Abstract: The compounds provided herein are phenyl analine amides and are useful for inhibiting histone deacteylase (“HDAC”) enzymes, such as HDAC1, HDAC2, and HDAC3.

Abstract: Premature termination codon readthrough prodrug compounds, compositions thereof, and methods of making and using the same are provided. In certain embodiments, the compounds are of Formula Ia or a pharmaceutically acceptable salt, solvate, polymorph, hydrate, ester, isomer, stereoisomer, or tautomer thereof, wherein R, A and W are as described herein.

Abstract: An integrated controller for an operator unit for powering an overhead garage roller door or roller shutter is described. The operator unit comprises a motor, an output drive assembly, a timing assembly unit, and a clutch assembly for providing selective engagement between motor powered operation and manual operation (provided by a chain rotating a chain wheel). The motor is arranged to drive a shaft which, in turn, provides drive to the roller door or shutter assembly (not shown), which includes an axle around which the roller door or shutter is wound. The integrated controller comprises an inverter for receiving a single phase power supply and supplying three phase power to drive the motor; and a drive controller in operable association with the inverter for providing active management of the operation of the motor.

Abstract: A helmet for tracking compliance information associated with a rider is disclosed. The helmet comprising a Global Positioning System (GPS) configured to trace a complete path covered by the rider. Further, the helmet comprises a set of biometric sensor configured to capture biometric sample of the rider at regular intervals, when the rider is in motion. Furthermore, the helmet comprises a data processing platform. The data processing platform maintains a database configured to store a profile data of the rider such as biometric information and identity profile of the rider. The data processing platform enables a biometric data analysis module configured to classify the complete path into a compliant path and a non-compliant path by analyzing the biometric information and biometric samples captured from the rider. Further, the data processing platform enables a data transmission module to transmit the compliant path and the non compliant path to a remote server.

Abstract: A radar device is provided that includes a timing control component operable to generate, for each chirp of a sequence of chirps according to a set of chirp configuration parameters and a chirp profile for the chirp, chirp control signals to cause the radar device to transmit the chirp, the timing control component having chirp configuration parameter inputs, chirp profile parameter inputs, a chirp address output, and chirp control signal outputs, a chirp configuration storage component having chirp configuration parameter outputs coupled to corresponding inputs of the configuration parameter inputs of the timing control component, a chirp profile address output, and a chirp address input coupled to the chirp address output, and a chirp profile storage component having chirp profile parameter outputs coupled to the chirp profile parameter inputs of the timing control component; and a chirp profile address input coupled to the chirp profile address output.

Abstract: 2,4-Diaminoquinazolines of formulae I-IV and VI are useful for treating spinal muscular atrophy (SMA).

Abstract: A cascaded radar system is provided that includes a first radar system-on-a-chip (SOC) operable to perform an initial portion of signal processing for object detection on digital beat signals generated by multiple receive channels of the radar SOC, a second radar SOC operable to perform the initial portion of signal processing for object detection on digital beat signals generated by multiple receive channels in the radar SOC, and a processing unit coupled to the first radar SOC and the second radar SOC to receive results of the initial portion of signal processing from each radar SOC, the processing unit operable to perform a remaining portion of the signal processing for object detection using these results.

Abstract: Enhancing search capacity of Global Navigation Satellite System (GNSS) receivers. A method for searching satellite signals in a receiver includes performing a plurality of searches sequentially. The method also includes storing a result from each search of the plurality of searches in a consecutive section of a memory. Further, the method includes detecting free sections in the memory. The method also includes concatenating the free sections in the memory to yield a concatenated free section. Moreover, the method includes allocating the concatenated free section for performing an additional search.

Abstract: 2,4-Diaminoquinazolines of formulae I-IV and VI are useful for treating spinal muscular atrophy (SMA).

Abstract: This invention relates to generally inhibiting histone deacetylase (“HDAC”) enzymes (e.g., HDAC1, HDAC2, and HDAC3).

