Abstract: Provided is an anti-HER3 humanized monoclonal antibody. The antibody binds HER3 antigen, has high affinity and biological activity and low immunogenicity, and is stable in structure. The antibody can be used for preparing drugs for preventing or treating HER3-related diseases.

Abstract: A detection device includes a frame, a transport mechanism, detection mechanisms, and a grasping mechanism. The transport mechanism includes a feeding line, a first flow line, and a second flow line arranged in parallel on the frame. The detection mechanisms are arranged on the frame and located on two sides of the transport mechanism. The grasping mechanism is arranged on the frame and used to transport workpieces on the feeding line to the detection mechanisms, transport qualified workpieces to the first flow line, and transport unqualified workpieces to the second flow line.

Abstract: Provided are a centrifugal battery liquid injection mechanism and a liquid injection method thereof. The centrifugal battery liquid injection mechanism comprises a liquid injection device and a driving device, the liquid injection device is provided with a piston mechanism and a liquid outlet head capable of being opened and closed, and one end of the liquid injection device close to the liquid outlet head is further provided with a liquid injection port capable of being opened and closed; and the liquid injection port is used for injecting a wetting liquid into the liquid injection device. The liquid injection device is connected with a to-be-wetted device through the liquid outlet head, so as to inject the wetting liquid into the to-be-wetted device. The driving device is connected with the to-be-wetted device for driving the to-be-wetted device to move.

Abstract: Novel small molecule proteolysis-targeting chimeras (PROTACs) are provided, along with methods for their use as RIPK1 kinase degraders. The small molecule PROTACs described herein are useful in treating and/or preventing RIPK1 kinase-related diseases, such as cancer, neurodegenerative disorders, and inflammatory diseases. Also provided are methods for promoting RIPK1 kinase degradation in a cell using the compounds and compositions described herein.

Abstract: A method and apparatus for configuration and scheduling of sidelink resources for sidelink communications in a wireless communication network is disclosed. In one embodiment, a method performed by a first wireless communication device, includes: determining a sidelink resource unit in a sidelink resource set according to a resource aggregation level, wherein the sidelink resource unit in the sidelink resource set comprises a first number of first resource units in the time domain and a second number of second resource units in the frequency domain, and wherein the first number of the first resource units in the time domain is determined according to the resource aggregation level.

Abstract: A method and apparatus for configuration of sidelink channel resource units for sidelink communications in a wireless communication network is disclosed.

Abstract: A method for transmitting an application programming interface API request includes receiving, by a first API gateway, a first API request; obtaining, by the first API gateway, a first forwarding label corresponding to the first API request, where the first forwarding label includes a first target security domain identifier, and a security domain identifier of the first API gateway is different from the first target security domain identifier. The method also includes determining an address of a second API gateway according to a mapping relationship between the first target security domain identifier and the address of the second API gateway. The method additionally includes sending the first API request to the second API gateway based on the address which is a next-hop API gateway of the first API gateway that sends the first API request to an API gateway corresponding to the first target security domain identifier.

Abstract: A display panel includes a substrate and a grating disposed on a light-emitting side of the display panel. The grating includes a plurality of protruding portions and a plurality of interval portions, each interval portion is located between two adjacent protruding portions. The plurality of protruding portions are arranged on the substrate along a first direction, and each protruding portion extends along a second direction perpendicular to the first direction. Each protruding portion includes an outer surface and a bottom surface; the outer surface is a smooth curved surface, and the bottom surface is a flat surface. A cross-sectional figure of each protruding portion along a thickness direction of the display panel is a first figure; the first figure includes a curve and a bottom edge, and the first figure is a closed figure formed by the curve and the bottom edge.

Abstract: The disclosed embodiments include computerized methods, systems, and devices, including computer programs encoded on a computer storage medium, for generating terms of a search query based on a user's spoken utterances, identifying multiple cross-platform messages based on the generated terms, and to generating, via a presentation device, a single interface that enables the user to interact with identified messages. Based on a spoken utterance, the disclosed embodiments may determine user-specified search terms and/or criteria, and based on the user-specified search terms and/or criteria, may obtain cross-platform message data that corresponds to the search query. The communications device may generate one or more interface elements that describe corresponding ones of the cross-platform messages, which may be presented within a unified graphical user interface or voice-user interface by a communications device.

Abstract: Disclosed is an exercise bench. In the exercise bench, a resistance assembly arranged inside a machine body supplies resistance forces to two pull cables, and the two pull cables are respectively led out from shields on two sides of a deck and change their directions by two pull cable steering mechanisms.

