Abstract: A high zirconia electrically fused cast refractory of high electric resistance having long time durability, less suffering from cracking during production and upon temperature rising, excellent in productivity, less forming zircon crystals even upon heating the refractory in itself and when the refractory is in contact with molten glass, generating less cracks even when undergoing heat cycles during operation of a glass melting furnace is provided. A high zirconia electrically fused cast refractory has, as chemical components, 85 to 95% by weight of ZrO2, 0.1 to less than 0.8% by weight of Al2O3, 3.5 to 10.0% by weight of SiO2, less than 0.05% by weight of Na2O and K2O in total, 0.1 to 1.5% by weight of B2O3, 0.1% by weight or less of MgO, 0.01 to 0.2% by weight of CaO, in the case where any one of BaO and SrO is contained, from 0.05 to 3.0% by weight of BaO or 0.01 to 3.0% by weight of SrO, or in the case where both of them are contained, 0.01% by weight or more of SrO and from 0.01% to 3.

Abstract: The present invention provides a novel alkylating agent specifically binding to the genetic mutation site of a driver oncogene. There are provided are a complex formed by binding an alkylating agent to a pyrrole imidazole polyamide specifically binding to the genetic mutation site of a driver oncogene, a driver oncogene mutation-specific alkylating agent comprising the aforementioned complex, and a pharmaceutical composition comprising the aforementioned complex.

Abstract: [Problems] To provide a high zirconia fused cast refractory that suffers less cracks in production and on heating, has excellent productivity, is hard to form zircon crystals with the refractory solely and under conditions where the refractory is in contact with molten glass, is hard to suffer cracks on receiving heat cycles in operation of a glass melting furnace, and has durability for a prolonged period of time. [Solution to Problems] A high zirconia fused cast refractory containing, as chemical components, from 85 to 95% by weight of ZrO2, from 0.4 to 2.5% by weight of Al2O3, from 3.5 to 10% by weight of SiO2, from 0.05 to 1% by weight in total of Na2O and K2O, more than 0.04% by weight and 1% by weight or less of B2O3, 0.02% by weight or less of P2O5, 0.05% by weight or less of MgO, from 0.01 to 0.2% by weight of CaO, in the case where any one of SrO and BaO is contained, from 0.3 to 3% by weight of SrO or more than 0.

Abstract: [Problems] To provide a high zirconia fused cast refractory that suffers less cracks in production and on heating, has excellent productivity, is hard to form zircon crystals with the refractory solely and under conditions where the refractory is in contact with molten glass, is hard to suffer cracks on receiving heat cycles in operation of a glass melting furnace, and has durability for a prolonged period of time. [Solution to Problems] A high zirconia fused cast refractory containing, as chemical components, from 85 to 95% by weight of ZrO2, from 0.4 to 2.5% by weight of Al2O3, from 3.5 to 10% by weight of SiO2, from 0.05 to 1% by weight in total of Na2O and K2O, more than 0.04% by weight and 1% by weight or less of B2O3, 0.02% by weight or less of P2O5, 0.05% by weight or less of MgO, from 0.01 to 0.2% by weight of CaO, in the case where any one of SrO and BaO is contained, from 0.3 to 3% by weight of SrO or more than 0.

Abstract: An evaluation unit includes a front-rear acceleration sensor and an up-down acceleration sensor. The evaluation unit calculates a length of a track obtained by plotting detected front-rear and up-down accelerations on a three-dimensional space along a time axis within a period from gear shift start of an automatic transmission to gear shift end, calculate a track length per unit time by dividing the length of the track by a time interval from the gear shift start to the gear shift end, and evaluates that a gear shift shock is larger as the track length per unit time is longer.

Abstract: According to one embodiment, a first slider of a disk storage apparatus includes a first head and flies over a first recording surface of a first disk. A heater element in the first head projects the first head toward the first recording surface of the first disk depending on heater power. A controller of the apparatus reduces a value for the heater power from a first value to a second value before performing a seek operation of moving the first head such that the first head moves across a concentric circular area including a protrusion on the first recording surface. The controller measures a wait time needed for a flying height of the first head to increase to a first flying height in response to the reduction and starts the seek operation after the wait time elapses.

