Abstract: A free-standing wall includes concrete base blocks adjacent to each other forming a base course; a first set of concrete wall blocks stacked on the base course and on each other to form a first wall face; and a second set of concrete wall blocks stacked on the base course and on each other to form a second wall face that faces the opposite direction from the first wall face and that has the same number of courses as the first plurality of wall blocks. Methods of constructing the wall arrangement include laying the base blocks next to each other end to end; stacking individual blocks of a first set of blocks on the base course and then on each other to form a first wall face; stacking individual blocks of the second set of blocks on the base course and then on each other to form a second wall face that faces a direction opposite of the first wall face.

Abstract: A system for monitoring a plurality of tagged assets on at least one offshore asset, by creating a customer profile and a library of survey set ups and storing information from independent survey set ups mounted on or proximate to the offshore asset on the administrative data storage. The system includes creating a library of tagged assets for the offshore asset using at least one independent survey set up, wherein each tagged asset has an icon with a hyperlink to a library of images. The system includes identifying placement locations on offshore assets and forming an executive dashboard for display on at least one client device, wherein a virtually positioned icon positioned on an image of the tagged assets presents a hyperlink to the library of survey set ups for that tagged asset, thereby enabling toggling from the image to the library of survey set ups.

Abstract: The present invention discloses an assembly and process for creating a co-extruded pipe which includes the steps of extruding a first elongated component exhibiting an open interior. Additional process steps include co-extruding at least one, and typically a pair, of additional elongated components each having an arcuate or lobe cross sectional shape or profile. The additional components are bonded to exterior locations of the first component to establish a pair of additional open interiors between the components and prior to cooling and hardening.

Abstract: A continuous flow process for the oligomerization of ethylene using a chromium catalyst having a phosphorus-nitrogen-phosphorus (“P—N—P”) ligand provides high selectivity to the desired tetramer (1-octene) with reduced production of coproduct C10+ oligomers. Prior art processes that maximize catalyst activity have provided comparatively poor product selectivity. In particular, the production of larger amounts of C10+ oligomers have been observed under conditions that maximize activity. The present process resolves this problem through the use of a combination of low catalyst concentration and by limiting the octene concentration in the reactor.

Abstract: A foaming agent comprising an amount of soy whey protein is disclosed herein, the soy whey protein having been isolated from processing streams. The foaming agent is especially suitable for producing a food product.

Abstract: Systems and methods for generating three-dimensional models with correlated three-dimensional and two dimensional imagery data are provided. In particular, imagery data can be captured in two dimensions and three dimensions. Imagery data can be transformed into models. Two-dimensional data and three-dimensional data can be correlated within models. Two-dimensional data can be selected for display within a three-dimensional model. Modifications can be made to the three-dimensional model and can be displayed within a three-dimensional model or within two-dimensional data. Models can transition between two dimensional imagery data and three dimensional imagery data.

Abstract: By using a phage display derived peptide as an initial template, compounds have been developed that are highly specific against Mdm2/Mdm4. These compounds exhibit greater potency in p53 activation and protein-protein interaction assays than a compound derived from the p53 wild-type sequence. Unlike nutlin, a small molecule inhibitor of Mdm2/Mdm4, the phage derived compounds can arrest cells resistant to p53 induced apoptosis over a wide concentration range without cellular toxicity, suggesting they are highly suitable for cyclotherapy.

Abstract: An emulsifying agent comprising an amount of soy whey protein is disclosed herein, the soy whey protein having been isolated from processing streams. The emulsifying agent is especially suitable for producing a food product.

Abstract: A lighting device (10) having a base housing (12) to receive one or more batteries therein to power a light source located in a light housing (14). The light housing (14) being pivotally attached to the base housing (12) at pivot points on both sides of the base housing (12), wherein a handle (24) is provided which extends along the axis of rotation (13) between the pivot points.

Abstract: A portable lighting device adapted to provide an area light, said device including a body having a battery housing to hold batteries to power said device. The device includes a light panel functioning as a lens to act as an area light emitter, characterized in the said light panel is slidable into and out of said body, said light panel being constructed of a substantially flat panel portion.

Abstract: This invention relates to a process for the preparation of surface-functionalised metal oxide, metal sulphide, metal selenide or metal telluride nanoparticles, a process for the preparation of a composite material comprising such nanoparticles, nanoparticles and a composite material produced thereby, the use of such nanoparticles in catalysis and a catalyst comprising such nanoparticles.

