Patents by Inventor Jean Denis
Jean Denis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11711033Abstract: The invention relates to a piezoelectric motor with bending travelling wave, comprising a rotary shaft (4) connected to a rotor (3), a piezoelectric element (2) attached to a vibrating stator (1), and a decoupling web (5) for attaching the vibrating stator to a mounting (7). The mounting (7) is mechanically connected to a base (9) by means of at least one deformable element (10) and at least one piezoelectric actuator (11), so that the support can be deformed angularly relative to the base in order to rotate the shaft when the vibrating stator is no longer electrically powered. The motor is particularly suitable for applications that require micrometre or nanometre accuracies, for example in positioning tools in industrial processes, precise medical robotics or optical applications.Type: GrantFiled: April 22, 2020Date of Patent: July 25, 2023Assignee: TELEMAQ SASInventors: Jean-Denis Sauzade, Florian Gourlay
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Publication number: 20230210733Abstract: This disclosure relates to translucent oral care compositions comprising one or more source(s) of zinc source and/or a stannous source. The translucent oral care composition can comprise one or more zinc and/or stannous ion source(s) in amounts effective to provide at least 28% soluble zinc and/or stannous as a fraction of the total zinc and/or stannous ion concentration in the composition; an abrasive (e.g., silica), wherein the abrasive has a refractive index of approximately 1.45 as measured in a 4% silica, 90% sorbitol/water solution; and an orally acceptable vehicle. Methods of using and of making these compositions is also disclosed herein.Type: ApplicationFiled: December 30, 2022Publication date: July 6, 2023Inventors: Jean DENIS, Robert D'AMBROGIO, Guofeng XU
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Publication number: 20230138092Abstract: Described herein are oral care compositions comprising an effective amount of a stannous ion source and a taurate surfactant (e.g., sodium methyl cocoyl taurate). In one aspect the compositions of the disclosure can be used for the treatment or reduction of erosive tooth demineralization, gingivitis, plaque, and dental caries.Type: ApplicationFiled: October 26, 2022Publication date: May 4, 2023Applicant: Colgate-Palmolive CompanyInventors: Robert D'AMBROGIO, Jean DENIS
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Patent number: 11593111Abstract: An apparatus and method are provided for inhibiting instruction manipulation. The apparatus has execution circuitry for performing data processing operations in response to a sequence of instructions from an instruction set, and decoder circuitry for decoding each instruction in the sequence in order to generate control signals for the execution circuitry. Each instruction comprises a plurality of instruction bits, and the decoder circuitry is arranged to perform a decode operation on each instruction to determine from the value of each instruction bit, and knowledge of the instruction set, the control signals to be issued to the execution circuitry in response to that instruction. An input path to the decoder circuitry comprises a set of wires over which the instruction bits of each instruction are provided.Type: GrantFiled: January 27, 2020Date of Patent: February 28, 2023Assignee: Arm LimitedInventors: Frederic Jean Denis Arsanto, Carlo Dario Fanara, Luca Scalabrino, Jean Sébastien Leroy
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Patent number: 11567958Abstract: Disclosed are systems, methods, and non-transitory computer-readable storage media for shared folder backed integrated workspaces. In some implementations, a content management system can provide a graphical user interface (GUI) that integrates communications and content management into a single user interface. The user interface can include mechanisms that allow a user to provide input to generate a new workspace. The user interface can provide a mechanism to allow a user to view conversations related to the workspace and/or content items associated with the workspace. The user interface can present representations of content items associated with the workspace and allow the user to provide input to generate, view, edit, and share content items associated with the workspace.Type: GrantFiled: February 27, 2016Date of Patent: January 31, 2023Assignee: Dropbox, Inc.Inventors: Sean Beausoleil, Matteus Pan, Jean-Denis Greze, Anthony DeVincenzi
