Abstract: Data processing apparatus comprises processing circuitry to apply processing operations to one or more data items of a linear array comprising a plurality, n, of data items at respective positions in the linear array, the processing circuitry being configured to access an array of n×n storage locations, where n is an integer greater than one, the processing circuitry comprising: instruction decoder circuitry to decode program instructions; and instruction processing circuitry to execute instructions decoded by the instruction decoder circuitry; wherein the instruction decoder circuitry is responsive to an array access instruction, to control the instruction processing circuitry to access, as a linear array, a set of n storage locations arranged in an array direction selected, under control of the array access instruction, from a set of candidate array directions comprising at least a first array direction and a second array direction different to the first array direction.

Abstract: Coated pharmaceutical packages are disclosed. The coated pharmaceutical packages may include a glass body formed from one of a borosilicate glass composition that meets Type 1 criteria according to USP <660> or an alkali aluminosilicate glass having a Class HGA 1 hydrolytic resistance when tested according to the ISO 720-1985 testing standard. A low-friction coating may be positioned on at least a portion of the first surface of the glass body the low-friction coating may include a polymer and a coupling agent disposed between the polymer and the first surface of the glass body. A coefficient of friction of the portion of the coated pharmaceutical package with the low-friction coating is at least 20% less than a coefficient of friction of a surface of an uncoated pharmaceutical package formed from the same glass composition.

Abstract: An apparatus comprises: an instruction decoder and processing circuitry. In response to a data structure processing instruction specifying at least one input data structure identifier and an output data structure identifier, the instruction decoder controls the processing circuitry to perform a processing operation on at least one input data structure to generate an output data structure. Each input/output data structure comprises an arrangement of data corresponding to a plurality of memory addresses. The apparatus comprises two or more sets of one or more data structure metadata registers, each set associated with a corresponding data structure identifier and designated to store address-indicating metadata for identifying the memory addresses for the data structure identified by the corresponding data structure identifier.

Abstract: Coated pharmaceutical packages may comprise a glass body formed from a borosilicate glass composition having a Type 1 chemical durability according to USP 660, the glass body having an interior surface and an exterior surface and a wall extending therebetween. A low-friction thermally stable coating having a thickness of ?1 ?m may be positioned on at least a portion of the exterior surface. The low-friction coating may comprise a silane. The portion of the exterior surface of the coated pharmaceutical package may have a coefficient of friction that is at least 20% less than an uncoated pharmaceutical package formed from the same borosilicate glass composition.

Abstract: Adoptive cell therapy involves the transfer of autologous or allogeneic cells to patients in an effort to treat a variety of diseases. In the area of immunotherapy, tumour specific T-cells can be grown ex vivo, or engrafted with tumour specificity via genetic engineering approaches, prior to reinfusion. T-cell infusions require a pre-conditioning treatment, and often a post infusion treatment of IL-2, in an effort to enhance persistence and engraftment. Herein Applicants show that T-cells can be engineered to express a Chimeric recombinant Growth Factor Receptor (CrGFR) which allows the selective survival and/or expansion of T-cells upon administration of a clinically available drug, Eltrombopag.

Abstract: A computer-implemented method and system for connecting authenticated persons, willing to pay for crowd-sourced answers to technical problems, to authenticated subject matter experts willing to sell answers to these problems in return for a variety of items of value; the system comprising a secure repository for questions posed by users and answers from other users, an innovation engine for selecting subject matter experts and facilitating collaborative solutions, a project governance engine configured to optimize the development path, a pricing engine to determine the market value of the answers, a marketplace engine for exchanging items and services of value, and means for users to communicate with other users or groups of users.

Abstract: A computing device is described. The computing device includes a first portion with a protrusion and a second portion separably connected to the first portion. The second portion has a receptacle. An undocking assist mechanism is configured to separate the first portion from the second portion when the protrusion is at least partially inserted into the receptacle. An actuator is configured to actuate the undocking assist mechanism. Methods of use are also described.

Abstract: An online system receives a discount offer from a merchant and displays the offers to users. Some of the discount offers provide for a discount that becomes valid when the discount offer is displayed to the user and remains valid for an offer duration. To implement these discount offers, a timestamp representing the time at which the discount offer is displayed is recorded and encoded. The encoded timestamp is provided to the merchant system when the user makes a purchase. The merchant extracts the recorded timestamp from the encoded timestamp and compares the recorded timestamp to the time of the purchase. If the time elapsed between the timestamp and the purchase is less than the offer duration, then the merchant system applies the discount to the purchase.

