Abstract: There is provided a novel pyrrole-imidazole polyamide compound for alkylating the specific base sequence of DNA, the polyamide compound being capable of being synthesized through fewer reaction steps than known hybrid molecules and having a combination of a high reactivity in DNA alkylation and the ability to recognize a sequence. Furthermore, there is provided an alkylating agent and a molecule serving as a drug, the alkylating agent and the molecule containing the polyamide compound.

Abstract: A bias circuit 12 includes: a transistor Q5 operable to supply, to an amplifier 11, a bias current in accordance with a base current supplied thereto; a transistor Q3 operable to pass a current in accordance with a reference voltage Vref; a transistor Q2 operable to correct, in accordance with the current passed by the transistor Q3, the base current to be supplied to the transistor Q5, so as to compensate a temperature characteristic represented by the transistor Q5; and a bias changing section (of a transistor Q4, and resistances R5, R6, and R7), connected to a base of the transistor Q5, operable to change, in accordance with a control voltage VSW, an amount of the base current to be supplied to the transistor Q5. The amplifier 11 amplifies, by using the bias current supplied by the bias circuit 12, a radio frequency signal having been inputted thereto.

Abstract: A bias circuit 12 includes: a transistor Q5 operable to supply, to an amplifier 11, a bias current in accordance with a base current supplied thereto; a transistor Q3 operable to pass a current in accordance with a reference voltage Vref; a transistor Q2 operable to correct, in accordance with the current passed by the transistor Q3, the base current to be supplied to the transistor Q5, so as to compensate a temperature characteristic represented by the transistor Q5; and a bias changing section (of a transistor Q4, and resistances R5, R6, and R7), connected to a base of the transistor Q5, operable to change, in accordance with a control voltage VSW, an amount of the base current to be supplied to the transistor Q5. The amplifier 11 amplifies, by using the bias current supplied by the bias circuit 12, a radio frequency signal having been inputted thereto.

Abstract: According to one aspect of the invention, a speech recognizer includes: an audio data acquiring portion configured to acquire audio data via a microphone; a speech section detecting portion configured to detect a talking start time and a talking end time based on the audio data; a spoken word identifying portion configured to identify the audio in a speech section from the talking start time to the talking end time; and a noise suppressing portion configured to suppress a generation of a noise from an electrical noise source for the speech section.

Abstract: A voice recognition apparatus includes: a voice recognition module that performs a voice recognition for an audio signal during a voice period; a distance measurement module that measures a current distance between the user and an voice input module; a calculation module that calculates a recommended distance range, in which being estimated that an S/N ratio exceeds a first threshold, based on the voice characteristic; and a display module that displays the recommended distance range and the current distance.

Abstract: A synthesis method for pyrrole-imidazole polyamide is automated at a higher level and can produce a product with a high yield in a more stable manner. In a solid phase synthesis method, the automated synthesis of a polyimide can be promoted by using HCTU as a condensation-activator, the yield of a product can be increased by charging a monomer in a solid form, and a pyrrole-imidazole polyamide having any sequence can be synthesis by combining the synthesis method with a manual synthesis with an acid chloride.

Abstract: It is intended to provide a novel monomer unit by which Z type DNA can be more effectively stabilized, a reagent for integrating this monomer unit into an oligonucleotide, and a method of stabilizing Z type DNA by using the reagent. Namely, a guanosine derivative represented by the following general formula [1]: wherein R1 represents acyl; R2 represents lower alkyl; R3 represents tri-substituted silyloxy or tetrahedropyranyloxy; and R4 represents cyanoethyl or allyl; a reagent for stabilizing Z type DNA which contains the guanosine derivative; and a method of stabilizing Z type DNA by using the guanosine derivative. It is also intended to provide a method of transferring guanosine having lower alkyl at the 8-position into an oligonucleotide by using the guanosine derivative; and an oligonucleotide carrying guanosine having lower alkyl at the 8-position transferred thereinto.

Abstract: A control apparatus for controlling first devices existing in an arbitrary place includes a first memory to store a plurality of device lists corresponding to a plurality of places respectively and each including device information items which indicate devices existing in corresponding one of the places, and a second memory to store a plurality of control information lists corresponding to the places respectively and each including control information items which indicate control operations for the devices existing in corresponding one of the places, and acquires first device information items indicating the first devices, detects an existence place of the first devices by comparing the first device information items with the device lists, and controls the first devices, based on one of the control information lists which corresponds to the existence place of the first devices.

Abstract: A method and apparatus for constructing a 3-dimensional image of the internal organs invisible by the conventional method is provided.

Abstract: It is intended to provide a pyrrole-imidazole polyamide type functional molecule having enhanced abilities of alkylating DNA and recognizing a sequence, compared with the existing functional molecules of this type, for a specific base sequence occurring on DNA. A hairpin polyamide having an alkylation site via a vinyl linker at the end of a pyrrole-imidazole polyamide. Drugs for inhibiting the expression of a specific gene and anticancer agents containing the above hairpin polyamide.

