Abstract: A static or non-moving part electric power generator achieved by a changing (fluctuating) magnetic field (flux) by passing a pulsating direct current (DC) through a coil of wire wound on either a magnet or any material capable of producing a magnetic field, which in turn induces an alternating current (AC) in an adjacent secondary coil winding, and wherein a portion of the AC produced is used in recharging a DC source.

Abstract: A digital system includes a spur calculator that computes harmonics of a frequency of a digital clock signal and that identities a harmonic that lies in a frequency band of operation of a radio frequency circuit. A duty cycle computation module receives the harmonic and computes a duty cycle for the harmonic. Further, a clock generator that is coupled to the duty cycle computation block generates a digital clock signal of the frequency and with the duty cycle such that amplitude of spur caused due to the harmonic is suppressed.

Abstract: According to an aspect of the present invention, each correlation block in a Global Navigation Satellite System (GNSS) receiver is designed to examine a certain number of consecutive samples of an input signal and a buffer is designed to store more than such number of samples. Due to such storing, each correlator may perform multiple correlations for the same set of received samples. According to another aspect, such searches may be performed without rotating a local code by controlling the specific samples provided as window samples. Thus, while performing Doppler searches, different frequencies can be searched using the same local code without rotation. While performing code phase searches, the window samples may start from different positions with the position determining the specific phase being searched.

Abstract: Two chemical genera of pyrazolylphenyl and pyrrolylphenyl derivatives are disclosed. They have the general formula: In these compounds ring (a) is a pyrazole or pyrrole; Q is selected from the group consisting of a direct bond, O, S, SO, SO2, NR1, CH2, CF2, and C(O); HET is a 4-7-membered saturated nitrogenous heterocycle; and taken together ZW is H or Z is (CH2)1-10 in which one or two (CH2) may optionally be replaced by —O—, —NR1—, —SO—, —S(O)2—, —C(?O)— or —C?O(NH)—; and W is hydrogen, acyl, hydroxyl, carboxyl, amino, carboxamido, aminoacyl, —COOalkyl, —CHO, heterocyclyl, substituted aryl or substituted heterocyclyl. The compounds are inhibitors of LTA4H (leukotriene A4 hydrolase). They are useful for the treatment and prevention and prophylaxis of inflammatory diseases and disorders.

Abstract: Provided herein are substituted aromatic compounds, which are tRNA synthetase inhibitors, and hence can be used as antimicrobial agents. Compounds described herein can be used for the treatment or prevention of a condition caused by or contributed to by gram positive, gram negative, anaerobic bacteria or fungal organisms, more particularly against bacterium, for example, Staphylococci, Enterococci, Streptococci, Haemophilus, Moraxalla, Escherichia, Chlamydia, Mycoplasm, Legionella, Mycobacterium, Helicobacter, Clostridium, Bacteroides, Corynebacterium, Bacillus or Enterobactericeae, and fungal organisms, for example, Aspergillus, Blastomyces, Candida, Coccidiodes, Cryptococcus, Epidermophyton, Hendersonula, Histoplasma, Microsporum, Paecilomyces, Paracoccidiodes, Pneumocystis, Trichophyton, or Trichosporium. Processes for the preparation of these compounds, pharmaceutical compositions thereof, and methods of treating microbial infections are also provided.

Abstract: A method for generating a registered image relative to a cardiac cycle and a respiratory cycle of a person is provided. The method includes generating a plurality of 2-D images of an anatomical region of the person. The method further includes generating a 3-D model of the anatomical region of the person. The 3-D model is associated with a predetermined phase of the cardiac cycle and a predetermined phase of the respiratory cycle. The method further includes selecting a first 2-D image from the plurality of 2-D images associated with the predetermined phase of the cardiac cycle and the predetermined phase of the respiratory cycle. The method further includes generating the registered image of the anatomical region utilizing the first 2-D image and the 3-D model. The method further includes storing the registered image in a memory device.

Abstract: Methods for displaying a location of a point of interest on a 3-D model of an anatomical region of a person are provided. In one exemplary embodiment, the method includes generating first and second 2-D images of the anatomical region utilizing an image acquisition system when an X-ray source of the image acquisition system is disposed at first and second positions, respectively, in a 3-D coordinate system of the image acquisition system. The method further includes selecting first and second points in the first and second 2-D images, respectively. The method further includes utilizing a triangulation technique utilizing the first and second points to determine a point of interest in a 3-D coordinate system of the 3-D model of the anatomical region.

Abstract: The present invention relates to a chemical genus of 3-(triaryl)-2-aminopropanol derivative inhibitors of LTA4H (leukotriene A4 hydrolase) useful for the treatment and prevention of inflammatory diseases and disorders.

Abstract: 2,4-Diaminoquinazolines of formula (I) are provided herein and are useful for treating spinal muscular atrophy (SMA).

Abstract: 2,4-Diaminoquinazolines of formulae I-IV and VI are useful for treating spinal muscular atrophy (SMA).

Abstract: The present invention provides, in part, GLK1 nucleic acid molecules and polypeptides that can be used to confer resistance to a pathogen in a plant. The present invention also provides methods of detecting disease resistance genes and plants.

Abstract: A Global Navigation Satellite System (GNSS) receiver provided according to an aspect of the present invention contains a buffer to store less than a number of samples spanning a code period of a received GNSS signal, with the samples being used by a correlator and a processor to perform various searches in the receiver. Due to the use of such smaller memory space in the buffer, the overall size of receivers may be reduced. According to another aspect of the present invention, the amount of storage provided for storing local code and carrier samples (used during correlation) is also reduced by dynamically generating the local code and carrier sample as required for generating partial correlation results.

Abstract: 2,4-Diaminoquinazolines of formulae I-IV and VI are useful for treating spinal muscular atrophy (SMA).

Abstract: Disclosed are methods for the prevention or treatment of tuberculosis in a subject infected with Mycobacterium tuberculosis by administering rhodanine derivatives of formula (I), as well as some novel such compounds. Other embodiments are also disclosed.

Abstract: The present invention relates to a chemical genus of biaryl nitrogen-attached heterocycles that are inhibitors of LTA4H (leukotriene A4 hydrolase). The compounds have the general formula They are useful for the treatment and prevention and prophylaxis of inflammatory diseases and disorders.

Abstract: The present invention provides compounds having formula (I) or (II): and pharmaceutically acceptable derivatives thereof, wherein m, p, R1, R2, R3 and R4 are as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof for the treatment of any of a number of diseases, disorders or conditions associated with HGF/SF or other cytokine activity.

Abstract: Peri-substituted, fused bicyclic ring carboxylic acids useful for the treatment or prophylaxis of a prostaglandin-mediated disease or condition are disclosed.

Abstract: The present invention relates to a chemical genus of biaryl nitrogen-attached heterocycles that are inhibitors of LTA4H (leukotriene A4 hydrolase). The compounds have the general formula: They are useful for the treatment and prevention and prophylaxis of inflammatory diseases and disorders.

Abstract: The present invention provides compounds having formula (I) or (II): and pharmaceutically acceptable derivatives thereof, wherein m, p, R1, R2, R3 and R4 are as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof for the treatment of any of a number of diseases, disorders or conditions associated with HGF/SF or other cytokine activity.

Abstract: The present invention relates to a genus of biaryl compounds containing at least one further ring. The compounds are PDE4 inhibitors useful for the treatment and prevention of stroke, myocardial infarct and cardiovascular inflammatory diseases and disorders.