Abstract: Data processing apparatus comprises processing circuitry to selectively apply a vector processing operation to data items at positions within data vectors according to the states of a set of respective predicate flags associated with the positions, the data vectors having a data vector processing order, each data vector comprising a plurality of data items having a data item order, the processing circuitry comprising: instruction decoder circuitry to decode program instructions; and instruction processing circuitry to execute instructions decoded by the instruction decoder circuitry; wherein the instruction decoder circuitry is responsive to a propagation instruction to control the instruction processing circuitry to derive a set of predicate flags applicable to a current data vector in dependence upon a set of predicate flags applicable to a preceding data vector in the data vector processing order, wherein when one or more last-most predicate flags of the set applicable to the preceding data vector are inac

Abstract: A processing chamber such as a plasma etch chamber can perform deposition and etch operations, where byproducts of the deposition and etch operations can build up in a vacuum pump system fluidly coupled to the processing chamber. A vacuum pump system may have multiple roughing pumps so that etch gases can be diverted a roughing pump and deposition precursors can be diverted to another roughing pump. A divert line may route unused deposition precursors through a separate roughing pump. Deposition byproducts can be prevented from forming by incorporating one or more gas ejectors or venturi pumps at an outlet of a primary pump in a vacuum pump system. Cleaning operations, such as waferless automated cleaning operations, using certain clean chemistries may remove deposition byproducts before or after etch operations.

Abstract: A method includes receiving a spreadsheet application that is executable using a spreadsheet program; converting the spreadsheet application into a data file that defines characteristics of a networked version of the spreadsheet application that was converted from the spreadsheet application by applying permissions that are set in the spreadsheet application and not applied in the spreadsheet application, wherein the characteristics are defined based on the permissions and include information defining cells of the networked version of the spreadsheet application that are displayable to a user of the networked version of the spreadsheet application; and transmitting the data file to a server to make the data file available to network users as the networked version of the spreadsheet application.

Abstract: Coated pharmaceutical packages are disclosed. The coated pharmaceutical packages may include a glass body comprising a first surface and a second surface opposite the first surface. The glass body may be a glass container formed from a borosilicate glass composition and the first surface is an exterior surface of the glass container. A low-friction coating may be positioned on at least a portion of the first surface of the glass body. In embodiments, the low-friction coating may be a fluoropolymer.

Abstract: Systems are provided for a mounting assembly providing structural support to a pair of turbocharger and charge air coolers. In one example, the mounting assembly may include support brackets and pedestals for coupling the turbochargers and the charge air coolers to one structure. Separate channels for applying lubricant and coolant to the turbochargers and the charge air coolers may be coupled to the mounting assembly.

Abstract: Coated glass pharmaceutical packages are disclosed. According to embodiments, a coated glass pharmaceutical package may include a glass container formed from one of a borosilicate glass composition that meets Type 1 criteria according to USP <660> or an alkali aluminosilicate glass having a Class HGA 1 hydrolytic resistance when tested according to the ISO 720-1985 testing standard. A low-friction coating may be bonded to the exterior surface of the glass container. The low-friction coating may include a polymer. The exterior surface of the glass container with the low-friction coating may have a coefficient of friction of less than or equal to 0.7. The coated glass pharmaceutical package may be thermally stable after depyrogenation in air at a temperature of at least about 260° C. for 30 minutes.

Abstract: A vector data transfer instruction is provided for triggering a data transfer between storage locations corresponding to a contiguous block of addresses and multiple data elements of at least one vector register. The instruction specifies a start address of the contiguous block using a base register and an immediate offset value specifies as a multiple of the size of the contiguous block of addresses. This is useful for loop unrolling which can help to improve performance of vectorised code by combining multiple iterations of a loop into a single iteration of an unrolled loop, to reduce the loop control overhead.

Abstract: A cam follower assembly includes a cam roller, and a generally cylindrical body having an outer peripheral surface configured to be reciprocally slidable within a bore of an engine component. The cam roller is rotatably mounted on the body and configured to engage with a cam lobe on a camshaft of the engine. The cam lobe is operative to drive the body to a position at which the cam follower assembly causes one of opening of a valve or actuation of a fuel injector of the engine. A groove is formed in the body inset from the outer peripheral surface and extending axially along the outer peripheral surface parallel to the longitudinal axis of the body and aligned with an axial median plane of the cam roller and the cam lobe.

Abstract: A data processing system (2) supports vector processing operations performed upon vector operands comprising a plurality of vector operand elements. The data processing system includes a processor (4) having an instruction decoder (14) which decodes mixed-element-sized vector arithmetic instructions to generate control signals (16) which control processing circuitry (18) to perform arithmetic operations upon a first vector of first source operand elements ai of a first bit size A, and a second vector of second source operand elements bj of a second bit size B. The second bit size B is greater than the first bit size A.

Abstract: An online system receives a discount offer from a merchant and displays the offer to a user before the offer's start time. The online system also defines one or more triggering conditions and sends a notification to remind the user about the discount offer when a triggering condition is satisfied. One of the triggering conditions can be based on whether the user has accessed a web page provided by the merchant. The merchant system provides a web page that sends an indication to the online system when the user accesses the web page. After receiving the indication, the online system sends a notification about the discount offer to the user. Sending the notification in this manner has the effect of reminding the user of the discount offer after the user has already expressed an interest in the merchant and its products by viewing the merchant web page.

Abstract: A low-pressure hinge includes a plurality of segments with at least one upper frictional element and at least one lower frictional element where the at least one upper frictional element and the at least one lower frictional element are positioned on opposing sides of a segment of the plurality of segments. The hinge further includes a compression element that compresses the at least one upper frictional element and at least one lower frictional element against the segment with a compression force having a pressure less than 5,000 pounds per square inch.