Patents by Inventor Gregory S. Hamilton

Gregory S. Hamilton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Heterocyclic thioesters or ketones for vision and memory disorders
    Patent number: 6384056
    Abstract: This invention relates to pharmaceutical compositions and methods for treating a vision disorder, improving vision, treating memory impairment, or enhancing memory performance using heterocyclic thioesters and ketones.
    Type: Grant
    Filed: August 14, 1998
    Date of Patent: May 7, 2002
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Douglas T. Ross, Hansjörg Sauer, Gregory S. Hamilton, Joseph P. Steiner
  • INHIBITORS OF ROTAMASE ENZYME ACTIVITY
    Publication number: 20020052372
    Abstract: This invention relates to the method of using neurotrophic pipecolic acid derivative compounds having an affinity for FKBP-type immunophilins as inhibitors of the enzyme activity associated with immunophilin proteins, and particularly inhibitors of peptidyl-prolyl isomerase or rotamase enzyme activity to stimulate or promote neuronal growth or regeneration.
    Type: Application
    Filed: November 5, 1999
    Publication date: May 2, 2002
    Inventors: JOSEPH P. STEINER, SOLOMON SNYDER, GREGORY S. HAMILTON, TED DAWSON
  • Rotamase enzyme activity inhibitors
    Publication number: 20020052410
    Abstract: This invention relates to methods of using neurotrophic compounds having an affinity for FKBP-type immunophilins to stimulate or promote neuronal growth or regeneration and to prevent neuronal degeneration.
    Type: Application
    Filed: March 14, 2001
    Publication date: May 2, 2002
    Inventors: Joseph P. Steiner, Gregory S. Hamilton
  • N-linked sulfonamides of N-heterocyclic carboxylic acids or carboxylic acid isosteres
    Publication number: 20020052514
    Abstract: This invention relates to novel N-linked sulfonamides of N-heterocyclic carboxylic acid and carboxylic acid isosteres, their preparation, and use for treating neurological disorders including physically damaged nerves and neurodegenerative diseases, and for treating alopecia and promoting hair growth.
    Type: Application
    Filed: February 26, 2001
    Publication date: May 2, 2002
    Inventors: Gregory S. Hamilton, Mark H. Norman, Yong-Qian Wu
  • N-LINKED SULFONAMIDES OF N-HETEROCYCLIC CARBOXYLIC ACIDS OR CARBOXYLIC ACID ISOSTERES
    Publication number: 20020052510
    Abstract: This invention relates to novel N-linked sulfonamides of N-heterocyclic carboxylic acid and carboxylic acid isosteres, their preparation, and use for treating neurological disorders including physically damaged nerves and neurodegenerative diseases, and for treating alopecia and promoting hair growth.
    Type: Application
    Filed: December 3, 1998
    Publication date: May 2, 2002
    Inventors: GREGORY S. HAMILTON, MARK H. NORMAN, YONG-QIAN WU
  • N-linked carbamates and ureas of heterocyclic thioesters
    Publication number: 20020049199
    Abstract: This invention relates to neurotrophic low molecular weight, small molecule N-linked ureas and carbamates of heterocyclic thioesters having an affinity for FKBP-type immunophilins, and their use as inhibitors of the enzyme activity associated with immunophilin proteins, particularly peptidyl-prolyl isomerase, or rotamase, enzyme activity.
    Type: Application
    Filed: June 21, 2001
    Publication date: April 25, 2002
    Inventors: Gregory S. Hamilton, Jia-He Li, Wei Huang
  • N-linked sulfonamides of heterocyclic thioesters
    Publication number: 20020049193
    Abstract: This invention relates to neurotrophic low molecular weight, small molecule N-linked sulfonamides of heterocyclic thioesters having an affinity for FKBP-type immunophilins, and their use as inhibitors of the enzyme activity associated with immunophilin proteins, particularly peptidyl-prolyl isomerase, or rotamase, enzyme activity.
    Type: Application
    Filed: August 10, 2001
    Publication date: April 25, 2002
    Applicant: GPI NIL HOLDINGS, INC.
    Inventors: Gregory S. Hamilton, Jai-He Li, Wei Huang
  • Pipecolic acid derivatives for vision and memory disorders
    Patent number: 6376517
    Abstract: This invention relates to pharmaceutical compositions and methods for treating a vision disorder, improving vision, treating memory impairment, or enhancing memory performance using pipecolic acid derivatives.
    Type: Grant
    Filed: August 14, 1998
    Date of Patent: April 23, 2002
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Douglas T. Ross, Hansjörg Sauer, Gregory S. Hamilton, Joseph P. Steiner
  • Multiple heteroatom containing heterocyclic ring compounds substituted with carboxylic acids and isosteres thereof
    Publication number: 20020045641
    Abstract: The present invention is directed to novel carboxylic acids and isosteres of heterocyclic ring compounds which have multiple heteroatoms within the heterocyclic ring, novel derivatives containing N-linked diketos, sulfonamides, ureas and carbamates attached thereto, their preparation and use for treating neurological disorders including physically damaged nerves and neurodegenerative diseases, as well as for treating alopecia and promoting hair growth.
    Type: Application
    Filed: February 6, 2001
    Publication date: April 18, 2002
    Inventors: Gregory S. Hamilton, Mark H. Norman, Yong-Qian Wu
  • N-linked urea or carbamate of heterocyclic thioester hair growth compositons and uses
    Publication number: 20020045647
    Abstract: This invention relates to pharmaceutical compositions and methods for treating alopecia and promoting hair growth using N-linked ureas or carbamates of heterocyclic thioesters.
