Abstract: Disclosed are a display apparatus, a drive chip, and an electronic device. When determining that a disconnected signal line (DL) exists, a drive chip sends a control signal to a signal line repair module, so that shift output ends (OUT) of a plurality of shift units sequentially output enable signals, and the shift unit corresponding to a connection switch electrically connected to the disconnected signal line (DL) continuously outputs enable signals, so that the connection switch electrically connected to the disconnected signal line (DL) is continuously turned on. The display apparatus may repair a disconnected signal line without being returned to a factory and a manual operation.

Abstract: This invention relates to a robust optimal design method for photovoltaic cells. Firstly, the deterministic optimal model is established, which is solved by Monte Carlo method to obtain the maximum output power value of optimization objective and its corresponding design variable value, and then the design variable value obtained from deterministic optimization is deemed as the initial point of the mean value of the robust optimal design variable. Later, the robust optimal model is solved by Monte Carlo method in order to obtain the mean value of design variable, and then appropriate materials and manufacturing techniques are selected for corresponding photovoltaic components according to the design variable obtained, so as to achieve the robust optimal design of photovoltaic cells. In fact, this invention improves the output stability and reliability of photovoltaic cells.

Abstract: A built-in micro interfacial enhanced reaction system and process for PTA production with PX are provided. The system includes a reactor and a micro interfacial unit disposed inside reactor. The reactor includes a shell, an inner cylinder concentrically disposed inside shell, and a circulating heat exchange device partially disposed outside shell, inner cylinder having a bottom end connected to inner bottom surface of the shell in closed manner and an open top end, a region between shell and inner cylinder being first reaction zone, inner cylinder containing second reaction zone and third reaction zone from top to bottom, circulating heat exchange device being connected to inner cylinder and micro interfacial unit respectively. The invention can solve problems of large waste of reaction solvent acetic acid under high temperature and high pressure and being unable to take out the product TA in time during existing process of PTA production with PX.

Abstract: The invention provides for systems, methods, and compositions for altering expression of target gene sequences and related gene products. Provided are structural information on the Cas protein of the CRISPR-Cas system, use of this information in generating modified components of the CRISPR complex, vectors and vector systems which encode one or more components or modified components of a CRISPR complex, as well as methods for the design and use of such vectors and components. Also provided are methods of directing CRISPR complex formation in eukaryotic cells and methods for utilizing the CRISPR-Cas system. In particular the present invention comprehends optimized functional CRISPR-Cas enzyme systems, wherein the guide sequence is modified by secondary structure to increase the specificity of the CRISPR-Cas system and whereby the secondary structure can protect against exonuclease activity and allow for 5? additions to the guide sequence.

Abstract: Materials and methods for creating canola (e.g., Brassica napus) lines having oil with increased oleic acid content are provided herein.

Abstract: Embodiments disclosed herein are directed to engineered CRISPR-Cas effector proteins that comprise at least one modification compared to an unmodified CRISPR-Cas effector protein that enhances binding of the of the CRISPR complex to the binding site and/or alters editing preference as compared to wild type. In certain example embodiments, the CRISPR-Cas effector protein is a Type V effector protein. In certain other example embodiments, the Type V effector protein is Cpf1. Embodiments disclosed herein are directed to viral vectors for delivery of CRISPR-Cas effector proteins, including Cpf1. In certain example embodiments, the vectors are designed so as to allow packaging of the CRISPR-Cas effector protein within a single vector. There is also an increased interest in the design of compact promoters for packing and thus expressing larger transgenes for targeted delivery and tissue-specificity.

Abstract: A computing-in-memory circuit includes a Resistive Random Access Memory (RRAM) array and a peripheral circuit. The RRAM array comprises a plurality of memory cells arranged in an array pattern, and each memory cell is configured to store a data of L bits, L being an integer not less than 2. The peripheral circuit is configured to, in a storage mode, write more than one convolution kernels into the RRAM array, and in a computation mode, input elements that need to be convolved in a pixel matrix into the RRAM array and read a current of each column of memory cells, wherein each column of memory cells stores one convolution kernel correspondingly, and one element of the convolution kernel is stored in one memory cell correspondingly, and one element of the pixel matrix is correspondingly input into a word line that a row of memory cells connect.

Abstract: The present invention provides a display panel and manufacturing method thereof, the method including following steps: providing a driving backplane and a light-emitting substrate, and bonding the driving backplane and the light-emitting substrate; patterning the light-emitting substrate to form a pixel array; forming a thin film packaging layer on an outside of the pixel array, the thin film packaging layer completely covering the pixel array; forming quantum dots on top of the thin film packaging layer to form a multi-color display; forming a reflective array between two adjacent quantum dots to avoid optical crosstalk between the pixel arrays. The display panel and the method of the present invention break through the physical limit of the high PPI, high-precision metal mask, which can realize the display of 2000 and higher PPI, and can prevent the optical crosstalk between the pixel arrays.