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Publication number: 20220356459Abstract: The present invention relates to an isolated polypeptide having beta-lactamase activity and nucleic acid sequences encoding the polypeptide. The isolated polypeptide of the invention is a VIM-2 variant with improved properties such as improved protease stability, stability in intestinal medium, improved activity against one or more antibiotics, improved specific activity and/or improved production in a host cell.Type: ApplicationFiled: May 16, 2022Publication date: November 10, 2022Inventors: Jean De Gunzburg, Jean-Denis Docquier
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Patent number: 11492128Abstract: A method for de-icing or anti-icing an aircraft portion having at least one piezoelectric element fastened on the inner face of the aircraft portion includes, during a design phase of the aircraft portion, placing the piezoelectric element on an area of the aircraft portion to determine frequencies of resonance and increased dynamic coupling, and during the de-icing or anti-icing of the aircraft portion, the same piezoelectric element is excited according to the natural frequencies of the area.Type: GrantFiled: September 18, 2020Date of Patent: November 8, 2022Assignee: Safran NacellesInventors: Patrick Gonidec, Jean-Paul Rami, Hakim Maalioune, Rémi Billard, Vincent Rigolet, Jean-Denis Sauzade
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Publication number: 20220306606Abstract: Compounds of Formula I: pharmaceutically acceptable salts thereof, deuterated derivatives of any of the foregoing, and metabolites of any of the foregoing are disclosed. Pharmaceutical compositions comprising the same, methods of treating cystic fibrosis using the same, and methods for making the same are also disclosed.Type: ApplicationFiled: October 20, 2021Publication date: September 29, 2022Inventors: Timothy Alcacio, Minson Baek, Peter Grootenhuis, Sara Sabina Hadida Ruah, Robert M. Hughes, Ali Keshavarz-Shokri, Rachel McAuley-Aoki, Jason McCartney, Mark Thomas Miller, Fredrick Van Goor, Beili Zhang, Corey Anderson, Thomas Cleveland, Bryan A. Frieman, Haripada Khatuya, Pramod Virupax Joshi, Paul John Krenitsky, Vito Melillo, Fabrice Jean Denis Pierre, Andreas P. Termin, Johnny Uy, Jinglan Zhou, Alexander Russell Abela, Brett Bradley Busch, Prasuna Paraselli
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Patent number: 11453655Abstract: Compounds of Formula (I): pharmaceutically acceptable salts thereof, deuterated derivatives of any of the foregoing, and metabolites of any of the foregoing are disclosed. Pharmaceutical compositions comprising the same, methods of treating cystic fibrosis using the same, and methods for making the same are also disclosed. Also disclosed are solid state forms of Compound 1 and salts and solvates thereof.Type: GrantFiled: August 17, 2020Date of Patent: September 27, 2022Assignee: Vertex Pharmaceuticals IncorporatedInventors: Alexander Russell Abela, Timothy Alcacio, Corey Anderson, Paul Timothy Angell, Minson Baek, Jeremy J. Clemens, Thomas Cleveland, Lori Ann Ferris, Peter Diederik Jan Grootenhuis, Raymond Stanley Gross, Anton V. Gulevich, Sara Sabina Hadida Ruah, Clara Kuang-Ju Hsia, Robert M. Hughes, Pramod Virupax Joshi, Ping Kang, Ali Keshavarz-Shokri, Haripada Khatuya, Paul John Krenitsky, Jason McCartney, Mark Thomas Miller, Prasuna Paraselli, Fabrice Jean Denis Pierre, Yi Shi, Muna Shrestha, David Andrew Siesel, Kathy Stavropoulos, Andreas P. Termin, Fredrick F. Van Goor, Johnny Uy, Timothy John Young, Jinglan Zhou
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Patent number: 11449642Abstract: An electronic circuit includes a plurality of processing elements, a register bank, and a control circuit. The processing elements consume power by processing a plurality of operands to generate a plurality of result values. The register bank has a plurality of registers. The control circuit is configured to determine one or more unused processing elements among the processing elements by snooping one or more incoming operands and an instruction type, control routing of one or more random operands from the register bank to the unused processing elements, and control routing of a random result value generated by one of the unused processing elements into a trash register of the registers. The power consumed by the unused processing elements in the generation of the random result value and a write of the random result value into the trash register temporally blurs a total power consumed by the electronic circuit.Type: GrantFiled: September 4, 2020Date of Patent: September 20, 2022Assignee: Arm LimitedInventors: Carlo Dario Fanara, Frederic Jean Denis Arsanto, Luca Scalabrino
