Patents by Inventor Feng Zhang

Feng Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220417250
    Abstract: Authentication management by receiving a request to initiate an authentication from a computing device of a user, directing the request to a selected authentication service of a plurality of authentication services, wherein the selected authentication service is determined dynamically based on respective authentication metrics of the plurality of authentication services, receiving authentication information via the selected authentication service, and authenticating the user based on the received authentication information.
    Type: Application
    Filed: June 29, 2021
    Publication date: December 29, 2022
    Inventors: Feng Zhang, Peng Hui Jiang, TING YIN, Jun Su, Zhe Hua Peng
  • Publication number: 20220403357
    Abstract: The present disclosure provides for systems, methods, and compositions for targeting nucleic acids. In particular, the invention provides small Cas proteins and their use in modifying target sequences. In one aspect, the present disclosure provides a non-naturally occurring or engineered system comprising: a Cas protein that comprises a RuvC domain and a HNH domain, and is less than 850 amino acids in size; and a guide sequence capable of forming a complex with the Cas protein and directing the complex to bind to a target sequence.
    Type: Application
    Filed: November 12, 2020
    Publication date: December 22, 2022
    Applicants: THE BROAD INSTITUTE, INC., MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Feng Zhang, Soumya Kannan, Han Altae-Tran
  • Publication number: 20220402787
    Abstract: A treatment system and method for cephalosporin wastewater are disclosed. The treatment system includes: a flocculation and sedimentation device, an alkali reaction tank, a PAC reaction tank, a PAM reaction tank, a wastewater heat exchanger, a wastewater heater and an oxidation reactor that are connected with each other in sequence, wherein the wastewater heat exchanger is provided with a material inlet, a material outlet, a heat source inlet and a heat source outlet. An oxidized water from the oxidation reactor enters the wastewater heat exchanger from the heat source inlet, the heat source outlet is connected with a product canister, the product canister is connected with a membrane filtration device to realize concentration treatment of a landfill leachate, the material inlet is connected with the PAM reaction tank, and the material outlet is connected with the wastewater heater.
    Type: Application
    Filed: May 27, 2020
    Publication date: December 22, 2022
    Applicant: NANJING YANCHANG REACTION TECHNOLOGY RESEARCH INSTITUTE CO., LTD.
    Inventors: Zhibing ZHANG, Zheng ZHOU, Feng ZHANG, Lei LI, Weimin MENG, Baorong WANG, Gaodong YANG, Huaxun LUO, Guoqiang YANG, Hongzhou TIAN, Yu CAO
  • Patent number: 11531087
    Abstract: Methods, apparatus and systems for periodic or transient motion detection, e.g. fall event detection, based on wireless signals are described. In one example, a described system comprises: a transmitter configured for transmitting a first wireless signal through a wireless multipath channel of a venue; a receiver configured for receiving a second wireless signal through the wireless multipath channel; and a processor. The second wireless signal differs from the first wireless signal due to the wireless multipath channel that is impacted by a target motion of an object in the venue. The processor is configured for: obtaining a time series of channel information (TSCI) of the wireless multipath channel based on the second wireless signal, computing a time series of spatial-temporal information (STI) of the object based on the TSCI, and detecting the target motion of the object based on the time series of STI (TSSTI).
    Type: Grant
    Filed: February 20, 2021
    Date of Patent: December 20, 2022
    Assignee: ORIGIN WIRELESS, INC.
    Inventors: Yuqian Hu, Feng Zhang, Beibei Wang, Chenshu Wu, K. J. Ray Liu, Oscar Chi-Lim Au
  • Publication number: 20220396816
    Abstract: The present invention discloses a transaminase mutant and application thereof in preparation of sitagliptin intermediates, the transaminase mutant is obtained by substitution of tyrosine with proline at position 74, substitution of glutamic acid with aspartic acid at position 228, substitution of leucine with alanine at position 254 and substitution of methionine with threonine at position 290 of the amino acid sequence shown in SEQ ID NO: 2. The present invention uses wet cells or a purified transaminase as a biocatalyst and a sitagliptin precursor ketone or a prochiral carbonyl compound as a substrate to prepare a sitagliptin intermediate or a sitagliptin ester intermediate; the total yield of the method reaches about 82%, and e.e. value of the product reaches 99%.
