Abstract: An intravascular catheter for peri-vascular or peri-urethral tissue ablation includes multiple needles advanced through supported guide tubes which expand around a central axis to engage the interior surface of the wall of the renal artery or other vessel of a human body allowing the injection an ablative fluid for ablating tissue, or nerve fibers in the outer layer or deep to the outer layer of the vessel, or in prostatic tissue. A method can involve injection of the ablative fluid over an extended time period of at least 10 seconds or with two injections at two different penetration depths to reduce or eliminate patient pain during ablation.

Abstract: Techniques are described herein for collapsing clinical event data into meaningful states of patient care. In various embodiments, time-ordered streams of clinical data associated with a plurality of respective patients may be divided into one or more respective pluralities of temporal segments. Each stream of clinical data may indicate a clinical history of a particular patient of the plurality of patients. Each of the one or more pluralities of temporal segments may have a different duration. In some embodiments, embedding(s) of the one or more pluralities of temporal segments into reduced dimensionality space(s) may be generated. Process mining may be performed on the embedding(s). Based on the process mining, one or more temporal health trajectories shared among the plurality of patients may be identified.

Abstract: A method and apparatus for reconfiguring flight control of an aircraft during a failure while the aircraft is flying. The method and apparatus provide a control law that is software-implemented and configured to automatically send flight control data to a mixing/mapping matrix. The method and apparatus also provide a reconfiguration management tool configured to communicate with the mixing/mapping matrix in order to safely transfer authority from a failed actuator to a back-up actuator. The method and apparatus also provide a sensor management tool for providing input to the reconfiguration management tool in order to smooth any transient conditions that may occur during reconfiguration. The method and apparatus provide for a way of smoothing any possible transient situation that might otherwise occur by employment of a fader, the fader being used to gradually convert positioning of failed actuators and positioning of reconfigured actuators.

Abstract: A system for transmitting discrete data packets of sensor measured values of operating parameters. The system includes a transmitting device configured to transmit the measured values per a transmittal protocol. The system includes a receiving device that receives the measured values processes the received measured values in accordance with a receiving protocol. The transmittal protocol includes: determining a most recent measured value for the sensor; selecting previous measured values for the sensor; comparing the most recent measured value to the previous measured values to determine a difference therebetween; and conditionally transmitting the most recent measured value based on the difference. The receiving protocol includes: determining a most recent received measured value for each of the sensors; deriving an analytic time based the most recent received measured values; and deriving a time-aligned value for one of the operating parameters measured by the sensors at the analytic time.

Abstract: A method for generating device specific thumbnails may includes receiving one or more databases on a computing device from a mobile electronic device where the one or more databases include a key file and a data file. The data file may include picture data and the key file may include an index to the picture data. Also, the method may include generating a synchronization set on the computing device wherein the synchronization set includes one or more picture files to be stored on the mobile electronic device. The one or more databases may be transformed to one or more updated databases, wherein the transforming includes updating the key file to index pictures included in the synchronization set and updating the data file to include thumbnails of the pictures included in the synchronization set. The one or more updated databases may be transmitted to the mobile electronic device.

Abstract: A welding helmet system is provided. The welding helmet system includes a protective shell and a welding display system. The welding display system is configured to be removably coupled to the protective shell. The welding display system is configured to receive data from a sensor, and to display a welding metric derived from the sensor via the image generation system.

Abstract: Some examples comprise a memory device including a memory region accessible by a receiving processing unit and a plurality of sending processing units, the memory region including a set of memory buffers identified by a set of buffer identifiers; a first FIFO buffer for communicating a first buffer identifier from the receiving processing unit to any of the sending processing units, the first buffer identifier corresponding to a memory buffer available for use by the any one sending processing unit in sending data to the receiving processing unit; and a second FIFO buffer for communicating a second buffer identifier to the receiving processing unit from any of the sending processing units, the second buffer identifier corresponding to a memory buffer containing data being sent to the receiving unit.

Abstract: Provided herein are antibodies that immunospecifically bind to BCMA. Also described are related polynucleotides capable of encoding the provided BCMA-specific antibodies or antigen-binding fragments, cells expressing the provided antibodies or antigen-binding fragments, as well as associated vectors and detectably labeled antibodies or antigen-binding fragments. In addition, methods of using the provided antibodies are described. For example, the provided antibodies may be used to diagnose, treat, or monitor BCMA-expressing cancer progression, regression, or stability; to determine whether or not a patient should be treated for cancer; or to determine whether or not a subject is afflicted with BCMA-expressing cancer and thus may be amenable to treatment with a BCMA-specific anti-cancer therapeutic, such as the multispecific antibodies against BCMA and CD3 described herein.

