Abstract: Provided are a heterocyclic amide compound of general formula (I), a pharmaceutically acceptable salt thereof and a preparation method therefor, and the use of the compound in the preparation of a drug for treating diseases related to the activity of STING, in the preparation of an immunologic adjuvant, and in the preparation of a drug for activating STING.

Abstract: A computing device, a method, and a computer readable medium for transferring data objects predictively to reduce consumption of resources. In some embodiments, a computing device includes: a memory; and a processor coupled to the memory. The processor is configured to store data objects in a storage system. The storage system is a multi-tier storage system. Storage of the data objects includes: determining a future demand status for at least one data object stored in the storage system based on a set of access activity rules; and moving the at least one data object between tiers of the storage system in response to the determined future demand status being different from a current demand status of the at least one data object to reduce consumption of resources in which to store that data object.

Abstract: The present disclosure provides an experimental device for simulating the erosion of a tubing string caused by sand production. The experimental device includes an autoclave, a circulating assembly, a power assembly, a monitoring assembly, or a three-phase feeding assembly. The circulating assembly is sealed and arranged in the autoclave, the circulating assembly includes a circulation loop formed by straight pipes and elbows. The power assembly includes a pump arranged on the circulation loop. The monitoring assembly includes a flowmeter and a temperature and pressure sensor for detecting the circulation loop, and the temperature and pressure sensor is communicatively connected with a PC. The three-phase feeding assembly includes a feeding pipe that is in fluid communication with the circulation loop, and the feeding pipe is connected with one or more gas tanks, a sander feeder, and one or more liquid tanks, respectively.

Abstract: The present invention relates to a mannuronic diacid oligosaccharide composition, comprising a mannuronic diacid of Formula (III) or a pharmaceutically acceptable salt thereof, wherein n is an integer from 1 to 9, m is 0, 1 or 2, and m? is 0 or 1, and wherein the total weight of mannuronic diacids wherein n=1-5 is 80-95% of the total weight of the composition, and the ratio of the total weight of mannuronic diacids wherein n=1-3 to the total weight of mannuronic diacids wherein n=4-7 is between 1.0 and 3.5.

Abstract: A computing device may include a display, and a processor coupled to the display and configured to generate a GUI current screen on the display. The GUI current screen may include a first window and a second window docked to the first window, the second window overlapping the first window. The processor may be configured to determine an interaction region in the first window based upon user input in the first window, determine a ratio of overlap between the first window and the second window, and resize the second window based upon the ratio of overlap and so that the second window does not overlap the interaction region.

Abstract: The systems and methods discussed herein provide for intelligent identification of applications or tasks to be utilized or performed by a user based on a variety of variables that provide relevant context. In some implementations, applications may be pre-launched or instantiated prior to a user requesting to execute the application, reducing user experience latency and avoiding incorrect application launch. User behavior patterns, location, time of day, user events, etc. may be utilized to identify and recommend or pre-launch relevant applications that should or can be used at any given instance. In some implementations, deep linking may be used to pre-launch or suggest specific tasks to be performed within an application.

Abstract: A compound having Axl and c-Met kinase inhibitory activity, a preparation method therefor and an application thereof are provided. Specifically, provided herein are a compound having the structure represented by formula (I), a preparation method therefor and an application thereof in the preparation of a medication for the treatment and/or prevention of tumor-associated diseases and/or kinase-related diseases.

Abstract: The invention relates to a compound of formula (I): wherein variables are as defined in the specification. The compound is an inhibitor of an ERK kinase, e.g. ERK1 and/or ERK2 kinase. The invention also relates to the use of the compound and a method for preparing the compound, and a pharmaceutical composition containing the compound.

Abstract: The present application provides use of an algal proteoglycan extract and a composition comprising the same in treating or preventing tumor, pain, inflammation or diseases mediated by inflammatory factors.

Abstract: The present invention relates to an alginic oligosaccharic diacid composition comprising a mannuronic diacid of Formula (IV) or a pharmaceutically acceptable salt thereof, wherein n is an integer selected from 1 to 9, m is selected from 0, 1 or 2, m? is selected from 0 or 1, and wherein the total weight of alginic oligosaccharic diacid wherein n=1-5 accounts for more than 60% of the total weight of the composition; the total weight of guluronic acids accounts for less than 50% of the total weight of the composition.

Abstract: The present invention relates to novel tricyclic compounds that are AKR1C3 dependent KARS inhibitor, processes for their preparation, pharmaceutical compositions, and medicaments containing them, and their use in diseases and disorders mediated by an AKR1C3 dependent KARS inhibitor.

Abstract: Methods and systems for determining information of applications are described herein. A computing device may receive, from one or more client devices, data indicating application usage events. The computing device may determine, based on the data, popular applications that a target user regularly uses. The computing device may determine, based on the data, recommended applications that users similar to the target user regularly use. The computing device may determine, based on the popular applications and/or the recommended applications, a collection of applications for the target user. The collection of applications may be displayed on a user interface of a client device associated with the target user for expedited access of interested applications.

Abstract: Disclosed herein are embodiments of systems, methods, and products comprising a data power server for secure storage and retrieval of trade data. The server receives a request from a user to review or confirm one or more trade documents via a webserver. The server communicates with a connector grid server to retrieve the user's accessible documents. The connector grid server determines the electronic file IDs that are accessible to the user based on the accessibility policy. The server instructs a digital library server to download the electronic files containing the requested trade data. The digital library server retrieves and downloads the electronic files based on the file IDs. The webserver renders a GUI displaying the electronic files on an electronic client device operated by the user. Upon receiving the confirmation response from the user, the server instructs the digital library server to update the trade status.

Abstract: Methods and systems for performing real time digital content concealment are described herein. A computing device may, in response to detecting a user within view of an image capture device of a client device, perform a first type of text recognition on a first region of digital content and a second type of text recognition on a second region of the digital content, where the first type of text recognition is determined based on a first type of content items contained in the first region and the second type of text recognition is determined based on a second type of content items contained in the second region. Based at least in part on rules corresponding to the user, the computing device may determine content items within the digital content to be concealed, and may modify the digital content to conceal the content items.

Abstract: In some implementations, a method may involve determining first feature vectors for a plurality of data items accessed by a user of one or more client devices, the first feature vectors representing first contextual data about the one or more client devices at times that respective data items of the plurality of data items were accessed, the plurality of data items including a first data item. A predictive model, configured to classify input feature vectors into context types, may be used to determine that the first feature vector for the first data item is classified as a first context type. A second feature vector representing second contextual data about a first client device operated by the user may be determined and the predictive model may be used to determined that the second feature vector is classified as the first context type.

Abstract: A train door control method and system are provided. The train door control method includes: acquiring a first train identifier and a second train identifier when multiple trains park in a platform at the same time, a door of a first train to which the first train identifier belongs being to be opened at a current time point, and a second train to which the second train identifier belongs being a train arranged behind the first train, which enters the platform and parks in the platform; and controlling the opening and closing of the door of the first train and a door of the second train at different time points respectively according to the first train identifier and the second train identifier.

Abstract: The present invention relates to the application of mannuronic diacid oligosaccharide composition in the treatment of vascular dementia.

Abstract: The present invention relates to the use of mannuronic diacid oligosaccharide composition in the treatment of pain.

Abstract: The present invention relates to the use of mannuronic diacid oligosaccharide composition in the treatment of diabetes.

Abstract: The present invention relates to the use of mannuronic diacid oligosaccharide composition in the treatment of Parkinson's disease.