    Type: Application
    Filed: June 14, 2001
    Publication date: April 18, 2002
    Applicant: GPI NIL Holdings, Inc.
    Inventors: Joseph P. Steiner, Gregory S. Hamilton
  • Ureas and carbamates of N-Heterocyclic carboxylic acids and carboxylic acid isosteres
    Publication number: 20020042442
    Abstract: This invention relates to novel ureas or carbamates of N-heterocyclic carboxylic acids and carboxylic acid isosteres, their preparation and use for treating neurological disorders including physically damaged nerves and neurodegenerative diseases, and for treating alopecia and promoting hair growth.
    Type: Application
    Filed: May 3, 2001
    Publication date: April 11, 2002
    Applicant: Guilford Pharmaceuticals
    Inventors: Gregory S. Hamilton, Mark H. Norman, Yong-Qian Wu
  • Rotamase enzyme activity inhibitors
    Publication number: 20020042377
    Abstract: This invention relates to methods of using neurotrophic compounds having an affinity for FKBP-type immunophilins to stimulate or promote neuronal growth or regeneration and to prevent neuronal degeneration.
    Type: Application
    Filed: June 5, 2001
    Publication date: April 11, 2002
    Inventors: Joseph P. Steiner, Gregory S. Hamilton
  • Small molecule carbamate or urea hair growth compositions and uses
    Publication number: 20020037924
    Abstract: This invention relates to pharmaceutical compositions and methods for treating alopecia and promoting hair growth using small molecule carbamates and ureas.
    Type: Application
    Filed: February 26, 2001
    Publication date: March 28, 2002
    Applicant: GPI NIL Holdings, Inc.
    Inventors: Joseph P. Steiner, Gregory S. Hamilton
  • Aza compounds, pharmaceutical compositions and methods of use
    Publication number: 20020028814
    Abstract: The present invention relates to N-substituted cyclic aza compounds, pharmaceutical compositions comprising such compounds, and methods of their use for effecting neuronal activities.
    Type: Application
    Filed: April 17, 2001
    Publication date: March 7, 2002
    Inventors: Yong-Qian Wu, Wei Huang, Gregory S. Hamilton
  • Heterocyclic thioester and ketone hair growth compositions and uses
    Publication number: 20020016341
    Abstract: This invention relates to pharmaceutical compositions and methods for treating alopecia and promoting hair growth using heterocyclic thioesters and ketones.
    Type: Application
    Filed: June 12, 2001
    Publication date: February 7, 2002
    Applicant: GPI NIL Holdings, Inc.
    Inventors: Joseph P. Steiner, Gregory S. Hamilton
  • ROTAMAS ENZYME ACTIVITY INHIBITORS
    Publication number: 20020013344
    Abstract: This invention relates to the method of using specially formulated neurotrophic pipecolic acid derivative compounds having an affinity for FKBP-type immunophilins as inhibitors of the enzyme activity associated with immunophilin proteins, and particularly inhibitors of peptidyl-prolyl isomerase or rotamase enzyme activity to stimulate or promote neuronal growth or regeneration.
    Type: Application
    Filed: October 31, 1995
    Publication date: January 31, 2002
    Inventors: JOSEPH P. STEINER, GREGORY S. HAMILTON
  • N-linked sulfone of heterocyclic thioester hair growth compositions and uses
    Publication number: 20020010205
    Abstract: This invention relates to pharmaceutical compositions and methods for treating alopecia and promoting hair growth using N-linked sulfonamides of heterocyclic thioesters.
    Type: Application
    Filed: February 13, 2001
    Publication date: January 24, 2002
    Applicant: GPI NIL HOLDINGS, INC.
    Inventors: Joseph P. Stainer, Gregory S. Hamilton
  • Ureas of N-heterocyclic carboxylic acids and carboxylic acid isosteres
    Publication number: 20020007075
    Abstract: This invention relates to novel ureas or carbamates of N-heterocyclic carboxylic acids and carboxylic acid isosteres, their preparation and use for treating neurological disorders including physically damaged nerves and neurodegenerative diseases, and for treating alopecia and promoting hair growth.
    Type: Application
    Filed: January 30, 2001
    Publication date: January 17, 2002
    Inventors: Gregory S. Hamilton, Mark H. Norman, Yong-Qian Wu
  • N-linked sulfonamides of N-heterocyclic carboxylic acids or isosteres for vision and memory disorders
    Patent number: 6339101
    Abstract: This invention relates to novel compositions and uses of a N-linked sulfonamide of an N-heterocylic carboxylic acid or isostere thereof for treating a vision disorder or improving vision or treating memory impairment or enhancing memory performance in an animal.
    Type: Grant
    Filed: August 14, 1998
    Date of Patent: January 15, 2002
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Douglas T. Ross, Hansjörg Sauer, Gregory S. Hamilton, Joseph P. Steiner
  • Carboxylic acids and isosteres of heterocyclic ring compounds having multiple heteroatoms for vision and memory disorders
    Patent number: 6337340
    Abstract: This invention relates to novel compositions and uses of carboxylic acid or isostere of a heterocyclic ring compound having two or more heteroatoms within the heterocyclic ring and wherein the heterocyclic ring has at least one substituent attached thereto, the substituent selected from the group consisting of a diketo, a sulfonamide, a urea, a carbamate, and substituted derivatives thereof for treating a vision disorder or improving vision or treating memory impairment or enhancing memory performance in an animal.
    Type: Grant
    Filed: August 14, 1998
    Date of Patent: January 8, 2002
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Douglas T. Ross, Hansjörg Sauer, Gregory S. Hamilton, Joseph P. Steiner