Abstract: Method to obtain methylene malonate and related monomers following a bis(hydroxymethyl) malonate pathway. A bis(hydroxymethyl) malonate intermediary is subsequently reacted (i.e., subjected to thermolysis) to provide a methylene malonate monomer species. A source of formaldehyde (e.g., formalin) is provided in the presence of a basic catalyst (e.g., calcium hydroxide), to which a malonate (e.g., diethyl malonate) is added under suitable reaction conditions to obtain the desired intermediary (e.g., dialkyl bis(hydroxymethyl) malonate). The intermediary is reacted (i.e., subjected to thermolysis) under suitable conditions in the presence of a suitable catalyst (e.g., a zeolite) to obtain a methylene malonate monomer. In an exemplary embodiment, the thermolysis reaction includes the addition of the bis(hydroxymethyl) malonate intermediary onto a heated catalyst. The reaction product is collected and purified. The disclosed methods may be performed in a continuous operation.

Abstract: Disclosed are compositions that comprise water and a polyether polyol derived from sucrose and an alkylene oxide, as well as polyurethane foam systems comprising such compositions, methods for their production, and the resulting polyurethane foams.

Abstract: Systems and methods for rescheduling passengers are provided. One example aspect of the present disclosure is directed to a method for rescheduling passengers. The method includes receiving an indication that an event has disrupted a plurality of flights. The method includes identifying a plurality of itineraries. The method includes determining a plurality of sets for the itineraries. The method includes determining a plurality of operations plan alternatives based on the plurality of sets. The method includes determining one or more constraints from the plurality of sets of itineraries. The method includes applying the one or more constraints to the plurality of operations plan alternatives to determine an impact of the one or more constraints to the plurality of operations plan alternatives on the sets of itineraries. The method includes determining an operations plan comprising a schedule for the plurality of flights.

Abstract: A bathroom fixture assembly comprising a plurality of rigid vertical members each comprising a first end configured to couple to a ceiling and a second end configured to extend downward beyond an upper edge of an outer wall of a basin of a bathtub or shower. The assembly may comprise a shower curtain channel configured to house a fully-functioning shower curtain. The assembly may further comprise one or more gates that may be used as grab bars and that may lock into position about a 180 degree range of motion around any of the rigid vertical members. The assembly may further comprise a seat, which may pivot from an upward position to a horizontal position when use is desired. The assembly may optionally comprise an exterior seat, cabinet, light, multi-use davit/hook, and/or physical therapy sky hook.

Abstract: A splittable honeycomb comprising: a first comb portion and a second comb portion comprising a first series of cell portions and a corresponding second series of cell portions respectively, said first and second cell portions defining a series of honeycomb cells therebetween, the first comb portion and the second comb portion being moveable relative to each other from a closed cell position to an open cell position, wherein mutually opposed edges of said cells are non-contiguous in the closed cell position to thereby avoid catching a limb of a bee.

Abstract: In an embodiment, a method of producing a carbonate comprises reacting carbon monoxide and chlorine in a phosgene reactor in the presence of a catalyst to produce a first product comprising phosgene; wherein carbon tetrachloride is present in the first product in an amount of 0 to 10 ppm by volume based on the total volume of phosgene; and reacting a monohydroxy compound with the phosgene to produce the carbonate; wherein the phosgene reactor comprises a tube, a shell, and a space located between the tube and the shell; wherein the tube comprises one or more of a mini-tube section and a second tube section; a first concentric tube concentrically located in the shell; a twisted tube; an internal scaffold; and an external scaffold.

Abstract: Disclosed herein are systems and methods related to reducing or making more efficient handovers from one cell to another cell in a communications network. The method includes receiving mobility data for a device being serviced by a first cell, classifying the device based on the mobility data to yield a classification and making a handoff decision when handing off the device from the first cell to a second cell based at least in part on the classification. An example of the mobility data is a speed at which the device is moving.