    Type: Application
    Filed: January 21, 2021
    Publication date: December 15, 2022
    Inventors: Zhiqiang LIU, Feng CHENG, Xiaojian ZHANG, Dongxu JIA, Yuguo ZHENG, Renbao HE, Yizhong JIN, Hongming SHAO, Jiaohua LIN, Feng ZHANG
  • Publication number: 20220395803
    Abstract: A strengthening oxidation system of the external micro-interfacial unit for producing PTA with PX is provided, including: a reactor, a circulating heat exchange device and a micro-interfacial unit. The reactor includes an outer casing and an inner cylinder disposed concentrically inside the outer casing. The circulating heat exchange device is disposed at an exterior of the reactor, and is connected with the outer casing and the inner cylinder respectively, for regulating reaction temperatures of the first reaction zone, the second reaction zone and the third reaction zone inside the reactor in a reaction process of producing PTA with PX.
    Type: Application
    Filed: May 28, 2020
    Publication date: December 15, 2022
    Applicant: NANJING YANCHANG REACTION TECHNOLOGY RESEARCH INSTITUTE CO., LTD.
    Inventors: Zhibing ZHANG, Zheng ZHOU, Feng ZHANG, Lei LI, Weimin MENG, Baorong WANG, Gaodong YANG, Huaxun LUO, Guoqiang YANG, Hongzhou TIAN, Yu CAO
  • Publication number: 20220389451
    Abstract: Provided herein are compositions, systems, and methods for delivering cargo to a target cell. The compositions, systems, and methods comprise one or more polynucleotides encoding one or more endogenous retroviral elements for forming a delivery vesicle and one or more capture moieties for packaging a cargo within the delivery vesicle. The one or more endogenous retroviral elements for forming a delivery vesicle may comprise two or more of a retroviral gag protein, a retroviral envelope protein, a retroviral reverse transcriptase or a combination thereof. The retroviral gag protein alone, the retroviral envelope protein alone, or both the retroviral gag protein and retroviral envelope protein may be endogenous.
    Type: Application
    Filed: September 18, 2020
    Publication date: December 8, 2022
    Applicants: THE BROAD INSTITUTE, INC., MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Feng Zhang, Michael Segel
  • Publication number: 20220389460
    Abstract: Disclosed herein are methods and compositions useful in targeting a payload to, or editing a target nucleic acid, where a governing gRNA molecule is used to target, optionally inactivate, a Cas9 molecule or a Cas9 molecule/gRNA complex.
    Type: Application
    Filed: June 14, 2022
    Publication date: December 8, 2022
    Applicants: EDITAS MEDICINE, INC., THE BROAD INSTITUTE INC., THE UNIVERSITY OF IOWA RESEARCH FOUNDATION, MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Feng ZHANG, Deborah PALESTRANT, Beverly DAVIDSON, Jordi MATA-FINK, Edgardo RODRIGUEZ, Alexis BORISY
  • Publication number: 20220392987
    Abstract: A display substrate, a preparation method therefor, and a display apparatus. The display substrate includes a first metal layer, a metal oxide layer and a second metal layer, which are stacked on a base. The metal oxide layer includes a first active layer, the first active layer including a channel region, a source transition region, and a drain transition region, wherein both the source transition region and the drain transition region comprise a first region and a second region.
    Type: Application
    Filed: July 20, 2021
    Publication date: December 8, 2022
    Inventors: Ning LIU, Dacheng ZHANG, Jun GENG, Feng ZHANG, Yang PAN, Bin ZHOU, Liangchen YAN
  • Publication number: 20220389062
    Abstract: Provided herein are non-naturally occurring self-assembling polypeptides for transferring nucleic acids and/or proteins to a cell, pharmaceutical compositions comprising such polypeptides, and methods for treatment comprising use of such compositions. The methods for producing polypeptide compositions may include combining in a solution, unassembled recombinant GAG-like proteins, nucleic acids and/or proteins in low salt conditions; and increasing the ionic strength of the solution.
