Patents by Inventor David Ralph

David Ralph has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200242137
    Abstract: A method performed by a computing device includes generating a first aptitude level entigen group for a first aptitude level phrase in accordance with identigen rules. The first aptitude level entigen group represents a most likely interpretation of the first aptitude level phrase. The method further includes obtaining a multiple aptitude level entigen group from a knowledge database based on the first aptitude level entigen group. The multiple aptitude level entigen group includes the first aptitude level entigen group. The method further includes generating a second aptitude level entigen group utilizing the multiple aptitude level entigen group. The method further includes generating a second aptitude level phrase based on the second aptitude level entigen group. The second aptitude level entigen group represents a most likely interpretation of the second aptitude level phrase.
    Type: Application
    Filed: January 8, 2020
    Publication date: July 30, 2020
    Applicant: entigenlogic LLC
    Inventors: Frank John Williams, David Ralph Lazzara, Stephen Emerson Sundberg, Ameeta Vasant Reed, Dennis Arlen Roberson, Thomas James MacTavish, Karl Olaf Knutson, Jessy Thomas, Niklas Josiah MacTavish, David Michael Corns, II, Andrew Chu, Theodore Mazurkiewicz, Gary W. Grube
  • Publication number: 20200237937
    Abstract: Compositions and methods are disclosed for assessing macrophage involvement in the inflammation of one or more joints of a subject. In certain aspects, the disclosed method includes the steps of administering to the subject a composition comprising a mannosylated dextran construct with an imaging moiety conjugated thereto; acquiring one or more planar images of a first joint of the subject; defining a region of interest (ROI) comprising the first joint; defining a joint specific reference region (RR); determining a MARTAD value of the joint by assessing the ratio of average pixel intensity of the ROI to the average pixel intensity of the RR; and comparing the MARTAD of the first joint to a normal MARTAD value for a corresponding joint, and wherein macrophage involvement is indicated by a joint specific MARTAD value that exceeds the normal MARTAD value by a predetermined threshold.
    Type: Application
    Filed: January 27, 2020
    Publication date: July 30, 2020
    Inventors: David A. Ralph, Michael Rosol, Ahmad Ismail, Allison Kissling, Frederick O. Cope, Bonnie Chandler Abbruzzese
  • Publication number: 20200210643
    Abstract: A method performed by a computing device includes identifying a first set of sentiment identigens of a plurality of sets of identigens for a query that includes a string of words, where the first set of sentiment identigens represents different meanings of a first sentiment word of the string of words. The method further includes selecting an entigen group from a knowledge database based on the plurality of sets of identigens, where a first sentiment entigen of the entigen group corresponds to the first set of sentiment identigens. The method further includes generating a response entigen group based on the entigen group, where a response entigen of the response entigen group corresponds to a selected identigen from a set of identigens of the plurality of sets of identigens regarding a word of the string of words.
    Type: Application
    Filed: December 11, 2019
    Publication date: July 2, 2020
    Applicant: entigenlogic LLC
    Inventors: Frank John Williams, David Ralph Lazzara, Stephen Emerson Sundberg, Ameeta Vasant Reed, Dennis Arlen Roberson, Thomas James MacTavish, Karl Olaf Knutson, Jessy Thomas, Niklas Josiah MacTavish, David Michael Corns, II, Andrew Chu, Theodore Mazurkiewicz, Gary W. Grube
  • Publication number: 20200175064
    Abstract: A method performed by a computing device includes obtaining a set of image segment identigens for image segments of an image to produce sets of image segment identigens. A set of image segment identigens is a set of possible interpretations of a first image segment of the image segments. The method further includes identifying a subset of valid image segment identigens of each set of image segment identigens by applying identigen rules to the sets of image segment identigens to produce subsets of valid image segment identigens. Each valid image segment identigen of a subset of valid image segment identigens represents a most likely interpretation of a corresponding image segment. The method further includes generating an image entigen group utilizing the subsets of valid image segment identigens, where the image entigen group represents a most likely interpretation of the image.
    Type: Application
    Filed: November 26, 2019
    Publication date: June 4, 2020
    Applicant: entigenlogic LLC
    Inventors: Frank John Williams, David Ralph Lazzara, Stephen Emerson Sundberg, Ameeta Vasant Reed, Dennis Arlen Roberson, Thomas James MacTavish, Karl Olaf Knutson, Jessy Thomas, Niklas Josiah MacTavish, David Michael Corns, II, Andrew Chu, Theodore Mazurkiewicz, Gary W. Grube
  • Publication number: 20200134481
    Abstract: A method includes detecting a defective entigen group within a knowledge database. The defective entigen group includes entigens and one or more entigen relationships between at least some of the entigens. The defective entigen group represents knowledge of a topic. The method further includes obtaining corrective content for the topic based on the defective entigen group and generating a corrective entigen group based on the corrective content. The method further includes updating the defective entigen group utilizing the corrective entigen group to produce a curated entigen group.
