Abstract: A method executed by a computing device includes obtaining a string of words and determining whether two or more words of the string of words are in a word group. When the two or more words are in the word group, the method further includes determining a set of identigens for each word of the word group to produce sets of identigens, where a set of identigens of the sets of identigens represents one or more different meanings of a word of the word group. The method further includes interpreting, using identigen pairing rules, the sets of identigens to produce an entigen group. The method further includes assigning a new entigen to represent the entigen group, where the new entigen represents a most likely meaning interpretation of the word group.

Abstract: Disclosed herein are methods of treating a subject with rheumatoid arthritis (RA) and methods of predicting the subject's likelihood of responding to a new RA therapy. The methods include administering to the subject a composition comprising a macrophage targeting construct and an imaging moiety conjugated thereto to acquiring planar images of a plurality of joints of the subject, and determining at least one TUVGlobal value for the subject from the planar images. Covariates comprising the quantification of serological RA markers and/or clinical assessments may be further obtained to apply statistical modeling to the combination of the at least one TUVGlobal and the one or more covariates. The statistical modeling is used to determine a likelihood of response to an RA therapy, and a treatment is administered to the subject based on the likelihood of response to the RA therapy.

Abstract: Disclosed are methods and compositions for repolarizing a tumor associated macrophage (TAM) from M2 to M1 comprising administering to a subject in need thereof an effective dose of a compound comprising a dextran backbone and one or more CD206 targeting moieties conjugated thereto. In certain aspects, the compound further comprises a therapeutic agent selected from: paclitaxel, gemcitabine, lapatinib, and doxorubicin. In further aspect, the therapeutic agent comprises a chelator and at least one metal ion. In certain implementations, the at least one metal ion comprises at least one Cu(II) ions.

Abstract: A method for execution by a computing device includes obtaining a phrase that includes string of words and generating a valid sequence of words utilizing the phrase. The method further includes identifying a set of identigens for each word of the valid sequence of words to produce sets of identigens. The method further includes identifying, for each identigen of the sets of identigens, a word type associated with phrase structure grammar rules to produce sets of identigen-type associations. The method further includes interpreting, utilizing the phrase structure grammar rules, the sets of identigen-type associations to produce an entigen group. The entigen group represents a most likely interpretation of the phrase.

Abstract: A method performed by a computing device includes generating a comparative query entigen group set based on a comparative query in accordance with identigen rules, where the comparative query entigen group set represents a most likely interpretation of the comparative query. The method further includes obtaining a first response entigen group from a knowledge database based on a first comparative query entigen group of the comparative query entigen group set, where the first response entigen group substantially includes the first comparative query entigen group. The method further includes obtaining a second response entigen group from the knowledge database based on a second comparative query entigen group of the comparative query entigen group set, where the second response entigen group substantially includes the second comparative query entigen group. The method further includes generating a comparative response based on the first response entigen group and the second response entigen group.

Abstract: A method performed by a computing device includes determining a set of identigens for each word of a query of a topic to produce sets of identigens. Each set of identigens represents one or more different meanings of a word of the query. The method further includes interpreting, using identigen pairing rules, the sets of identigens to determine a most likely meaning interpretation of the query and produce an excluding query entigen group with an excluding entigen. The method further includes recovering a response entigen group for the query from a knowledge database utilizing the excluding query entigen group. The response entigen group provides a response to the query.

Abstract: A method performed by a computing device includes determining a set of identigens for each word of words of a product-service query to produce sets of identigens. The method further includes interpreting, using identigen pairing rules of a knowledge database, the sets of identigens to determine a most likely meaning interpretation of the product-service query and produce a query entigen group that includes query entigens. The method further includes identifying one or more characteristic entigen categories for a subjective category entigen of the query entigen group. The method further includes recovering a set of response entigens for the product-service query from the knowledge database utilizing the query entigen group and based on the one or more characteristic entigen categories. The set of response entigens provides an answer for the product-service query.

Abstract: A method performed by a computing device includes obtaining a set of image segment identigens for image segments of an image to produce sets of image segment identigens. A set of image segment identigens is a set of possible interpretations of a first image segment of the image segments. The method further includes identifying a subset of valid image segment identigens of each set of image segment identigens by applying identigen rules to the sets of image segment identigens to produce subsets of valid image segment identigens. Each valid image segment identigen of a subset of valid image segment identigens represents a most likely interpretation of a corresponding image segment. The method further includes generating an image entigen group utilizing the subsets of valid image segment identigens, where the image entigen group represents a most likely interpretation of the image.

Abstract: A system for simultaneously producing immersive visual effects on an inside of an enclosure and passive visual effects to be viewed from the outside of the enclosure. The enclosure includes a plurality of sidewalls each having a reflective inner surface facing one other. The system includes a digital video display positioned to direct digital video imagery through the semi-reflective sidewall and into the enclosure. Light of the digital video imagery reflects off the reflective inner surfaces of plurality of sidewalls, which allow a percentage of the light to leave the enclosure, making the visual effects observable from the outside. The light will continue this cycle of reflection and transmission, creating an observable infinity effect from the outside, and an entirely enclosed visual experience from the inside.

Abstract: A continuous serpentine concrete beamway forming system and method for creating a hollow continuous serpentine concrete beamway are disclosed. The continuous serpentine concrete beamway forming system and method utilizes a flexible form material that has the ability to conform to curves, angles, and slopes of a target beamway system as intended. The flexible form material is used to form an armature that embodies a precise pathway of the target beamway system. The armature is contiguous throughout a plurality of connected beamway segments that collectively make up the target beamway system and that are precisely aligned to conform to the curves, angles, and slopes of the target beamway system. A part of the armature creates grooves on the surfaces of the connected beamway segments. The grooves are subsequently used to guide machinery that grinds the running surfaces to precise tolerances.