Abstract: A rowing machine includes a rowing machine body, and further includes a fixing member, a deck fixedly connected to a lower portion of the rowing machine body, a receiving chamber opened in the fixing member, one end of the deck being rotatably connected to a lower end of the receiving chamber, and a size of the deck being identical to a size of the receiving chamber.

Abstract: Disclosed is a smart exercise apparatus equipped with electronic tags. The apparatus includes an exercise apparatus and an accessory. The exercise apparatus is provided with a reader, and the accessory is provided with an electronic tag, wherein the electronic tag is wirelessly connected to the reader. In the smart exercise apparatus, readers and electronic tags are respectively arranged on the exercise apparatus and the accessories thereof, such that the accessories are automatically identified in response to approaching the exercise apparatus.

Abstract: The present disclosure relates to a smart exercise apparatus. The apparatus includes two pull cables each having a free end, and damping mechanisms configured to supply damping forces to the pull cables; and further includes a mount, arms, and a display raisably and lowerably connected to the mount. The arms are detachably connected to the mount, and the height of the arms is adjustable. The free ends of the two pull cables are respectively led out from two ends of the arms.

Abstract: A front light module includes a light guide sheet and a light bar. The light guide sheet has two light receiving laterals, a fold line, a first pattern area, and a second pattern area respectively located on two sides of the fold line. One light receiving lateral is protruded to form first taper sets, and the other is protruded to form second taper sets. The second pattern area is superimposed on the first pattern area, and the first and second tapers set are engaged and coplanar to form a light incident surface after folding along the fold line. The light bar provides light toward the light incident surface, the first pattern area is lit by the odd positions of the light bar via the first taper sets, and the second pattern area is lit by the even positions of the light bar via the second taper sets.

Abstract: An integrated circuit includes an inductor that includes a first set of conductors in at least a first metal layer, and a guard ring enclosing the inductor. The guard ring includes a first conductor extending in a first direction, a second conductor extending in a second direction, and a first set of staggered conductors coupled to a first end of the first conductor and a first end of the second conductor. The first set of staggered conductors includes a second set of conductors in a second metal layer, a third set of conductors in a third metal layer and a first set of vias coupling the second set of conductors with the third set of conductors. The third metal layer is above the second metal layer. All metal lines in the second metal layer that are part of the guard ring extend in the first direction.

Abstract: Provided are a data transmission method and device and a storage medium. The data transmission method includes: indicating a reference resource set, where the reference resource set includes at least one reference resource, and the reference resource includes at least one of: a first type resource or a second type resource; and receiving feedback information for at least one reference resource in the reference resource set.

Abstract: Provided are a collaborative information sending method, a resource determination method, a communication node, and a storage medium. The collaborative information sending method includes acquiring condition information and sending collaborative information in the case where a target parameter satisfies the restriction of the condition information. The collaborative information includes a resource set.

Abstract: Provided is a conformation-specific antigen binding domain (ABD) specific for the Hedgehog receptor Patched1, which may be provided in the form of a nanobody. This nanobody potently activates the Hedgehog pathway in vitro and in vivo by stabilizing an alternative conformation of a Patched1 “switch helix”. This ABD or nanobody is water soluble, i.e. does not require lipid modifications for its activity, facilitating mechanistic studies of Hedgehog pathway activation and therapeutic use.

Abstract: The disclosed embodiments include computerized methods, systems, and devices, including computer programs encoded on a computer storage medium, for generating terms of a search query based on a user's spoken utterances, identifying multiple cross-platform messages based on the generated terms, and to generating, via a presentation device, a single interface that enables the user to interact with identified messages. Based on a spoken utterance, the disclosed embodiments may determine user-specified search terms and/or criteria, and based on the user-specified search terms and/or criteria, may obtain cross-platform message data that corresponds to the search query. The communications device may generate one or more interface elements that describe corresponding ones of the cross-platform messages, which may be presented within a unified graphical user interface or voice-user interface by a communications device.

Abstract: An electromagnetic component assembly includes a first magnetic core piece, a second magnetic core piece, and an inverted U-shaped conductive winding including a base section and first and second legs extending from base section. One of the first and second magnetic core pieces is configured to receive the base section. The first and second magnetic core pieces are gapped from one another to define a first gap, and one of the first and second magnetic core pieces includes a second gap that, in combination with the first gap, allows the component to be operated at more than one stable open circuit inductance (OCL) corresponding to different current loads.