Patents by Inventor Johannes Platzek

Johannes Platzek has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the production of perbenzylated 1-O-glycosides
    Patent number: 6545135
    Abstract: The invention relates to a process for the production of perbenzylated 1-O-glycosides of general formula I or salts thereof in which sugar1 is a monosaccharide that is functionalized in 1-OH-position, R represents benzyl, n means 2, 3 or 4, means —O—, —S—, —COO— or —NH— and L means a straight-chain, branched, saturated or unsaturated C1-C30 carbon chain, which optionally is interrupted or substituted by groups. The process according to the invention starts from economical starting materials, provides good yields and allows the production of perbenzylated saccharides with 1-O-functionalized side chains on an enlarged scale.
    Type: Grant
    Filed: March 8, 2001
    Date of Patent: April 8, 2003
    Assignee: Schering Aktiengesellschaft
    Inventors: Johannes Platzek, Ulrich Niedballa, Peter Mareski
  • Lipophilic metal complexes for necrosis and infarction imaging
    Publication number: 20030064026
    Abstract: This invention describes the use of metal complexes that have a plasma protein bond of at least 10% as imaging diagnostic agents for locating an infarction or a necrosis using lasting positive visualization.
    Type: Application
    Filed: October 7, 2002
    Publication date: April 3, 2003
    Applicant: Schering AG
    Inventors: Johannes Platzek, Ulrich Speck, Ulrich Niedballa, Bernd Raduchel, Hanns Weinmann, Wolfgang Ebert
  • Process for the production of perbenzylated 1-O-glycosides
    Publication number: 20030055242
    Abstract: The invention relates to a process for the production of perbenzylated 1-O-glycosides of general formula I or salts thereof 1
    Type: Application
    Filed: June 19, 2002
    Publication date: March 20, 2003
    Inventors: Johannes Platzek, Ulrich Niedballa, Klaus-Dieter Graske
  • Lipophilic metal complexes for necrosis and infarction imaging
    Patent number: 6495118
    Abstract: This invention describes the use of metal complexes that have a plasma protein bond of at least 10% as imaging diagnostic agents for locating an infarction or a necrosis using lasting positive visualization.
    Type: Grant
    Filed: September 24, 1998
    Date of Patent: December 17, 2002
    Assignee: Schering Aktiengesellschaft
    Inventors: Johannes Platzek, Ulrich Speck, Ulrich Niedballa, Bernd Radüchel, Hanns Joachim Weinmann, Wolfgang Ebert
  • Cascade polymer complexes, process for their production and pharmaceutical agents containing said complexes
    Publication number: 20020187101
    Abstract: Cascade polymer complexes with at least 16 ions of an element of atomic numbers 20 to 29, 39, 42, 44 or 57-83, useful NMR or x-ray lymphography imaging.
    Type: Application
    Filed: May 6, 2002
    Publication date: December 12, 2002
    Applicant: Schering AG
    Inventors: Heribert Schmitt-Willich, Johannes Platzek, Bernd Raduchel, Andreas Muhler, Thomas Frenzel
  • 1,4,7,10-tetraazacyclododecane butyltriols, processes for their production and pharmaceutical agents containing them
    Publication number: 20020176823
    Abstract: 1,4,7,10-Tetraazacyclodedecane butyltriols of general formula IA 1
    Type: Application
    Filed: April 9, 2002
    Publication date: November 28, 2002
    Inventors: Johannes Platzek, Heinz Gries, Hanns-Joachim Weinmann, Gabriele Schuhmann-Giampieri, Wolf-Rudiger Press
  • Process for the production of monoamides of DTPA
    Publication number: 20020155065
    Abstract: A new process for the preparation of diethylenetriaminepentaacetic-monoamides in which amines can be reacted with sensitive groups, a higher mono/diamide selectivity is achieved, a higher yield of monoamide is achieved and has a simple reaction scheme and working-up.
    Type: Application
    Filed: January 28, 2002
    Publication date: October 24, 2002
    Applicant: Schering AG
    Inventors: Johannes Platzek, Ulrich Niedballa
  • Metal complexes that contain perfluoroalkly, process for their production and their use in NMR diagnosis
    Patent number: 6468502
    Abstract: The invention relates to new, monomeric, perfluoroalkyl-substituted metal complexes, processes for their production, and their use in diagnosis and therapy. The compounds according to the invention are suitable especially as in vivo contrast media in nuclear spin tomography (MRT). They can preferably be used as blood-pool agents and as lymphographic agents.
