Patents by Inventor Johannes Platzek

Johannes Platzek has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Peroxynitrite rearrangement catalysts
    Publication number: 20040127479
    Abstract: The invention relates to the use of paramagnetic 3-, 8-substituted porphyrin derivatives with various substituents in 13- and 17-positions of the porphyrin skeleton as peroxynitrite rearrangement catalysts.
    Type: Application
    Filed: August 27, 2003
    Publication date: July 1, 2004
    Applicant: Merck Patent GmbH
    Inventors: Gisbert Depke, Margrit Hillmann, Guenter Michl, Johannes Platzek, Detlev Suelzle, Roland Neuhaus
  • Cascade polymer complexes, process for their production and pharmaceutical agents containing said complexes
    Publication number: 20040091426
    Abstract: Cascade polymer complexes that contain
    Type: Application
    Filed: October 17, 2003
    Publication date: May 13, 2004
    Inventors: Heribert Schmitt-Willich, Johannes Platzek, Bernd Raduchel, Andreas Muhler, Thomas Frenzel
  • Stents with a radioactive surface coating, processes for their production and their use for restenosis prophylaxis
    Patent number: 6709693
    Abstract: The invention relates to radioactive stents, characterized in that the stent is coated on the surface with the radioactive isotope, as well as processes for their production.
    Type: Grant
    Filed: July 27, 2000
    Date of Patent: March 23, 2004
    Assignee: Schering Aktiengesellschaft
    Inventors: Ludger Dinkelborg, Friedhelm Blume, Christoph-Stephan Hilger, Dieter Heldmann, Johannes Platzek, Ulrich Niedballa, Heribert Miklautz, Ulrich Speck, Stephan Duda, Gunnar Tepe, Bernhard Noll, Heidemarie Goerner
  • Perfluoroalkyl-containing complexes with polar radicals, process for their production and their use
    Patent number: 6676928
    Abstract: Perfluoroalkyl-containing complexes with polar radicals of general formula I (K)1-G-(Z-Rf)m(R)p  (I) in which R means the polar radical, Rf means a perfluorinated carbon chain, K is a metal complex, and Z represents a linker group, are suitable for intravenous lymphography, for tumor diagnosis and for infarction and necrosis imaging.
    Type: Grant
    Filed: August 10, 2001
    Date of Patent: January 13, 2004
    Assignee: Schering Aktiengesellschaft
    Inventors: Johannes Platzek, Peter Mareski, Ulrich Niedballa, Bernd Raduechel, Hanns-Joachim Weinmann, Bernd Misselwitz
  • Process for the production of monoamides of DTPA
    Patent number: 6677483
    Abstract: A new process for the preparation of diethylenetriaminepentaacetic-monoamides in which amines can be reacted with sensitive groups, a higher mono/diamide selectivity is achieved, a higher yield of monoamide is achieved and has a simple reaction scheme and working-up.
    Type: Grant
    Filed: January 28, 2002
    Date of Patent: January 13, 2004
    Assignee: Schering AG
    Inventors: Johannes Platzek, Ulrich Niedballa
  • Cascade polymer bound complexing compounds, their complexes and conjugates, processes for their production, and pharmaceutical agents containing them
    Publication number: 20030232017
    Abstract: Cascade polymers, containing complex-forming ligands, optionally at least five ions of an element of atomic numbers 21-29, 39, 42, 44 or 57-83, as well as, if desired, cations of inorganic and/or organic bases, amino acids or amino acid amides, are valuable complexing compounds and complexes for diagnostics and therapy.
    Type: Application
    Filed: December 11, 2002
    Publication date: December 18, 2003
    Inventors: Johannes Platzek, Heribert Schmitt-Willich, Heinz Gries, Gabriele Schuhmann-Giampieri, Hubert Vogler, Hanns-Joachim Weinmann, Hans Bauer
  • Metal complexes that contain perfluoroalkyl, process for their production and their use in NMR diagnosis
    Publication number: 20030232012
    Abstract: The invention relates to new, monomeric, perfluoroalkyl-substituted metal complexes, processes for their production, and their use in diagnosis and therapy.
    Type: Application
    Filed: July 18, 2002
    Publication date: December 18, 2003
    Applicant: Schering AG
    Inventors: Johannes Platzek, Ulrich Niedballa, Bernd Raduchel, Wolfgang Schlecker, Hanns-Joachim Weinmann, Thomas Frenzel, Bernd Misselwitz, Wolfgang Ebert
  • Conjugates of macrocyclic metal complexes with biomolecules and their use for the production of agents for NMR diagnosis and radiodiagnosis as well as radiotherapy
    Publication number: 20030206865
    Abstract: The invention relates to conjugates that consist of macrocyclic metal complexes with biomolecules and their production. The conjugates are suitable as contrast media in NMR diagnosis and radiodiagnosis as well as as agents for radiotherapy. High relaxivity is achieved by a special liganding of macrocyclic compounds, and a fine-tuning of the relaxivity is made possible.
