Abstract: The present invention discloses two new related substances (6) and (7) of Anastrozole synthesis from Q.A. Salt (5) as in Scheme-1 and purification procedures to get Anastrozole (1) free from (6) and (7).

Abstract: A novel chimeric protein of rabies virus designed to express a chimeric G protein at a high level in transgenic plants. A gene was also designed and chemically synthesised to encode the chimeric G protein and expressed at high level in plant tissue. The gene was expressed in transgenic tobacco plants to examine its therapeutic efficacy against infection by rabies virus. The chimeric G protein was enriched in plant membranes. The BalbC mice were immunised with the plant leaf expressed G-protein. Plant derived chimeric G protein elicited higher immune response as compared to the commercial vaccine. The mice displayed protective immunity when they were challenged with live virus. Chimeric G protein expressed at high level in plant leaves was demonstrated to function as a commercially valuable subunit vaccine against rabies virus infection.

Abstract: A method and system for reducing channel changing time in multicast media, that can include the steps of receiving at least one of a plurality of available channels from a service provider at a residential gateway through a network, ranking the popularity of at least one of the available channels at a ranking engine connected to the residential gateway, and requesting to receive a number of the channels available from the service provider at the residential gateway based on the ranking. The rank is at least partly based on the data stored in the database.

Abstract: A combustor minimizes combustion emissions at a lower level of combustion dynamics during combustor even fuel-split conditions by varying the fuel impedance through geometrical changes or inert addition in various nozzle groups than that achievable during combustor even fuel-split conditions with a multi-fuel nozzle combustor using a nozzle fuel impedance that is common to all nozzles while emitting substantially the same level of combustion emissions.

Abstract: Fullerenes, when irradiated with electromagnetic radiation, generate acoustic waves. A photoacoustic tomography method using a material comprising fullerenes is disclosed that includes irradiating the material with a radiation beam such as a laser. The resultant photoacoustic effect produced by the material is detected by at least one detector. A photoacoustic tomography system using a material comprising fullerenes is also described.

Abstract: A pet travel safety device is provided for use with a vehicle seatbelt system to controllably restrain movement of a pet in a vehicle during a collision or sudden deceleration of the vehicle. In one embodiment, a safety restrainer may secure a pet in a vehicle having a seat belt with a first prong configured to latch into a first buckle of a shoulder/lap belt combination system. The safety restrainer may comprise a restraint assembly including a restraint strap having a first strap end and a second strap end which are configured to releasably couple to each other. The safety restrainer may further comprise a harness configured to couple to the restraint assembly. The harness may include a first harness end and a second harness end. The first harness end comprises a first connector to releasably couple to the first prong and the second harness end comprises a second connector to releasably couple to the first buckle. The harness may include first and second harness portions.

Abstract: The present invention relates to a system and a method for analysis of a DNA sequence by converting the DNA sequence into a unique number string using a genomic number system in order to extract and/or analyze biological information. The invention is particularly useful in the development of new drugs or active chemical agents.

Abstract: A solution for scalable key archival includes, at a network device, determining whether a key management device that is not part of a current key management device configuration has been newly added to a network. The method also includes, if the key management device has been newly added to the network, determining whether the network device has a first application program interface (API) or device driver for communicating with the key management device. The method also includes, if the network device does not have the first API, obtaining the API. The method also includes creating a binding between a virtual device driver of the network device and the key management device via the first API, the network device having a second API for communications between the virtual device driver and a security processor of the network device. The security processor communicates with the key management device using the second API.

Abstract: A gas turbine engine control system comprises a data acquisition and analysis system for receiving a signal from a combustion dynamics sensor and providing an output signal and a combustion dynamics control system for controlling combustion dynamics based on the output signal. The control system is associated with a purge-air flow and comprises an acoustic driver, or a flow-manipulating device, or both to perturb the purge-air flow entering the combustor can for controlling combustion dynamics.

Abstract: A technique for using a key repository to store data encryption keys provides a way to access key records in the key repository using a key identifier constructed from a media identifier associated with a data storage medium on which encrypted data is or will be stored. The media identifier is hashed and added to a counter value to produce the key identifier. In some embodiments, the technique is implemented in an encryption switch that provides data-at-rest encryption for a storage access network, but in other embodiments, the technique may be implemented in other devices, including data storage devices and hosts.