    Type: Grant
    Filed: November 8, 1999
    Date of Patent: October 22, 2002
    Assignee: Schering Aktiengesellschaft
    Inventors: Johannes Platzek, Ulrich Niedballa, Bernd Radüchel, Wolfgang Schlecker, Hanns-Joachim Weinmann, Thomas Frenzel, Bernd Misselwitz, Wolfgang Ebert
  • Perfluoroalkylamides, their production and their use in diagnosis
    Patent number: 6461587
    Abstract: The invention relates to macrocyclic perfluoroalkylamides, their production and their use in diagnosis.
    Type: Grant
    Filed: March 22, 2000
    Date of Patent: October 8, 2002
    Assignee: Schering Aktiengesellschaft
    Inventors: Johannes Platzek, Ulrich Niedballa, Detlev Suelzle, Wolfgang Schlecker, Bernd Raduechel, Hanns-Joachim Weinmann, Thomas Frenzel, Bernd Misselwitz, Wolfgang Ebert
  • Lithium complexes of N-(1-hydroxymethyl-2,3-dihydroxypropyl)-1,4,7-triscarboxymethyl-1,4,7,10-tetraazacyclododecane, their production and use
    Publication number: 20020128472
    Abstract: The invention relates to crystalline lithium complexes of N-(1-hydroxymethyl-2,3-dihydroxypropyl)-1,4,7-triscarboxymethyl-1,4,7,10 tetraazacyclododecane, their production and the recovery of the salt-free gadolinium complex of N-(1-hydroxymethyl-2,3-dihydroxypropyl)-1,4,7-triscarboxymethyl-1,4,7,10 tetraazacyclododecane from the latter without the use of ion exchangers.
    Type: Application
    Filed: December 13, 2001
    Publication date: September 12, 2002
    Applicant: Schering AG
    Inventors: Johannes Platzek, Peter Blaszkiewicz, Orlin Petrov, Holger Hoffmann
  • Perfluoro-alkyl containing dye molecules and galencial formulations
    Patent number: 6447749
    Abstract: This invention describes galenical formulations that contain perfluoroalkyl-containing dye molecules and other perfluoroalkyl-containing substances. The new formulations are suitable as, i.a., contrast media for near-infrared diagnosis.
    Type: Grant
    Filed: September 29, 2000
    Date of Patent: September 10, 2002
    Assignees: Schering Aktiengesellschaft, Institut fuer Diagnostikforschung
    Inventors: Kai Licha, Andreas Becker, Bjoern Riefke, Johannes Platzek
  • Cascade polymer complexes, process for their production and pharmaceutical agents containing said complexes
    Patent number: 6426059
    Abstract: Cascade polmer complexes with at least 16 ions of an element of atomic numbers 20 to 29, 39, 42, 44 or 57-83, useful NMR or x-ray lymphography imaging.
    Type: Grant
    Filed: July 20, 2000
    Date of Patent: July 30, 2002
    Inventors: Heribert Schmitt-Willich, Johannes Platzek, Bernd Radüchel, Andreas Mühler, Thomas Frenzel
  • Perfluoroalkyl-containing complexes with sugar radicals, process for their production and their use
    Publication number: 20020076379
    Abstract: Perfluoroalkyl-containing complexes with sugar radicals of general formula I 1
    Type: Application
    Filed: August 10, 2001
    Publication date: June 20, 2002
    Applicant: Schering AG
    Inventors: Johannes Platzek, Peter Mareski, Ulrich Niedballa, Bernd Raduechel, Hanns-Joachim Weinmann, Bernd Misselwitz
  • CONJUGATES MADE OF METAL COMPLEXES AND OLIGONUCLEOTIDES, AGENTS CONTAINING THE CONJUGATES, THEIR USE IN RADIODIAGNOSIS AS WELL AS PROCESS FOR THEIR PRODUCTION
    Publication number: 20020077306
    Abstract: This invention relates to chemically modified oligo-nucleotide conjugates that contain a complexing agent or complex that is bound by a connecting component to the oligonucleotides. In this case, the oligonucleotides are modified in a way that prevents or at least significantly inhibits the degradation by naturally occurring nucleases. The oligonucleotide radical can bond specifically and with high bonding affinity to target structures and can thus produce a specific therapeutic or diagnostic effect by the bound complexing agent or complex.
