, for example, in making synthetic nanostructures, and methods for using such synthetic nanostructures are disclosed herein.

Abstract: Conduit system for conveying fluids is described. The conduit system comprises a conduit, a tubular, and a sealing component. The tubular is positioned radially interior of an inner surface of the conduit along a length. The tubular comprises a polymeric material. The sealing component is positioned proximate the distal end of the tubular in an annulus formed between an outer surface of the tubular and the inner surface of the conduit, the sealing component constructed and arranged to seal the annulus. Methods for reducing corrosion of or providing pressure integrity to a conduit are also described.

Abstract: Synthetic nanostructures, polypeptides that are useful, for example, in making synthetic nanostructures, and methods for using such synthetic nanostructures are disclosed herein.

Abstract: Plasmonically enhanced electric fields are used to deposit particles at selected locations through decomposition or electron transfer reactions with precursor molecules in gas or liquid phase. The location of the enhanced electric fields is controlled through a combination of plasmonic substrate structure shape, material, incident light wavelength and polarization. The particles are deposited at designated locations only, whereby no deposition occurs at locations lacking enhanced electric fields. Many reaction variables can be used to change the rate of particle deposition such as precursor molecules, exposure time, precursor concentration, and temperature making for a highly customizable reaction space.

Abstract: Engineered orthogonal cytokine receptor/ligand pairs, and methods of use thereof, are provided.

Abstract: There is disclosed a self-timed processor. The self-timed processor includes trigger logic having a trigger input to receive an event trigger signal, a data input set to data value 1, a trigger output to send a trigger output signal when the event trigger signal is received, and a reset input to reset the trigger output signal. The processor also has a delay insensitive asynchronous logic (DIAL) block with multi-rail DIAL inputs to receive a multi-rail DIAL input having a) the trigger output signal, and b) data value 0; and data phase completion logic to output a completion signal indicating an end of a data propagate phase of the DIAL block to reset the trigger output signal when multi-rail data DIAL data process values of the DIAL block reach a DIAL valid state.

Abstract: Described herein are polypeptides capable of self-assembling to form homo-oligomers, and methods for designing such polypeptides.

Abstract: The invention provides compositions and methods for treating celiac sprue.

Abstract: Methods and apparatus for identifying and screening hydrogen bond networks are provided. A computing device can determine a search space for hydrogen bond networks related to one or more molecules, where the search space can include a plurality of energy terms related to a plurality of residues related to the hydrogen bond networks. The computing device can search the search space to identify one or more hydrogen bond networks based on the plurality of energy terms. The computing device can screen the identified hydrogen bond networks to identity one or more screened hydrogen bond networks based on scores for the identified hydrogen bond networks. An output can be generated that is related to the one or more screened hydrogen bond networks. Also provided are polypeptides that can form homo-oligomers with modular hydrogen bond network-mediated specificity.

Abstract: Synthetic nanostructures, proteins that are useful, for example, in making synthetic nanostructures, and methods for designing such synthetic nanostructures are disclosed herein.

Abstract: There is disclosed a self-timed processor. The self-timed processor includes trigger logic having a trigger input to receive an event trigger signal, a data input set to data value 1, a trigger output to send a trigger output signal when the event trigger signal is received, and a reset input to reset the trigger output signal. The processor also has a delay insensitive asynchronous logic (DIAL) block with multi-rail DIAL inputs to receive a multi-rail DIAL input having a) the trigger output signal, and b) data value 0; and data phase completion logic to output a completion signal indicating an end of a data propagate phase of the DIAL block to reset the trigger output signal when multi-rail data DIAL data process values of the DIAL block reach a DIAL valid state.

Abstract: A genetically modified polypeptide is disclosed which comprises an amino acid sequence of phosphotriesterase (PTE) having at least twice the catalytic efficiency for a V-type nerve agent as a polypeptide which consists of the sequence as set forth in SEQ ID NO: 1, when assayed under identical conditions.

Abstract: Disclosed herein are compositions and methods for treating celiac sprue.

Abstract: The present invention relates generally to abuse-deterrent formulations containing dextroamphetamine sulfate.

Abstract: 2-ketoacid decarboxylase enzymes, compositions encoding for 2 ketoacid decarboxylase enzymes, and host cells comprising such enzymes or compositions are provided

Abstract: Methods and systems for designing proteins are disclosed, as well as proteins and protein assemblies designed. A comparing device can determine a protein repeating unit that includes one or more protein helices and one or more protein loops. The computing device can generate a protein backbone structure with a copy of the protein repeating unit. The computing device can determine whether a distance between a pair of helices of the protein backbone structure is between lower and upper distance thresholds. After determining that the distance between the pair of helices is between the lower and upper distance thresholds, the computing device can generate a plurality of protein sequences based on the protein backbone structure, select a particular protein sequence of the plurality of protein sequences based on an energy landscape that has information about energy and distance from a target fold of the particular protein sequence, and generate an output based on the particular protein sequence.

Abstract: Aircraft gas turbine engine spinner includes conical forward spinner section extending aftwardly from spinner tip to a curved aft spinner section circumscribed about centerline axis, a spinner aspect ratio greater than about 1.8, and wherein spinner aspect ratio is an axial distance between spinner tip and spinner end divided by radial distance from axis to spinner end. Aspect ratio may be in a range of about 2.0-2.2 or about 2.2-2.8. Aft spinner section may be substantially tangential to platform leading edges of platforms of fan blades. Aft spinner section may have cambered or an elliptical axially curved cross-section. Spinner axial cross-section may have longer spinner axial distance compared to baseline axial distance of baseline cross-section and spinner aspect ratio greater than baseline aspect ratio of baseline cross-section.