Abstract: The present invention relates to a single use, non-expandable, disposable container for holding a liquid, in particular a body liquid, the container comprising: —a bottom wall, —a circumferential side wall which extends in an upward direction from the bottom wall, wherein the circumferential side wall defines an upper opening ( ) at an upper end ( ) of the container, —a first folding flap and a second folding flap which are connected via a respective first folding line and a second folding line to opposed sections of an upper edge of the circumferential side wall, wherein the first and second folding flaps are foldable between an open position and a closed position, wherein in the open position of the folding flaps the circumferential side wall and the folding flaps taper outwardly in an upward direction, allowing the container to be nested, and wherein the folding flaps have a varying flap width, wherein the flap width reaches a maximum at a central portion of the folding flaps, and wherein said maximum flap

Abstract: Embodiments are directed towards generating and managing schedules. In at least one of the various embodiments, these schedules may be configured to schedule team members, rotating which team member is active (“on-call”). In at least one of the various embodiments, these may be employed to determine which resource is responsible to respond and/or resolve incidents that may be reported and/or detected. In at least one of the various embodiments, if a team member is determined to be the on-call or responsible team member, the notification engine may determine the methods for notify the responsible of the incidents. Schedules previews may be updated in real-time as the schedule is edited.

Abstract: This disclosure relates to the isolation and sequencing of nucleic acid molecules that encode cytochrome P450 polypeptides from a Papaver somniferum cultivar; uses in the production of noscapine and identification of poppy cultivars that include genes that comprise said nucleic acid molecules.

Abstract: Embodiments are directed towards generating and managing schedules. In at least one of the various embodiments, these schedules may be configured to schedule team members, rotating which team member is active (“on-call”). In at least one of the various embodiments, these may be employed to determine which resource is responsible to respond and/or resolve incidents that may be reported and/or detected. In at least one of the various embodiments, if a team member is determined to be the on-call or responsible team member, the notification engine may determine the methods for notify the responsible of the incidents. Schedules previews may be updated in real-time as the schedule is edited.

Abstract: Polypeptides are encoded by an adeno-associated virus (AAV)-derived endogenous viral element (mAAV-EVE1) found within the germline of numerous closely-related marsupial species. Nucleic acid molecules encode the polypeptides. Vectors can include the nucleic acid molecules, and recombinant AAV virions can include the polypeptides. A chimeric capsid protein can also include an MAAV-EVE1 polypeptide.

Abstract: A computing system includes a database server configured to receive data including a plurality of elements each including a sensor identifier and time element, each time element including a timestamp or time period, and create a time series of the data indexed by the sensor identifiers into buckets spaced at even time intervals. The database server is configured to receive a query including at least one of the sensor identifiers and at least one query time element. The database server is configured to locate target data in the buckets by the at least one of the sensor identifiers and the at least one query time element and output the target data.

Abstract: Apparatus (2) for use with a laryngeal mask airway device (4), wherein the apparatus is configured to collect regurgitated fluid from a patient during use of the laryngeal mask airway device, wherein the apparatus is adapted for attachment to a gastric port (8) provided on the laryngeal mask airway device.

Abstract: This disclosure relates to the isolation and sequencing of nucleic acid molecules that encode cytochrome P450 polypeptides from a Papaver somniferum cultivar; uses in the production of noscapine and identification of poppy cultivars that include genes that comprise said nucleic acid molecules.

Abstract: Methods and systems of managing settings are described. According to various embodiments, a settings page corresponding to a user's settings on an online service may be caused to be displayed on a device. The settings page may comprise selectable category setting options for a setting category. The setting category may have a plurality of subcategories, and each subcategory may have its own selectable subcategory setting options. Each one of the category setting options may correspond to its own distinct configuration of subcategory setting options for its subcategories. A user input indicating a selection of one of the category setting options for the setting category may be received. The configuration of subcategory setting options corresponding to the selected one of the category setting options for the setting category may be applied to the user's settings on the online service.

Abstract: A waste storage device includes a container in which a cassette is mounted. Tubing is pulled through the centre of the cassette to store packages separated by twists. The cassette is rotated relative to the container to provide the twists between packages by virtue of a rotatable disk and user grip portion. The package is gripped against rotation by a gripper diaphragm and is guided towards a wall of the container by a guide diaphragm to prevent untwisting between packages.

Abstract: Methods of treatment of complement-mediated disorders, in particular disorders associated with over-activity of the complement C3b feedback cycle (for example, age-related macular degeneration (AMD)), using gene therapy is described. According to the methods, levels of complement Factor I are elevated by administration of a recombinant viral vector encoding Factor I such that a therapeutically effective amount of the encoded Factor I is expressed from the vector in the subject. Recombinant viral vectors encoding Factor I, recombinant virus particles encapsidating the vectors, and their use in the methods of treatment, is also described.

Abstract: In combination a wear indicator and a component of a gas turbine engine is provided. The wear indicator is secured to a surface of the component of the gas turbine engine. The wear indicator comprising: a first side delaminates when impacted by a blade of the gas turbine engine; a second side parallel to the first side, the second side being secured to a surface of the component of the gas turbine engine; a mid-section interposed between the first side and the second side; and a reference dimension remains constant when the first side delaminates.

Abstract: Provided herein are methods for facilitating or inducing stable transgene integration and expression in a proliferating cell, comprising administering to the cell (i) a recombinant AAV (rAAV) vector comprising the transgene flanked by transposon-derived inverted terminal repeat sequences, which sequences are in turn flanked by AAV-derived inverted terminal repeat regions, and (ii) a source of a transposase that recognises said transposon-derived inverted terminal repeat sequences and directs the genomic integration of the transgene into the genome of the proliferating cell. Also provide are methods and transgene delivery systems for the treatment or prevention of diseases affecting, associated with or characterised by proliferating cells.

Abstract: Chemical compositions and techniques for treating wool (and other animal hair-based) fabrics, and in particular for unshrinking wool fabrics and garments.

Abstract: The present invention relates to a single-use container (200) manufactured from sheet material, the single-use container comprising: a base (206), wherein the base is flat and forms a surface on which the single-use container can stand,—a front wall (201), a right wall (202), a left wall (203) and a rear wall (204) which extend upward from the base, wherein the front wall and the rear wall are convex, and wherein the right wall and left wall are concave, an upper end (207) which connects the front wall, right wall, left wall and rear wall.

Abstract: This disclosure relates to the isolation and sequencing of nucleic acid molecules that encode cytochrome P450 polypeptides from a Papaver somniferum cultivar; uses in the production of noscapine and identification of poppy cultivars that include genes that comprise said nucleic acid molecules.

Abstract: Methods for removing biofilm or preventing biofilm formation from surfaces are provided, the methods comprising applying compositions to the surface to remove the biofilm or inhibit its formation, the compositions comprising polymers derived from alkyl polyglucosides functionalized with cationic side chains.

Abstract: This disclosure relates to the isolation and sequencing of nucleic acid molecules that encode cytochrome P450 polypeptides from a Papaver somniferum cultivar; uses in the production of noscapine and identification of poppy cultivars that include genes that comprise said nucleic acid molecules.

Abstract: Polypeptides are encoded by an adeno-associated virus (AAV)-derived endogenous viral element (mAAV-EVE1) found within the germline of numerous closely-related marsupial species. Nucleic acid molecules encode the polypeptides. Vectors can include the nucleic acid molecules, and recombinant AAV virions can include the polypeptides. A chimeric capsid protein can also include an MAAV-EVE1 polypeptide.