Patents by Inventor Johannes Platzek

Johannes Platzek has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Protected 5,7-dihydroxy-4,4-dimethyl-3-oxoheptanoic acid esters and 5,7-dihydroxy-2-alkyl-4,4-dimethyl-3-oxoheptanoci acid esters for the synthesizing of epothilone and epothilone derivatives and process for the production of these esters
    Patent number: 7595418
    Abstract: This invention describes protected 5,7-dihydroxy-4,4-dimethyl-3-oxoheptanoic acid ester and 5,7-dihydroxy-2-alkyl-4,4-dimethyl-3-oxoheptanoic acid ester for the synthesis of epothilones and epothilone derivatives and process for the production of these esters.
    Type: Grant
    Filed: June 5, 2004
    Date of Patent: September 29, 2009
    Assignee: Bayer Schering Pharma Aktiengesellschaft
    Inventors: Juergen Westermann, Johannes Platzek, Orlin Petrov
  • PROCESS FOR PREPARING EPOTHILONE DERIVATIVES BY SELECTIVE CATALYTIC EPOXIDATION
    Publication number: 20080242868
    Abstract: The present invention describes a novel process for preparing an epothilone derivative using substituted pyridines and methyltrioxorhenium as catalyst.
    Type: Application
    Filed: March 27, 2008
    Publication date: October 2, 2008
    Inventors: Johannes PLATZEK, Orlin Petrov, Stephan Pruhs
  • METAL CHELATES HAVING A PERFLUORINATED PEG RADICAL, PROCESSES FOR THEIR PREPARATION, AND THEIR USE
    Publication number: 20080159954
    Abstract: The invention relates to the subjects characterized in the patent claims, namely metal chelates having a perfluorinated PEG radical, processes for their preparation, and their use, processes for their preparation and their use in NMR and X-ray diagnosis, radiodiagnosis and radiotherapy, and in MRT lymphography.
    Type: Application
    Filed: October 17, 2007
    Publication date: July 3, 2008
    Inventors: Johannes Platzek, Heiko Schirmer, Hanns-Joachim Weinmann, Bernd Misselwitz, Ludwig Zorn
  • PROTECTED 3,5-DIHYDROXY-2,2-DIMETHYL-VALEROAMIDES FOR THE SYNTHESIS OF EPOTHILONES AND DERIVATIVES AND PROCESS FOR THE PRODUCTION AND THE USE
    Publication number: 20080161580
    Abstract: The invention relates to new protected 3,5-dihydroxy-2,2-dimethyl-valeroamides for the synthesis of epothilones and derivatives and process for the production and the use of the new compounds for the production of epothilones or epothilone derivatives.
    Type: Application
    Filed: March 6, 2008
    Publication date: July 3, 2008
    Inventors: Jurgen Westermann, Johannes Platzek, Orlin Petrov
  • Trimeric, macrocyclically substituted halo-benzene derivatives
    Patent number: 7385054
    Abstract: The metal complexes of general formula I in which Hal stands for bromine or iodine, and A1 and A2 have different meanings, are suitable as contrast media.
    Type: Grant
    Filed: November 14, 2005
    Date of Patent: June 10, 2008
    Assignee: Schering AG
    Inventors: Johannes Platzek, Heiko Schirmer, Hanns-Joachim Weinmann, Jose Luis Martin, Juan R. Harto
  • NOVEL CHIRAL HEPTYNE DERIVATIVES FOR THE PREPARATION OF EPOTHILONES AND PROCESSES FOR THEIR PREPARATION
    Publication number: 20080108838
    Abstract: The invention relates to a new synthetic process for the production of key intermediates useful in the synthesis of epothilones or epothilone derivatives, to certain compounds used to produce these key intermediates and to a process to produce said compounds.
    Type: Application
    Filed: December 12, 2007
    Publication date: May 8, 2008
    Inventors: Johannes Platzek, Orlin Petrov, Marc Willuhn, Klaus Graske, Werner Skuballa
  • Protected 3,5-dihydroxy-2,2-dimethyl-valeroamides for the synthesis of epothilones and derivatives and process for production and the use
    Patent number: 7368568
    Abstract: The invention relates to new protected 3,5-dihydroxy-2,2-dimethyl-valeroarnides for the synthesis of edothilones and derivatives and process for the production and the use of the new compounds for the production of epothilones or epothilone derivatives.
