Abstract: Presented herein are recombinases for improved recombinase-mediated amplification of nucleic acids, such as a PCR-library having single-stranded adapter regions, on a patterned flow cell surface for improved cluster amplification, as well as methods and kits using the same.

Abstract: The mount allows an antenna to be fitted to an inaccessible side of a panel from an accessible side, through a knockout. An antenna and cable are first fitted to the mount. The mount has clips that can be squeezed inwards so that it can be inserted into the knockout, and then released so that they retain the mount from the far side of the panel. Stops on the mount prevent it from being inserted too far. The tabs may be squeezed with finger pressure only so that the mount can be fitted in restricted locations where access is difficult, such as in an electrical breaker box. The mount can easily be removed by squeezing the tabs.

Abstract: An apparatus and method for applying a chemistry to samples of interest are provided. The apparatus and method include a flexible tape mounted on an arrangement of guide rollers. Samples of interest (e.g., clusters of DNA templates) are bound to at least one surface of the flexible tape. The method and apparatus further comprise one or more read heads in relation to the flexible tape and a plurality of reservoirs along a path of the flexible tape. The reservoirs comprise liquids comprising chemical reagents for performing the chemistry on the samples of interest bound to the at least one surface of the flexible tape. The method and apparatus further comprise a drive system for driving at least one of the guide rollers to advance the flexible tape into and out of the reservoirs.

Abstract: A method including (a) providing an amplification reagent including an array of sites, and a solution having different target nucleic acids; and (b) reacting the amplification reagent to produce amplification sites each having a clonal population of amplicons from a target nucleic acid from the solution. The reacting can include simultaneously transporting the nucleic acids to the sites at an average transport rate, and amplifying the nucleic acids that transport to the sites at an average amplification rate, wherein the average amplification rate exceeds the average transport rate. The reacting can include producing a first amplicon from a nucleic acid that transports to each of the sites, and producing subsequent amplicons from the nucleic acid or from the first amplicon, wherein the average rate at which the subsequent amplicons are generated exceeds the average rate at which the first amplicon is generated.

Abstract: Systems and methods are disclosed for managing and storing electronic health records data. In an embodiment, a database module containing a plurality of databases stores a plurality of different types of patient medical data records. Each patient medical data record is composed of one or more categories of data which may be stored in different databases. A server module configured to respond to requests received from a client is connected to the database module. The server module includes a layer of application logic, a layer of composite services, a layer of domain services, and a layer of foundation services. A request received by the server module is first processed by the application logic, then by the appropriate composite services, domain services and foundation services. Domain services may communicate with the database module, generating a response that may be processed by the composite and application logic layers before sending back to the client.

Abstract: A bendable strap is disclosed which is configured to detachably couple with an accessory. The bendable strap includes a deformable support member covered by a flexible body. A coupling element is secured to the support member and cooperates with a complimentary coupling element disposed on an accessory such as a storage pouch, a tray, a hanger hook, a speaker enclosure, a flashlight, a picture frame, a message board, a bookstand, a beverage holder, or the like.

Abstract: Embodiments allow for the retrieval of information identifying the current context (patient being seen, medical record associated with the patient, or medical field selected) of a practice member. That information may be used as a key for subsequent API calls to match data submitted with records in an EHR system. In addition, a confidence level may be associated with that context. The confidence level may describe the level of confidence that context is correctly associated with that key.

Abstract: A system and method of operating a time and attendance apparatus receives biometric information; processes the biometric information to determine an identity of a current user of the apparatus and receives user input relating to time and attendance. The system/method further stores and/or transfers data based on the time and attendance user input to create or update a time and attendance record for the user; presents at least one further question to the user; receives further user input in response to the at least one further question, and stores and/or transfers data based on the further user input for creating or updating profile information for the user.

Abstract: A rollover prevention architecture for a vehicle comprising a reactive force member mounted on the vehicle, the reactive force member controlled to generate a counter torque relative to the direction of sensed tipping or rollover to mitigate the tipping or rollover of the vehicle while the vehicle is moving.

