Abstract: A method to align a next generation sequencing read to a reference sequence includes: (a) receiving a sequencing read; (b) performing a first alignment of the sequencing read to a reference sequence so as to identify a target sequence within the reference sequence whereto the sequencing read maps; (c) selecting a first and a second anchor sequence; (d) attaching the first anchor sequence to the upstream region of the sequencing read and the second anchor sequence to the downstream region of the sequencing read so as to generate an extended sequencing read; (e) attaching the first anchor sequence to the upstream region of the target sequence and the second anchor sequence to the downstream region of the target sequence, so as to generate an extended target sequence; (f) performing a second alignment of the extended sequencing read to the extended target sequence, so that the second alignment is more correctly mapped to the target sequence than the first alignment; (g) identifying a position where one or more b

Abstract: A touch sensing method for a display with touch device having an image display period, which includes multiple execution time sections. Each execution time section has a display time division and a blank time division. A display procedure is executed in each display time division. A communicating procedure is executed in one of the blank time division. In the communicating procedure, an uplink signal is provided by the common electrodes for a first object to receive. Thus, the display with touch device has more time to detect more different kinds of touch objects.

Abstract: A miniaturized sensing probe and a manufacturing method thereof are provided. The miniaturized sensing probe includes: a probe substrate including a probe part and a circuit connection part; a sensor disposed on the probe part and electrically connected to the circuit connection part; and a needle unit used to accommodate the probe part of the probe substrate; wherein the sensor performs sensing when placed into an analyte through the needle unit and transmits a sensing signal through the circuit connection part. The miniaturized sensing probe of the present invention may be easily placed into the analyte without the use of other instrument or surgery. This means is of benefit to a clinician performing an early diagnosis on a patient with a peripheral vascular disease or monitoring the biological value of the muscle during surgery in real time.

Abstract: A method for producing an artificial sebum film is provided with in raw material component and relative ratio, 78.4%-2% of triglyceride, 1%-15% of wax and ester, 20%-35% of squalane, 0.1%-7% of free fatty acid, 0.1%-6% of phospholipid, 0.1%-10% of cholesterol ester, 0.1%-10% of cholesterol, 0.1%-10% of antioxidant and 0.1%-5% of cellular activity regulator. The invention modifies the proportion of raw material composition of the artificial sebum film to reduce the negative effect generated by oxidation, and increase the proportion of squalane, so that the skin under high pollution can restore to the normal equilibrium state. Further, antioxidants and cellular active regulators are added to prolong the oxidation time of artificial sebum film and replenish the adenosine triphosphate in the cells.

Abstract: Examples of techniques for patient-level analytics with sequential pattern mining are provided. In one example implementation according to aspects of the present description, a computer-implemented method includes: constructing a patient record; transforming, by a processing system, the patient record into a bitmap representation; and analyzing, by the processing system, the bitmap to identify a sequential pattern within the patient record on a per patient basis.

Abstract: A mobile communication device including a first RF device, a second RF device, and a controller is provided. The first and second RF devices perform wireless transmission and reception utilizing a first RAT and a second RAT, respectively. The controller detects, during a communication with a first cell using a first subscriber identity, an incoming event for making a voice call or conducting a data session using a second subscriber identity via the second RF device, and switches the communication associated with the first subscriber identity to a second cell which utilizes the first RAT in a frequency band on which dual connectivity over the first and second RATs is supported, or enables the voice call associated with the second subscriber identity to be made via the first RF device when the communication associated with the first subscriber identity is performed via the second RF device.

Abstract: An assembled multifunctional cylindrical bag has an outer bag assembly and an inner cylinder assembly detachably mounted in the outer bag assembly. The inner cylinder assembly is made of a rigid material to support the outer bag assembly so that the outer bag assembly can stand while remaining its shape to provide seating. The inner cylinder assembly has an inner cylinder with a thermal insulation function for storage of foods or drinks. The outer bag assembly can be implemented in any forms such us balls or sports-related equipment for commercial purposes. When the inner cylinder assembly is detached from the outer bag assembly, the outer bag assembly is adapted to store any items including sports accessories. Therefore, the assembled multifunctional cylindrical bag offers different functions for the user to choose from to fit for various occasions.