Abstract: In a service provider system, a service provider provides service information dependent on location information of a mobile terminal to the mobile terminal in response to a service request with the location information sent by the mobile terminal. A communication control unit controls communication between the mobile terminal and the service provider. The communication control unit converts a user identifier of the mobile terminal in the service request to a temporary identifier for the communication.

Abstract: In a service provider system, a service provider provides service information dependent on location information of a mobile terminal to the mobile terminal in response to a service request with the location information sent by the mobile terminal. A communication control unit controls communication between the mobile terminal and the service provider. The communication control unit converts a user identifier of the mobile terminal in the service request to a temporary identifier for the communication.

Abstract: A bias voltage is applied via a first resistance to the base of a first transistor, and a radio frequency signal is input via a first capacitor to the base of the first transistor. The bias voltage is applied via a second resistance to the base of a second transistor. The bias voltage is applied via a third resistance to the base of a third transistor, and the radio frequency signal RF is input via a third capacitor to the base of the third transistor. A first band rejection filter is provided between the base of the first transistor and the base of the second transistor. A second band rejection filter is provided between the base of the second transistor and the base of the third transistor. The collectors of the first to third transistors are connected in common and the emitters thereof are all grounded.

Abstract: A method and apparatus for constructing a 3-dimensional image of the internal organs invisible by the conventional method is provided.

Abstract: A method for screening the effect of a segment A (chemical species A) on a substance (for example, a cell) containing DNA or RNA by using artificial chemical species. Namely, a method of detecting or identifying the function of a chemical species A on a substance containing DNA or RNA by using one or more chemical species represented by the following general formula (I) which are capable of recognizing a DNA base sequence; a kit therefor; and a plate to be used therein: B-L-A (I) wherein B represents a chemical structure containing an non-natural base capable of recognizing a DNA base sequence; A represents a chemical structure having an interaction with DNA; and L represents a linker whereby the chemical structures A and B can be linked together.

Abstract: A TGF-? gene expression inhibitor containing a pyrrole-imidazole polyamide having N-methylimidazole unit (hereinafter also referred to as Py), N-methylimidazole unit (hereinafter also referred to as Im) and ?-aminobutyrate unit which can be holded into an U-shaped conformation at the ?-aminobutyrate unit in the minor groove in a double helix region (hereinafter referred to as the target region) containing a complementary chain corresponding to the sequence at the -557 to -536 in the base sequence of a human transforming growth factor ?1 (hereinafter also referred to as hTGF-?1) promoter, either as a whole or a part thereof: TAAAGGAGAGCAATTCT-TACAG (SEQ ID NO: 1) wherein a Py/Im pair corresponds to a C-G base pair, an Im/Py pair corresponds to a G-C base pair, and Py/Py pairs correspond respectively to an A-A base pair and a T-A base pair.

Abstract: A bias circuit 12 includes: a transistor Q5 operable to supply, to an amplifier 11, a bias current in accordance with a base current supplied thereto; a transistor Q3 operable to pass a current in accordance with a reference voltage Vref; a transistor Q2 operable to correct, in accordance with the current passed by the transistor Q3, the base current to be supplied to the transistor Q5, so as to compensate a temperature characteristic represented by the transistor Q5; and a bias changing section (of a transistor Q4, and resistances R5, R6, and R7), connected to a base of the transistor Q5, operable to change, in accordance with a control voltage VSW, an amount of the base current to be supplied to the transistor Q5. The amplifier 11 amplifies, by using the bias current supplied by the bias circuit 12, a radio frequency signal having been inputted thereto.

Abstract: A bias current to be supplied to an amplification circuit 60 is drawn out of a collector of a transistor Q11 of a bias circuit 10. The drawn-out bias current is input to a base of a transistor Q13 via an attenuation filter F2 and is output from an emitter of the transistor Q13 in the state where the voltage thereof is reduced by a level corresponding to Vbe. The attenuation filter F2 is conducted in a DC manner, and attenuates a component of a frequency fH(=2ft?fr) defined by a transmission frequency ft and a receiving frequency fr of a radio frequency signal. The bias current output from the emitter of the transistor Q13 is supplied to the amplification circuit 60 via an attenuation filter F1. The attenuation filter F1 is conducted in a DC manner, and attenuates a component of a frequency fL(=|fr?ft|).

Abstract: There is provided a novel pyrrole-imidazole polyamide compound for alkylating the specific base sequence of DNA, the polyamide compound being capable of being synthesized through fewer reaction steps than known hybrid molecules and having a combination of a high reactivity in DNA alkylation and the ability to recognize a sequence. Furthermore, there is provided an alkylating agent and a molecule serving as a drug, the alkylating agent and the molecule containing the polyamide compound.

Abstract: A bias voltage is applied via a first resistance to the base of a first transistor, and a radio frequency signal is input via a first capacitor to the base of the first transistor. The bias voltage is applied via a second resistance to the base of a second transistor. The bias voltage is applied via a third resistance to the base of a third transistor, and the radio frequency signal RF is input via a third capacitor to the base of the third transistor. A first band rejection filter is provided between the base of the first transistor and the base of the second transistor. A second band rejection filter is provided between the base of the second transistor and the base of the third transistor. The collectors of the first to third transistors are connected in common and the emitters thereof are all grounded.