Abstract: Compounds of formula (I), described herein, exhibit human neutrophil elastase inhibitory properties, and are useful for the treatment of diseases and conditions in which HNE is implicated.

Abstract: The present disclosure relates to the field of molecular biology and more specifically to methods for capturing and amplifying target polynucleotides on a solid surface.

Abstract: In one embodiment, a utility vehicle includes a plurality of ground-engaging members configured to contact a ground surface, and a powertrain assembly operably coupled to the ground-engaging members. The utility vehicle also includes a frame supported by the ground-engaging members and extending along a longitudinal axis of the utility vehicle. The utility vehicle further includes a tunnel member coupled to the frame and extending along the longitudinal axis. The tunnel member is positioned at a first height from the ground surface. Additionally, the utility vehicle includes a cargo portion supported by the frame and positioned generally rearward of the tunnel member. The cargo portion has a cargo surface substantially aligned with the tunnel member and positioned at a second height from the ground surface. The first height is approximately equal to the second height.

Abstract: Compounds of formula (I): wherein R1, R2, R3, R5, R6, A1, A2, A3, A4 assume meanings as defined in formula (I) are inhibitors of neutrophil elastase.

Abstract: The present invention provides methods for creating an array of features on a surface based on content transferred from a plurality of beads to the surface. Nucleic acid content can be transferred using a method including the steps of (a) providing a surface having one or more primer oligonucleotides attached to the surface; (b) providing a pool of beads, wherein beads in the pool have a plurality of templates attached thereto, the plurality comprising multiple copies of a single nucleic acid template sequence; (c) arraying the beads onto the surface by hybridizing the templates to the primer oligonucleotides; and (d) extending the primers to produce copies of the templates attached to the surface.

Abstract: A fluid application system includes a diluent reservoir, a chemical container, a sprayer housing, a manifold located in the sprayer housing, and a pump assembly in fluid communication with an outlet of the manifold. The manifold includes a diluent inlet in fluid communication with the diluent reservoir, a chemical inlet in fluid communication with the container, a mixing chamber in fluid communication with the diluent inlet and the chemical inlet and the outlet of the manifold. The pump assembly draws a mixture of the chemical and the diluent from the manifold and sprays the mixture of the chemical and the diluent from the nozzle.

Abstract: A person support apparatus includes one or more thermal image sensors whose outputs are analyzed to perform one or more functions. Such functions include automatically turning on a brake, automatically turning on one or more lights, detecting when a patient associated with the person support apparatus has fallen, enabling a propulsion system of the patient support apparatus to be used, automatically controlling one or more environmental controls, and/or automatically arming an exit detection system after entry of a patient onto the person support apparatus. Multiple thermal images may be generated from multiple sensors to generate stereoscopic thermal images of portions of the person support apparatus and its surroundings.

Abstract: An automatic vehicle storage system includes an adjustable, self-guided vehicle satellite for moving a vehicle between a pick-up and drop-off bay, a vehicle carriage, and a storage bay. The vehicle carriage is typically movable along and by a vehicle crane, which carries the vehicle to a desired storage bay, where the vehicle satellite then moves the vehicle. Once the vehicle is in the storage bay, the satellite and returns back to the carriage at the vehicle crane. The vehicle storage system is also capable of rotating the vehicle, such that the vehicle is forward-facing in the pick-up and drop-off bay when it is retrieved by the user, and to facilitate the simultaneous operation of side-by-side cranes within a storage facility.

Abstract: Valve assembly for a pump, the valve assembly including: a valve seat having a valve face (60), a flexible valve having a sealing portion for abutting the valve face (60), and at least a fluid pathway (66, 68, 70) from an interior of the valve seat to an exterior of the valve seat that serves as a leak flow path for fluid when the valve is in the closed position to reduce pressure build up on the valve. In this way, the vacuum inside the pump can be released when the value is in the closed position and the pump is stopped, thereby allowing the pump to start/restart due to reduced pressure build up on a side of the valve abutting the valve face. A pump or compressor including such a valve assembly is also disclosed.