Abstract: The systems and methods discussed herein provide for intelligent identification of applications or tasks to be utilized or performed by a user based on a variety of variables that provide relevant context. In some implementations, applications may be pre-launched or instantiated prior to a user requesting to execute the application, reducing user experience latency and avoiding incorrect application launch. User behavior patterns, location, time of day, user events, etc. may be utilized to identify and recommend or pre-launch relevant applications that should or can be used at any given instance. In some implementations, deep linking may be used to pre-launch or suggest specific tasks to be performed within an application.

Abstract: The present invention provides a pyrido five-element aromatic ring compound, and a preparation method therefor and a use thereof. The compound provided in the present invention has an inhibitory effect on wild-type and/or mutant EZH2, and is well positioned to become a novel anti-tumor drug or a drug for the treatment of autoimmune diseases.

Abstract: A computer system is provided. The computer system includes a memory and at least one processor coupled to the memory and configured to detect open eyes in an image received from a camera of the computer; recognize properties of the open eyes including orientation, designation as a left or right eye, and relative position of the eyes; group the detected open eyes into pairs of eyes based on the recognized properties; measure pupillary distance (e.g. represented in image pixels) of each of the pairs of eyes; identify the pair of eyes associated with the largest pupillary distance as the eyes closest to the camera; calculate a relative distance from the camera to the closest pair of eyes, the relative distance calculated as a ratio of the camera focal length to the largest pupillary distance; and reduce brightness of the computer screen if the relative distance is less than a threshold ratio.

Abstract: The present invention relates to quinoline or quinazoline compound represented by the formula (I), a pharmaceutically acceptable salt thereof, a stereoisomer thereof, a prodrug molecule thereof, or a deuterated compound thereof. The compound of the present invention is effective in inhibiting the action of AXL protein kinase and can inhibit proliferation, migration, and invasion of various tumor cells. Further, the quinoline or quinazoline compound of the present invention has excellent metabolic stability, high in vivo antitumor activity, low toxic side effects, and can be used for preparing a drug for preventing hyperproliferative diseases such as tumors in humans and other mammals.

Abstract: The present disclosure provides a camera module and a mobile terminal. The camera module includes: a first camera, a second camera, an optical image stabilization (OIS) chip and a bracket. The first camera and the second camera are embedded in the bracket. A height from a top surface of a lens of the first camera to a bottom surface of the first camera is greater than a height from a top surface of a lens of the second camera to a bottom surface of the second camera. One end of the first camera away from the lens is provided with a first printed circuit board, and the first printed circuit board extends to an outside of the first camera and faces the second camera. The OIS chip is disposed on the first printed circuit board and faces the bottom surface of the second camera; the OIS chip is electrically connected to the first printed circuit board.

Abstract: The invention relates to a new method of preparing oligomannuronic diacids, important bioactives. The method utilizes oligomannuronic acids as starting materials and the target substances are obtained by acid degradation and active hypobromous acid oxidation steps. The method of preparing oligomannuronic diacids according to the invention employs moderate reaction conditions, has few side reactions, does not need further purification, achieves a yield of more than 90%, or even more than 95%, and is suitable for production with an on-line continuous reactor device, with reaction processes easy to implement automatic control.

Abstract: A reconfigurable joint track compound mobile robot has a main vehicle body, yaw joints and an auxiliary track module. The main vehicle body has a main track, and a clutch brake and a first wheel joint arranged in a main track driving wheel. A second wheel joint is arranged in a main track driven wheel. The main vehicle body is provided with main track driving mechanisms and a wheel joint driving mechanism. The main track driving wheel is driven to rotate by the main track driving mechanisms, which are connected with the clutch brake. The second wheel joint is driven to rotate by the wheel joint driving mechanism. Each wheel joint is correspondingly connected with the yaw joints, which are rotatably connected with the auxiliary track module. A yaw driving mechanism that drives the auxiliary track module to swing is arranged in each yaw joint.

Abstract: Typically, when a user switches sessions between devices, the user authenticates the sessions by providing user account information, password, and/or pin code input or other credentials. However, when the user is frequently switching sessions between devices, authenticating sessions may result in the user reducing or even stopping switching across mobile devices. Systems and methods according to this disclosure provide automatic session roaming across mobile devices using proximity authentication. Upon detecting an indication to initiate session roaming, the source device automatically roams the session on the source device to a target device based on a proximity of the source device to the target device. The session is handed off from the source device to the target device as an authenticated user session.

Abstract: Described embodiments provide a method, computer program product, and computer system for identifying a user that is proximate to a computing device. The age type of the user may be identified. It may be determined that content displayed on the computing device is not permitted for the age type of the user. Display of the content may be altered on the computing device based upon, at least in part, determining that the content displayed on the computing device is not permitted for the age type of the user.