Abstract: Disclosed herein are embodiments of rapidly solidified alloys that comprise aluminum, a rare earth element, one or more additional alloying elements, such as aluminum, and an optional additive component. The alloy embodiments exhibit a unique microstructure as compared to microstructures obtained from other alloys that are not rapidly cooled. The disclosed aluminum-rare earth element alloys also exhibit improved mechanical properties without the need for post-processing heat treatments and further do not exhibit substantial coarsening.

Abstract: The present invention encompasses compounds of the formula (I) wherein the groups R1, Cy and Y are defined herein, which are suitable for the treatment of diseases related to BTK, and processes for making these compounds, pharmaceutical preparations containing these compounds, and their methods of use.

Abstract: An open ear clamp having a clamping device like a so-called Oetiker ear. To make the installation of the clamp on a pipe easier, the clamp is pre-deformed, for example, in the course of production, to such an extent that the clamp surrounds the pipe for which the clamp is intended without play. Because of the elasticity produced in the clamp by this pre-deformation, the clamp still can be moved effortlessly to the installation location on the pipe and yet is retained there in the position of the clamp and in the desired orientation.

Abstract: A welding helmet system is provided. The welding helmet system includes a protective shell and a welding display system. The welding display system is configured to be removably coupled to the protective shell. The welding display system is configured to receive data from a sensor, and to display a welding metric derived from the sensor via the image generation system.

Abstract: Apparatus and methods for space management in file systems provide a mechanism to enhance user interaction with multimedia devices. In some aspects, updated metadata of media content stored in a server is retrieved. A representation of the media content stored in the storage device and the media content stored in the server is outputted to the display. Selection of an action associated with the media content stored in the server when the mobile device is not connected to the server is enabled. The action, once selected, remains pending until the mobile device is connected to the server. Execution of the pending action when the mobile device is connected to the server is enabled. The pending action includes one of deleting a media file from the server or downloading a media file from the server.

Abstract: The present invention encompasses compounds of the formula (I) wherein the groups R1, Cy and Y are defined herein, which are suitable for the treatment of diseases related to BTK, and processes for making these compounds, pharmaceutical preparations containing these compounds, and their methods of use.

Abstract: A control method for optimizing or enhancing an operation of a power plant that includes thermal generating units for generating electricity. The power plant may include multiple possible operating modes differentiated by characteristics of operating parameters. The method may include tuning a power plant model so to configure a tuned power plant model. The method may further include simulating proposed operating modes of the power plant with the tuned power plant model. The simulating may include a simulation procedure that includes: defining a second operating period; selecting the proposed operating modes from the possible operating modes; with the tuned power plant model, performing a simulation run for each of the proposed operating modes whereby the operation of the power plant during the second operating period is simulated; and obtaining simulation results from each of the simulation runs.

Abstract: A method and apparatus for reconfiguring flight control of an aircraft during a failure while the aircraft is flying. The method and apparatus provide a control law that is software-implemented and configured to automatically send flight control data to a mixing/mapping matrix. The method and apparatus also provide a reconfiguration management tool configured to communicate with the mixing/mapping matrix in order to safely transfer authority from a failed actuator to a back-up actuator. The method and apparatus also provide a sensor management tool for providing input to the reconfiguration management tool in order to smooth any transient conditions that may occur during reconfiguration. The method and apparatus provide for a way of smoothing any possible transient situation that might otherwise occur by employment of a fader, the fader being used to gradually convert positioning of failed actuators and positioning of reconfigured actuators.

Abstract: Some examples comprise a memory device including a memory region accessible by a receiving processing unit and a plurality of sending processing units, the memory region including a set of memory buffers identified by a set of buffer identifiers; a first FIFO buffer for communicating a first buffer identifier from the receiving processing unit to any of the sending processing units, the first buffer identifier corresponding to a memory buffer available for use by the any one sending processing unit in sending data to the receiving processing unit; and a second FIFO buffer for communicating a second buffer identifier to the receiving processing unit from any of the sending processing units, the second buffer identifier corresponding to a memory buffer containing data being sent to the receiving unit.