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Publication number: 20220292088Abstract: Disclosed are systems, methods, and non-transitory computer-readable storage media for shared folder backed integrated workspaces. In some implementations, a content management system can provide a graphical user interface (GUI) that integrates communications and content management into a single user interface. The user interface can include mechanisms that allow a user to provide input to generate a new workspace. The user interface can provide a mechanism to allow a user to view conversations related to the workspace and/or content items associated with the workspace. The user interface can present representations of content items associated with the workspace and allow the user to provide input to generate, view, edit, and share content items associated with the workspace.Type: ApplicationFiled: June 3, 2022Publication date: September 15, 2022Applicant: Dropbox, Inc.Inventors: Sean Beausoleil, Matteus Pan, Jean-Denis Greze, Anthony DeVincenzi, Maxwell Johnson, Jack Dubie, Colin Dunn
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Patent number: 11426407Abstract: The present invention features a compound of formula I: or a pharmaceutically acceptable salt thereof, where R1, R2, R3, W, X, Y, Z, n, o, p, and q are defined herein, for the treatment of CFTR mediated diseases, such as cystic fibrosis. The present invention also features pharmaceutical compositions, method of treating, and kits thereof.Type: GrantFiled: March 31, 2020Date of Patent: August 30, 2022Assignee: Vertex Pharmaceuticals IncorporatedInventors: Mark Thomas Miller, Corey Anderson, Vijayalaksmi Arumugam, Brian Richard Bear, Hayley Marie Binch, Jeremy J. Clemens, Thomas Cleveland, Erica Conroy, Timothy Richard Coon, Bryan A. Frieman, Peter Diederik Jan Grootenhuis, Raymond Stanley Gross, Sara Sabina Hadida-Ruah, Haripada Khatuya, Pramod Virupax Joshi, Paul John Krenitsky, Chun-Chieh Lin, Gulin Erdogan Marelius, Vito Melillo, Jason McCartney, Georgia McGaughey Nicholls, Fabrice Jean Denis Pierre, Alina Silina, Andreas P. Termin, Johnny Uy, Jinglan Zhou
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Patent number: 11414439Abstract: This disclosure provides modulators of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR), pharmaceutical compositions containing at least one such modulator, methods of treatment of cystic fibrosis by administering such modulators and pharmaceutical compositions, and processes for making such modulators.Type: GrantFiled: April 12, 2019Date of Patent: August 16, 2022Assignee: Vertex Pharmaceuticals IncorporatedInventors: Alexander Russell Abela, Jeremy J. Clemens, Peter Diederik Jan Grootenhuis, Sara Sabina Hadida Ruah, Yoshihiro Ishihara, Haripada Khatuya, Jason McCartney, Mark Thomas Miller, Fabrice Jean Denis Pierre, Joe Anh Tran, Jinglan Zhou
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Publication number: 20220235059Abstract: The present invention relates to compounds of formula (I) their salts and derivatives. Further object of the present invention are compositions, which comprise at least one compound of formula (I) or its pharmaceutically acceptable salts and derivatives and excipients and, optionally, a further active compound. Further object of the present invention are compounds of formula (I) or compositions which comprise them for use as antibacterial agents.Type: ApplicationFiled: June 4, 2020Publication date: July 28, 2022Applicant: Universita' degli Studi di SienaInventors: Federico Corelli, Antonella Brizzi, Claudia Mugnaini, Jean-Denis Docquier, Filomena Sannio
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Publication number: 20220202612Abstract: A device including a support (4) comprising a support base defining a spherical base contact surface, extending along a virtual sphere (S) and a circular rim extending in a rim plane; a first and a second needle mobile on the support between extracted and inserted positions in which the first and second needles are outside and maximally inserted in said virtual sphere, respectively, via first and second intermediate piercing positions in which, respectively, the first and second needles extend along first and second insertion axis and their tips are located on first and second insertion points belonging respectively to first and second hemispheres of the virtual sphere separated by a “median radial plane of the rim”, an angle (?) between the median radial plane and any insertion axis being between 70° and 110°.Type: ApplicationFiled: April 24, 2020Publication date: June 30, 2022Inventors: Jean-Denis Laffitte, Francine BEHAR-COHEN, Christophe MOUREAUX, François CABAUD, Jerome Joseph SCHAFER, Travis Michael CRAFT, Benjamin Lee KO, Jacob William SCHUBERT, Michael D. AULD
