Abstract: A method comprising: receiving a radio map of an indoor venue using survey data collected by a survey device positioned throughout the venue, the radio map including a boundary; receiving harvest data from a mobile device, wherein at least some of the harvest data are obtained by the mobile device while the mobile device is positioned at locations that are outside of the boundary; determining, based on the harvest data, a trajectory of the mobile device, wherein at least some of the trajectory resides outside of the boundary; identifying one or more locations on or proximate to the trajectory; and extending the radio map using the survey data and the one or more identified locations, wherein the extended radio map is defined at least in part by an extension of the boundary to encompass the one or more identified locations.

Abstract: Various embodiments include methods and apparatus structured to increase efficiencies of a drilling operation. These efficiencies may be realized with a fiber cable located in a wellbore at a well site, where the fiber cable can include an optical fiber disposed as a single handed helix in the fiber cable, where the optical fiber is disposed in the cable without having helix hand reversal. Construction of such fiber cables may include applying a twist to the optical fiber during insertion of the optical fiber into the fiber cable in a tubing process in which control of an amount of the twist to form a portion of the optical fiber can control excess fiber length in the tube. Additional apparatus, systems, and methods can be implemented in a variety of applications.

Abstract: The invention provides for systems, methods, and compositions for targeting nucleic acids. In particular, the invention provides non-naturally occurring or engineered RNA-targeting systems comprising a novel RNA-targeting CRISPR effector protein and at least one targeting nucleic acid component like a guide RNA.

Abstract: A cable for use in a wellbore can include an outer housing and a chamber disposed coaxially within the outer housing. The chamber can have a cross-sectional end length that is substantially the same as an inner diameter of the outer housing. The cable can also include a fiber optic cable disposed in a nonlinear arrangement within the chamber. The cable can also include a conductor disposed adjacent to the chamber within the outer housing. The conductor can be usable for transmitting power to a well tool.

Abstract: A treatment system includes a guide sheath, and a catheter provided with a pressure-controlled element. The pressure-control element preferably includes an expanded configuration adapted to extend across a small feeder vessel branching from the splenic vein. The pressure-control element is positioned with the feeder vessel, and a therapeutic agent is delivered under pressure directly into the feeder vessel, where it is forced to penetrate deep into tissue. Pressure responsive elements for monitoring intravascular pressure are also provided to time delivery of the therapeutic agent for maximum uptake by the target organ.

Abstract: The disclosure provides for systems, methods, and compositions for targeting and editing nucleic acids. In particular, the invention provides non-naturally occurring or engineered RNA-targeting systems comprising a RNA-targeting Cas13 protein, at least one guide molecule, and at least one adenosine deaminase protein or catalytic domain thereof.

Abstract: The invention provides for systems, methods, and compositions for targeting and editing nucleic acids. In particular, the invention provides non-naturally occurring or engineered DNA-targeting systems comprising a DNA-targeting Cpf1 protein, at least one guide molecule, and at least one adenosine deaminase protein or catalytic domain thereof.

Abstract: Methods, program products, and systems for using multiple sensors to determine a location fingerprint are described. A sampling device can measure RF signals detected at a train station of a transit system or a route of the transit system. The sampling device, or a location server receiving the measurements, can filter RF signal measurements using one or more readings from sensors coupled to the sampling device and that are different from RF receivers. The readings can be taken concurrently with the RF signal measurements. These readings, designated as motion cues, can include motion sensor readings, barometer readings, or magnetometer readings. Using the motion cues, the sampling device or location server can distinguish different platforms of a station of the transit system and different levels of the station, or filter out RF signal measurements that may have been inaccurate, e.g., as caused by disturbances from a train entering or leaving a station.

Abstract: A device for mounting an electrical energy source in portable electronic equipment is provided, including a cavity and a cover configured to close the cavity, the cover including a housing configured to receive the energy source, the cover and the portable electronic equipment having complementary fixing means in order to retain the cover on the portable electronic equipment and to seal the cavity, and the cover including means for retaining the energy source in the housing of the cover.

Abstract: Systems with pressure-responsive elements for monitoring intravascular pressure are also provided to time delivery of the therapeutic agent for maximum uptake by the target organ. Methods for treating tissues and organs via vascular pathways are provided.

Abstract: Systems and methods relating to monitoring cargo are provided. Various embodiments provide features relating to: (1) monitoring characteristics of cargo using a single device that may be disposable; (2) generating alerts based on a variety of temperature conditions, such as multiple temperature thresholds; (3) providing multiple levels of alerts and escalating alerts to different users; (4) providing an indication of an end of trip based on location data and data from sensor(s); (5) reducing power of transmissions between devices; (6) using frequency diversity features to communicate between devices; (7) providing configurable reporting and/or sensor monitoring parameters, and changing reporting and/or sensor measurement periods; (8) allowing for communication with devices across multiple frequency bands; (9) utilizing secondary communication circuits to communicate with different devices, such as across different frequency channels and/or bands; and (10) using a movement detection device (e.g.