    Type: Application
    Filed: June 7, 1995
    Publication date: June 20, 2002
    Inventors: LUDGER DINKELBORG, CHRISTOPH-STEPHAN HILGER, ULRICH NIEDBALLA, JOHANNES PLATZEK, BERND RADUECHEL, ULRICH SPECK, LARRY GOLD, WOLFGANG PIEKEN
  • Cascade polymer bound complexing compounds, their complexes and conjugates, process for their production, and pharmaceutical agents containing them
    Publication number: 20020068037
    Abstract: Cascade polymers, containing complex-forming ligands, optionally at least five ions of an element of atomic numbers 21-29, 39, 42, 44 or 57-83, as well as, if desired, cations of inorganic and/or organic bases, amino acids or amino acid amides, are valuable complexing compounds and complexes for diagnostics and therapy.
    Type: Application
    Filed: October 11, 2001
    Publication date: June 6, 2002
    Applicant: Schering AG
    Inventors: Johannes Platzek, Heribert Schmitt-Willich, Heinz Gries, Gabriele Schuhmann-Giampieri, Hubert Vogler, Hanns-Joachim Weinmann, Hans Bauer
  • 1,4,7,10-Tetraazacyclododecane butyltriols, processes for their production and pharmaceutical agents containing them
    Patent number: 6399043
    Abstract: 1,4,7,10-Tetraazacyclodedecane butyltriols of general formula IA in which R1 means hydrogen or a metal ion equivalent independent of one another and R2 means a butyltriol radical as well as their salts with organic or inorganic bases or amino acids are valuable pharmaceutical agents.
    Type: Grant
    Filed: July 23, 1999
    Date of Patent: June 4, 2002
    Assignee: Schering Aktiengesellschaft
    Inventors: Johannes Platzek, Heinz Gries, Hanns-Joachim Weinmann, Gabriele Schuhmann-Giampieri, Wolf-Rüdiger Press
  • Paramagnetic DOTA derivatives, pharmaceutical agents that contain the latter, process for their production, and their use for MR imaging of necrosis and infarction
    Publication number: 20020052354
    Abstract: The invention relates to compounds of general formula I
    Type: Application
    Filed: January 16, 2001
    Publication date: May 2, 2002
    Applicant: Schering AG
    Inventors: Johannes Platzek, Heribert Schmitt-Willich, Ulrich Niedballa, Hanns-Joachim Weinmann, Wolfgang Ebert
  • Process for the production of perbenzylated 1-0-glycosides
    Publication number: 20020002274
    Abstract: The invention relates to a process for the production of perbenzylated 1-O-glycosides of general formula I or salts thereof 1
    Type: Application
    Filed: March 8, 2001
    Publication date: January 3, 2002
    Applicant: SCHERING AKTIENGESELLSCHAFT
    Inventors: Johannes Platzek, Ulrich Niedballa, Peter Mareski
  • Cascade polymer bound complexing compounds, their complexes and conjugates, processes for their production, and pharmaceutical agents containing them
    Patent number: 6299859
    Abstract: Cascade polymers, containing complex-forming ligands, optionally at least five ions of an element of atomic numbers 21-29, 39, 42, 44 or 57-83, as well as, if desired, cations of inorganic and/or organic bases, amino acids or amino acid amides, are valuable complexing compounds and complexes for diagnostics and therapy.
    Type: Grant
    Filed: July 28, 2000
    Date of Patent: October 9, 2001
    Assignee: Schering Aktiengesellschaft
    Inventors: Johannes Platzek, Heribert Schmitt-Willich, Heinz Gries, Gabriele Schuhmann-Giampieri, Hubert Vogler, Hanns-Joachim Weinmann, Hans Bauer
  • Paramagnetic 3-,8-substituted deuteroporphyrin derivatives, pharmaceutical agents that contain the latter, process for their production, and their use for MR imaging of necrosis and infarction
    Patent number: 6251367
    Abstract: Paramagnetic 3-,8-substituted deuteroporphyrin derivatives with various substituents in positions 13 and 17 of the porphyrin skeleton, are suitable as diagnostic agents for MR imaging of necrosis and infarction.
    Type: Grant
    Filed: July 23, 1999
    Date of Patent: June 26, 2001
    Assignee: Schering Aktiengesellschaft
    Inventors: Johannes Platzek, Ulrich Niedballa, Bernd Raduechel