Abstract: Enhancing search capacity of Global Navigation Satellite System (GNSS) receivers. A method for searching satellite signals in a receiver includes performing a plurality of searches sequentially. The method also includes storing a result from each search of the plurality of searches in a consecutive section of a memory. Further, the method includes detecting free sections in the memory. The method also includes concatenating the free sections in the memory to yield a concatenated free section. Moreover, the method includes allocating the concatenated free section for performing an additional search.

Abstract: A GNSS receiver includes at least one buffer and at least one correlator block. The at least one buffer stores a plurality of samples corresponding to a received signal. The at least one correlator block includes a Doppler derotation block configured to perform Doppler derotation corresponding to at least one Doppler frequency on the plurality of samples, a register array configured to be loaded with the plurality of samples on Doppler derotation corresponding to a Doppler frequency of the at least one Doppler frequency, and a correlator engine configured to generate correlation results by correlating the plurality of samples in the register array with a plurality of code phases for at least one GNSS satellite. A presence of at least one GNSS satellite signal may be detected based on coherent accumulation and a non-coherent accumulation of the correlation results.

Abstract: Several methods and circuits configured to mitigate signal interference of at least one aggressor circuit operable on a first clock signal within an interfering frequency range of at least one victim circuit in an IC are disclosed. In an embodiment, a signal interference mitigation circuit is configured to be associated with the aggressor circuit and includes a clock divider circuit and a control circuit. The clock divider circuit is configured to generate the first clock signal based on a second clock signal and a division factor pattern. The control circuit is coupled with the clock divider circuit and configured to determine the division factor pattern and provide the division factor pattern to the clock divider circuit. The division factor pattern comprises a plurality of division factors selected randomly based on a plurality of random numbers, and is configured to control a throughput frequency associated with the signal interference mitigation circuit.

Abstract: This invention relates to generally inhibiting histone deacetylase (“HDAC”) enzymes (e.g., HDAC1, HDAC2, and HDAC3) using compounds of formula (I), wherein the substituents are as defined herein.

Abstract: Disclosed are various embodiments for a calendar-agnostic scheduling application. The scheduling application may communicate a request for availability to other instances of the scheduling application. The scheduling application may determine availability according to a query in the request for availability by applying the query to a calendar accessible via a calendar provider. Meetings may be scheduled according to the availability of users determined by the queries while maintaining agnosticism to the calendar providers of the users.

Abstract: The invention relates to substituted benzothiazoles, benzoxazoles—and their counterparts having pyridine and pyrimidine rings replacing the benzene ring—that are PDE4 inhibitors useful for treating stroke, myocardial infarct, and cardiovascular inflammatory conditions, to pharmaceutical compositions comprising these compounds, and to methods for the treatment of stroke, myocardial infarct, and cardiovascular inflammatory conditions in a mammal. The compounds have general formula I: in which A and B are carbocycles or heterocycles.

Abstract: Compounds of the formula: are disclosed. The compounds act as phosphodiesterase-4 modulators, and useful for treating stroke, myocardial infarct, and cardiovascular inflammatory conditions. Other embodiments are also disclosed.

Abstract: The present invention relates to a genus of biaryl compounds containing at least one further ring. The compounds are PDE4 inhibitors useful for the treatment and prevention of stroke, myocardial infarct and cardiovascular inflammatory diseases and disorders.

Abstract: The invention relates to substituted benzothiazoles, benzoxazoles—and their counterparts having pyridine and pyrimidine rings replacing the benzene ring—that are PDE4 inhibitors useful for treating stroke, myocardial infarct, and cardiovascular inflammatory conditions, to pharmaceutical compositions comprising these compounds, and to methods for the treatment of stroke, myocardial infarct, and cardiovascular inflammatory conditions in a mammal. The compounds have general formula I: in which A and B are carbocycles or heterocycles.

Abstract: The present invention relates to a genus of biaryl compounds containing at least one further ring. The compounds are PDE4 inhibitors useful for the treatment and prevention of stroke, myocardial infarct and cardiovascular inflammatory diseases and disorders.