Patents by Inventor Gregory S. Hamilton

Gregory S. Hamilton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Carbamate and urea compositions and neurotrophic uses
    Patent number: 6242468
    Abstract: This invention relates to pharmaceutical compositions and methods for effecting a neuronal activity using low molecular weight, small molecule carbamates and ureas having an affinity for FKBP-type immunophilins.
    Type: Grant
    Filed: August 25, 1998
    Date of Patent: June 5, 2001
    Inventors: Jia-He Li, Joseph P. Steiner, Gregory S. Hamilton
  • Pyrrolidine carboxylate and pyrrolidine amide hair revitalizing agents
    Patent number: 6239164
    Abstract: This invention relates to methods of treating hair loss, through hair revitalization and germination, by administering non-immunosuppresive pyrrolidine carboxylate and pyrrolidine amide compounds.
    Type: Grant
    Filed: August 9, 1999
    Date of Patent: May 29, 2001
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Joseph P. Steiner, Gregory S. Hamilton
  • Heterocyclic esters and amides
    Patent number: 6218544
    Abstract: This invention relates to neurotrophic low molecular weight, small molecule heterocyclic esters and amides having an affinity for FKBP-type immunophilins, and their use as inhibitors of the enzyme activity associated with immunophilin proteins, particularly peptidyl-prolyl isomerase, or rotamase, enzyme activity.
    Type: Grant
    Filed: November 18, 1999
    Date of Patent: April 17, 2001
    Assignee: Gpi Nil Holdings, Inc.
    Inventors: Jia-He Li, Gregory S. Hamilton
  • Heterocyclic ketone and thioester compounds and uses
    Patent number: 6218424
    Abstract: This invention relates to neurotrophic, low molecular weight, small molecule heterocyclic ketone and thioester compounds, compositions containing the same, and the use of such compounds for treating neurological disorders, including physically damaged nerves and neurodegenerative diseases.
    Type: Grant
    Filed: November 22, 1999
    Date of Patent: April 17, 2001
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Gregory S. Hamilton, Jia-He Li
  • Pyrrolidine derivatives for vision and memory disorders
    Patent number: 6218423
    Abstract: This invention relates to pharmaceutical compositions and methods for treating a vision disorder, improving vision, treating memory impairment, or enhancing memory performance using pyrrolidine derivatives.
    Type: Grant
    Filed: August 14, 1998
    Date of Patent: April 17, 2001
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Douglas T. Ross, Hansjörg Sauer, Gregory S. Hamilton, Joseph P. Steiner
  • Heterocyclic esters and amides
    Patent number: 6200972
    Abstract: This invention relates to neurotrophic low molecular weight, small molecule heterocyclic esters and amides having an affinity for FKBP-type immunophilins, and their use as inhibitors of the enzyme activity associated with immunophilin proteins, particularly peptidyl-prolyl isomerase, or rotamase, enzyme activity.
    Type: Grant
    Filed: February 23, 1998
    Date of Patent: March 13, 2001
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Jia-He Li, Gregory S. Hamilton
  • Small molecule carbamate or urea hair growth compositions and uses
    Patent number: 6194440
    Abstract: This invention relates to pharmaceutical compositions and methods for treating alopecia and promoting hair growth using small molecule carbamates and ureas.
    Type: Grant
    Filed: June 3, 1998
    Date of Patent: February 27, 2001
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Joseph P. Steiner, Gregory S. Hamilton
  • Small molecule pipecolic acid derivative hair growth compositions and uses
    Patent number: 6191125
    Abstract: This invention relates to pharmaceutical compositions and methods for treating alopecia and promoting hair growth using pipecolic acid derivatives.
    Type: Grant
    Filed: June 3, 1998
    Date of Patent: February 20, 2001
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Joseph P. Steiner, Gregory S. Hamilton
  • Sulfone hair growth compositions and uses
    Patent number: 6187796
    Abstract: This invention relates to pharmaceutical compositions and methods for treating alopecia and promoting hair growth using small molecule sulfonamides.
    Type: Grant
    Filed: June 3, 1998
    Date of Patent: February 13, 2001
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Joseph P. Steiner, Gregory S. Hamilton
  • Pipecolic acid derivative hair growth compositions and uses
    Patent number: 6187784
    Abstract: This invention relates to pharmaceutical compositions and methods for treating alopecia and promoting hair growth using pipecolic acid derivatives.
    Type: Grant
    Filed: June 3, 1998
    Date of Patent: February 13, 2001
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Joseph P. Steiner, Gregory S. Hamilton
  • N-linked sulfone of heterocyclic thioester hair growth compositions and uses
    Patent number: 6187806
    Abstract: This invention relates to pharmaceutical compositions and methods for treating alopecia and promoting hair growth using N-linked sulfonamides of heterocyclic thioesters.