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Publication number: 20220209687Abstract: The invention relates to a piezoelectric motor with bending travelling wave, comprising a rotary shaft (4) connected to a rotor (3), a piezoelectric element (2) attached to a vibrating stator (1), and a decoupling web (5) for attaching the vibrating stator to a mounting (7). The mounting (7) is mechanically connected to a base (9) by means of at least one deformable element (10) and at least one piezoelectric actuator (11), so that the support can be deformed angularly relative to the base in order to rotate the shaft when the vibrating stator is no longer electrically powered. The motor is particularly suitable for applications that require micrometre or nanometre accuracies, for example in positioning tools in industrial processes, precise medical robotics or optical applications.Type: ApplicationFiled: April 22, 2020Publication date: June 30, 2022Inventors: Jean-Denis Sauzade, Florian Gourlay
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Patent number: 11369595Abstract: The present invention concerns a tryptophan metabolite chosen from kynurenic acid, anthranilic acid, quinolinic acid, picolinic acid, quinaldic acid and the mixtures of same or an enantiomer, diastereoisomer, hydrate, solvate, tautomer, racemic mixture or pharmaceutically acceptable salt of same, for use as a drug intended for increasing and/or maintaining muscle mass and/or strength in a mammal, and in particular intended for treating and/or preventing muscle atrophy in mammals and/or for promoting muscle growth in mammals doing exercise and aiming to increase muscle mass and/or quality and/or strength, for preventing the appearance of symptoms of sarcopenia or for rehabilitation following muscle loss and/or for improving recovery time after an intense physical effort.Type: GrantFiled: September 5, 2017Date of Patent: June 28, 2022Assignee: METABRAIN RESEARCHInventors: Sophie N. Raynal, Annick Audet, Valérie Autier, Christine Charon, Jean-Denis Durand, Micheline Kergoat
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Patent number: 11365403Abstract: The present invention relates to an isolated polypeptide having beta-lactamase activity and nucleic acid sequences encoding the polypeptide. The isolated polypeptide of the invention is a VIM-2 variant with improved properties such as improved protease stability, stability in intestinal medium, improved activity against one or more antibiotics, improved specific activity and/or improved production in a host cell.Type: GrantFiled: October 24, 2018Date of Patent: June 21, 2022Assignees: Da Volterra, BioasterInventors: Jean De Gunzburg, Jean-Denis Docquier
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Patent number: 11354328Abstract: Disclosed are systems, methods, and non-transitory computer-readable storage media for shared folder backed integrated workspaces. In some implementations, a content management system can provide a graphical user interface (GUI) that integrates communications and content management into a single user interface. The user interface can include mechanisms that allow a user to provide input to generate a new workspace. The user interface can provide a mechanism to allow a user to view conversations related to the workspace and/or content items associated with the workspace. The user interface can present representations of content items associated with the workspace and allow the user to provide input to generate, view, edit, and share content items associated with the workspace.Type: GrantFiled: April 1, 2021Date of Patent: June 7, 2022Assignee: Dropbox, Inc.Inventors: Sean Beausoleil, Matteus Pan, Jean-Denis Greze, Anthony DeVincenzi, Maxwell Johnson, Jack Dubie, Colin Dunn
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Patent number: 11347762Abstract: Disclosed are systems, methods, and non-transitory computer-readable storage media for shared folder backed integrated workspaces. In some implementations, a content management system can provide a graphical user interface (GUI) that integrates communications and content management into a single user interface. The user interface can include mechanisms that allow a user to provide input to generate a new workspace. The user interface can provide a mechanism to allow a user to view conversations related to the workspace and/or content items associated with the workspace. The user interface can present representations of content items associated with the workspace and allow the user to provide input to generate, view, edit, and share content items associated with the workspace.Type: GrantFiled: May 29, 2015Date of Patent: May 31, 2022Assignee: Dropbox, Inc.Inventors: Sean Beausoleil, Matteus Pan, Jean-Denis Greze, Anthony DeVincenzi