Abstract: Based on an analysis of example content items, a proposed initial version of an application to be generated on behalf of a client is determined. At least a portion of a software program implementing the application is generated, and an indication of the software program is provided to the client. Based on input received from the client, additional operations associated with the program are initiated.

Abstract: The present disclosure relates to amorphous and crystalline forms of (R)-N-(4-chlorophenyl)-2-(1S,4S)-4-(6-fluoroquinolin-4-yl)cyclohexyl)propanamide and its salts and hydrates, processes for their production, pharmaceutical compositions comprising them, and methods of treatment using them.

Abstract: The disclosure is directed to improved methods for preparing substituted quinolinylcyclohexylpropanamide compounds.

Abstract: The disclosure is directed to improved methods for preparing substituted quinolinylcyclohexylpropanamide compounds.

Abstract: The present disclosure relates to amorphous and crystalline forms of (R)-N-(4-chlorophenyl)-2-((1S,4S)-4-(6-fluoro-quinolin-4-yl) cyclohexyl)propanamide and its salts and hydrates, processes for their production, pharmaceutical compositions comprising them, and methods of treatment using them.

Abstract: Systems, methods and containers for forming a beverage. A container includes a closure arranged with a movable element that is movable to pierce a membrane and permit beverage material in the container to exit. The movable element can include a piercing element that pierces the membrane. Gas can be introduced into the container to force beverage material to exit the container. A gas inlet port can be provided with the closure and arranged to mate with a gas source of a beverage machine.

Abstract: Systems, methods and containers for forming a beverage. A container includes a closure arranged with a movable element that is movable to pierce a membrane and permit beverage material in the container to exit. The movable element can include a piercing element that pierces the membrane. Gas can be introduced into the container to force beverage material to exit the container. A gas inlet port can be provided with the closure and arranged to mate with a gas source of a beverage machine.

Abstract: Based on an analysis of example content items, a proposed initial version of an application to be generated on behalf of a client is determined. At least a portion of a software program implementing the application is generated, and an indication of the software program is provided to the client. Based on input received from the client, additional operations associated with the program are initiated.

Abstract: Based on an analysis of example content items, a proposed initial version of an application to be generated on behalf of a client is determined. At least a portion of a software program implementing the application is generated, and an indication of the software program is provided to the client. Based on input received from the client, additional operations associated with the program are initiated.

Abstract: At a data management service, a child template associated with a parent group of one or more cells of a first data sheet is stored. In response to detecting that a parent cell has been added to the parent group, a particular child data sheet is instantiated automatically in accordance with the template. In response to a change to a value in a first cell of the child data sheet, a corresponding value of a cell of the first data sheet is modified.

Abstract: The invention provides a textile panel including a knitted or woven textile layer (12) having yarn of a first type (14), and a coating applied to at least one face of the textile layer. The textile layer includes at least one textile sensor (18) formed by an electrically conductive region of the textile layer which includes yarn (16) of a second type incorporated in the knit or weave of the textile layer, the second type of yarn being electrically conductive. The invention also provides a method of manufacturing a textile panel, including knitting or weaving a textile layer (12) using a first type of yarn (14) and a second type of yarn (16), the second type of yarn being incorporated in the knit or weave of the textile layer in at least one predetermined region to form a textile sensor, the method further including applying a coating to the textile layer.

Abstract: Representations of a set of cards are displayed via an application authoring interface. A given card represents one or more screen layouts of an application, and contents of a particular card are based on contents of a data sheet materialized in accordance with a data model which enables automatic instantiation of child data sheets associated with a parent cell within a parent data sheet. In response to detecting an edit operation directed at a particular card, an updated representation of the particular card is displayed at the first application authoring interface, and a screen layout corresponding to the updated representation is rendered at a particular mobile computing device.

Abstract: At a data management service, a child template associated with a parent group of one or more cells of a first data sheet is stored. In response to detecting that a parent cell has been added to the parent group, a particular child data sheet is instantiated automatically in accordance with the template. In response to a change to a value in a first cell of the child data sheet, a corresponding value of a cell of the first data sheet is modified.

Abstract: Representations of a set of cards are displayed via an application authoring interface. A given card represents one or more screen layouts of an application, and contents of a particular card are based on contents of a data sheet materialized in accordance with a data model which enables automatic instantiation of child data sheets associated with a parent cell within a parent data sheet. In response to detecting an edit operation directed at a particular card, an updated representation of the particular card is displayed at the first application authoring interface, and a screen layout corresponding to the updated representation is rendered at a particular mobile computing device.

Abstract: A gaming machine includes at least one sound-generating display device. The sound-generating display device is configured to not only display information such as game information, but to generate sound. In one embodiment one or more transducers are mounted to a back or rear portion of a video display and cause one or more portions of the video display, such as a front panel thereof, to move, thus generating sound. The one or more transducers are controlled to generate sound, including to generate sound which has sound which is perceived to emanate from particular areas of the video display.

Abstract: Disclosed herein are novel formulations containing relacorilant ((R)-(1-(4-fluorophenyl)-6-((1-methyl-1H-pyrazol-4-yl)sulfonyl)-4,4a,5,6,7,8-hexahydro-1H-pyrazolo[3,4-g]isoquinolin-4a-yl)(4-(trifluoromethyl)pyridin-2-yl)methanone) that are suitable for administration, including oral administration, to patients suffering from disorders amenable to treatment by glucocorticoid receptor modulators (GRMs). Single unit dosage forms comprise softgel capsules containing these formulations. Such softgel capsules may contain, e.g., relacorilant formulations containing 25 milligrams (mg), 50 mg, 100 mg, 200 mg, 300 mg, 400 mg, 500 mg, or other amounts of relacorilant. These novel formulations and single unit dosage forms may be used to treat diseases and disorders including Cushing's syndrome, Cushing's Disease, and other disorders.

Abstract: A hinge has a door interface comprising a serrated surface and an oversized hole, a bolt at least partially extending into the oversized hole, and a washer disposed on the bolt and captured between the door interface and a head of the bolt, the washer comprising a serrated surface facing toward the serrated surface of the door interface. The oversized hole has a diameter selected to allow significant radial movement of the bolt within the oversized hole.

Abstract: Described herein is a beverage system that is configured to produce beverages having different characteristics, such as different levels of carbonation including producing substantially non-carbonated beverages and carbonated beverages with a single machine. The beverage system includes a beverage appliance and a beverage container. The beverage container includes a beverage material, which can include a flavoring ingredient for a target beverage. The beverage appliance is used to access the beverage material from the beverage container and produce the target beverage. The beverage appliance and beverage container are adaptable to produce the target beverage having any of a range of carbonation levels or other characteristics.

Abstract: The disclosure is directed to improved methods for preparing substituted quinolinylcyclohexylpropanamide compounds.