Abstract: Methods and compositions for treating a subject having age-related macular degeneration (AMD), methods of assaying human macular degeneration (MD), and methods and kits for assaying potential therapeutic agents for treatment of human MD are provided herein.

Abstract: A microfluidic device may employ one or more sorting stations for separating target species from other species in a sample. The separation is driven by magnetophoresis. A sorting station generally includes separate buffer and sample streams. A magnetic field gradient applied to the sorting station deflects the flow path of magnetic particles (which selectively label the target species) from a sample stream into a buffer stream. The buffer stream leaving the sorting station is used to detect or further process purified target species labeled with the magnetic particles.

Abstract: Disclosed herein is a process for producing bisphosphonic acids and salts thereof. The process comprising reacting a carboxylic acid of Formula [I] with phosphorous acid and halophosphorus compound in the presence of a solvent selected from aliphatic hydrocarbon or water miscible cyclic ether. Further, the present invention also provides novel forms of bisphosphonic acids and process for preparation thereof.

Abstract: A virtual testbed for system verification test is provided in which emulated responses are associated with certain steps of a system verification test. The emulated responses can be manually entered or populated with previous test results obtained from execution of the emulation-enabled steps on a real testbed. When the emulation-enabled steps are executed, the system verification test uses the emulated responses as the responses corresponding to the actions of the emulation-enabled steps as if the steps were executed on the real testbed, without actually executing the emulation-enabled steps on the real testbed. Therefore, the virtual testbed of the present invention allows development of test scripts for system verification test without constant, actual access to the real testbed.

Abstract: A method for electron beam nanolithography without the need for development step involves depositing a film of a resist comprising functionalized fullerenes on a substrate, and writing features by exposure to an electron beam with an accelerating voltage and dose rate sufficient to promote heating or thermal degradation of the functionalized fullerene in the irradiated volume such that a pattern is generated without a subsequent development step or with an aqueous developer. Lithographic features of about 1 nm or greater can be formed.

Abstract: A combustor for a gas turbine engine and related method is provided in which a plurality of combustor cans are selectively adapted with corresponding resonators. The resonators may, for example, be attached to every can in the consecutive arrangement of combustor cans, every other can, every third can or the like, and may be tuned to the same or first, second, third, etc. frequencies of operation. Such selective tuning is configured to suppress one or more of out-of-phase and in-phase dynamic interaction of streams discharged from adjacent combustor cans by changing the frequencies of pressure oscillation instabilities across the arrangement of consecutive cans.

Abstract: A technique that may be used to configure a computer system to automatically search a video and select a frame within the video clip that best represents the content of that video. A frame contained in a video is identified. Luminance values for each pixel in a plurality of pixels contained in the frame are then generated. The frame is then selected as a poster frame for the video if a luminance value for at least one pixel in the plurality of pixels contained in the identified frame is outside a range of luminance values. The range of luminance values may be determined from a luminance value associated with a reference pixel contained in the frame.

Abstract: The present invention discloses modified process for preparing aromatase inhibitor Exemestane involving suitable oxidizing agents in suitable solvents.

Abstract: Disclosed herein is a polymeric composition comprising a polymeric composition comprising a first crosslinked network; and a second crosslinked network; wherein the first crosslinked network is crosslinked at a first stress and/or a first strain and the second crosslinked network is crosslinked at a second stress and/or a second strain; where the first stress and/or the first strain is different from the second stress and/or the second strain either in magnitude or direction. Disclosed herein is a method comprising subjecting a polymeric mass to a first stress and/or a first strain level; crosslinking the polymeric mass to form a first crosslinked network; subjecting the polymeric mass to a second stress and/or a second strain level; and crosslinking the polymeric mass to form a second crosslinked network; where the first stress and/or the first strain level is different from the second stress and/or the second strain level.

Abstract: Methods for active power management, i.e., the power management method may be activated in response to changes in the supply and demand of power in a system, are disclosed. The power management method may use dynamically collected data reporting levels of electrical power utilized by systems while matching them to the available power. One embodiment of the present invention may be applied in smaller or medium sized systems. Another embodiment of the present invention may be implemented making use of additional aircraft resources, such as an integrated modular avionics (IMA) line replaceable unit (LRU) in larger sized systems. Both of these embodiments may make use of data collected from systems utilizing or generating electrical via the bus power control unit (BPCU) LRU, the data processing taking place either locally in the BPCU (small or medium sized systems) or in the IMA (larger systems).