    Type: Application
    Filed: July 19, 2002
    Publication date: November 6, 2003
    Applicant: Schering AG
    Inventors: Johannes Platzek, Heribert Schmitt-Willich, Gunther Michl, Thomas Frenzel, Detlev Sulzle, Hans Bauer, Bernd Raduchel, Hans-Joachim Weinmann, Henko Schirmer
  • Perfluoroalkyl-containing complexes with sugar radicals, process for their production and their use
    Patent number: 6641797
    Abstract: Perfluoroalkyl-containing complexes with sugar radicals of general formula I in which R represents a monosaccharide or oligosaccharide radical that is bonded via the 1-OH position or 1-SH position, Rf means a perfluorinated carbon chain, K is a metal complex, and Y and Z represent linker groups, are suitable for intravenous lymphography, for tumor diagnosis and for infarction and necrosis imaging.
    Type: Grant
    Filed: August 10, 2001
    Date of Patent: November 4, 2003
    Assignee: Schering Aktiengesellschaft
    Inventors: Johannes Platzek, Peter Mareski, Ulrich Niedballa, Bernd Raduechel, Hanns-Joachim Weinmann, Bernd Misselwitz
  • (Ethylene)-(propylene) - triaminepentaacetic acid derivatives, process for their production, and their use for the production of pharmaceutical agents
    Publication number: 20030194371
    Abstract: The invention relates to (ethylene)-(propylene)-triaminepentaacetic acid derivatives that are substituted on both the ethylene bridge and the propylene bridge, as well as conjugates of these compounds with biomolecules. The compounds and conjugates are suitable as agents for NMR diagnosis and radiodiagnosis as well as for radiotherapy.
    Type: Application
    Filed: July 10, 2002
    Publication date: October 16, 2003
    Applicant: Schering AG
    Inventors: Lutz Lehmann, Matthias Friebe, Christoph-Stephan Hilger, Ulrich Niedballa, Johannes Platzek, Bernd Raduchel
  • Synthesis of oxygen-substituted benzocycloheptenes as valuable intermediate products for the production of tissue-selective estrogens
    Publication number: 20030162974
    Abstract: The invention relates to intermediate products and a new process for the production of benzocycloheptene C.
    Type: Application
    Filed: October 15, 2002
    Publication date: August 28, 2003
    Applicant: Schering AG
    Inventors: Johannes Platzek, Wolfgang Beckmann, Jens Geisler, Holger Kirstein, Ulrich Niedballa, Eckhard Ottow, Sigmar Radau, Claudia Schulz, Thomas Wessa
  • Protected 3,5-dihydroxy-2,2-dimethyl-valeroamides for the synthesis of epothilones and derivatives and process for the production and the use
    Publication number: 20030158412
    Abstract: The invention relates to new protected 3,5-dihydroxy-2,2-dimethyl-valeroamides for the synthesis of epothilones and derivatives and process for the production and the use of the new compounds for the production of epothilones or epothilone derivatives.
    Type: Application
    Filed: August 5, 2002
    Publication date: August 21, 2003
    Applicant: Schering Aktiengesellschaft
    Inventors: Jurgen Westermann, Johannes Platzek, Orlin Petrov
  • Protected 3,-5-dihydroxy-2,2-dimethyl-valeronitriles for the synthesis of epothilones and epothilone derivatives and process for the production
    Publication number: 20030149281
    Abstract: The invention relates to 3,5-dihydroxy-2,2-dimethyl-valeronitriles for the synthesis of epothilones and epothilone derivatives and process for the production of these new intermediate products in the synthesis and the use for the production of epothilones or epothilone derivatives.
    Type: Application
    Filed: August 5, 2002
    Publication date: August 7, 2003
    Applicant: Schering AG
    Inventors: Jurgen Westermann, Johannes Platzek, Orlin Petrov
  • N-methyl-homocysteines and their use as well as process for their production
    Publication number: 20030120032
    Abstract: The synthesis of N-methyl-homocysteines and their use are described.
    Type: Application
    Filed: November 15, 2002
    Publication date: June 26, 2003
    Applicant: Schering AG
    Inventors: Marc Willuhn, Johannes Platzek, Eckhard Ottow, Orlin Petrov, Claudia Borm, Dirk Hinz, Gregor Mann, John Lister-James, David M. Wilson
  • Macrocyclic metal complexes and their use for the production of conjugates with biomolecules
    Publication number: 20030108486
    Abstract: The invention relates to macrocyclic metal complexes and their production and use for the production of conjugates with biomolecules. The conjugates are suitable as contrast media in NMR diagnosis and radiodiagnosis as well as for radiotherapy. High relaxivity is achieved by a special liganding of macrocyclic compounds, and a fine-tuning of the relaxivity is made possible.
