Patents by Inventor Kazuhiko Ishihara
Kazuhiko Ishihara has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220235482Abstract: A surface-treated steel sheet including: a steel sheet; and a nickel-cobalt-iron diffusion layer formed on the steel sheet as an outermost layer. When the intensities for Ni, Co and Fe are consecutively measured from a surface of the nickel-cobalt-iron diffusion layer in the depth direction by radio frequency glow discharge optical emission spectrometry, and the concentration of Ni, Co and Fe at each of depth positions are determined based on the intensities for Ni, Co, and Fe, a Co concentration gradient APco ranging from a depth position Dco MAX to a depth position DCo_15% is 33% by mass/0.1 ?m or less.Type: ApplicationFiled: April 27, 2020Publication date: July 28, 2022Applicant: TOYO KOHAN CO., LTD.Inventors: Yuji NAKANO, Koh YOSHIOKA, Kazuhiko ISHIHARA
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Patent number: 11192990Abstract: A resin molded body, includes: a polyolefin element including a crystalline region and an amorphous region; and a hydrophilic polymer contained in a region from a surface of the polyolefin element to part of the amorphous region located below the surface. Or, a method for producing a resin molded body, includes: preparing a polyolefin element including a crystalline region and an amorphous region; forming a coating of a hydrophilic polymer on a surface of the polyolefin element; and applying heat treatment to the polyolefin element on which the coating of the hydrophilic polymer is formed, wherein by applying the heat treatment, the coating of the hydrophilic polymer is immersed in a region from the surface to part of the amorphous region located below the surface.Type: GrantFiled: March 20, 2018Date of Patent: December 7, 2021Assignees: Kyocera Corporation, The University of TokyoInventors: Masayuki Kyomoto, Kazuhiko Ishihara
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Patent number: 11111367Abstract: A resin molded body includes: a polyolefin element formed of polyolefin, including a crystalline region and an amorphous region; and a hydrophilic copolymer contained in at least part of a surface of the polyolefin element, the hydrophilic copolymer including a copolymer of 2-methacryloyloxyethyl phosphorylcholine (MPC) of 45% or greater on a mole fraction basis and at least one other monomer. In the resin molded body, the MPC polymer is immersed through the surface by applying heat treatment.Type: GrantFiled: March 20, 2018Date of Patent: September 7, 2021Assignees: KYOCERA CORPORATION, THE UNIVERSITY OF TOKYOInventors: Masayuki Kyomoto, Kazuhiko Ishihara
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Publication number: 20210205495Abstract: In a molding step as step A1, a polymer material is molded and a substrate having a predetermined shape is obtained. In a polymer film forming step as step A2, the obtained substrate is immersed in a treatment aqueous solution including a compound having a phosphorylcholine group and a water-soluble inorganic salt, and the substrate in that state is irradiated with an ultraviolet light to form on a surface of the substrate a polymer film including polymer chains caused by polymerization of the compound having a phosphorylcholine group. A method for manufacturing a sliding member for an artificial joint as mentioned above makes it possible to efficiently manufacture a sliding member for an artificial joint having excellent wear resistance.Type: ApplicationFiled: February 16, 2017Publication date: July 8, 2021Applicants: KYOCERA Corporation, The University of TokyoInventors: Shihori YAMANE, Masayuki KYOMOTO, Kazuhiko ISHIHARA
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Patent number: 11015078Abstract: [Problem] To provide a surface treatment polymer. [Solution] A compound represented by formula (1), and a surface treatment agent including the compound.Type: GrantFiled: July 5, 2017Date of Patent: May 25, 2021Assignee: THE UNIVERSITY OF TOKYOInventors: Kazuhiko Ishihara, Yoshihiro Kiritoshi
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Patent number: 10927206Abstract: Provided are a copolymer having biocompatibility sufficient for use in medical material applications, and a method of forming a crosslinked body, the method including imparting biocompatibility to a substrate surface through the use of the copolymer. More specifically, a protein adsorption-suppressing effect and a cell adhesion-suppressing effect, which are features of a phosphorylcholine group, are imparted to the substrate surface. It has been found that a copolymer containing a phosphorylcholine constitutional unit and a photoreactive constitutional unit, or a copolymer containing a phosphorylcholine constitutional unit, a photoreactive constitutional unit, and a hydrophobic constitutional unit can impart a protein adsorption-suppressing effect and a cell adhesion-suppressing effect to a substrate surface through a simple approach called photoirradiation.Type: GrantFiled: June 28, 2017Date of Patent: February 23, 2021Assignees: NOF CORPORATION, THE UNIVERSITY OF TOKYOInventors: Kazuhiko Ishihara, Masaru Matsuda, Tomozumi Noda, Satoshi Yamada, Nobuyuki Sakamoto