    Type: Application
    Filed: October 10, 2019
    Publication date: April 30, 2020
    Applicant: entigenlogic LLC
    Inventors: Frank John Williams, David Ralph Lazzara, Donald Joseph Wurzel, Paige Kristen Thompson, Stephen Emerson Sundberg, Ameeta Vasant Reed, Stephen Chen, Dennis Arlen Roberson, Thomas James MacTavish, Karl Olaf Knutson, Jessy Thomas, David Michael Corns, II, Andrew Chu, Theodore Mazurkiewicz, Gary W. Grube
  • Publication number: 20200108069
    Abstract: This invention relates to the treatment of fibrotic conditions, such as Peyronie's disease, by administering a phosphodiesterase type 5 (PDE5) inhibitor, such as vardenafil, and a selective oestrogen receptor modulator (SERM), such as tamoxifen, to an individual in need thereof.
    Type: Application
    Filed: September 19, 2019
    Publication date: April 9, 2020
    Inventors: Selim CELLEK, Marcus ILG, David RALPH, Asif MUNEER, Marta MATEUS, William STEBBEDS
  • Publication number: 20200097547
    Abstract: A method includes identifying a set of identigens for each word of a first phrase of a phrase group to produce a first plurality of sets of identigens and determining whether first and second identigen rules are applicable to the first plurality of sets of identigens. When the first and second identigen rules are applicable to the first plurality of sets of identigens, the method further includes identifying a set of identigens for each word of a second phrase of the phrase group to produce a second plurality of sets of identigens and determining that the first identigen rules are applicable to the second plurality of sets of identigens. The method further includes identifying one valid identigen of each set of identigens of the first plurality of sets of identigens by applying the first identigen rules to the first plurality of sets of identigens to produce a first entigen group.
    Type: Application
    Filed: September 17, 2019
    Publication date: March 26, 2020
    Applicant: entigenlogic LLC
    Inventors: Frank John Williams, David Ralph Lazzara, Dennis Arlen Roberson, Stephen Emerson Sundberg, Stephen Chen, Karl Olaf Knutson, Jessy Thomas, David Michael Corns, II, Andrew Chu, Gary W. Grube
  • Patent number: 10584448
    Abstract: A continuous serpentine concrete beamway forming system and method for creating a hollow continuous serpentine concrete beamway are disclosed. The continuous serpentine concrete beamway forming system and method utilizes a flexible form material that has the ability to conform to curves, angles, and slopes of a target beamway system as intended. The flexible form material is used to form an armature that embodies a precise pathway of the target beamway system. The armature is contiguous throughout a plurality of connected beamway segments that collectively make up the target beamway system and that are precisely aligned to conform to the curves, angles, and slopes of the target beamway system. A part of the armature creates grooves on the surfaces of the connected beamway segments. The grooves are subsequently used to guide machinery that grinds the running surfaces to precise tolerances.
    Type: Grant
    Filed: March 19, 2018
    Date of Patent: March 10, 2020
    Inventor: David Ralph Ward
  • Publication number: 20200034358
    Abstract: A method includes generating an initial entigen group for a query from existing entigens in a knowledge database and determining whether the initial entigen group provides a reliable response to the query. When the initial entigen group does not provide a reliable response to the query, the method further includes determining a desired entigen to add to the initial entigen group to produce an updated entigen group that leads to the reliable response to the query and creating the desired entigen based on obtained targeted data. The method further includes adding the desired entigen to the initial entigen group to produce the updated entigen group and determining whether the updated entigen group provides the reliable response to the query. When the updated entigen group provides the reliable response to the query, the method further includes outputting the reliable response.
    Type: Application
    Filed: July 25, 2019
    Publication date: January 30, 2020
    Applicant: entigenlogic LLC
    Inventors: Donald Joseph Wurzel, Frank John Williams, David Ralph Lazzara, Stephen Chen, Dennis Arlen Roberson, Andrew Chu, Gary W. Grube
  • Publication number: 20200004738
    Abstract: A method includes obtaining an initial answer entigen group from a knowledge database based on a query entigen group of a query. The method further includes determining that a reliable and definitive answer for the query is not obtainable from the initial answer entigen group. When an incomplete answer entigen is a cause for the inability to obtain the reliable and definitive answer, the method further includes determining a missing element, obtaining data regarding the missing element, updating the incomplete answer entigen with the data to produce an updated answer entigen, and updating the initial answer entigen group with the updated answer entigen to produce an updated answer entigen group. When the updated answer entigen group produces the reliable and definitive answer, the method further includes outputting the reliable and definitive answer.