Abstract: A method performed by a computing device includes determining a set of identigens for each word of words of a subjective query to produce sets of identigens. The method further includes interpreting, using identigen pairing rules of a knowledge database, the sets of identigens to determine a most likely meaning interpretation of the subjective query and produce a query entigen group that includes query entigens. The method further includes identifying one or more characteristic entigen categories for a subjective category entigen of the query entigen group. The method further includes recovering a set of response entigens for the subjective query from the knowledge database utilizing the query entigen group and based on the one or more characteristic entigen categories. The set of response entigens provides an answer for the subjective query.

Abstract: A method performed by a computing device includes obtaining impaired content for a topic that includes a series of words, and determining a set of identigens for each word of the series of words to produce sets of identigens. The method further includes interpreting, using identigen pairing rules of a knowledge database, the sets of identigens to determine a most likely meaning interpretation of the impaired content and produce an interim entigen group. The method further includes recovering an improved entigen group for the topic from the knowledge database utilizing the interim entigen group and based on a knowledge defect of the interim entigen group caused by an impairment of the impaired content.

Abstract: A method includes generating a plurality of entigen groups from a plurality of phrases, where the plurality of entigen groups represents a plurality of most likely meanings for the plurality of phrases. The method further includes determining an initial interpretation of the related topic based on the plurality of most likely meanings for the plurality of phrases and generating a plurality of scores for the plurality of entigen groups based on the initial interpretation and source information of the plurality of phrases. The method further includes interpreting the plurality of scores in relation to the initial interpretation to determine a confidence level of the initial interpretation and when the confidence level of the initial interpretation compares favorably to a confidence threshold, indicating that the initial interpretation is reliable.

Abstract: A method performed by a computing device includes identifying a first set of sentiment identigens of a plurality of sets of identigens for a query that includes a string of words, where the first set of sentiment identigens represents different meanings of a first sentiment word of the string of words. The method further includes selecting an entigen group from a knowledge database based on the plurality of sets of identigens, where a first sentiment entigen of the entigen group corresponds to the first set of sentiment identigens. The method further includes generating a response entigen group based on the entigen group, where a response entigen of the response entigen group corresponds to a selected identigen from a set of identigens of the plurality of sets of identigens regarding a word of the string of words.

Abstract: A method includes determining a set of identigens for words of content to produce a sets of identigens and interpreting the sets of identigens to determine a most likely meaning interpretation of the content and produce a baseline entigen group. The method further includes recovering an incomplete entigen group for the topic from a first knowledge database based on a knowledge defect of the incomplete entigen group with regards to the topic. The method further includes obtaining an additive entigen group from a second knowledge database based on the knowledge defect and modifying the incomplete entigen group utilizing the additive entigen group to produce an updated entigen group to provide a beneficial cure for the knowledge defect of the incomplete entigen group.

Abstract: A method includes detecting an incomplete entigen group within a knowledge database. The incomplete entigen group includes entigens and one or more entigen relationships between at least some of the entigens. The incomplete entigen group represents knowledge of a topic. The method further includes obtaining additive content for the topic based on the incomplete entigen group and generating an additive entigen group based on the additive content. The method further includes updating the incomplete entigen group utilizing the additive entigen group to produce an updated entigen group. The method further includes indicating that the updated entigen group has an un-curated status when the additive entigen group conflicts with the incomplete entigen group.

Abstract: A method performed by a computing device includes generating a first aptitude level entigen group for a first aptitude level phrase in accordance with identigen rules. The first aptitude level entigen group represents a most likely interpretation of the first aptitude level phrase. The method further includes obtaining a multiple aptitude level entigen group from a knowledge database based on the first aptitude level entigen group. The multiple aptitude level entigen group includes the first aptitude level entigen group. The method further includes generating a second aptitude level entigen group utilizing the multiple aptitude level entigen group. The method further includes generating a second aptitude level phrase based on the second aptitude level entigen group. The second aptitude level entigen group represents a most likely interpretation of the second aptitude level phrase.

Abstract: A method executed by a computing device includes determining to update an entigen group within a knowledge database, where the entigen group includes a set of linked entigens that represent knowledge associated with an object. The method further includes determining a set of identigens for each word of a phrase associated with the object to produce sets of identigens. The method further includes interpreting the sets of identigens to determine a most likely meaning interpretation of the phrase and produce a new entigen group. The method further includes updating the entigen group utilizing the new entigen group to produce a curated entigen group such that a deficiency of the entigen group is resolved providing more accurate and more complete knowledge of the object.

Abstract: A method includes obtaining a string of words and determining whether two or more words of the string of words are in a word group. When the two or more words are in the word group, the method further includes retrieving a set of word group identigens for the word group and retrieving sets of word identigens for remaining words of the string of words. The method further includes determining whether a word group identigen of the set of word group identigens and word identigens of the sets of word identigens creates an entigen group that is a valid interpretation of the string of words. When the entigen group is the valid interpretation of the string of words, the method further includes outputting the entigen group.

Abstract: A method includes detecting a defective entigen group within a knowledge database. The defective entigen group includes entigens and one or more entigen relationships between at least some of the entigens. The defective entigen group represents knowledge of a topic. The method further includes obtaining corrective content for the topic based on the defective entigen group and generating a corrective entigen group based on the corrective content. The method further includes updating the defective entigen group utilizing the corrective entigen group to produce a curated entigen group.