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Patent number: 10829710Abstract: Provided is a lubricity-imparting agent that can impart durable lubricity (in particular, lubricity at the time of wetting) to a substrate. It has been found that a lubricity-imparting agent including a copolymer containing a constitutional unit (A) based on 2-methacryloyloxyethyl phosphorylcholine and a constitutional unit (B) based on a photoreactive functional group-containing monomer, or a copolymer containing a constitutional unit (A) based on 2-methacryloyloxyethyl phosphorylcholine, a constitutional unit (B) based on a photoreactive functional group-containing monomer, and a constitutional unit (C) based on a hydrophobic group-containing monomer can impart durable lubricity to a substrate surface through a simple approach called photoirradiation.Type: GrantFiled: June 28, 2017Date of Patent: November 10, 2020Assignees: NOF CORPORATION, THE UNIVERSITY OF TOKYOInventors: Kazuhiko Ishihara, Tomozumi Noda, Masaru Matsuda, Satoshi Yamada, Nobuyuki Sakamoto
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Publication number: 20200190298Abstract: A resin molded body includes: a polyolefin element formed of polyolefin, including a crystalline region and an amorphous region; and a hydrophilic copolymer contained in at least part of a surface of the polyolefin element, the hydrophilic copolymer including a copolymer of 2-methacryloyloxyethyl phosphorylcholine (MPC) of 45% or greater on a mole fraction basis and at least one other monomer. In the resin molded body, the MPC polymer is immersed through the surface by applying heat treatment.Type: ApplicationFiled: March 20, 2018Publication date: June 18, 2020Applicants: KYOCERA Corporation, The University of TokyoInventors: Masayuki KYOMOTO, Kazuhiko ISHIHARA
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Publication number: 20190345316Abstract: A resin molded body, includes: a polyolefin element including a crystalline region and an amorphous region; and a hydrophilic polymer contained in a region from a surface of the polyolefin element to part of the amorphous region located below the surface. Or, a method for producing a resin molded body, includes: preparing a polyolefin element including a crystalline region and an amorphous region; forming a coating of a hydrophilic polymer on a surface of the polyolefin element; and applying heat treatment to the polyolefin element on which the coating of the hydrophilic polymer is formed, wherein by applying the heat treatment, the coating of the hydrophilic polymer is immersed in a region from the surface to part of the amorphous region located below the surface.Type: ApplicationFiled: March 20, 2018Publication date: November 14, 2019Applicants: KYOCERA Corporation, The University of TokyoInventors: Masayuki KYOMOTO, Kazuhiko ISHIHARA
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Publication number: 20190316054Abstract: Provided is a lubricity-imparting agent that can impart durable lubricity (in particular, lubricity at the time of wetting) to a substrate. It has been found that a lubricity-imparting agent including a copolymer containing a constitutional unit (A) based on 2-methacryloyloxyethyl phosphorylcholine and a constitutional unit (B) based on a photoreactive functional group-containing monomer, or a copolymer containing a constitutional unit (A) based on 2-methacryloyloxyethyl phosphorylcholine, a constitutional unit (B) based on a photoreactive functional group-containing monomer, and a constitutional unit (C) based on a hydrophobic group-containing monomer can impart durable lubricity to a substrate surface through a simple approach called photoirradiation.Type: ApplicationFiled: June 28, 2017Publication date: October 17, 2019Applicants: NOF CORPORATION, THE UNIVERSITY OF TOKYOInventors: Kazuhiko ISHIHARA, Tomozumi NODA, Masaru MATSUDA, Satoshi YAMADA, Nobuyuki SAKAMOTO
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Publication number: 20190256731Abstract: [Problem] To provide a surface treatment polymer.Type: ApplicationFiled: July 5, 2017Publication date: August 22, 2019Applicant: THE UNIVERSITY OF TOKYOInventors: Kazuhiko ISHIHARA, Yoshihiro KIRITOSHI