    Type: Application
    Filed: February 25, 2022
    Publication date: December 8, 2022
    Applicants: THE BROAD INSTITUTE, INC., MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Feng Zhang, Serge Gueroussov
  • Patent number: 11517868
    Abstract: A submerged propylene hydration micro-interface strengthening reaction system and a method are proposed. The system includes a reactor, a first micro-interface generator and a second micro-interface generator. Through the micro-interface generators, the propylene is broken to form micron-scale bubbles, which are mixed with reactants and deionized water to form a gas-liquid emulsion, so as to increase a phase boundary area between gas and liquid phases, and achieve a strengthening mass transfer effect under a lower preset operating condition. The micro-scale bubbles can be fully mixed with the deionized water to from a gas-liquid emulsion. By fully mixing gas and liquid phases, it can ensure that the deionized water in the system is in full contact with propylene, and they are fully in contact with the catalyst, which effectively improves the efficiency of preparing isopropanol.
    Type: Grant
    Filed: May 28, 2020
    Date of Patent: December 6, 2022
    Assignee: NANJING YANCHANG REACTION TECHNOLOGY RESEARCH INSTITUTE CO., LTD.
    Inventors: Zhibing Zhang, Zheng Zhou, Feng Zhang, Lei Li, Weimin Meng, Baorong Wang, Gaodong Yang, Huaxun Luo, Guoqiang Yang, Hongzhou Tian, Yu Cao
  • Publication number: 20220380758
    Abstract: Systems and methods for targeted gene modification, targeted insertion, perturbation of gene transcripts, and nucleic acid editing. Novel nucleic acid targeting systems comprise components of CRISPR systems and transposable elements.
    Type: Application
    Filed: October 30, 2020
    Publication date: December 1, 2022
    Applicants: THE BROAD INSTITUTE, INC., MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Makoto Saito, Feng Zhang, Guilhem Faure
  • Publication number: 20220373840
    Abstract: The present disclosure relates to a backlight module, a method for designing the same, and a display device. The backlight module includes: a first substrate; a plurality of LED chips on the first substrate; and a light control structure on the first substrate. The backlight module includes a plurality of light control region groups in one-to-one correspondence with the plurality of light-emitting diode chips, each light control region group includes at least a first light control region and a second light control region. The light control structure includes a plurality of light control substructure groups respectively located in the plurality of light control region groups. Each light control substructure group includes at least a first light control substructure in the first light control region and a second light control substructure in the second light control region.
    Type: Application
    Filed: June 8, 2021
    Publication date: November 24, 2022
    Applicant: BOE Technology Group Co., Ltd.
    Inventors: Xiaoxin Song, Feng Zhang, Wenqu Liu, Zhijun Lv, Liwen Dong, Zhao Cui, Detian Meng, Libo Wang, Dongfei Hou, Qi Yao, Xue Dong
  • Publication number: 20220372525
    Abstract: The invention provides for systems, methods, and compositions for targeting nucleic acids. In particular, the invention provides non-naturally occurring or engineered RNA-targeting systems comprising a novel RNA-targeting CRISPR effector protein and at least one targeting nucleic acid component like a guide RNA.
    Type: Application
    Filed: June 24, 2022
    Publication date: November 24, 2022
    Inventors: Konstantin Severinov, Feng Zhang, Yuri I. Wolf, Sergey Shmakov, Ekaterina Semenova, Leonid Minakhin, Kira S. Makarova, Eugene Koonin, Silvana Konermann, Julia Joung, Jonathan S. Gootenberg, Omar O. Abudayyeh, Eric S. Lander
  • Patent number: 11507596
    Abstract: An example method of live migration of distributed databases may include implementing a first database access mode with respect to a distributed database to be migrated from an original set of storage servers to a destination set of storage servers, wherein, in the first database access mode, database read requests are routed to the original set of storage servers and database update requests are routed to both the original set of storage servers and the destination set of storage servers. The method may further include copying a plurality of records of the distributed database from the original set of storage servers to the destination set of storage servers. The method may further include switching to a second database access mode, in which database read requests are routed to the destination set of storage servers and database update requests are routed to both the original set of storage servers and the destination set of storage servers.
    Type: Grant
    Filed: March 13, 2020
    Date of Patent: November 22, 2022
    Assignee: Electronic Arts Inc.