Abstract: The disclosure provides for systems, methods, and compositions for targeting and editing nucleic acids. In particular, the invention provides non-naturally occurring or engineered RNA-targeting systems comprising a RNA-targeting Cas13 protein, at least one guide molecule, and at least one adenosine deaminase protein or catalytic domain thereof.

Abstract: The embodiments disclosed herein utilized RNA targeting effectors to provide a robust CRISPR-based diagnostic with attomolar sensitivity. Embodiments disclosed herein can detect broth DNA and RNA with comparable levels of sensitivity and can differentiate targets from non-targets based on single base pair differences. Moreover, the embodiments disclosed herein can be prepared in freeze-dried format for convenient distribution and point-of-care (POC) applications. Such embodiments are useful in multiple scenarios in human health including, for example, viral detection, bacterial strain typing, sensitive genotyping, and detection of disease-associated cell free DNA.

Abstract: This application provides a BIER multicast traffic statistics collection method, a device, and a system. The method includes: A first network device obtains a first BIER packet. The first network device performs traffic statistics collection on the first BIER packet based on multicast flow information, to obtain a traffic statistics collection result of the first BIER packet, where the multicast flow information is used to identify a multicast flow to which the first BIER packet belongs. The first network device sends the multicast flow information and the traffic statistics collection result of the first BIER packet to a controller.

Abstract: Disclosed is a construction method for overhead jacking of a multi-track existing railway of a frame bridge. By means of construction modes of transition overhead construction-dewatering construction-formal overhead and two-end opposite jacking and middle cast-in-place, the risk caused by the groundwater level to a dig-hole pile is directly avoided. The overall construction scheme for the overpass pipe section follows the principle of segmented construction and line production, a jacking part of the overpass is firstly constructed, and after the jacking part is in place, a middle frame is cast in place, which guarantees not only the railway operation but also the construction period quality, and thus good economic benefits and construction guidance significance are achieved.

Abstract: Described herein are guided excision-transposition systems, methods of making, and uses thereof.

Abstract: The present disclosure provides for systems, methods, and compositions for targeting nucleic acids. In particular, the invention provides novel class 1, Type IV and novel class I, Type I Cas proteins and their use in modifying target sequences.

Abstract: A strengthening oxidation system of the external micro-interfacial unit for producing PTA with PX is provided, including: a reactor, a circulating heat exchange device and a micro-interfacial unit. The reactor includes an outer casing and an inner cylinder disposed concentrically inside the outer casing. The circulating heat exchange device is disposed at an exterior of the reactor, and is connected with the outer casing and the inner cylinder respectively, for regulating reaction temperatures of the first reaction zone, the second reaction zone and the third reaction zone inside the reactor in a reaction process of producing PTA with PX.

Abstract: The disclosure provides a connector and an electronic device using the connector. The connector is connected with a conductive element. The connector includes a terminal support component, a multiple of gold fingers and an electric conversion component. The terminal support component includes a first surface and a second surface. The first surface is opposite to the second surface or the first surface and the second surface are arranged at intervals. The multiple of gold fingers symmetrically arranged on the first surface and the second surface. The electric conversion component includes a main electric unit and two auxiliary conductive units. The main electric unit is electrically connected the two auxiliary conductive units and the conductive element. The two auxiliary conductive units are electrically connected with the gold fingers that respectively arranged on the first surface and the second surface of the terminal support component.

Abstract: The disclosure provides a connector and an electronic device using the connector. The connector subassembly includes two connectors that plug into each other, the connector includes a terminal support component, the terminal support component includes a first surface and a second surface, the first surface is opposite to the second surface or the first surface and the second surface are arranged at intervals; a multiple of gold fingers are symmetrically arranged on the first surface and the second surface; an electric conversion component includes a main electric unit and two auxiliary conductive units, the main electric unit is electrically connected the two auxiliary conductive units and a conductive element; the two auxiliary conductive units are electrically connected with the gold fingers. The gold fingers are respectively arranged on the first surface and the second surface of the terminal support component.

Abstract: The invention provides for systems, methods, and compositions for targeting nucleic acids. In particular, the invention provides non-naturally occurring or engineered DNA-targeting systems comprising a novel DNA-targeting CRISPR effector protein and at least one targeting nucleic acid component like a guide RNA. Methods for making and using and uses of such systems, methods, and compositions and products from such methods and uses are also disclosed and claimed.