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Patent number: 10323132Abstract: Provided are a copolymer having enough biocompatibility to be used in a medical material application, and a method of forming a crosslinked body, which involves modifying a substrate surface with the copolymer so that the surface may be biocompatible. More specifically, a protein adsorption-suppressing effect and a cell adhesion-suppressing effect, which are features of a phosphorylcholine group, are imparted to the substrate surface. It has been found that the object is achieved by a copolymer containing a phosphorylcholine constitutional unit, a hydrophobic constitutional unit, and a photoreactive constitutional unit at a specific ratio.Type: GrantFiled: March 2, 2016Date of Patent: June 18, 2019Assignees: NOF Corporation, The University of TokyoInventors: Kazuhiko Ishihara, Yuuki Inoue, Kyoko Fukazawa, Masaru Matsuda, Satoshi Yamada, Tomozumi Noda
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Publication number: 20190153137Abstract: Provided are a copolymer having biocompatibility sufficient for use in medical material applications, and a method of forming a crosslinked body, the method including imparting biocompatibility to a substrate surface through the use of the copolymer. More specifically, a protein adsorption-suppressing effect and a cell adhesion-suppressing effect, which are features of a phosphorylcholine group, are imparted to the substrate surface. It has been found that a copolymer containing a phosphorylcholine constitutional unit and a photoreactive constitutional unit, or a copolymer containing a phosphorylcholine constitutional unit, a photoreactive constitutional unit, and a hydrophobic constitutional unit can impart a protein adsorption-suppressing effect and a cell adhesion-suppressing effect to a substrate surface through a simple approach called photoirradiation.Type: ApplicationFiled: June 28, 2017Publication date: May 23, 2019Applicants: NOF CORPORATION, THE UNIVERSITY OF TOKYOInventors: Kazuhiko ISHIHARA, Masaru MATSUDA, Tomozumi NODA, Satoshi YAMADA, Nobuyuki SAKAMOTO
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Patent number: 10030283Abstract: Provided is a method for producing a surface-treated steel sheet for battery containers including: a first process of forming an iron-nickel alloy plating layer on at least one side of a steel sheet; a second process of forming a nickel plating layer on the iron-nickel alloy plating layer; and a third process of performing a thermal treatment after forming the nickel plating layer to form an iron-nickel alloy layer having an outermost surface, at which a content ratio of Fe atoms is 12 to 55% by atom, on an outermost layer by thermal diffusion. The invention makes it possible to provide the method for producing the surface-treated steel sheet for battery containers that can suppress the elution of iron inside the battery when being used for a battery container, whereby the service life of the battery can be extended and battery characteristics such as discharge characteristics can be improved.Type: GrantFiled: April 18, 2014Date of Patent: July 24, 2018Assignee: TOYO KOHAN CO., LTD.Inventors: Shinichirou Horie, Koh Yoshioka, Kazuhiko Ishihara
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Publication number: 20180051140Abstract: Provided are a copolymer having enough biocompatibility to be used in a medical material application, and a method of forming a crosslinked body, which involves modifying a substrate surface with the copolymer so that the surface may be biocompatible. More specifically, a protein adsorption-suppressing effect and a cell adhesion-suppressing effect, which are features of a phosphorylcholine group, are imparted to the substrate surface. It has been found that the object is achieved by a copolymer containing a phosphorylcholine constitutional unit, a hydrophobic constitutional unit, and a photoreactive constitutional unit at a specific ratio.Type: ApplicationFiled: March 2, 2016Publication date: February 22, 2018Applicants: THE UNIVERSITY OF TOKYO, NOF CORPORATIONInventors: Kazuhiko Ishihara, Yuuki Inoue, Kyoko Fukazawa, Masaru Matsuda, Satoshi Yamada, Tomozumi Noda
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Patent number: 9887396Abstract: Provided is a surface-treated steel sheet for battery containers (100) that is obtained in such a manner that after iron-nickel alloy plating is performed on a steel sheet (10), a thermal treatment is performed and is characterized in that an outermost layer is an iron-nickel alloy layer (20), and the iron-nickel alloy layer (20) has an average crystal size of 1 to 8 ?m at the outermost surface thereof. The present invention makes it possible to provide the surface-treated steel sheet for battery containers that can suppress the elution of iron inside the battery when being used for a battery container, whereby the service life of the battery can be extended and battery characteristics such as discharge characteristics is improved, and to provide a battery container and a battery that can be obtained using the surface-treated steel sheet for battery containers.Type: GrantFiled: January 29, 2016Date of Patent: February 6, 2018Assignee: Toyo Kohan Co., Ltd.Inventors: Koh Yoshioka, Shinichirou Horie, Kazuhiko Ishihara
