Patents by Inventor Karl J. Guegler

Karl J. Guegler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Proteins associated with EGF signaling
    Publication number: 20020106373
    Abstract: The invention provides human proteins associated with EGF signaling (PAWES) and polynucleotides which identify and encode PAWES. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of PAWES.
    Type: Application
    Filed: May 4, 2001
    Publication date: August 8, 2002
    Applicant: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Y. Tom Tang, Neil C. Corley, Karl J. Guegler, Henry Yue, Chandra Patterson
  • Human goose-type lysozyme
    Publication number: 20020106704
    Abstract: The invention provides a human goose-type lysozyme (GOLY) and polynucleotides which identify and encode GOLY. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of GOLY.
    Type: Application
    Filed: April 26, 2001
    Publication date: August 8, 2002
    Applicant: Incyte Pharmaceuticals, Inc.
    Inventors: Preeti Lal, Karl J. Guegler, Neil C. Corley, Chandra Patterson
  • Prostate growth-associated membrane proteins
    Publication number: 20020102585
    Abstract: The invention provides two human prostate growth-associated membrane proteins (PGAMP) and polynucleotides which identify and encode PGAMP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of PGAMP.
    Type: Application
    Filed: September 26, 2001
    Publication date: August 1, 2002
    Applicant: Incyte Pharmaceuticals, Inc.
    Inventors: Preeti Lal, Karl J. Guegler, Neil C. Corley
  • Thioredoxin proteins
    Publication number: 20020102654
    Abstract: The invention provides human thioredoxin proteins (TRXP) and polynucleotides which identify and encode TRXP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of TRXP.
    Type: Application
    Filed: September 17, 2001
    Publication date: August 1, 2002
    Applicant: Incyte Pharmaceuticals, Inc
    Inventors: Y. Tom Tang, Neil C. Corley, Karl J. Guegler, Chandra Patterson, Mariah R. Baughn
  • SH3-containing proteins
    Publication number: 20020102708
    Abstract: The invention provides a human SH3-containing protein (HS3C) and polynucleotides which identify and encode HS3C. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HS3C.
    Type: Application
    Filed: August 8, 2001
    Publication date: August 1, 2002
    Applicant: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Karl J. Guegler, Preeti Lal
  • Interferon-responsive protein
    Publication number: 20020103339
    Abstract: The invention provides human ISRE-binding protein (HIBP) and polynucleotides which identify and encode HIBP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of HIBP.
    Type: Application
    Filed: September 5, 2001
    Publication date: August 1, 2002
    Applicant: Incyte pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Preeti Lal, Neil C. Corley, Karl J. Guegler, Chandra Patterson, Mariah R. Baughn, Susan K. Sather, Purvi Shah
  • Prostate associated Ets protein
    Publication number: 20020098543
    Abstract: The invention provides a human prostate associated Ets protein (PRAEP) and polynucleotides which identify and encode PRAEP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of PRAEP.
    Type: Application
    Filed: May 24, 2001
    Publication date: July 25, 2002
    Applicant: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Karl J. Guegler, Preeti Lal, Neil C. Corley
  • Growth-associated protease inhibitor heavy chain precursor
    Publication number: 20020099178
    Abstract: The invention provides a human growth-associated protease inhibitor heavy chain precursor (GAPIP) and polynucleotides which identify and encode GAPIP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of GAPIP.
    Type: Application
    Filed: April 5, 2001
    Publication date: July 25, 2002
    Applicant: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Karl J. Guegler, Chandra Patterson
  • Human signal peptide-containing proteins
    Publication number: 20020091244
    Abstract: The invention provides a human signal peptide-containing proteins, the polynucleotides which encode them and methods for their use. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists.
    Type: Application
    Filed: March 5, 2001
    Publication date: July 11, 2002
    Applicant: Incyte Pharmaceuticals, Inc.
    Inventors: Preeti Lal, Jennifer L. Hillman, Neil C. Corley, Karl J. Guegler, Mariah R. Baughn, Susan K. Sather, Purvi Shah
  • Human ubiquitin-conjugating enzyme homologs
    Publication number: 20020086406
    Abstract: The invention provides human ubiquitin-conjugating enzyme homologs (UCEH) and polynucleotides which identify and encode UCEH. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of UCEH.
    Type: Application
    Filed: August 14, 2001
    Publication date: July 4, 2002
    Applicant: Incyte Pharmaceuticals, Inc.
    Inventors: Preeti Lal, Jennifer L. Hillman, Karl J. Guegler, Neil C. Corley, Mariah Baughn, Yalda Azimzai
  • Human protease molecules
    Publication number: 20020086334
    Abstract: The invention provides human protease molecules (HUPM) and polynucleotides which identify and encode HUPM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HUPM.