Abstract: In an embodiment, a method of producing carbonate can comprise: reacting a feed comprising carbon monoxide and chlorine in a tube of a reactor to produce a product composition comprising phosgene, wherein the tube has a particulate catalyst contained therein, wherein a thermally conductive material separate from the tube contacts at least a portion of the particulate catalyst, and wherein carbon tetrachloride is present in the product composition in an amount of 0 to 10 ppm by volume based on the volume of the phosgene; and reacting a monohydroxy compound with the phosgene to produce the carbonate.

Abstract: Method to obtain methylene malonate and related monomers following a bis(hydroxymethyl) malonate pathway. A bis(hydroxymethyl) malonate intermediary is subsequently reacted (i.e., subjected to thermolysis) to provide a methylene malonate monomer species. A source of formaldehyde (e.g., formalin) is provided in the presence of a basic catalyst (e.g., calcium hydroxide), to which a malonate (e.g., diethyl malonate) is added under suitable reaction conditions to obtain the desired intermediary (e.g., dialkyl bis(hydroxymethyl) malonate). The intermediary is reacted (i.e., subjected to thermolysis) under suitable conditions in the presence of a suitable catalyst (e.g., a zeolite) to obtain a methylene malonate monomer. In an exemplary embodiment, the thermolysis reaction includes the addition of the bis(hydroxymethyl) malonate intermediary onto a heated catalyst. The reaction product is collected and purified. The disclosed methods may be performed in a continuous operation.

Abstract: Disclosed are compositions that comprise water and a polyether polyol derived from sucrose and an alkylene oxide, as well as polyurethane foam systems comprising such compositions, methods for their production, and the resulting polyurethane foams.

Abstract: Recombinant lentiviral vectors containing at least: a lentiviral backbone comprising essential lentiviral sequences for integration into a target cell genome; a nucleic acid encoding a CCR5 RNAi; and an expression control element that regulates expression of the nucleic acid encoding the CCR5 RNAi element, are provided by this invention. In an alternative aspect, the vector also contains polynucleotides encoding TRIM5 alpha and HIV TAR decoy sequences along with gene expression regulation elements such as promoters operatively linked to the polynucleotides. The vectors are combined with packaging plasmid and envelope plasmids and optionally conjugated to cell-specific targeting antibodies. Diagnostic and therapeutic methods for using the compositions are further provided herein.

Abstract: In an embodiment, a method of producing a carbonate comprises reacting carbon monoxide and chlorine in a phosgene reactor in the presence of a catalyst to produce a first product comprising phosgene; wherein carbon tetrachloride is present in the first product in an amount of 0 to 10 ppm by volume based on the total volume of phosgene; and reacting a monohydroxy compound with the phosgene to produce the carbonate; wherein the phosgene reactor comprises a tube, a shell, and a space located between the tube and the shell; wherein the tube comprises one or more of a mini-tube section and a second tube section; a first concentric tube concentrically located in the shell; a twisted tube; an internal scaffold; and an external scaffold.

Abstract: Method to obtain methylene malonate and related monomers following a bis(hydroxymethyl) malonate pathway. A bis(hydroxymethyl) malonate intermediary is subsequently reacted (i.e., subjected to thermolysis) to provide a methylene malonate monomer species. A source of formaldehyde (e.g., formalin) is provided in the presence of a basic catalyst (e.g., calcium hydroxide), to which a malonate (e.g., diethyl malonate) is added under suitable reaction conditions to obtain the desired intermediary (e.g., dialkyl bis(hydroxymethyl) malonate). The intermediary is reacted (i.e., subjected to thermolysis) under suitable conditions in the presence of a suitable catalyst (e.g., a zeolite) to obtain a methylene malonate monomer. In an exemplary embodiment, the thermolysis reaction includes the addition of the bis(hydroxymethyl) malonate intermediary onto a heated catalyst. The reaction product is collected and purified. The disclosed methods may be performed in a continuous operation.