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Publication number: 20160211489Abstract: Provided is a surface-treated steel sheet for battery containers (100) that is obtained in such a manner that after iron-nickel alloy plating is performed on a steel sheet (10), a thermal treatment is performed and is characterized in that an outermost layer is an iron-nickel alloy layer (20), and the iron-nickel alloy layer (20) has an average crystal size of 1 to 8 ?m at the outermost surface thereof. The present invention makes it possible to provide the surface-treated steel sheet for battery containers that can suppress the elution of iron inside the battery when being used for a battery container, whereby the service life of the battery can be extended and battery characteristics such as discharge characteristics is improved, and to provide a battery container and a battery that can be obtained using the surface-treated steel sheet for battery containers.Type: ApplicationFiled: January 29, 2016Publication date: July 21, 2016Inventors: Koh YOSHIOKA, Shinichirou HORIE, Kazuhiko ISHIHARA
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Publication number: 20160168657Abstract: Provided is a method for producing a surface-treated steel sheet for battery containers including: a first process of forming an iron-nickel alloy plating layer on at least one side of a steel sheet; a second process of forming a nickel plating layer on the iron-nickel alloy plating layer; and a third process of performing a thermal treatment after forming the nickel plating layer to form an iron-nickel alloy layer having an outermost surface, at which a content ratio of Fe atoms is 12 to 55% by atom, on an outermost layer by thermal diffusion. The invention makes it possible to provide the method for producing the surface-treated steel sheet for battery containers that can suppress the elution of iron inside the battery when being used for a battery container, whereby the service life of the battery can be extended and battery characteristics such as discharge characteristics can be improved.Type: ApplicationFiled: April 18, 2014Publication date: June 16, 2016Inventors: Shinichirou HORIE, Koh YOSHIOKA, Kazuhiko ISHIHARA
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Patent number: 9216241Abstract: An object is to provide a medical device having excellent antithrombotic and sliding characteristics, which can exert a cell adhesion inhibitory effect. A medical device comprising: a substrate capable of forming hydroxyl groups; and a biocompatible material layer laminated on the substrate at an appropriate position, wherein the hydroxyl groups are formed on a surface of the substrate at least at a required position by a surface treatment, while the biocompatible material layer is formed from a polymer containing phosphorylcholine groups, and wherein the substrate and the biocompatible material layer are joined via a binder layer formed from silica being covalently bonded with the hydroxyl groups and the biocompatible material, respectively.Type: GrantFiled: December 19, 2008Date of Patent: December 22, 2015Assignees: KYOCERA MEDICAL CORPORATION, THE UNIVERSITY OF TOKYOInventors: Masayuki Kyomoto, Kazuhiko Ishihara, Kozo Nakamura, Yoshio Takatori, Hiroshi Kawaguchi, Toru Moro
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Patent number: 9192694Abstract: The object of the present invention is to provide a sliding member, a prosthesis and a method of producing the sliding member, which can suppress production of abrasive wear debris by suppressing friction of the sliding section, and also can maintain satisfactory mechanical characteristics in vivo. A sliding member comprising: a substrate 1 capable of forming hydroxyl groups; and a biocompatible material layer 4 laminated on appropriate sections of the substrate 1, wherein hydroxyl groups are formed on at least a required section of a surface of the substrate 1 by surface treating to form a surface-treated layer 2, while the biocompatible material layer 4 is formed from a polymer containing phosphorylcholine groups, and wherein the substrate 1 and the biocompatible material layer 4 are joined via a binder layer 3 formed from silica being covalently bonded with the hydroxyl groups and the biocompatible material, respectively.Type: GrantFiled: October 2, 2008Date of Patent: November 24, 2015Assignees: KYOCERA MEDICAL CORPORATION, THE UNIVERSITY OF TOKYOInventors: Masayuki Kyomoto, Kazuhiko Ishihara, Kozo Nakamura, Yoshio Takatori, Hiroshi Kawaguchi, Toru Moro