    Type: Application
    Filed: June 27, 2019
    Publication date: January 2, 2020
    Applicant: entigenlogic LLC
    Inventors: Frank John Williams, David Ralph Lazzara, Stephen Chen, Karl Olaf Knutson, Jessy Thomas, David Michael Corns, II, Andrew Chu, Gary W. Grube
  • Publication number: 20190362145
    Abstract: A method includes obtaining a set of image segment identigens for each image segment of an image to produce sets of image segment identigens. The sets of image segment identigens are possible interpretations of an image segment. The method further includes generating a set of relationships between image segments. The relationships provide a list of one or more ways in which the image segments are related. The method further includes processing different permutations of the sets of image segment identigens in accordance with the set of relationships to generate an entigen group. The entigen group represents a most likely interpretation of the image.
    Type: Application
    Filed: May 20, 2019
    Publication date: November 28, 2019
    Applicant: entigenlogic LLC
    Inventors: Frank John Williams, David Ralph Lazzara, Stephen Chen, Karl Olaf Knutson, Jessy Thomas, David Michael Corns, II, Andrew Chu, Gary W. Grube
  • Patent number: 10477320
    Abstract: Disclosed herein are speaker assemblies and acoustic devices comprising a panel having a long side and a short side, at least one transducer configured to excite the panel at a plurality of excitation locations on the panel to generate a wave having a wave front substantially perpendicular to the long side and propagating toward the short side of the panel and, optionally, at least one attenuating component mounted to the panel. Methods for generating an acoustic sound are also disclosed herein.
    Type: Grant
    Filed: September 16, 2015
    Date of Patent: November 12, 2019
    Assignee: CORNING INCORPORATED
    Inventors: Dmitri Vladislavovich Kuksenkov, David Ralph Maack, Zhiqiang Shi
  • Publication number: 20190325027
    Abstract: A method includes obtaining a string of words and determining whether two or more words of the string of words are in a word group. When the two or more words are in the word group, the method further includes retrieving a set of word group identigens for the word group and retrieving sets of word identigens for remaining words of the string of words. The method further includes determining whether a word group identigen of the set of word group identigens and word identigens of the sets of word identigens creates an entigen group that is a valid interpretation of the string of words. When the entigen group is the valid interpretation of the string of words, the method further includes outputting the entigen group.
    Type: Application
    Filed: April 16, 2019
    Publication date: October 24, 2019
    Applicant: entigenlogic LLC
    Inventors: Frank John Williams, David Ralph Lazzara, Donald Joseph Wurzel, Paige Kristen Thompson, Stephen Emerson Sundberg, Stephen Chen, Karl Olaf Knutson, Jessy Thomas, David Michael Corns, II, Andrew Chu, Eric Andrew Faurie, Theodore Mazurkiewicz, Gary W. Grube
  • Publication number: 20190325022
    Abstract: A method includes generating a new entigen group regarding trusted new information. The method further includes generating entigen groups from phrases of a document and determining whether an entigen group of the entigen groups has a most likely meaning similar to a most likely meaning of the new entigen group. When the entigen group has a most likely meaning similar to the most likely meaning of the new entigen group, the method further includes updating the entigen group based on the new entigen group. When the entigen groups do not include an entigen group having a most likely meaning similar to the most likely meaning of the new entigen group, the method further includes updating the entigen groups to include the new entigen group.
    Type: Application
    Filed: April 16, 2019
    Publication date: October 24, 2019
    Applicant: entigenlogic LLC
    Inventors: Frank John Williams, David Ralph Lazzara, Donald Joseph Wurzel, Paige Kristen Thompson, Stephen Emerson Sundberg, Stephen Chen, Karl Olaf Knutson, Jessy Thomas, David Michael Corns, II, Andrew Chu, Eric Andrew Faurie, Theodore Mazurkiewicz, Gary W. Grube
  • Publication number: 20190318674
    Abstract: A system of producing visual effects. The system includes an enclosure and a digital video display. The enclosure includes a plurality of sidewalls each having a reflective inner surface facing one other. At least one of the plurality of sidewalls is a first semi-reflective sidewall. The digital video display is positioned to direct digital video imagery through the semi-reflective sidewall and into the enclosure. Light of the digital video imagery reflects off the reflective inner surfaces of plurality of sidewalls.