    Inventors: Greg William Schaefer, Anand Nair, Shengyong Li, MengXin Ye, Xin Feng Zhang, Miao Xiong, Jian Zhou
  • Publication number: 20220369009
    Abstract: An acoustic device comprises a shell and a sound producing assembly, the shell being provided with an installation hole and a sound outlet, and the sound producing assembly being fixed inside the shell. The sound producing assembly has a diaphragm separating a cavity of the acoustic device into a front cavity and a back cavity, a first part of the shell corresponding to the front cavity and/or a second part of the shell corresponding to the back cavity is provided with sapphire glass covering the installation hole, and the front cavity is in communication with the outside of the acoustic device through the sound outlet.
    Type: Application
    Filed: December 30, 2019
    Publication date: November 17, 2022
    Applicant: Goertek Inc.
    Inventors: CUILI ZHANG, Feng Zhang, Guoqiang Chen, He Liang, Jianxin Wang
  • Publication number: 20220364071
    Abstract: The present disclosure provides for systems, methods, and compositions for targeting nucleic acids. In particular, the invention provides mutated Cas13 proteins and their use in modifying target sequences as well as mutated Cas13 nucleic acid sequences and vectors encoding mutated Cas13 proteins and vector systems or CRISPR-Cas13 systems.
    Type: Application
    Filed: July 31, 2019
    Publication date: November 17, 2022
    Applicants: THE BROAD INSTITUTE, INC., MASSACHUSETTS INSTITUTE OF TECHNOLOGY, PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: Feng Zhang, Ian Slaymaker, Soumya Kannan, Jonathan Gootenberg, Omar Abudayyeh
  • Publication number: 20220368068
    Abstract: Disclosed is a fast self-adaptive rotary plug-in underwater force-bearing connector, which comprises a plug part and a socket part, wherein the plug part comprises a plug housing, a pin arranged in the plug housing, and a push-pull sleeve, a rotary sleeve, a front retaining ring, a ratchet lock nut and a rear retaining ring arranged outside the plug housing; the socket part comprises a socket housing and a jack arranged in the socket housing; the pin and the jack cooperate to connect the plug part and the socket part. The fast self-adaptive rotary plug-in underwater force-bearing connector of the present application can work under the working condition of a large tensile force and has a high reliability.
    Type: Application
    Filed: April 12, 2022
    Publication date: November 17, 2022
    Inventors: Feng ZHANG, Kaichen SONG, Yong WU, Yang NING
  • Publication number: 20220363603
    Abstract: A cerium-zirconium-aluminum-based composite material, a cGPF catalyst and a preparation method thereof are provided. The cerium-zirconium-aluminum-based composite material adopts a stepwise precipitation method, firstly preparing an aluminum-based pre-treated material, then coprecipitating the aluminum-based pre-treated material with zirconium and cerium sol, and finally roasting at high temperature to obtain the cerium-zirconium-aluminum-based composite material. The cerium-zirconium-aluminum-based composite material has better compactness and higher density, and when it is used in cGPF catalyst, it occupies a smaller volume of pores on the catalyst carrier, such that cGPF catalyst has lower back pressure and better ash accumulation resistance, which is beneficial to large-scale application of cGPF catalyst.
    Type: Application
    Filed: June 17, 2020
    Publication date: November 17, 2022
    Inventors: Dacheng LI, Jinfeng WANG, Li LAN, Hui YE, Lan YANG, Feng ZHANG, Yi YANG, Yongxiang CHENG, Tiantian LUO, Yinhua DONG, Yun WANG, Yun LI, Qizhang CHEN
  • Patent number: 11500056
    Abstract: Methods, apparatus and systems for wireless tracking with graph-based particle filtering are described. A described wireless monitoring system comprises a transmitter transmitting a series of probe signals, a receiver, and a processor. The receiver is configured for: receiving the series of probe signals modulated by the wireless multipath channel and an object moving in a venue, and obtaining a time series of channel information (TSCI) of the wireless multipath channel from the series of probe signals. The processor is configured for: monitoring a motion of the object relative to a map based on the TSCI, determining an incremental distance travelled by the object in an incremental time period based on the TSCI, and computing a next location of the object at a next time in the map based on at least one of: a current location of the object at a current time, the incremental distance, and a direction of the motion during the incremental time period.
    Type: Grant
    Filed: May 10, 2020
    Date of Patent: November 15, 2022
    Assignee: ORIGIN WIRELESS, INC.
    Inventors: Chenshu Wu, Feng Zhang, Beibei Wang, K. J. Ray Liu, Oscar Chi-Lim Au