Abstract: A monitoring system includes one or more units that are adapted monitor the radio frequency conditions of a facility or portion of the facility. The units include a packet sniffer and/or an RF spectrum analyzer. Sniffed packets and spectrum data are recorded and made available for analysis and display, either locally on the units or at one or more remote locations. The locations of the units are also gathered, thereby enabling correlation of the sniffed packets and/or RF spectrum data with locations within the facility. Real time RF conditions can thereby be gathered and used to improve the wireless communications within the facility and/or to ensure the wireless communication infrastructure of the facility is operating satisfactorily. The units may be person support apparatuses, such as beds, chairs, stretchers, cots, or the like.

Abstract: A foldable shoe includes a first sole section under the ball of a wearer's foot and includes a first outsole portion and a first footbed. A second sole section is located under the heel the foot and includes a second outsole portion and a second footbed. An upper section extends from the first sole section, and a hinge is connected to the first sole section and the second sole section and is configured to fold the foldable shoe from a first position, to be worn, to a second position, for storage. The upper section includes a first upper section connected to the first sole section and a second upper section connected to the second sole section. A connector connects the first upper section to the second upper section when the foldable shoe is in the first position and is disengaged when the foldable shoe is in the second position.

Abstract: There are provided methods and systems for making or repairing a specified part. For example, there is provided a method for creating an optimized manufacturing process to make or repair the specified part. The method includes receiving data from a plurality of sources, the data including as-designed, as-manufactured, as-simulated, as-inspected, as-operated, and as-tested data relative to one or more parts similar to the specified part. The method includes updating, in real time, a surrogate model corresponding with a physics-based model of the specified part, wherein the surrogate model forms a digital twin of the specified part. The method includes generating a prognostic model of predicted performance of the specified part based on the surrogate model and based on one or more characteristics of at least one of an additive and a reductive manufacturing process. The method includes executing, based on the digital twin, the optimized manufacturing process to either repair or make the specified part.

Abstract: An example of a kit includes a flow cell, a primer fluid, and a cleaving fluid. The flow cell includes at least one surface functionalized with a polymeric hydrogel including azide functional groups or amine functional groups. The primer fluid includes a plurality of alkyne-containing primers, each alkyne-containing primer having an amino cleavable group attaching a primer sequence of the alkyne-containing primer to an alkyne-containing moiety of the alkyne-containing primer. The cleaving fluid includes a substance that is reactive with the amino cleavable group.

Abstract: Embodiments relate to a device and method for determining a status of an environment and/or a status or condition of a person therein. The method may comprise: receiving an output of a sensor to monitor said environment; commencing a time window after the sensor detects activity in the environment; upon expiry of the time window, activating an active reflected wave detector to measure wave reflections from the environment, the detector consuming more power in an activated state than the sensor in an activated state; and determining a status of the environment and/or of a person therein based on an output of the active detector indicative of one or more of the measured reflections. The method comprises delaying expiry of the time window in response to the sensor detecting activity in the environment during the time window.

Abstract: There are provided methods and systems for making or repairing a specified part. For example, there is provided a method for creating a manufacturing process to make or repair the specified part. The method includes receiving data from a plurality of sources, the data including as-designed, as-manufactured, as-simulated, as-operated, as-inspected, and as-tested data relative to one or more parts similar to the specified part. The method includes updating, in real time, a surrogate model corresponding with a physics-based model of the specified part, wherein the surrogate model forms a digital twin of the specified part. The method includes generating a multi-variant distribution including component performance and manufacturing variance, the manufacturing variance being associated with at least one of an additive manufacturing process step and a reductive manufacturing process step.

Abstract: A device is provided that humidifies breathing gas. The device has a chamber with an inlet and an outlet. A chemical heater is positioned within the chamber and a trigger activates the heater. The chamber can be a conduit with an inner wall and an outer wall with a reservoir defined therebetween. The chemical heater can be positioned within the reservoir.

Abstract: The present invention relates to a sequencing method which allows for increased rates of sequencing and an increase in the density of sequencing data. The system may be based on next generation sequencing methods such as sequencing by synthesis (SBS) but uses multiple primers bound at different positions on the same nucleic acid strand.

Abstract: A method of compressing image data representing one or more images, the method including obtaining pixel data from the image data, the pixel data representing an pixel array within the one or more images, applying a transformation to the pixel data to determine a set of frequency coefficients indicative of frequency coefficients of the pixel array, encoding a selected subset of the set of frequency coefficients, generating an index indicative of the encoded frequency coefficients and generating compressed image data using the encoded frequency coefficients and the index.

Abstract: The present invention relates to compounds of Formula I that function as inhibitors of RET (rearranged during transfection) kinase enzyme activity: wherein HET, bonds a, b, c and d, X1, X2, X3, X4, R2, and R3 are each as defined herein. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of proliferative disorders, such as cancer, as well as other diseases or conditions in which RET kinase activity is implicated.