Abstract: The present invention relates to modified eIF4G1 peptides, uses thereof and pharmaceutical compositions comprising the modified eIF4G1 peptides.

Abstract: A dynamic mixer comprising two mixing parts which are rotatable relative to each other about a predetermined axis of rotation, each of said mixing parts having a mixing face, between which is defined a flow path which extends between an inlet and an outlet, each of said mixing faces comprising a series of annular steps centred on the predetermined axis of rotation, having a plurality of offset and overlapping cavities formed therein, such that material moving between the mixing faces of the two mixing parts from the inlet to the outlet is transferable between overlapping cavities.

Abstract: The present invention relates to methods, agents and compound screening assays for inducing differentiation of undifferentiated mammalian cells into osteoblasts. The invention thus provides a method, comprising contacting a compound with a polypeptide comprising an amino acid sequence selected from the group consisting of SEQ ID No: 194-309; and measuring a compound-polypeptide property related to the differentiation of said cells. The invention further relates to a bone formation enhancing pharmaceutical composition, and the use thereof in treating and/or preventing a disease involving a systemic or local decrease in mean bone density in a subject. Furthermore, the invention relates to a method for the in vitro production of bone tissue.

Abstract: Certain chemical entities are provided herein. Also provided are pharmaceutical compositions comprising at least one chemical entity and one or more pharmaceutically acceptable vehicle. Methods of treating patients suffering from certain diseases and disorders responsive to the inhibition of KMO activity are described, which comprise administering to such patients an amount of at least one chemical entity effective to reduce signs or symptoms of the disease or disorder are disclosed. These diseases include neurodegenerative disorders such as Huntington's disease. Also described are methods of treatment include administering at least one chemical entity as a single active agent or administering at least one chemical entity in combination with one or more other therapeutic agents. Also provided are methods for screening compounds capable of inhibiting KMO activity.

Abstract: Certain chemical entities are provided herein. Also provided are pharmaceutical compositions comprising at least one chemical entity and one or more pharmaceutically acceptable vehicle. Methods of treating patients suffering from certain diseases and disorders responsive to the inhibition of KMO activity are described, which comprise administering to such patients an amount of at least one chemical entity effective to reduce signs or symptoms of the disease or disorder are disclosed. These diseases include neurodegenerative disorders such as Huntington's disease. Also described are methods of treatment include administering at least one chemical entity as a single active agent or administering at least one chemical entity in combination with one or more other therapeutic agents. Also provided are methods for screening compounds capable of inhibiting KMO activity.

Abstract: A method and system for establishing a wireless connection between a portable computer system and a wireless network, particularly when the portable computer system goes out of coverage and a wireless connection needs to be re-established. The portable computer system has a main processor and a digital signal processor (DSP). The main processor is placed in a low power mode, conserving battery power. When the portable computer system goes out of coverage, broadcast channels used by the wireless network are scanned by the DSP instead of the main processor to identify channels that have sufficient signal strength for the wireless connection. Thus, the main processor remains in the low power mode. When the DSP identifies acceptable channels, it wakes up the main processor and identifies the channels having sufficient signal strength. The main processor then establishes a wireless connection using one of the channels identified by the DSP.

Abstract: The present invention relates to compounds of formula (I) and to compositions comprising the same and to the use of the compounds and their compositions in treatment, for example in the treatment of inflammatory diseases, in particular respiratory inflammatory disease. The invention also extends to methods of making said compounds.

Abstract: Evacuation slide systems including a slide pack comprising a packboard coupled to an aircraft door, a girt bar coupled to an aircraft floor when the aircraft door is armed, and a restraint coupled to the packboard and the girt bar are detailed. The restraint controls a speed at which the aircraft door opens when the aircraft door is armed until the aircraft door has traveled beyond a predetermined distance.

Abstract: A method and system for establishing a wireless connection between a portable computer system and a wireless network, particularly when the portable computer system goes out of coverage and a wireless connection needs to be re-established. The portable computer system has a main processor and a digital signal processor (DSP). The main processor is placed in a low power mode, conserving battery power. When the portable computer system goes out of coverage, broadcast channels used by the wireless network are scanned by the DSP instead of the main processor to identify channels that have sufficient signal strength for the wireless connection. Thus, the main processor remains in the low power mode. When the DSP identifies acceptable channels, it wakes up the main processor and identifies the channels having sufficient signal strength. The main processor then establishes a wireless connection using one of the channels identified by the DSP.