Abstract: The present disclosure provides systems and methods that perform face reconstruction based on an image of a face. In particular, one example system of the present disclosure combines a machine-learned image recognition model with a face modeler that uses a morphable model of a human's facial appearance. The image recognition model can be a deep learning model that generates an embedding in response to receipt of an image (e.g., an uncontrolled image of a face). The example system can further include a small, lightweight, translation model structurally positioned between the image recognition model and the face modeler. The translation model can be a machine-learned model that is trained to receive the embedding generated by the image recognition model and, in response, output a plurality of facial modeling parameter values usable by the face modeler to generate a model of the face.

Abstract: The invention provides for systems, methods, and compositions for targeting and editing nucleic acids. In particular, the invention provides non-naturally occurring or engineered RNA-targeting systems comprising a RNA-targeting Cas13 protein, at least one guide molecule, and at least one cytidine deaminase protein or catalytic domain thereof.

Abstract: Techniques for broadcasting notifications with low latency are provided. A set of recipients for a notification of a content item is determined. The notification is stored in a second notifications storage that is separate from a first notifications storage. A request for one or more notifications is received over a computer network from a client device that is associated with a particular recipient in the set of recipients. In response to receiving the request, first notification data is retrieved from the first notifications storage, second notification data that includes the notification is retrieved from the second notifications storage. The first notification data is combined with the second notification data to generate combined notification data. The combined notification data is transmitted over the computer network to the client device and is stored in the first notifications storage. The notification may be removed from the first notifications storage.

Abstract: A computer-implemented method for space frame design involves constructing a load stress map in a geometrical boundary representation of a design space, defining attachment points and load application points in the design space, creating a starting network of interconnecting lines between each two of the attachment points and load application points in the design space, assigning load application factors to each line of the starting network of interconnecting lines based on values of the load stress map, generating potential space frame designs by culling different subsets of lines of the starting network of interconnecting lines for each potential space frame design according to variable culling parameters, evaluating the potential space frame designs with respect to optimization parameters, combining the culling parameters for the potential space frame designs the performance score of which is above a predefined performance threshold, and iterating the steps of generating potential space frame designs and e

Abstract: A gas lift pump apparatus for treating ballast water includes a column through which a liquid medium, such as seawater, may be pumped by gas lift. The apparatus includes a delivery device for delivering a flow of a gas into the liquid medium, and a resonance chamber that generates ultrasonic energy therein by the flow of the gas therethrough. The apparatus is operable to launch the ultrasonic energy into the liquid medium in the column.

Abstract: A firearm accessory mount is an apparatus that maximizes the mounting surfaces on a firearm while allowing the interchangeability of a barrel onto and off of the firearm. The apparatus includes a left tactical rail, a right tactical rail, a gas-cylinder clamp, an upper tactical rail, and an elongated fixture with a transversal arc-shaped cross section. The left tactical rail, the right tactical rail, and the upper tactical rail allows for a variety of firearm accessories to mount onto the apparatus. The gas-cylinder clamp attaches the apparatus onto the gas cylinder. The elongated fixture braces the barrel while attached to the firearm. The arc-shaped cross-section of the elongated fixture allows the barrel to be replaced or a new barrel to be attached without altering the position and orientation of the firearm. The apparatus further includes a lower tactical rail that allows the mounting of firearm accessories beneath the gas cylinder.

Abstract: Disclosed in some examples are methods, systems, computing devices, and machine readable mediums that provide for cropping systems that automatically crop digital images using one or more smart cropping techniques. Smart cropping techniques may include: cropping an image based upon emotion detection, cropping based upon facial recognition and matching, and cropping based upon landmark matching. In some examples, a single smart cropping technique may be utilized. In other examples, a combination of the smart cropping techniques may be utilized.

Abstract: A design engine for designing an object using structural analysis. The design engine generates a lattice structure for the object comprising a plurality of nodes and a plurality of lines connecting the nodes. The lattice structure is optimized to remove one or more lines using structural analysis based on at least one load-related design requirement. Several design options are provided for generating and optimizing the lattice structure. The design engine then generates a 3D model of the object by thickening each line of the lattice structure into a pipe volume. The thickness of each pipe is determined using structural analysis based on the at least one load-related design requirement. The 3D model represents the volume of the object and is exportable to a fabrication device.

Abstract: An endovascular microvalve device for use in a vessel during a therapy procedure includes a catheter and a filter valve coupled to the catheters. The filter valve is dynamically reconfigurable to automatically block and permit fluid flow through a vessel based on a local fluid pressure conditions about the filter valve. In embodiments, the filter valve has a proximal end fixed to the catheter, and a distal end which may be movable over the catheter. The lumen of the inner catheter delivers a therapeutic agent beyond the valve. The device is used to provide a therapy in which a therapeutic agent is infused into an organ.