    Type: Grant
    Filed: July 23, 1999
    Date of Patent: February 13, 2001
    Assignee: GPI NIL Holdings
    Inventors: Joseph P. Steiner, Gregory S. Hamilton
  • N-linked ureas and carbamates of heterocyclic thioesters
    Patent number: 6184243
    Abstract: This invention relates to neurotrophic low molecular weight, small molecule N-linked ureas and carbamates of heterocyclic thioesters having an affinity for FKBP-type immunophilins, and their use as inhibitors of the enzyme activity associated with immunophilin proteins, particularly peptidyl-prolyl isomerase, or rotamase, enzyme activity.
    Type: Grant
    Filed: October 2, 1998
    Date of Patent: February 6, 2001
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Gregory S. Hamilton, Jia-He Li, Wei Huang
  • Pyrrolidine derivative hair growth compositions and uses
    Patent number: 6177455
    Abstract: This invention relates to pharmaceutical compositions and methods for treating alopecia and promoting hair growth using pyrrolidine derivatives.
    Type: Grant
    Filed: June 3, 1998
    Date of Patent: January 23, 2001
    Assignee: Gpi Nil Holdings, Inc.
    Inventors: Joseph P. Steiner, Gregory S. Hamilton
  • N-oxide of heterocyclic ester, amide, thioester, or ketone hair growth compositions and uses
    Patent number: 6172087
    Abstract: This invention relates to pharmaceutical compositions and methods for treating alopecia and promoting hair growth using N-oxides of heterocyclic esters, amides, thioesters, or ketones.
    Type: Grant
    Filed: June 3, 1998
    Date of Patent: January 9, 2001
    Assignee: GPI NIL Holding, Inc.
    Inventors: Joseph P. Steiner, Gregory S. Hamilton
  • Small molecule inhibitors of rotamase enzyme activity
    Patent number: 6140357
    Abstract: This invention relates to neurotrophic N-glyoxylprolyl ester compounds having an affinity for FKBP-type immunophilins, their preparation and use as inhibitors of the enzyme activity associated with immunophilin proteins, and particularly inhibitors of peptidyl-prolyl isomerase or rotamase enzyme activity.
    Type: Grant
    Filed: April 8, 1997
    Date of Patent: October 31, 2000
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Gregory S. Hamilton, Joseph P. Steiner
  • N-linked sulfonamides of heterocyclic thioesters
    Patent number: 6121273
    Abstract: This invention relates to neurotrophic low molecular weight, small molecule N-linked sulfonamides of heterocyclic thioesters having an affinity for FKBP-type immunophilins, and their use as inhibitors of the enzyme activity associated with immunophilin proteins, particularly peptidyl-prolyl isomerase, or rotamase, enzyme activity.
    Type: Grant
    Filed: December 22, 1997
    Date of Patent: September 19, 2000
    Assignee: GPI NIL Holdings, Inc
    Inventors: Gregory S. Hamilton, Jai-He Li, Wei Huang
  • N-oxides of heterocyclic esters, amides, thioesters, and ketones
    Patent number: 6054452
    Abstract: This invention relates to neurotrophic low molecular weight, small molecule N-oxides of heterocyclic esters, amides, thioesters, and ketones having an affinity for FKBP-type immunophilins, and their use as inhibitors of the enzyme activity associated with immunophilin proteins, particularly peptidyl-prolyl isomerase, or rotamase, enzyme activity.
    Type: Grant
    Filed: July 9, 1998
    Date of Patent: April 25, 2000
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Gregory S. Hamilton, Joseph P. Steiner, Eric S. Burak
  • Inhibitors of rotamase enzyme activity
    Patent number: 6022878
    Abstract: This invention relates to the method of using neurotrophic pipecolic acid derivative compounds having an affinity for FKBP-type immunophilins as inhibitors of the enzyme activity associated with immunophilin proteins, and particularly inhibitors of peptidyl-prolyl isomerase or rotamase enzyme activity to stimulate or promote neuronal growth or regeneration.
    Type: Grant
    Filed: July 10, 1998
    Date of Patent: February 8, 2000
    Assignees: GPI NIL Holdings, Inc., John Hopkins University School of Medicine
    Inventors: Joseph P. Steiner, Solomon Snyder, Gregory S. Hamilton, Ted Dawson
  • N-linked sulfonamide of heterocyclic thioester hair growth compounds and uses
    Patent number: 6004993
    Abstract: This invention relates to pharmaceutical compositions and methods for treating alopecia and promoting hair growth using N-linked sulfonamides of heterocyclic thioesters.
    Type: Grant
    Filed: June 3, 1998
    Date of Patent: December 21, 1999
    Assignee: GPI Nil Holdings, Inc.
    Inventors: Joseph P. Steiner, Gregory S. Hamilton
  • Heterocyclic thioesters and ketones
    Patent number: 5990131
    Abstract: This invention relates to neurotrophic low molecular weight, small molecule heterocyclic thioesters and ketones having an affinity for FKBP-type immunophilins, and their use as inhibitors of the enzyme activity associated with immunophilin proteins, particularly peptidyl-prolyl isomerase, or rotamase, enzyme activity.
    Type: Grant
    Filed: August 1, 1997
    Date of Patent: November 23, 1999
    Assignee: Gpi Nil Holdings Inc.
    Inventors: Gregory S. Hamilton, Jia-He Li