Abstract: A mixing chamber for use in a beverage carbonation system is provided. In one embodiment, the carbonation mixing chamber includes a housing, a fluid inlet pathway, a gas inlet pathway, and an outlet pathway. The housing may have an inner chamber, and the fluid inlet pathway can be configured to extend into the inner chamber of the housing and receive fluid from a fluid source. The gas inlet pathway can be configured to extend into the inner chamber of the housing and can be configured to receive gas from a gas source. The gas inlet pathway can include a plurality of nozzles positioned within the inner chamber and configured to direct gas in a plurality of directions that differ from one another. The outlet pathway can be configured to dispense a mixture of fluid and gas from the inner chamber.

Abstract: A system may include an electronic display panel having pixels, where each pixel may emit light based on a respective programming signal. The system may include a memory storing a map. The processing circuitry may determine a function for each pixel from the map. The processing circuitry may determine a respective control signal based on the function and a target brightness level for each pixel to generate multiple control signals, where the respective control signal is used to generate the respective programming signal for each pixel. The processing circuitry may determine a scaling factor based at least in part on the first map and may scale at least a subset of the multiple control signals based at least in part on the scaling factor.

Abstract: An integrated circuit includes: a gate dielectric; a first layer adjacent to the gate dielectric; a second layer adjacent to the first layer, the second layer comprising an amorphous material; a third layer adjacent to the second layer, the third layer comprising a crystalline material; and a source or drain at least partially adjacent to the third layer. In some cases, the crystalline material of the third layer is a first crystalline material, and the first layer comprises a second crystalline material, which may be the same as or different from the first crystalline material. In some cases, the gate dielectric includes a high-K dielectric material. In some cases, the gate dielectric, the first layer, the second layer, the third layer, and the source or drain are part of a back-gate transistor structure (e.g., back-gate TFT), which may be part of a memory structure (e.g., located within an interconnect structure).

Abstract: One aspect provides a modular inspection robot for inspecting vertical shafts, chambers or tunnels. An embodiment provides related methods and products. One method includes: capturing, using a plurality of video cameras associated with an infrastructure inspection unit, two or more videos of infrastructure; accessing, using one or more processors, image metadata indicating a mesh of connected vertices based on the two or more videos; selecting, using the one or more processors, image data of frames of the two or more videos for inclusion in an output based on the mesh; and outputting, using the one or more processors, a photo-realistic image of the infrastructure comprising the image data selected. Other examples are described and claimed.

Abstract: Disclosed herein are binding moieties that comprise non-CDR loops for masking the binding of a binding molecule to its target and CDRs for binding bulk serum proteins. Conditionally active target binding proteins that contain the binding moieties are also provided. Cleavable linkers used in the conditionally active target binding proteins are also disclosed.

Abstract: A rekeyable lock cylinder with a cylinder body and a plug assembly. The lock cylinder includes a plurality of key followers and a corresponding plurality of racks disposed in the plug assembly. The lock cylinder includes, for example, a locking bar for blocking rotation of the plug assembly with respect to the cylinder body to prevent unlocking of the rekeyable lock cylinder with an unauthorized object. In some embodiments, the locking bar is configured such that torqueing the plug assembly with an unauthorized object applies force to the locking bar without translating such force to the plurality of racks. This type of arrangement enhances torque resistance of the lock cylinder against attempted forced entry.

Abstract: Compounds active on protein kinases are described, as well as methods of making and using such compounds to treat diseases and conditions associated with aberrant activity of protein kinases.

Abstract: Provided herein are EpCAM binding proteins, pharmaceutical compositions comprising such proteins or fragments thereof, as well as nucleic acids, recombinant expression vectors and host cells for making such EpCAM binding proteins. Also disclosed are methods of using the disclosed EpCAM binding proteins in the prevention, and/or treatment diseases, conditions and disorders.

Abstract: Provided herein are intermediates and processes useful for facile synthesis of compounds of Formula 2: wherein R1 is C(O)R2; R2 is alkyl optionally substituted with 1-5 halogens; G is phenyl or a 5-6 membered heteroaryl optionally substituted with 1-2 R3; and each R3 is independently C1-C6 alkyl, CN, C1-C6 alkyl-CN, 3-6 membered cycloalkyl, or 4-6 membered heterocycloalkyl.