Abstract: A metal bonded grinding stone is manufactured by heating and pressurizing a material including abrasive grains, a cobalt, a tungsten disulfide and a copper tin alloy to obtain a sintered product, and rapid-cooling the sintered product.

Abstract: A high-frequency power amplifier that amplifies a high-frequency input signal and outputs a signal having one power selected from a plurality of powers includes a high output route that is a circuit, which amplifies the input signal and outputs a signal of a high power, and a medium output route that is a circuit, which amplifies the input signal and outputs a signal of a medium power. The high output route includes a high-output amplifier that amplifies the input signal, an output matching circuit that is connected to an output node of the high-output amplifier, and a switch element that is connected to an output node of the output matching circuit. The medium output route includes a medium-output amplifier that amplifies the input signal and a switch element that is connected between an output node of the medium-output amplifier and an output node of the output matching circuit.

Abstract: According to an embodiment, an processing device includes a first obtaining unit, a second obtaining unit, and a display controller. The first obtaining unit is configured to obtain location information which indicates a location of a user. The second obtaining unit is configured to obtain movement information which indicates a movement performed by the user. The display controller is configured to perform control to display a personification medium on a display unit on which service information indicating information to be offered to the user. The personification medium fixes vision in a direction corresponding to the location specified in the location information and performs a movement in synchronization with the movement specified in the movement information.

Abstract: An evaluation unit includes a front-rear acceleration sensor and an up-down acceleration sensor. The evaluation unit calculates a length of a track obtained by plotting detected front-rear and up-down accelerations on a three-dimensional space along a time axis within a period from gear shift start of an automatic transmission to gear shift end, calculate a track length per unit time by dividing the length of the track by a time interval from the gear shift start to the gear shift end, and evaluates that a gear shift shock is larger as the track length per unit time is longer.

Abstract: A high-frequency power amplifier that amplifies a high-frequency input signal and outputs a signal having one power selected from a plurality of powers includes a high output route that is a circuit, which amplifies the input signal and outputs a signal of a high power, and a medium output route that is a circuit, which amplifies the input signal and outputs a signal of a medium power. The high output route includes a high-output amplifier that amplifies the input signal, an output matching circuit that is connected to an output node of the high-output amplifier, and a switch element that is connected to an output node of the output matching circuit. The medium output route includes a medium-output amplifier that amplifies the input signal and a switch element that is connected between an output node of the medium-output amplifier and an output node of the output matching circuit.

Abstract: An object of the present invention is to provide a total reflection measuring apparatus which, while visually observing a specific minute area of a measurement object, is capable of efficiently obtaining optical data on the basis of the total reflection measurement. A microscopic total reflection measuring apparatus of the present invention comprises a Cassegrain mirror 12 having a Cassegrain primary mirror 16 and a Cassegrain secondary mirror 18, which condenses an incident light beam 30 on a measurement object 20 by making an incident light beam successively reflected by the secondary mirror 18 and the primary mirror 16, and which obtains a reflected light beam 32 from the measurement object 20 by making the reflected light beam 32 successively reflected by the primary mirror 16 and the secondary mirror 18. And, a total reflection prism 14 is arranged below the Cassegrain secondary mirror 18.

Abstract: A metal bonded grinding stone is manufactured by heating and pressurizing a material including abrasive grains, a cobalt, a tungsten disulfide and a copper tin alloy to obtain a sintered product, and rapid-cooling the sintered product.

Abstract: A voice recognition apparatus includes: a voice recognition module that performs a voice recognition for an audio signal during a voice period; a distance measurement module that measures a current distance between the user and an voice input module; a calculation module that calculates a recommended distance range, in which being estimated that an S/N ratio exceeds a first threshold, based on the voice characteristic; and a display module that displays the recommended distance range and the current distance.