Abstract: In an embodiment, a method of producing carbonate can comprise: reacting a feed comprising carbon monoxide and chlorine in a tube of a reactor to produce a product composition comprising phosgene, wherein the tube has a particulate catalyst contained therein, wherein a thermally conductive material separate from the tube contacts at least a portion of the particulate catalyst, and wherein carbon tetrachloride is present in the product composition in an amount of 0 to 10 ppm by volume based on the volume of the phosgene; and reacting a monohydroxy compound with the phosgene to produce the carbonate.

Abstract: An airline operations system, controller and method reschedules flights affected by a disruption that precludes a planned schedule for the flights. The method includes obtaining data related to a scheduled origination and a scheduled destination for each of a set of passengers scheduled on the flights, generating a passenger connection network of connections between the scheduled origination and the scheduled destination for a subset of the set of passengers, applying at least one criterion to the passenger connection network and rescheduling at least one connecting flight based on the criteria. The system and controller solves a network flow problem to reschedule a subset of connecting flights to have a delayed projected departure time. Resulting output can include the set of delayed flights along with modified projected departure times, a set of flight cancellations and a set of passengers with missed connections.

Abstract: Disclosed herein are systems, computer-implemented methods, and tangible computer-readable media for placing an order for a user. The method includes receiving a search from a user, identifying a product category based on the search, presenting to the user a general ordering screen based on the identified product category, selecting and activating a speech recognition grammar tuned for the identified product category, recognizing a first received user utterance with the activated tuned grammar to identify a vendor who offers items in the identified product category, recognizing a second received user utterance with the activated tuned grammar to identify a specific item from the identified vendor, and placing an order for the specific item with the identified vendor for the user. In one aspect, the method further offers to sell the user additional items ancillary to the specific item.

Abstract: Disclosed herein are systems, computer-implemented methods, and tangible computer-readable media for placing an order for a user. The method includes receiving a search from a user, identifying a product category based on the search, presenting to the user a general ordering screen based on the identified product category, selecting and activating a speech recognition grammar tuned for the identified product category, recognizing a first received user utterance with the activated tuned grammar to identify a vendor who offers items in the identified product category, recognizing a second received user utterance with the activated tuned grammar to identify a specific item from the identified vendor, and placing an order for the specific item with the identified vendor for the user. In one aspect, the method further offers to sell the user additional items ancillary to the specific item.

Abstract: Recombinant lentiviral vectors containing at least: a lentiviral backbone comprising essential lentiviral sequences for integration into a target cell genome; a nucleic acid encoding a CCR5 RNAi; and an expression control element that regulates expression of the nucleic acid encoding the CCR5 RNAi element, are provided by this invention. In an alternative aspect, the vector also contains polynucleotides encoding TRIM5 alpha and HIV TAR decoy sequences along with gene expression regulation elements such as promoters operatively linked to the polynucleotides. The vectors are combined with packaging plasmid and envelope plasmids and optionally conjugated to cell-specific targeting antibodies. Diagnostic and therapeutic methods for using the compositions are further provided herein.

Abstract: Method to obtain methylene malonate and related monomers following a bis(hydroxymethyl) malonate pathway. A bis(hydroxymethyl) malonate intermediary is subsequently reacted (i.e., subjected to thermolysis) to provide a methylene malonate monomer species. A source of formaldehyde (e.g., formalin) is provided in the presence of a basic catalyst (e.g., calcium hydroxide), to which a malonate (e.g., diethyl malonate) is added under suitable reaction conditions to obtain the desired intermediary (e.g., dialkyl bis(hydroxymethyl) malonate). The intermediary is reacted (i.e., subjected to thermolysis) under suitable conditions in the presence of a suitable catalyst (e.g., a zeolite) to obtain a methylene malonate monomer. In an exemplary embodiment, the thermolysis reaction includes the addition of the bis(hydroxymethyl) malonate intermediary onto a heated catalyst. The reaction product is collected and purified. The disclosed methods may be performed in a continuous operation.