Abstract: A method of determining a duration of safe apnoea. Information is obtained relating to a respiratory indicator, which can include information relating to a potential respiratory equilibrium, and a duration of safe apnoea is determined from the obtained information.

Abstract: A closed loop control system for controlling a plant comprises a controller includes an input arranged to receive a feedback signal from the plant. The controller is arranged to compare a value of the feedback signal to a set point value x(s) and to produce an error signal ?(s) that is at least partially dependent on a difference between the value of the feedback signal and the set point value. The controller also includes an output arranged to supply the error signal ?(s) to the plant. A monitor is arranged to compare a value of the error signal ?(s) produced by the controller to a threshold value and to produce a warning signal when the value of the error signal ?(s) exceeds the threshold value for a period of time greater than a predetermined period.

Abstract: Dynamically generating data tests includes: receiving test templates and metadata for a plurality of data objects and, on a trigger condition: based on at least the metadata and the test templates, determining a current set of templated data tests, wherein determining the current set of templated data tests comprises: determining at least one templated data test, from a prior set of templated data tests, to cease using; determining at least one templated data test to add to the current set of templated data tests; and determining, within the current set of templated data tests, at least one templated data tests to regenerate; generating the at least one templated data test to add to the current set of templated data tests; regenerating the least one templated data test to regenerate; and executing templated data tests, within the set of current templated data tests, on the plurality of data objects.

Abstract: The present invention relates to compounds of formula I that function as inhibitors of RET (rearranged during transfection) kinase enzyme activity: wherein HET, bonds a, b, c and d, X1, X2, X3, X4, R2, and R3 are each as defined herein. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of proliferative disorders, such as cancer, as well as other diseases or conditions in which RET kinase activity is implicated.

Abstract: Herein provided is an interface for use in transmitting data from an aircraft including a first connector configured for physically and removably coupling a communication module to a communication system which obtains the data on-board the aircraft from at least one data source within the aircraft, and a second connector for digitally coupling the communication module to a processing unit of the communication module producing at least one message for transmission based on the data, the at least one message comprising information of interest identified based on the data. The interface is configured for conducting the at least one message from the processing unit to at least one radio via the second connector.

Abstract: A foldable shoe includes a first sole section located under the ball of a wearer's foot including a first outsole portion and a first footbed. The foldable shoe further includes a second sole section located under the heel of a wearer's foot, the second sole section including a second outsole portion and a second footbed. An upper section extends from the first sole section, and a hinge is connected to the first sole section and the second sole section and is configured to fold the foldable shoe from a first position, to be worn, to a second position, for storage. A first magnetic material disposed in the first sole section and a second magnetic material disposed in the second sole section creates a magnetic connection to retain the foldable shoe in first position or second position.

Abstract: A person support apparatus, such as a bed, cot, stretcher, or the like, includes an exit detection system that utilizes an occupant motion parameter to determine whether to issue an alert or not. The motion parameter may be based on the weight and motion of the occupant. Successive positions of the occupant are determined in order to calculate a velocity of the occupant. In some embodiments, the kinetic energy of the occupant is used to determine if an alert should be issued. Objects positioned on the person support apparatus may also be detected and tracked. Auto-zeroing of a built-in scale, as well as automatic recognition of the removal, movement, and/or addition of objects is also provided.

Abstract: A monitoring system includes one or more units that are adapted monitor the radio frequency conditions of a facility or portion of the facility. The units include a packet sniffer and/or an RF spectrum analyzer. Sniffed packets and spectrum data are recorded and made available for analysis and display, either locally on the units or at one or more remote locations. The locations of the units are also gathered, thereby enabling correlation of the sniffed packets and/or RF spectrum data with locations within the facility. Real time RF conditions can thereby be gathered and used to improve the wireless communications within the facility and/or to ensure the wireless communication infrastructure of the facility is operating satisfactorily. The units may be person support apparatuses, such as beds, chairs, stretchers, cots, or the like.

Abstract: Embodiments are directed at processing language content by a method of bi-directional conversion between language content with additional information to and from documents, using a readable text and a text grammar. A method combines additional information with the language content using punctuation idioms. The combined language content and additional information remains readable by one ordinarily skilled in the art of reading and also remains allowable according to a text grammar; that is embodiments are rigorous and may be declarative. The document is compliant with a format drawn from a set which comprises SGML, XML, TEI, HTML, DOC, DOCX, ODX, PDF and XPS. The document is publishable in a medium drawn from a set which comprises a book, a magazine, a journal, a newspaper, an article and a web page. A computer-readable memory device and a computing device are also claimed.