    Type: Grant
    Filed: June 10, 2005
    Date of Patent: May 6, 2008
    Assignee: Bayer Schering Pharma AG
    Inventors: Jurgen Westermann, Johannes Platzek, Orlin Petrov
  • Protected 3,5-dihydroxy-2,2-dimethyl-valeronitriles for the synthesis of epothilones and epothilone derivatives and process for the production
    Patent number: 7358382
    Abstract: The invention relates to 3,5-dihydroxy-2,2-dimethyl-valeronitriles for the synthesis of epothilones and epothilone derivatives and process for the production of these new intermediate products in the synthesis and the use for the production of epothilones or epothilone derivatives.
    Type: Grant
    Filed: July 26, 2005
    Date of Patent: April 15, 2008
    Assignee: Bayer Schering Pharma AG
    Inventors: Jurgen Westermann, Johannes Platzek, Orlin Petrov
  • Process for the production of triiodotrimesic acid
    Patent number: 7355067
    Abstract: A new process for the production of triiodotrimesic acid that is used as an intermediate product for the synthesis of x-ray contrast media is described.
    Type: Grant
    Filed: December 1, 2006
    Date of Patent: April 8, 2008
    Assignee: Schering AG
    Inventors: Heiko Schirmer, Hannelore Niedballa, legal representative, Johannes Platzek, Jose Luis Martin, Juan R. Harto, Jose Carretero, Ulrich Niedballa
  • Use of perfluoroalkyl-containing metal complexes as contrast media in MR-imaging for visualization of intravascular thrombi
    Patent number: 7344704
    Abstract: The invention relates to the use of perfluoroalkyl-containing metal complexes that have a critical micelle formation concentration <10?3 mol/l, a hydrodynamic micelle diameter (2 Rh)>1 nm and a proton relaxivity in plasma (R1)>10 l/mmol·s as contrast media in MR imaging for visualization of intravascular thrombi.
    Type: Grant
    Filed: July 10, 2003
    Date of Patent: March 18, 2008
    Assignee: Schering AG
    Inventors: Bernd Misselwitz, Johannes Platzek, Yoko Kawata, Hanns-Joachim Weinmann, Takashi Yokawa, Ulrich Niedballa
  • Chiral heptyne derivatives for the preparation of epothilones and processes for their preparation
    Patent number: 7326798
    Abstract: The invention relates to a new synthetic process for the production of key intermediates useful in the synthesis of epothilones or epothilone derivatives, to certain compounds used to produce these key intermediates and to a process to produce said compounds.
    Type: Grant
    Filed: April 21, 2005
    Date of Patent: February 5, 2008
    Assignee: Schering AG
    Inventors: Johannes Platzek, Orlin Petrov, Marc Willuhn, Klaus Dieter Graske, Werner Skuballa
  • Synthesis of oxygen-substituted benzocycloheptenes as valuable intermediate products for the production of tissue-selective estrogens
    Patent number: 7321044
    Abstract: The invention relates to intermediate products and a new process for the production of benzocycloheptene C. The process for the production of its new intermediate products according to the invention starts from economical starting materials, provides the intermediate stages in high yields and high purity, without chromatographic purification steps, and allows production on an industrial scale.
    Type: Grant
    Filed: October 15, 2002
    Date of Patent: January 22, 2008
    Assignee: Schering Aktiengesellschaft
    Inventors: Johannes Platzek, Wolfgang Beckmann, Jens Geisler, Holger Kirstein, Ulrich Niedballa, Eckhard Ottow, Sigmar Radau, Claudia Schulz, Thomas Wessa
  • Protected 5,7-Dihydroxy-4,4-Dimethyl-3-Oxoheptanoic Acid Esters and 5,7-Dihydroxy-2-Alkyl-4,4-Dimethyl-3-Oxoheptanoci Acid Esters for the Synthesizing of Epothilone and Epothilone Derivatives and Process for the Production of These Esters
    Publication number: 20080015366
    Abstract: This invention describes protected 5,7-dihydroxy-4,4-dimethyl-3-oxoheptanoic acid ester and 5,7-dihydroxy-2-alkyl-4,4-dimethyl-3-oxoheptanoic acid ester for the synthesis of epothilones and epothilone derivatives and process for the production of these esters.