Abstract: A plug connector assembly includes: a plug connector having a cage, and a PCB received in the cage, the PCB including a mating end for being mated with a mating connector and an opposite connecting end, the connecting end comprising a first row of pads and a second row of pads disposed at one side of the PCB; at least one cable electrically connected to the connecting end, the at least one cable comprising a number of core wires, the core wires comprising a first group of core wires and a second group of core wires extending beyond the first group of core wires, the first group of core wires soldered to the first row of pads, the second group of core wires soldered to the second row of pads; and an insulative member isolating a soldering area of the first and second group of core wires.

Abstract: Embodiments include methods, systems and computer program products for reducing feature space in analysis of medical data. Aspects include receiving patient temporal traces. Aspects also include conducting sequential pattern mining on the patient temporal traces to produce sequential features. Aspects also include clustering the sequential features with a similarity metric. Aspects also include analyzing the clustered features to predict a healthcare outcome.

Abstract: The woven textile has a first end and an opposite second end. A longitudinal direction is defined by the first end and the second end. The woven textile includes an upper layer, a lower layer, and at least one binding thread. The upper layer includes at least one first braid woven by a plurality of filaments and extending in a meandering way to form a plurality of hollow portions. The lower layer includes at least one second braid woven by a plurality of filaments and extending in a meandering way to form a plurality of hollow portions. The binding thread fixes the first braid and the second braid together by weaving so that the upper layer and the lower layer are positioned by the binding thread.

Abstract: A multi-cell coordination system and a channel calibration method thereof are provided. A reference apparatus receives a beam-precoding downlink reference signal via a directional beam from a base station. The base station receives a beam-precoding uplink reference signal via the directional beam from the reference apparatus. The server receives uplink and downlink channel information, where the uplink channel information is generated based on the uplink reference signal, and the downlink channel information is generated based on the downlink reference signal. The server obtains a channel calibration coefficient according to the uplink and downlink channel information. The channel calibration coefficient is used for estimating a downlink channel. Accordingly, the problem of conventional coordination system can be solved, and the embodiment can be implemented in multi-beam base station.

Abstract: A woven textile and method for making the same are provided. The woven textile defines a longitudinal direction and a lateral direction relative to the longitudinal direction. The woven textile includes a plurality of lateral threads and a plurality of longitudinal threads, and each of the plurality of lateral threads winds back in the lateral direction to form a lateral space. The plurality of longitudinal threads are respectively disposed through the lateral space and wind back in the longitudinal direction to form a plurality of first eyelets, and the plurality of longitudinal threads then shift in the lateral direction, extend through respective ones of the plurality of first eyelets and wind back in the longitudinal direction to form a plurality of second eyelets.

Abstract: An input device for applying to a touch display device is provided. In a sub-signal transmitting section of the input device, the input device transmits a modulation signal corresponding to the state information. Since the length of time of sub-signal transmitting section of the input device is larger or at least equal to one time the length of time of the display section of the touch display device plus twice the length of time of the blank section of the touch display device, the sub-signal transmitting section overlaps at least one of the blank section. The touch display device can receive the modulation signal transmitted from the input device during the overlapping blank sections. Thus, the input device does not need to know the frame of the touch display device so that a receiving unit is reduced to decrease the cost.

Abstract: A package of electronic device including a substrate, at least one electronic device and an encapsulation layer is provided. The substrate has a device area and a light transmitting area located outside the device area. The at least one electronic device is disposed on the device area of the substrate. The encapsulation layer is disposed on the substrate and covers the at least one electronic device. The encapsulation layer extends continuously from the device area to the light transmitting area, and a nitrogen content of the encapsulation layer on the device area is higher than a nitrogen content of the encapsulation layer on the light transmitting area. A display panel is also provided.