    Type: Application
    Filed: July 19, 2002
    Publication date: June 12, 2003
    Applicant: Schering AG
    Inventors: Johannes Platzek, Heribert Schmitt-Willich, Gunther Michl, Thomas Frenzel, Detlev Sulzle, Hans Bauer, Bernd Raduchel, Hanns-Joachim Weinmann, Heiko Schirmer
  • Cascade polymer bound complexing compounds, their complexes and conjugates, process for their production and pharmaceutical agents containing them
    Patent number: 6576222
    Abstract: Cascade polymers, containing complex-forming ligands, optionally at least five ions of an element of atomic numbers 21-29, 39, 42, 44 or 57-83, as well as, if desired, cations of inorganic and/or organic bases, amino acids or amino acid amides, are valuable complexing compounds and complexes for diagnostics and therapy.
    Type: Grant
    Filed: October 11, 2001
    Date of Patent: June 10, 2003
    Assignee: Schering Aktiengesellschaft
    Inventors: Johannes Platzek, Heribert Schmitt-Willich, Heinz Gries, Gabriele Schuhmann-Giampieri, Hubert Vogler, Hanns-Joachim Weinmann, Hans Bauer
  • Galenical formulations
    Publication number: 20030095924
    Abstract: Abstract This invention describes galenical formulations that contain perfluoroalkyl-containing dye molecules and other perfluoroalkyl-containing substances. The new formulations are suitable as, i.a., contrast media for near-infrared diagnosis.
    Type: Application
    Filed: July 12, 2002
    Publication date: May 22, 2003
    Applicant: Schering Aktiengesellschaft
    Inventors: Kai Licha, Andreas Becker, Bjoern Riefke, Johannes Platzek
  • CALCIUM COMPLEX OF [[(4R)-4-[BIS{CARBOXY-.KAPPA.O)METHYL]AMINO-.KAPPA.N]-6,9-BIS[(CARBOXY.KAPPA.O)METHYL]-1-[(4,4-DIPHENYLCYCLOHEXYL)OXY]-1-HYDROXY-2-OXA-6,9-DIAZA-1-PHOSPHAUNDECAN-11-YLIC-ACID-.KAPPA.N6,.KAPPA.N9,.KAPPA.011]1-OXIDATO(6-)]-, HEXAHYDROGEN, ITS SALTS, PHARMACEUTICAL AGENTS THAT CONTAIN THESE COMPLEXES, THEIR USE IN TREATMENT AND AS ADDITIVES IN DIAGNOSIS, AS WELL AS PROCESSES FOR THE PRODUCTION OF THE COMPLEXES AND AGENTS
    Patent number: 6559330
    Abstract: The invention relates to the calcium complex of [[(4R)-4-[bis[(carboxy-.kappa.O)methyl]amino-.kappa.N]-6,9-bis[(carboxy-.kappa.O)methyl]-1-[(4,4-diphenylcyclohexyl)oxy]-1-hydroxy-2-oxa-6,9-diaza-1-phosphaundecan-11-ylic-acid-.kappa.N6,.kappa. N9,.kappa.011]1-oxidato(6-)]-, tetrahydrogen(MS-325) and its salts, pharmaceutical agents that contain these complexes, for the production of agents for the reduction of effects that are caused by heavy metals as well as processes for their production.
    Type: Grant
    Filed: September 11, 2000
    Date of Patent: May 6, 2003
    Assignee: Schering Aktiengesellschaft
    Inventors: Johannes Platzek, Ulrich Niedballa, Guenter Michl
  • Use of perfluoroalkyl-containing metal complexes as contrast media in MR-imaging for visualization of plaque, tumors and necroses
    Publication number: 20030072713
    Abstract: The invention relates to the use of perfluoroalkyl-containing metal complexes that have a critical micelle formation concentration <10−3 mol/l, a hydrodynamic micelle diameter (2 Rh)>1 nm and a proton relaxivity in plasma (R1)>10 l/mmol·s) as contrast media in MR imaging for visualization of plaque, lymph nodes, infarcted and necrotic tissue and for independent visualization of necrotic tissue and tumor tissue.
    Type: Application
    Filed: August 10, 2001
    Publication date: April 17, 2003
    Inventors: Johannes Platzek, Peter Mareski, Ulrich Niedballa, Bernd Raduechel, Hanns-Joachim Weinmann, Bernd Misselwitz
  • Process for the production of peracylated 1-0-glycosides
    Publication number: 20030069402
    Abstract: The invention relates to a process for the production of peracylated 1-O-glycosides of general formula I or salts thereof 1
    Type: Application
    Filed: July 11, 2002
    Publication date: April 10, 2003
    Applicant: Schering AG
    Inventors: Johannes Platzek, Klaus-Dieter Graske, Ulrich Niedballa