    Type: Application
    Filed: September 26, 2001
    Publication date: July 4, 2002
    Applicant: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Jennifer L. Hillman, Henry Yue, Karl J. Guegler, Neil C. Corley, Y. Tom Tang, Purvi Shah
  • Vacuolar proton ATPase subunits
    Publication number: 20020086394
    Abstract: The invention provides human vacuolar proton ATPase subunits (VATPS) and polynucleotides which identify and encode VATPS. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of VATPS.
    Type: Application
    Filed: October 1, 2001
    Publication date: July 4, 2002
    Applicant: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Y. Tom Tang, Preeti Lal, Neil C. Corley, Karl J. Guegler, Chandra Patterson
  • Protein kinase homologs
    Publication number: 20020081290
    Abstract: The invention provides human protein kinase homologs (PKH) and polynucleotides which identify and encode PKH. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of PKH.
    Type: Application
    Filed: May 30, 2001
    Publication date: June 27, 2002
    Applicant: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Y. Tom Tang, Jennifer L. Hillman, Henry Yue, Karl J. Guegler, Neil C. Corley, Gina A. Gorgone, Yalda Azimzai, Dyung Aina M. Lu
  • Human GTPase-associated proteins
    Patent number: 6410267
    Abstract: The invention provides human GTPase-associated proteins (GPAP) and polynucleotides which identify and encode GPAP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of GPAP.
    Type: Grant
    Filed: June 8, 2000
    Date of Patent: June 25, 2002
    Assignee: Incyte Genomics, Inc.
    Inventors: Olga Bandman, Preeti Lal, Karl J. Guegler, Neil C. Corley, Chandra Patterson
  • Human phospholipase A2 protein
    Patent number: 6399301
    Abstract: The invention provides a human phospholipase A2 protein PHPLA2 and polynucleotides which identify and encode PHPLA2. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of PHPLA2.
    Type: Grant
    Filed: January 21, 2000
    Date of Patent: June 4, 2002
    Assignee: Incyte Genomics, Inc.
    Inventors: Phillip R. Hawkins, Olga Bandman, Karl J. Guegler, Purvi Shah, Neil C. Gorley
  • HUMAN CARBOHYDRATE METABOLISM ENZYMES
    Publication number: 20020061301
    Abstract: The invention provides human carbohydrate metabolism enzymes (CARM) and polynucleotides which identify and encode CARM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of CARM.
    Type: Application
    Filed: May 15, 1998
    Publication date: May 23, 2002
    Inventors: OLGA BANDMAN, JENNIFER L. HILLMAN, PREETI LAL, KARL J. GUEGLER, GINA GORGONE, NEIL C. CORLEY, CHANDRA PATTERSON, MARIAH R. BAUGHN
  • Ras proteins
    Patent number: 6391580
    Abstract: The invention provides seven human Ras proteins (RASP) and polynucleotides which identify and encode RASP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of RASP.
    Type: Grant
    Filed: May 8, 1998
    Date of Patent: May 21, 2002
    Assignee: Incyte Genomics, Inc.
    Inventors: Jennifer L. Hillman, Y. Tom Tang, Preeti Lal, Karl J. Guegler, Neil C. Corley, Chandra Patterson, Sajeev Batra, Mariah R. Baughn
  • Human regulatory molecules
    Publication number: 20020058264
    Abstract: The invention provides human regulatory molecules and the polynucleotides which identify and encode them. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention further provides methods for diagnosing and treating disorders associated with expression of human regulatory molecules.
    Type: Application
    Filed: September 26, 2001
    Publication date: May 16, 2002
    Applicant: Incyte Pharmaceuticals, Inc
    Inventors: Preeti Lal, Jennifer L. Hillman, Olga Bandman, Purvi Shah, Janice Au-Young, Henry Yue, Karl J. Guegler, Neil C. Corley
  • Human pinch protein homolog
    Patent number: 6379904
    Abstract: The invention provides a human PINCH protein homolog (PINCH-PH) and polynucleotides which identify and encode PINCH-PH. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of PINCH-PH.
    Type: Grant
    Filed: March 20, 2000
    Date of Patent: April 30, 2002
    Assignee: Incyte Genomics, Inc.
    Inventors: Preeti Lal, Karl J. Guegler, Neil C. Corley
  • Novel human protein kinases
    Publication number: 20020042114
    Abstract: The present invention provides novel human protein kinases (HPK) and polynucleotides which identify and encode HPK. The invention provides for genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding HPK. The invention also provides for pharmaceutical compositions comprising HPK or antagonists of HPK, and antibodies which specifically bind HPK. Additionally, the invention provides antisense molecules to HPK for treatment or prevention of diseases associated with abnormal expression of HPK.
    Type: Application
    Filed: March 15, 2001
    Publication date: April 11, 2002
    Applicant: Incyte Pharmaceuticals, Inc.
    Inventors: Janice Au-Young, Karl J. Guegler, Phillip R. Hawkins