Abstract: A device comprises a first interconnect structure over a first active device layer, a first power circuit in the first active device layer, a second active device layer over and in contact with the first interconnect structure, a first switch in the second active device layer, a second interconnect structure over and in contact with the second active device layer, a third active device layer over and in contact with the second interconnect structure, a second power circuit in the third active device layer and a third interconnect structure over and in contact with the third active device layer and connected to a power source, wherein the power source is configured to provide power to the first power circuit through the first switch.

Abstract: A glass production apparatus producing continuously curved glass for covers and containers includes a crucible, a calender device, a cutting device, a molding device, and a crystallizing device. The crucible melts glass raw material and outputs a glass melt to calender device. The calender device rolls and presses the glass melt to prepare a glass belt with a preset temperature. The cutting device cuts the glass belt with the preset temperature into glass members. The molding device include at least one molding mold and a manipulator. Each of the at least one molding mold curves at least one portion of the glass member with the preset temperature to prepare a curved glass member. The manipulator transfers the curved glass member to the crystallizing device, the crystallizing device crystallizes the curved glass member to prepare a curved crystalline glass member. A method for manufacturing such glass is also provided.

Abstract: A production apparatus making continuously curved crystalline glass as a cover or container includes a melting device, a drainage device, a molding device, and a crystallizing device. The melting device melts glass raw material to form a glass melt. The drainage device drains the glass melt to the molding device. The molding device includes a rotating table and a plurality of molding molds thereon. Each molding mold can be moved toward or away from the drainage device by the rotating table. Each molding mold has a molding cavity. At least one part of the molding cavity includes a plane, and at least one part of the molding cavity includes a curved surface to extrude the glass melt with such different surface forms. The crystallizing device crystallizes the curved glass member to achieve the curved crystallized glass member. A method for manufacturing such glass is also provided.

Abstract: A capacitive sensing and sampling circuit and method thereof are disclosed. The capacitive sensing and sampling circuit has a voltage source, a sensing unit and a detecting circuit. The detecting unit has a first sensing output unit, a second sensing output unit and a sampling unit. The first and second sensing output units are electrically connected to an output of the sensing unit and the sampling unit. Therefore, by increasing the number of alternatively sensing the capacitive sensing component to obtain more capacitive signals, the number of sampling the sensed capacitive signal is relatively increased. Therefore, the white noise interference for the capacitive sensing and sampling circuit is effectively suppressed, so the signal-to-noise ratio is increased and accuracy of detecting coordinates of the touch object is increased.

Abstract: The present invention relates to the area of ATG4-related disorders. More particularly, the present invention relates to a method of treating an ATG4B-related disorder comprising a step of administering a subject with an effective amount of tioconazole. The present invention relates also to a method of increasing a subject's responsiveness to a therapy for a cancer comprising inhibition of ATG4B activity in cells; said method comprises administering the subject with an effective amount of tioconazole. The present invention also relates to a method for enhancing or inducing a response in a cancer cell consisting of cytotoxicity, chemosensitivity or starvation-sensitivity; said method comprises administering a subject with an effective amount of tioconazole to inhibit ATG4B's activity.

Abstract: A shoelace includes a tubular body woven by first threads, second threads, third threads, and fourth threads. Each first thread and each second thread are made of TPU. Each third thread and each fourth thread are made of polyester. Each first thread and each third thread are left-handed helices. Each second thread and each fourth thread are right-handed helices. Each first thread is parallel to each third thread. Each second thread is parallel to each fourth thread. The first threads and the third threads are alternately arranged. The second threads and the fourth threads are alternately arranged and are woven with the first threads and the third threads. Each first thread and each second thread have a smaller denier than that of each third thread and each fourth thread.