Abstract: A bias circuit 12 includes: a transistor Q5 operable to supply, to an amplifier 11, a bias current in accordance with a base current supplied thereto; a transistor Q3 operable to pass a current in accordance with a reference voltage Vref; a transistor Q2 operable to correct, in accordance with the current passed by the transistor Q3, the base current to be supplied to the transistor Q5, so as to compensate a temperature characteristic represented by the transistor Q5; and a bias changing section (of a transistor Q4, and resistances R5, R6, and R7), connected to a base of the transistor Q5, operable to change, in accordance with a control voltage VSW, an amount of the base current to be supplied to the transistor Q5. The amplifier 11 amplifies, by using the bias current supplied by the bias circuit 12, a radio frequency signal having been inputted thereto.

Abstract: To provide a radio frequency power amplifier that realizes a favorable high-frequency characteristic without using an isolator and also achieves low power consumption. The radio frequency power amplifier includes: a power amplifier which amplifies a radio frequency signal; a voltage supplying unit which supplies a collector voltage to the power amplifier; a current supplying unit which supplies a bias current to the power amplifier; and a bias current detecting unit which detects the bias current. The voltage supplying unit has a control unit which sets the power supply voltage at: a first voltage when the detected bias current is lower than a bias-current reference value; and a second voltage lower than the first voltage when the detected bias current is higher than the bias-current reference value.

Abstract: The present invention provides a target gene-specific histone modification regulator, which comprises a conjugate between a histone modification regulator and a polyamide capable of recognizing a regulatory region in a target gene. This enables the provision of a target gene-specific histone modification regulator.

Abstract: A TGF-? gene expression inhibitor containing a pyrrole-immidazole polyamide comprising an N-methylpyrrole unit (hereinafter also referred to as Py), an N-methylimidazole unit (hereinafter also referred to as Im) and a ?-aminobutyric acid unit which can be folded into an U-shaped conformation at the above-described ?-aminobutyric acid unit site in a minor groove of a double-stranded region (hereinafter referred to as the target region) containing a part or the whole of the following base sequence (SEQ ID NO: 2) corresponding to ?450 to ?310 of human transforming growth factor ?1 (hereinafter also referred to as h TGF-?1) promoter and a strand complementary thereto and in which a Py/Im pair, an Im/Py pair and a PY/Py pair correspond respectively to a C-G base pair, a G-C base pair and an A-T base pair and a T-A base pair.

Abstract: An object of the present invention is to provide a total reflection measuring apparatus which, while visually observing a specific minute area of a measurement object, is capable of efficiently obtaining optical data on the basis of the total reflection measurement. A microscopic total reflection measuring apparatus of the present invention comprises a Cassegrain mirror 12 having a Cassegrain primary mirror 16 and a Cassegrain secondary mirror 18, which condenses an incident light beam 30 on a measurement object 20 by making an incident light beam successively reflected by the secondary mirror 18 and the primary mirror 16, and which obtains a reflected light beam 32 from the measurement object 20 by making the reflected light beam 32 successively reflected by the primary mirror 16 and the secondary mirror 18. And, a total reflection prism 14 is arranged below the Cassegrain secondary mirror 18.

Abstract: A TGF-? gene expression inhibitor containing a pyrrole-imidazole polyamide having N-methylimidazole unit (hereinafter also referred to as Py), N-methylimidazole unit (hereinafter also referred to as Im) and ?-aminobutyrate unit which can be holded into an U-shaped conformation at the ?-aminobutyrate unit in the minor groove in a double helix region (hereinafter referred to as the target region) containing a complementary chain corresponding to the sequence at the ?557 to ?536 in the base sequence of a human transforming growth factor ?1 (hereinafter also referred to as hTGF-?1) promoter, either as a whole or a part thereof: TAAAGGAGAGCAATTCT-TACAG (SEQ ID NO: 1) wherein a Py/Im pair corresponds to a C-G base pair, an Im/Py pair corresponds to a G-C base pair, and Py/Py pairs correspond respectively to an A-A base pair and a T-A base pair.