Abstract: The invention provides an indolizine compound represented by formula I or a pharmaceutically acceptable salt thereof, a preparation method and a use thereof. The indolizine compound has an inhibitory effect on wild-type and/or mutant EZH2 or EZH1, and is expected to be developed into a novel drug for anti-tumor or for the treatment of autoimmune diseases.

Abstract: The present invention relates to a mannuronic diacid oligosaccharide composition, comprising a mannuronic diacid of Formula (III) or a pharmaceutically acceptable salt thereof, wherein n is an integer from 1 to 9, m is 0, 1 or 2, and m? is 0 or 1, and wherein the total weight of mannuronic diacids wherein n=1-5 is 80-95% of the total weight of the composition, and the ratio of the total weight of mannuronic diacids wherein n=1-3 to the total weight of mannuronic diacids wherein n=4-7 is between 1.0 and 3.5.

Abstract: The present application provides use of an algal proteoglycan extract and a composition comprising the same in treating or preventing tumor, pain, inflammation or diseases mediated by inflammatory factors.

Abstract: A method for blockchain generation is provided. The method includes: sending, by a client, transaction information to a first node device, where the transaction information includes basic information and digest information; receiving, by the client, an endorsement result sent by the first node device, where the endorsement result includes a signature generated after the first node device successfully performs transaction simulation; and if the endorsement result meets a preset transaction condition, sending, by the client, the digest information and the endorsement result to a second node device, so that the second node device sends, to the first node device the digest information to generate a complete blockchain. In this way, only the digest information is transmitted between the first node device and the second node device. Therefore, the second node device does not obtain the complete transaction information, so that information security is improved.

Abstract: The present application provides use of an algal proteoglycan extract and a composition comprising the same in treating or preventing tumor, pain, inflammation or diseases mediated by inflammatory factors.

Abstract: The present disclosure relates to a Pyrimido[5,4-b]indolizine or pyrimido[5,4-b]pyrrolizine compound, preparation method thereof and use thereof. The compounds of the present invention have good inhibitory activities against BTK at the molecular and cellular levels. Importantly, the compounds of the present invention have low activity against Ramos cells of normal human B lymphoma cells, and have high activity against BTK-sensitive human diffuse large B lymphoma TMD8 cells, indicating that these type of compounds with novel structural are highly selective, off-target phenomenon and corresponding side effects are low. Thus it is a selective inhibitor of BTK with development potential.

Abstract: The present application provides use of an algal proteoglycan extract and a composition comprising the same in treating or preventing tumor, pain, inflammation or diseases mediated by inflammatory factors.

Abstract: The invention describes an aryl-2,2?-tandem bisthiazole compound and a preparation method and the use thereof. In particular, disclosed in the present invention are an aryl-2,2?-tandem bisthiazole compound with the structure as shown in general formula I and the preparation method thereof and use thereof as a histone deacetylase inhibitor in the preparation of antitumor drugs.

Abstract: A soil measurement system is provided, comprising a soil surveying device, a radio receiver, a plurality of subterranean antennas, and a processor. The soil surveying device comprises a wireless radio transmitter configured to emit a wireless signal at a predetermined bandwidth in a predetermined spectrum. The plurality of subterranean antennas are in an array electronically connected to the radio receiver and configured to be mounted in a subterranean environment at different depths in the subterranean environment. Each of the plurality of subterranean antennas is configured to receive the wireless signal at a respective point in time. The processor is configured to determine a relative time of flight of the received wireless signal between the plurality of antennas at the respective point in time, and estimate a soil permittivity based on the determined relative time of flight. The measurement system may be applied to materials other than soil, in some examples.

Abstract: Provided are compositions and methods for treating cancer comprising the use of a immunoconjugate in combination with a cytotoxic agent or cytotoxic therapy. The immunoconjugate in combination with a cytotoxic agent or cytotoxic therapy shows synergistic effects in cancer treatment.

Abstract: Disclosed herein are embodiments of systems, methods, and products comprising a data power server for secure storage and retrieval of trade data. The server receives a request from a user to review or confirm one or more trade documents via a webserver. The server communicates with a connector grid server to retrieve the user's accessible documents. The connector grid server determines the electronic file IDs that are accessible to the user based on the accessibility policy. The server instructs a digital library server to download the electronic files containing the requested trade data. The digital library server retrieves and downloads the electronic files based on the file IDs. The webserver renders a GUI displaying the electronic files on an electronic client device operated by the user. Upon receiving the confirmation response from the user, the server instructs the digital library server to update the trade status.