    Type: Application
    Filed: March 25, 2019
    Publication date: October 17, 2019
    Inventor: David Ralph Cicirelli
  • Publication number: 20190294666
    Abstract: A method includes generating a plurality of entigen groups from a set of phrases of a statement and identifying two plausible entigen groups based on a true meaning interpretation of the statement. The method further includes identifying a related entigen group based on a phrase of the statement and interpreting each of the two plausible entigen groups in light of the related entigen group to determine whether one of the two plausible entigen groups is a more likely interpretation of the statement than the other one of the two plausible entigen groups. When the one of the two plausible entigen groups is the more likely interpretation of the statement, the method further includes updating the one of the two plausible entigen groups using the related entigen group to produce an updated entigen group and adding the statement as the updated entigen group to a knowledge database.
    Type: Application
    Filed: March 21, 2019
    Publication date: September 26, 2019
    Applicant: entigenlogic LLC
    Inventors: Frank John Williams, David Ralph Lazzara, Donald Joseph Wurzel, Stephen Chen, Dennis Arlen Roberson, Andrew Chu, Gary W. Grube
  • Patent number: 10408836
    Abstract: Provided herein is a method of detecting the presence of influenza virus in a sample while minimizing false positives due to presence of one or more other pathogens in the sample, the method including measuring the enzymatic activity of neuraminidase (NA) in the sample under one or more differentiating conditions selected from the group consisting of pH, binding to anti-NanA antibody, size exclusion, hemagglutinin (HA) binding, chemical inhibition, and combinations thereof.
    Type: Grant
    Filed: October 5, 2016
    Date of Patent: September 10, 2019
    Assignees: University of Cincinnati, MicrobeCapture, LLC
    Inventors: Alison A. Weiss, Karen Melissa Gallegos Villalobos, David Ralph
  • Publication number: 20190258717
    Abstract: A method includes interpreting sets of first language identigens to produce an entigen group which represents a most likely meaning of a string of first language words. The method further includes identifying, for each entigen of the entigen group, a corresponding set of second language identigens to identify sets of second language identigens. The method further includes selecting, for each entigen of the entigen group, a selected second language identigen from the corresponding set of second language identigens based on meaning of the entigen to produce an initial string of second language words.
    Type: Application
    Filed: January 25, 2019
    Publication date: August 22, 2019
    Applicant: entigenlogic LLC
    Inventors: Frank John Williams, David Ralph Lazzara, Stephen Chen, Karl Olaf Knutson, Jessy Thomas, David Michael Corns, II, Andrew Chu, Gary W. Grube
  • Publication number: 20190258655
    Abstract: A method includes generating a plurality of entigen groups from a plurality of phrases, where the plurality of entigen groups represents a plurality of most likely meanings for the plurality of phrases. The method further includes determining an initial interpretation of the related topic based on the plurality of most likely meanings for the plurality of phrases and generating a plurality of scores for the plurality of entigen groups based on the initial interpretation and source information of the plurality of phrases. The method further includes interpreting the plurality of scores in relation to the initial interpretation to determine a confidence level of the initial interpretation and when the confidence level of the initial interpretation compares favorably to a confidence threshold, indicating that the initial interpretation is reliable.
    Type: Application
    Filed: January 25, 2019
    Publication date: August 22, 2019
    Applicant: entigenlogic LLC
    Inventors: Frank John Williams, David Ralph Lazzara, Stephen Chen, Karl Olaf Knutson, Jessy Thomas, David Michael Corns, II, Andrew Chu, Gary W. Grube
  • Publication number: 20190220756
    Abstract: A method includes selecting an entigen group from a knowledge database. The entigen group is a most likely meaning of a phrase of a string of words. An entigen of the entigen group corresponds to a selected identigen from a set of identigens regarding a word of the string of words. The set of identigens represent different meanings of the word. The method further includes identifying other entigen groups of alternate phrases having the most likely meaning from the knowledge database. The alternate phrases are different permutations of the string of words. The method further includes determining a dominant digital representation of a human reaction of the other entigen groups and generating a digital representation of a human reaction for the entigen group based on the dominant digital representation of a human reaction.
    Type: Application
    Filed: December 24, 2018
    Publication date: July 18, 2019
    Applicant: entigenlogic LLC
    Inventors: Frank John Williams, David Ralph Lazzara, Stephen Chen, Karl Olaf Knutson, Jessy Thomas, David Michael Corns, II, Andrew Chu, Gary W. Grube, Stephen Emerson Sundberg