Abstract: Provided herein are descriptions of extended-release immune cell binding protein comprising a masking peptide and cleavable linker, and the methods of using thereof. Also described is a pharmaceutical composition comprising a protein with a masking peptide and a cleavable linker, and the method of using thereof.

Abstract: The present disclosure is a screwdriver. A rotating seat includes a turntable and a plurality of locking blocks. A driving rod set includes a driving rod and a ratchet gear, and the ratchet gear is located in the turntable. A retaining set includes a tooth block and an elastic piece. The tooth block includes a plurality of teeth, and the elastic piece abuts a driving plate and the tooth block. A driving seat set includes a driving seat and a positioning set, and the positioning set includes a spring and a positioning piece. A locking block is inserted between the tooth block and the ratchet gear, so that the locking tooth is locked or separated from the ratchet gear.

Abstract: The present disclosure is a combined screwdriver. A handle includes a cavity. A rod is arranged in the cavity, and the rod includes a positioning part. A storage assembly includes a storage seat and a stopper seat, and the storage assembly is sleeved on the rod. The storage seat includes a sleeve and a plurality of elastic clips, the sleeve may move out of the cavity. An abutting piece is fixed on the positioning part, and the abutting piece includes a plurality of elastic pieces. The plurality of elastic pieces elastically abuts the sleeve, and a cap covers the cavity.

Abstract: A multifunctional hand tool has a grip and a metal working rod. The grip has an assembly hole. A polygonal coupling part is disposed on the assembly hole has. The metal working rod has two action sections, each action section has a polygonal portion, and each polygonal portion has an insertion hole. When one of the two action sections is inserted in the assembly hole, one of the two polygonal portions is engaged with the polygonal coupling part, the other action section is assembled to a suitable tool head, and a torque exerting element may be used to exert torque to the other polygonal portion or the insertion hole thereof. Accordingly, it is possible to provide versatility by having interchangeable tool heads on a top end and a bottom end of the metal working rod, and increasing torque on the top end and the bottom end.

Abstract: A ratchet wrench for rotating a workpiece with a top side includes a wrench body and a ratchet. The wrench body has a working end. The working end has a first end face and a second end face opposite to each other. The working end is disposed with a through hole. The ratchet is disposed in the through hole and formed with a first tool trough and a second tool trough communicating with each other. The first tool trough is arranged corresponding to the first end face and has a first blocking face. The second tool trough is arranged corresponding to the second end face and has a second blocking face. The workpiece is optionally received in the first tool trough or the second tool trough to make the top side abut against the first blocking face or the second blocking face.

Abstract: A hand tool includes a first and a second handles, a rotating locking set, a fastening set, and a spring. The first and second handles include chamfered planes respectively. The rotating locking set includes a rotating block and a locking block. The fastening set includes a stud and a nut. The spring is mounted around the stud and elastically abuts against the rotating block. The first handle or the second handle drives the rotating block to disengage from the locking block when being pulled by an external force. The first handle and the rotating block rotate with respect to the second handle by the stud as the center point. The rotating block and the locking block are locked with each other after rotating a specific angle, so as to position the first handle and the second handle.

Abstract: Compounds active on protein kinases are described, as well as methods of making and using such compounds to treat diseases and conditions associated with aberrant activity of protein kinases.

Abstract: Provided herein are intermediates and processes useful for facile synthesis of compounds of Formula 2: wherein R1 is C(O)R2; R2 is alkyl optionally substituted with 1-5 halogens; G is phenyl or a 5-6 membered heteroaryl optionally substituted with 1-2 R3; and each R3 is independently C1-C6 alkyl, CN, C1-C6 alkyl-CN, 3-6 membered cycloalkyl, or 4-6 membered heterocycloalkyl.

Abstract: The present disclosure is a combined screwdriver. A handle includes a cavity. A rod is arranged in the cavity, and the rod includes a positioning part. A storage assembly includes a storage seat and a stopper seat, and the storage assembly is sleeved on the rod. The storage seat includes a sleeve and a plurality of elastic clips, the sleeve may move out of the cavity. An abutting piece is fixed on the positioning part, and the abutting piece includes a plurality of elastic pieces. The plurality of elastic pieces elastically abuts the sleeve, and a cap covers the cavity.