    Type: Application
    Filed: June 5, 2004
    Publication date: January 17, 2008
    Inventors: Juergen Westermann, Johannes Platzek, Orlin Petrov
  • Perfluoroalkyl-containing complexes, process for their production as well as their use
    Publication number: 20070189969
    Abstract: The invention relates to the subjects that are characterized in the claims, namely perfluoroalkyl-containing metal complexes with nitrogen-containing radicals of general formula I, process for their production and their use in NMR and x-ray diagnosis, radiodiagnosis, and radiotherapy, as well as in MRT lymphography and in blood-pool imaging.
    Type: Application
    Filed: July 17, 2006
    Publication date: August 16, 2007
    Inventors: Heiko Schirmer, Hanns-Joachim Weinmann, Johannes Platzek, Ludwig Zorn, Bernd Misselwitz, Joerg Meding, Heribert Schmitt-Willich, Thomas Brumby
  • Metal complexes that contain perfluoroalkyl, process for their production and their use in NMR diagnosis
    Patent number: 7226578
    Abstract: The invention relates to new, monomeric, perfluoroalkyl-substituted metal complexes, processes for their production, and their use in diagnosis and therapy. The compounds according to the invention are suitable especially as in vivo contrast media in nuclear spin tomography (MRT). They can preferably be used as blood-pool agents and as lymphographic agents.
    Type: Grant
    Filed: October 5, 2004
    Date of Patent: June 5, 2007
    Assignee: Shering aG
    Inventors: Johannes Platzek, Ulrich Niedballa, Bernd Radüchel, Wolfgang Schlecker, Hanns-Joachim Weinmann, Thomas Frenzel, Bernd Misselwitz, Wolfgang Ebert
  • Cascade polymer complexes, process for their production and pharmaceutical agents containing said complexes
    Patent number: 7211241
    Abstract: Described are new cascade polymer complexes, compositions containing them and use of the complexes in diagnosis and therapy, particularly for magnetic resonance imaging and computer tomography imaging.
    Type: Grant
    Filed: October 17, 2003
    Date of Patent: May 1, 2007
    Assignee: Schering Aktiengesellschaft
    Inventors: Heribert Schmitt-Willich, Johannes Platzek, Bernd Radüchel, Andreas Mühler, Thomas Frenzel
  • Process for the production of triiodotrimesic acid
    Publication number: 20070093674
    Abstract: A new process for the production of triiodotrimesic acid that is used as an intermediate product for the synthesis of x-ray contrast media is described.
    Type: Application
    Filed: December 1, 2006
    Publication date: April 26, 2007
    Inventors: Heiko Schirmer, Ulrich Niedballa, Hannelore Niedballa, Johannes Platzek, Jose Martin, Juan Harto, Jose Carretero
  • Cascade polymer bound complexing compounds, their complexes and conjugates, processes for their production, and pharmaceutical agents containing them
    Patent number: 7208139
    Abstract: Cascade polymers, containing complex-forming ligands, optionally at least five ions of an element of atomic numbers 21–29, 39, 42, 44 or 57–83, as well as, if desired, cations of inorganic and/or organic bases, amino acids or amino acid amides, are valuable complexing compounds and complexes for diagnostics and therapy.
    Type: Grant
    Filed: September 30, 2004
    Date of Patent: April 24, 2007
    Assignee: Schering AG
    Inventors: Johannes Platzek, Heribert Schmitt-Willich, Heinz Gries, Gabriele Schuhmann-Giampieri, Hubert Vogler, Hanns-Joachim Weinmann, Hans Bauer
  • Trimeric macrocyclic substituted benzene derivatives
    Patent number: 7208140
    Abstract: The metal complexes of general formula I in which Hal stands for bromine or iodine and A1 and A2 have different meanings, are suitable as contrast media.
    Type: Grant
    Filed: February 19, 2004
    Date of Patent: April 24, 2007
    Assignee: Schering Aktiengesellschaft
    Inventors: Heiko Schirmer, Hanns-Joachim Weinmann, Johannes Platzek, Jose Luis Martin, Juan R. Harto, Bjoern Riefke
  • Process for the production of dendritic trimesic acid triamides
    Patent number: 7199268
    Abstract: A new process for the production of dendritic trimesic acid triamides is described.
    Type: Grant
    Filed: December 16, 2004
    Date of Patent: April 3, 2007
    Assignee: Schering Aktiengesellschaft
    Inventors: Johannes Platzek, Klaus-Dieter Graske